PL1926472T3 - Stabilizowane i konserwowane kompozycje oftalmologiczne zawierające ketotifen - Google Patents

Stabilizowane i konserwowane kompozycje oftalmologiczne zawierające ketotifen

Info

Publication number: PL1926472T3
Authority: PL; Poland
Prior art keywords: ophthalmic compositions; stabilized; hydrogen peroxide; preserved; ketotifen ophthalmic
Prior art date: 2005-08-26

Application number

PL06802303T

Other languages

English (en)

Inventor

Fu-Pao Tsao

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-08-26

Filing date

2006-08-24

Publication date

2011-09-30

2006-08-24 Application filed by Novartis Ag filed Critical Novartis Ag

2011-09-30 Publication of PL1926472T3 publication Critical patent/PL1926472T3/pl

Links

239000000203 mixture Substances 0.000 title abstract 3
ZCVMWBYGMWKGHF-UHFFFAOYSA-N Ketotifene Chemical compound C1CN(C)CCC1=C1C2=CC=CC=C2CC(=O)C2=C1C=CS2 ZCVMWBYGMWKGHF-UHFFFAOYSA-N 0.000 title abstract 2
229960004958 ketotifen Drugs 0.000 title abstract 2
MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 6
206010010744 Conjunctivitis allergic Diseases 0.000 abstract 1
208000002205 allergic conjunctivitis Diseases 0.000 abstract 1
208000024998 atopic conjunctivitis Diseases 0.000 abstract 1
235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1
239000003381 stabilizer Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Ophthalmology & Optometry (AREA)
Inorganic Chemistry (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

PL06802303T 2005-08-26 2006-08-24 Stabilizowane i konserwowane kompozycje oftalmologiczne zawierające ketotifen PL1926472T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US11/212,957 US20070048388A1 (en)	2005-08-26	2005-08-26	Stabilized and preserved ketotifen ophthalmic compositions
PCT/US2006/033163 WO2007025094A2 (en)	2005-08-26	2006-08-24	Stabilized and preserved ketotifen ophthalmic compositions
EP06802303A EP1926472B1 (en)	2005-08-26	2006-08-24	Stabilized and preserved ketotifen ophthalmic compositions

Publications (1)

Publication Number	Publication Date
PL1926472T3 true PL1926472T3 (pl)	2011-09-30

Family

ID=37670685

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL06802303T PL1926472T3 (pl)	2005-08-26	2006-08-24	Stabilizowane i konserwowane kompozycje oftalmologiczne zawierające ketotifen

Country Status (19)

Country	Link
US (4)	US20070048388A1 (pl)
EP (1)	EP1926472B1 (pl)
JP (1)	JP5172678B2 (pl)
KR (1)	KR20080042143A (pl)
CN (1)	CN101252908B (pl)
AT (1)	ATE505182T1 (pl)
AU (2)	AU2006282980A1 (pl)
BR (1)	BRPI0615384B8 (pl)
CA (1)	CA2619834C (pl)
CY (1)	CY1111678T1 (pl)
DE (1)	DE602006021321D1 (pl)
DK (1)	DK1926472T3 (pl)
ES (1)	ES2363988T3 (pl)
MX (1)	MX2008002653A (pl)
PL (1)	PL1926472T3 (pl)
PT (1)	PT1926472E (pl)
RU (1)	RU2442583C2 (pl)
SI (1)	SI1926472T1 (pl)
WO (1)	WO2007025094A2 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20070208058A1 (en) *	2004-10-25	2007-09-06	Bryant Roy W	Stable Pharmaceutical Compositions and Methods of Making and Using Same
US20070048389A1 (en) *	2005-08-26	2007-03-01	Fu-Pao Tsao	Stabilized and preserved ketotifen ophthalmic compositions
US20090220618A1 (en) *	2008-02-29	2009-09-03	Erning Xia	Pharmaceutical formulations comprising polyanionic materials and source of hydrogen peroxide
WO2010107525A1 (en) *	2009-03-17	2010-09-23	Aciex Therapeutics, Inc.	Ophthalmic formulations of ketotifen and methods of use
CN110024781A (zh) *	2019-05-23	2019-07-19	昆明野水生物科技有限公司	一种在常温下能迅速杀灭芽孢的制剂及其应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4614646A (en) *	1984-12-24	1986-09-30	The Dow Chemical Company	Stabilization of peroxide systems in the presence of alkaline earth metal ions
US4819617A (en) *	1986-09-04	1989-04-11	University Of Florida	Viscoelastic material for ophthalmic surgery
US5607698A (en) *	1988-08-04	1997-03-04	Ciba-Geigy Corporation	Method of preserving ophthalmic solution and compositions therefor
SG64856A1 (en) *	1988-08-04	1999-05-25	Novartis Ag	A method of preserving ophthalimic solutions and composition thereof
US5019591A (en) *	1989-02-17	1991-05-28	Pennsylvania Research Corporation	Method for treating retinopathy and other small vessel disorders associated with diabetes
US5958957A (en) *	1996-04-19	1999-09-28	Novo Nordisk A/S	Modulators of molecules with phosphotyrosine recognition units
EP0938896A1 (en) *	1998-01-15	1999-09-01	Novartis AG	Autoclavable pharmaceutical compositions containing a chelating agent
AU6416999A (en) *	1998-10-08	2000-04-26	Hampar L. Karagoezian	Synergistic antimicrobial, dermatological and ophthalmic preparations containingchlorite and hydrogen peroxide
GB9824160D0 (en) *	1998-11-04	1998-12-30	Darwin Discovery Ltd	Heterocyclic compounds and their therapeutic use
RU2266115C2 (ru) *	1999-09-13	2005-12-20	Бридж Фарма, Инк.	Оптически активные изомеры кетотифена и их терапевтически активные метаболиты
US6531128B1 (en) *	2000-02-08	2003-03-11	Pharmacia Corporation	Methods for treating glaucoma
DE60125026T2 (de) *	2000-03-23	2007-06-28	Takeda Pharmaceutical Co. Ltd.	Fluorisochinolinderivate, verfahren zu ihrer herstellung und ihre anwendung
TWI236377B (en) *	2000-09-28	2005-07-21	Novartis Ag	Stabilized hydrogen peroxide solutions
RU2193403C1 (ru) *	2001-05-23	2002-11-27	Московский научно-исследовательский институт глазных болезней им. Гельмгольца	Глазные капли для лечения аллергических конъюнктивитов и кератоконъюнктивитов
AR034372A1 (es) *	2001-06-08	2004-02-18	Novartis Ag	Composiciones farmaceuticas
AR038299A1 (es) *	2002-01-18	2005-01-12	Novartis Ag	Metodos para conservar soluciones oftalmicas y soluciones oftalmicas conservadas.
JP2004143157A (ja) *	2002-10-01	2004-05-20	Taisho Pharmaceut Co Ltd	点眼剤
US20050244509A1 (en) *	2004-03-17	2005-11-03	Fu-Pao Tsao	Ophthalmic solutions

