PL1901783T3 - Kwas gentyzynowy do stabilizowania środków radiofarmaceutycznych 123-i - Google Patents

Kwas gentyzynowy do stabilizowania środków radiofarmaceutycznych 123-i

Info

Publication number
PL1901783T3
PL1901783T3 PL06726619T PL06726619T PL1901783T3 PL 1901783 T3 PL1901783 T3 PL 1901783T3 PL 06726619 T PL06726619 T PL 06726619T PL 06726619 T PL06726619 T PL 06726619T PL 1901783 T3 PL1901783 T3 PL 1901783T3
Authority
PL
Poland
Prior art keywords
radiopharmaceutical agents
stabilizing
gentic acid
gentic
acid
Prior art date
Application number
PL06726619T
Other languages
English (en)
Inventor
Ton Janssen
Den Bos Jan Van
Original Assignee
Ge Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Ltd filed Critical Ge Healthcare Ltd
Publication of PL1901783T3 publication Critical patent/PL1901783T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0446—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0446—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K51/0448—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil tropane or nortropane groups, e.g. cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0468—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K51/047—Benzodiazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/121—Solutions, i.e. homogeneous liquid formulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
PL06726619T 2005-07-11 2006-03-31 Kwas gentyzynowy do stabilizowania środków radiofarmaceutycznych 123-i PL1901783T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0514087.6A GB0514087D0 (en) 2005-07-11 2005-07-11 Stabilised radiopharmaceutical compositions
EP06726619.7A EP1901783B1 (en) 2005-07-11 2006-03-31 Gentisic acid for stabilising 123-i radiopharmaceuticals
PCT/GB2006/001215 WO2007007021A1 (en) 2005-07-11 2006-03-31 Gentisic acid for stabilisig 123-i radiopharmaceuticals

Publications (1)

Publication Number Publication Date
PL1901783T3 true PL1901783T3 (pl) 2015-03-31

Family

ID=34896966

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06726619T PL1901783T3 (pl) 2005-07-11 2006-03-31 Kwas gentyzynowy do stabilizowania środków radiofarmaceutycznych 123-i

Country Status (10)

Country Link
US (1) US8188296B2 (pl)
EP (1) EP1901783B1 (pl)
JP (1) JP5341512B2 (pl)
CN (1) CN101257929B (pl)
DK (1) DK1901783T3 (pl)
ES (1) ES2527531T3 (pl)
GB (1) GB0514087D0 (pl)
PL (1) PL1901783T3 (pl)
PT (1) PT1901783E (pl)
WO (1) WO2007007021A1 (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2277897A1 (en) 2001-04-16 2011-01-26 Wyeth Holdings Corporation Streptococcus pneumoniae open reading frames encoding polypeptide antigens and uses thereof
MX2010005122A (es) * 2007-11-07 2010-08-18 Ge Healthcare Bv Estabilizacion de radiofarmaceuticos.
KR20160030589A (ko) 2009-04-15 2016-03-18 랜티우스 메디컬 이메징, 인크. 아스코르브산을 사용한 방사성 약제 조성물의 안정화
KR101915821B1 (ko) * 2010-03-23 2018-11-06 지이 헬스케어 에이에스 안정화된 ｘ―선 진단용 조성물의 제조
WO2011147762A2 (en) 2010-05-25 2011-12-01 Bayer Pharma Aktiengesellschaft Stabilized radiopharmaceutical composition
US20120264949A1 (en) * 2011-04-13 2012-10-18 Atomic Energy Council-Institute Of Nuclear Energy Research Method of Labeling Dopamine D2 Receptor Using Radiosynthesized Ligand of Iodine-123-Epidepride
US10048254B2 (en) * 2013-06-04 2018-08-14 Albany Medical College Cyclic-di-AMP specific detection
AU2015335599B2 (en) 2014-10-24 2020-03-19 Molecular Insight Pharmaceuticals, Inc. Preparations of meta-iodobenzylguanidine and precursors thereof
WO2017155937A1 (en) 2016-03-07 2017-09-14 Actinium Pharmaceuticals, Inc. Stabilized radiolabeled anti-cd45 immunoglobulin compositions
JP6837895B2 (ja) * 2017-04-04 2021-03-03 日本化薬株式会社 医薬品溶液製剤の製造方法
US11351276B2 (en) * 2018-06-22 2022-06-07 Jubilant Draximage Inc. Radiopharmaceutical compositions of radioactive halogenated benzylguanidine
CN114423421A (zh) * 2019-05-24 2022-04-29 透明医药有限公司 Psma显像剂的制剂
JP7773990B2 (ja) * 2020-10-22 2025-11-20 日本メジフィジックス株式会社 放射性ジルコニウム錯体の製造方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4233284A (en) * 1978-03-31 1980-11-11 The Procter & Gamble Company Stabilized radiographic scanning agents
US4497744A (en) * 1978-03-31 1985-02-05 Mallinckrodt, Inc. Gentisic acid salts as radiographic scanning agent stabilizers
BE899739A (nl) * 1984-05-24 1984-11-26 Univ Bruxelles Werkwijze voor het controleren van de substitutie op aromatische kern,en, werkwijze en apparatuur ter bereiding van samenstelling voor scintigrafisch onderzoek.
US4942231A (en) * 1984-05-24 1990-07-17 Mallinckrodt, Inc. Method of preparing a chlorinated, brominated, radio-brominated, iodinated and/or radioiodinated aromatic or heteroaromatic compound
US5306482A (en) 1991-04-09 1994-04-26 Merck Frosst Canada, Inc. Radiopharmaceutical bacteriostats
DK0600992T3 (da) * 1991-08-29 2000-10-09 Mallinckrodt Medical Inc Anvendelse af gentissyre eller gentisylalkohol til stabilisering af radiomærkede peptider og proteiner
US5314678A (en) * 1992-01-28 1994-05-24 Mallinckrodt Medical, Inc. Sodium iodide 131 I capsules
US6315979B1 (en) * 1998-06-02 2001-11-13 The Dow Chemical Company Radioiodinated sulfonated phenols for brachytherapy
CA2413538A1 (en) * 2000-07-06 2002-01-17 Bristol-Myers Squibb Pharma Company Stable radiopharmaceutical compositions and methods for preparation thereof
GB0031592D0 (en) * 2000-12-28 2001-02-07 Nycomed Amersham Plc Stabilised radiopharmaceutical compositions
JP5139678B2 (ja) 2003-07-24 2013-02-06 ブラッコ・イメージング・ソシエタ・ペル・アチオニ 安定な放射性医薬品組成物およびその製法

