PL1901755T3 - Nowe kompozycje farmaceutyczne zawierające kwas hialuronowy lub jego pochodne i kolagenazę do miejscowego leczenia ran, oparzeń i owrzodzeń - Google Patents

Nowe kompozycje farmaceutyczne zawierające kwas hialuronowy lub jego pochodne i kolagenazę do miejscowego leczenia ran, oparzeń i owrzodzeń

Info

Publication number
PL1901755T3
PL1901755T3 PL06754678T PL06754678T PL1901755T3 PL 1901755 T3 PL1901755 T3 PL 1901755T3 PL 06754678 T PL06754678 T PL 06754678T PL 06754678 T PL06754678 T PL 06754678T PL 1901755 T3 PL1901755 T3 PL 1901755T3
Authority
PL
Poland
Prior art keywords
ulcers
wounds
burns
derivatives
hyaluronic acid
Prior art date
Application number
PL06754678T
Other languages
English (en)
Inventor
Susanna Vaccaro
Giovanni Gennari
Lanfranco Callegaro
Antonio Giannelli
Salvatore Caruso
Original Assignee
Fidia Farm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Farm Spa filed Critical Fidia Farm Spa
Publication of PL1901755T3 publication Critical patent/PL1901755T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886Metalloendopeptidases (3.4.24), e.g. collagenase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728Hyaluronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24Metalloendopeptidases (3.4.24)
    • C12Y304/24003Microbial collagenase (3.4.24.3)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PL06754678T 2005-07-07 2006-07-05 Nowe kompozycje farmaceutyczne zawierające kwas hialuronowy lub jego pochodne i kolagenazę do miejscowego leczenia ran, oparzeń i owrzodzeń PL1901755T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT000207A ITPD20050207A1 (it) 2005-07-07 2005-07-07 Nuove composizioni farmaceutiche contenenti acido ialuronico e collagenas nel trattamento topico di ferite, ustioni ed ulcere
PCT/EP2006/006616 WO2007006484A1 (en) 2005-07-07 2006-07-05 New pharmaceutical compositions containing hyaluronic acid and collagenase for the topical treatment of wounds, burns and ulcers
EP06754678A EP1901755B1 (en) 2005-07-07 2006-07-05 New pharmaceutical compositions containing hyaluronic acid or its derivatives and collagenase for the topical treatment of wounds, burns and ulcers

Publications (1)

Publication Number Publication Date
PL1901755T3 true PL1901755T3 (pl) 2011-03-31

Family

ID=37023161

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06754678T PL1901755T3 (pl) 2005-07-07 2006-07-05 Nowe kompozycje farmaceutyczne zawierające kwas hialuronowy lub jego pochodne i kolagenazę do miejscowego leczenia ran, oparzeń i owrzodzeń

Country Status (15)