2005
- 2005-08-26 US US11/212,957 patent/US20070048388A1/en not_active Abandoned
2006
- 2006-08-24 KR KR1020087007222A patent/KR20080042143A/ko not_active Ceased
- 2006-08-24 AT AT06802303T patent/ATE505182T1/de active
- 2006-08-24 CA CA2619834A patent/CA2619834C/en active Active
- 2006-08-24 RU RU2008111067/15A patent/RU2442583C2/ru not_active IP Right Cessation
- 2006-08-24 BR BRPI0615384A patent/BRPI0615384B8/pt active IP Right Grant
- 2006-08-24 DE DE602006021321T patent/DE602006021321D1/de active Active
- 2006-08-24 WO PCT/US2006/033163 patent/WO2007025094A2/en not_active Ceased
- 2006-08-24 CN CN200680031237XA patent/CN101252908B/zh not_active Expired - Fee Related
- 2006-08-24 JP JP2008528166A patent/JP5172678B2/ja not_active Expired - Fee Related
- 2006-08-24 PL PL06802303T patent/PL1926472T3/pl unknown
- 2006-08-24 AU AU2006282980A patent/AU2006282980A1/en not_active Abandoned
- 2006-08-24 PT PT06802303T patent/PT1926472E/pt unknown
- 2006-08-24 ES ES06802303T patent/ES2363988T3/es active Active
- 2006-08-24 DK DK06802303.5T patent/DK1926472T3/da active
- 2006-08-24 MX MX2008002653A patent/MX2008002653A/es active IP Right Grant
- 2006-08-24 EP EP06802303A patent/EP1926472B1/en active Active
- 2006-08-24 SI SI200631024T patent/SI1926472T1/sl unknown
2008
- 2008-04-15 US US12/082,844 patent/US20080193558A1/en not_active Abandoned
2010
- 2010-11-03 AU AU2010241211A patent/AU2010241211B2/en not_active Ceased
2011
- 2011-06-28 CY CY20111100610T patent/CY1111678T1/el unknown
- 2011-12-20 US US13/330,992 patent/US20120095050A1/en not_active Abandoned
2012
- 2012-11-09 US US13/673,050 patent/US20130102634A1/en not_active Abandoned

Also Published As

Publication number	Publication date
JP5172678B2 (ja)	2013-03-27
RU2008111067A (ru)	2009-10-10
CA2619834A1 (en)	2007-03-01
DE602006021321D1 (de)	2011-05-26
EP1926472B1 (en)	2011-04-13
WO2007025094A2 (en)	2007-03-01
CA2619834C (en)	2014-05-06
KR20080042143A (ko)	2008-05-14
WO2007025094A3 (en)	2007-05-18
BRPI0615384A2 (pt)	2011-05-17
CY1111678T1 (el)	2015-10-07
US20130102634A1 (en)	2013-04-25
CN101252908B (zh)	2011-09-14
AU2010241211A1 (en)	2010-11-25
ATE505182T1 (de)	2011-04-15
US20070048388A1 (en)	2007-03-01
EP1926472A2 (en)	2008-06-04
BRPI0615384B1 (pt)	2019-06-18
US20120095050A1 (en)	2012-04-19
US20080193558A1 (en)	2008-08-14
RU2442583C2 (ru)	2012-02-20
SI1926472T1 (sl)	2011-07-29
CN101252908A (zh)	2008-08-27
PT1926472E (pt)	2011-07-11
MX2008002653A (es)	2008-03-18
JP2009506065A (ja)	2009-02-12
DK1926472T3 (da)	2011-07-18
AU2006282980A1 (en)	2007-03-01
AU2010241211B2 (en)	2012-12-20
ES2363988T3 (es)	2011-08-22
BRPI0615384B8 (pt)	2021-05-25

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