Also Published As

Publication number Publication date
CN101257929B (zh) 2012-05-23
JP2009500441A (ja) 2009-01-08
JP5341512B2 (ja) 2013-11-13
DK1901783T3 (en) 2015-01-19
PT1901783E (pt) 2015-02-05
EP1901783B1 (en) 2014-11-05
ES2527531T3 (es) 2015-01-26
GB0514087D0 (en) 2005-08-17
US8188296B2 (en) 2012-05-29
WO2007007021A1 (en) 2007-01-18
CN101257929A (zh) 2008-09-03
EP1901783A1 (en) 2008-03-26
US20090005595A1 (en) 2009-01-01

Similar Documents

Publication Publication Date Title
LTC1912503I2 (lt) Fungicidiniai mišiniai, turintys 1-metilpirazol-4-ilo karboksirūgšties anilidus
DK3385253T3 (da) Kontrastmidler til myocardial perfusionsbilleddannelse
ATE431152T1 (de) Verbesserte ophthamologische bimatoprost-lösung
HUS1400051I1 (hu) Lurazidont tartalmazó gyógyászati készítmény
DK1856042T3 (da) Substituerede gamma-lactamer som terapeutiske midler
ITBO20050123A1 (it) Formulazioni farmaceutiche gastroresistenti contenenti rifaximina
CY2013047I2 (el) Ενωσεις διαρυλυδαντοϊνης
DK1876897T3 (da) Aktivstofkombinationer
DE602006007875D1 (de) Kapseln
DE502005005266D1 (de) Dosierpumpe
DK1737304T3 (da) Flydende koncentreret formel
DE502006002890D1 (de) Fungizide wirkstoffkombination
PL2278284T3 (pl) Zestaw ważący
EP1897558A4 (en) SOLID PREPARATION
ATE443056T1 (de) Substituierte n-sulfonylaminophenylethyl-2- phenoxyacetamidverbindungen
PL1901783T3 (pl) Kwas gentyzynowy do stabilizowania środków radiofarmaceutycznych 123-i
DE602006020744D1 (de) Fertigspritze
ITMI20042238A1 (it) Composti per fluoropolirterei
ATE431137T1 (de) Fexofenadinlösungsformulierung
FI20050284A0 (fi) Sekoitin
EP1853274A4 (en) 2-METHYLENE-19-NOR- (20S-24S) - 1ALPHA, 25-D HYDROXYVITAMINE-D2
ITMI20052509A1 (it) Assemblati per dispositivi elettrochimici
DE602007010931D1 (de) Säurefarbstoffe
DE602006006692D1 (de) Konzentrierte flüssige triazolfungizidformulierungen
NL1031705A1 (nl) Aminozuurderivaten.