Country Link
US (3) US8900576B2 (pl)
EP (1) EP1901755B1 (pl)
JP (1) JP5322637B2 (pl)
AT (1) ATE480244T1 (pl)
AU (1) AU2006268950B2 (pl)
BR (1) BRPI0612736A2 (pl)
CA (1) CA2613976C (pl)
DE (1) DE602006016799D1 (pl)
DK (1) DK1901755T3 (pl)
ES (1) ES2352350T3 (pl)
IT (1) ITPD20050207A1 (pl)
PL (1) PL1901755T3 (pl)
PT (1) PT1901755E (pl)
SI (1) SI1901755T1 (pl)
WO (1) WO2007006484A1 (pl)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011141611A1 (es) * 2010-05-14 2011-11-17 Sanidad Y Residencias 21, S.A., Composiciones de oleuropeína para cicatrización de heridas y úlceras en ancianos y/o diabéticos
CN102711808B (zh) 2009-12-08 2015-08-19 史密夫和内修整形外科股份公司 具有增强的酶活性的酶学伤口清创组合物
KR101831918B1 (ko) 2010-06-11 2018-02-27 한국원자력의학원 히알루론산의 탈아세틸화 가수분해효소, 및 이에 의해 탈아세틸화된 히알루론산 및 이의 유도체
ES2385239B1 (es) * 2010-09-30 2013-06-19 Proteos Biotech S.L.U. Uso de colagenasa g recombinante, colagenasa h recombinante y pz-peptidasa recombinante para el tratamiento de enfermedades que cursan con alteraciones del colágeno.
WO2013011514A1 (en) 2011-07-20 2013-01-24 Mediwound Ltd. Proteolytic extract from bromelain for the treatment of connective tissue disorders
CA2861033C (en) 2012-01-12 2017-07-25 Auxilium International Holdings, Inc. Clostridium histolyticum enzymes and methods for the use thereof
CN102552479B (zh) * 2012-01-19 2013-12-04 孙万奎 一种用于治疗糖尿病足的中药组合物
ES2424294B1 (es) * 2012-03-22 2014-07-21 Lipotec, S.A. Exopolisacárido para el tratamiento y/o cuidado de la piel, mucosas, cabello y/o uñas
ITPD20120118A1 (it) 2012-04-18 2013-10-19 Fidia Farmaceutici "nuovo processo di produzione e purificazione dell'enzima collagenasi da vibrio alginolyticus"
ITPD20120173A1 (it) * 2012-05-31 2013-12-01 Fidia Farmaceutici "nuovo sistema di rilascio di proteine idrofobiche"
ITPD20120360A1 (it) * 2012-11-30 2014-05-31 Fidia Farmaceutici "nuovi geli viscoelastici in chirurgia oftalmica"
WO2014179262A1 (en) * 2013-05-01 2014-11-06 Cole Researh & Design, Inc. Low molecular weight hyaluronic acid for treating keloid scars, hypertrophic scars and burn scars with contracture
US10117892B2 (en) * 2013-08-29 2018-11-06 Allergan, Inc. Devices and methods for reducing the appearance of cellulite
US20170020808A1 (en) * 2015-07-23 2017-01-26 Mary Kay Inc. Topical skin formulations
ES3036011T3 (en) 2017-03-01 2025-09-11 Endo Operations Ltd Apparatus and method for assessing and treating cellulite
KR20240001279A (ko) 2017-03-28 2024-01-03 엔도 벤쳐즈 리미티드 개선된 콜라게나제 생성 방법
CN111163784B (zh) * 2017-09-01 2024-07-26 黄玲惠 用于治疗蟹足肿的药物组合物及其用途
CN113759122A (zh) * 2020-06-05 2021-12-07 张曼 尿液蛋白质z及其多肽片段在烧伤中的应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4174389A (en) * 1977-05-13 1979-11-13 Cope Louise A Ophthalmic use of collagenase
IT1212892B (it) * 1983-10-11 1989-11-30 Della Valle Francesco Acido ialuronico ottenuto per mezzodi filtrazione molecolare sprovvisto di attivita' infiammatoria e sua utilizzazione terapeutica
CA1227132A (fr) * 1983-01-05 1987-09-22 Robert J. Weill Preparation a activite collagenolytique ayant une activite elevee et compositions pharmaceutiques la contenant
DE3504905A1 (de) 1985-02-13 1986-08-14 J. Kühn GmbH & Co Präzisionswerkzeug KG, 4270 Dorsten Werkzeughalter o.dgl.
US4851521A (en) * 1985-07-08 1989-07-25 Fidia, S.P.A. Esters of hyaluronic acid
JP3449738B2 (ja) * 1991-07-10 2003-09-22 武田薬品工業株式会社 水溶性組成物
US5393792A (en) * 1991-11-20 1995-02-28 Advance Biofactures Of Curacao, N.V. High dosage topical forms of collagenase
IL100112A (en) * 1991-11-21 1996-01-31 Yeda Res & Dev Microdelivery device for enhanced drug administration to the eye
DE4200080A1 (de) * 1992-01-03 1993-09-30 Reinmueller Johannes Pharmazeutische Zusammensetzung zur Wund-, Narben- und Keloidbehandlung
WO1994024273A1 (en) * 1993-04-16 1994-10-27 Baxter International Inc. Stable collagenase compositions and methods for their preparation
EP0637450A3 (en) 1993-08-04 1995-04-05 Collagen Corp Method and composition for resuscitation of hereditary tissue.
US5589171A (en) * 1994-08-22 1996-12-31 Advance Biofactures Of Curacao Treatment of Dupuytren's disease with collagenase
US5718897A (en) 1995-06-07 1998-02-17 Trustees Of Tufts College Enhancing keratinocyte migration and proliferation
DE19641672A1 (de) * 1996-10-10 1998-04-16 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen auf der Basis von ethylenoxidfreien und propylenoxidfreien Emulgatoren zur Herstellung von Mikroemulsionsgelen
US6120751A (en) * 1997-03-21 2000-09-19 Imarx Pharmaceutical Corp. Charged lipids and uses for the same
US6086872A (en) * 1997-03-27 2000-07-11 Advance Biofactures Of Curacao, Nv Amelioration of dupuytren's disease
IT1302534B1 (it) * 1998-12-21 2000-09-05 Fidia Advanced Biopolymers Srl Composizioni iniettabili, biocompatibili e biodegradabili comprendentialmeno un derivato dell'acido ialuronico, cellule condrogeniche, per
IT1306679B1 (it) * 1999-06-29 2001-10-02 Fidia Advanced Biopolymers Srl Uso dei derivati dell'acido ialuronico per la preparazione dicomposizoni farmaceutiche e biomateriali per la prevenzione della
JP2002020279A (ja) * 2000-06-30 2002-01-23 Taisho Pharmaceut Co Ltd 点眼液
DE10246340A1 (de) * 2002-10-04 2004-04-29 Wohlrab, David, Dr. Kombinationspräparat aus Hyaluronsäure und mindestens einem Lokalanästhetikum und dessen Verwendung
EP1433845A1 (en) * 2002-12-23 2004-06-30 Georg-August-Universität Clostridium tetani collagenase and uses thereof

Also Published As

Publication number Publication date
US20170209552A1 (en) 2017-07-27
US20140377249A1 (en) 2014-12-25
US9603910B2 (en) 2017-03-28
CA2613976A1 (en) 2007-01-18
JP2009500367A (ja) 2009-01-08
EP1901755A1 (en) 2008-03-26
US11040089B2 (en) 2021-06-22
WO2007006484A1 (en) 2007-01-18
US8900576B2 (en) 2014-12-02
ES2352350T3 (es) 2011-02-17
HK1116683A1 (en) 2009-01-02
EP1901755B1 (en) 2010-09-08
ATE480244T1 (de) 2010-09-15
US20080206228A1 (en) 2008-08-28
AU2006268950B2 (en) 2011-01-06
SI1901755T1 (sl) 2011-01-31
CA2613976C (en) 2013-11-19
DK1901755T3 (da) 2011-01-10
ITPD20050207A1 (it) 2007-01-08
PT1901755E (pt) 2010-12-16
DE602006016799D1 (de) 2010-10-21
BRPI0612736A2 (pt) 2012-10-02
AU2006268950A1 (en) 2007-01-18
JP5322637B2 (ja) 2013-10-23

Similar Documents

Publication Publication Date Title
SI1901755T1 (sl) Novi farmacevtski sestavki, ki vsebujejo hialuronsko kislino ali njene derivate in kolagenazo, za topično zdravljenje ran, opeklin in ulkusov
CA2931174C (en) No-emitting medical dressing comprising an no-generating module and a radiation-emitting module
IL154888A (en) Aqueous Pharmaceutical Gel Preparation Containing At least One Vitamin D or One Vitamin D Analog At least One Corticosteroid
UY27486A1 (es) Queratinocitos utilizables como sustancia biológicamente activa en el tratamiento de heridas
UA96965C2 (ru) ЗАМЕЩЕННЫЕ ПРОИЗВОДНЫЕ 2,3-ДИГИДРОИМИДАЗО[1,2-с]ХИНАЗОЛИНА, ПОЛЕЗНЫЕ ДЛЯ ЛЕЧЕНИЯ ГИПЕРПРОЛИФЕРАТИВНЫХ НАРУШЕНИЙ И БОЛЕЗНЕЙ, СВЯЗАННЫХ С АНГИОГЕНЕЗОМ
TW200605870A (en) Topical methadone compositions and methods for using the same
WO2007098114A3 (en) Clotting and healing compositions containing keratin biomaterials
CY1108992T1 (el) Η χρηση του υαλουρονικου οξεος για την παρασκευη συνθεσεων για τη θεραπευτικη αντιμετωπιση υποτροπιαζουσων αφθων της στοματικης κοιλοτητας
WO2006087759A3 (en) Pharmaceutical composition comprising curcumin and resveratrol and uses thereof in medical field
IL192181A0 (en) Use of benzo-fused heterocycle sulfamide derivatives for the treatment of mania and bipolar disorder
CY1109351T1 (el) Φαρμακευτικες συνθεσεις που περιεχουν διαμινοοξειδαση
AU2002214389A1 (en) Pharmaceutical composition containing honey for the treatment of wounds
WO2006037606A3 (en) Wound dressing compositions, especially for delivery of protease inhibitors
PL1962815T3 (pl) Zastosowanie błonotwórczych polimerów do pielęgnacji włosów z grupy poluretanów i zawierające te polimery preparaty i plastry farmaceutyczne
BRPI0408299A (pt) inibidores de catepsina s
NZ519722A (en) Treatment of diabetic ulcers
ECSP056186A (es) Composición farmacéutica en forma de hidrogel para administración transdérmica de sustancias activas
HUE009867T2 (pl)
WO2005077402A1 (en) Honey based gel formulations
WO2006026604A3 (en) Methods for promoting wound healing
AR015362A1 (es) Uso de una composicion topicamente activa para la manufactura de un medicamento util para el tratamiento de acne vulgaris y/o para producir efectos anti-envejecimiento
WO2006007846A3 (en) A dressing comprising a serine protease inhibitor and an antioxidant
Rocasalbas Lozano Development of multifunctional biopolymeric materials for teatment of decubitus ulcers
AU2006272424A8 (en) Homogemcitabines
WO2006075932A3 (en) Remedy to accelerate healing of wound and burn