PL1940818T3 - Pochodne aminokwasów zawierające grupę disulfanylową jako mieszane inhibitory neprylizyny i aminopeptydazy n - Google Patents
Pochodne aminokwasów zawierające grupę disulfanylową jako mieszane inhibitory neprylizyny i aminopeptydazy nInfo
- Publication number
- PL1940818T3 PL1940818T3 PL06807506T PL06807506T PL1940818T3 PL 1940818 T3 PL1940818 T3 PL 1940818T3 PL 06807506 T PL06807506 T PL 06807506T PL 06807506 T PL06807506 T PL 06807506T PL 1940818 T3 PL1940818 T3 PL 1940818T3
- Authority
- PL
- Poland
- Prior art keywords
- disulfanyl
- aminopeptidase
- inhibitors
- mixed
- derivatives containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0510862A FR2892413B1 (fr) | 2005-10-25 | 2005-10-25 | Nouveaux derives d'amino-acides, leur procede de preparation et leur utilisation therapeutique |
| FR0604030A FR2892414B1 (fr) | 2005-10-25 | 2006-05-05 | Nouveaux derives d'amino-acides, leur procede de preparation et leur utilisation therapeutique |
| PCT/EP2006/067711 WO2007048787A1 (fr) | 2005-10-25 | 2006-10-24 | Derives d'amino-acides contenant un groupement disulfanyle comme inhibiteurs mixtes de la neprilysine et de l 'aminopeptidase n |
| EP06807506A EP1940818B1 (fr) | 2005-10-25 | 2006-10-24 | Derives d'amino-acides contenant un groupement disulfanyle comme inhibiteurs mixtes de la neprilysine et de l 'aminopeptidase n |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1940818T3 true PL1940818T3 (pl) | 2012-01-31 |
Family
ID=37491764
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL06807506T PL1940818T3 (pl) | 2005-10-25 | 2006-10-24 | Pochodne aminokwasów zawierające grupę disulfanylową jako mieszane inhibitory neprylizyny i aminopeptydazy n |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1940818B1 (pl) |
| AU (1) | AU2006307938B2 (pl) |
| PL (1) | PL1940818T3 (pl) |
| WO (1) | WO2007048787A1 (pl) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2931151A1 (fr) * | 2008-05-13 | 2009-11-20 | Pharmaleads Soc Par Actions Si | Nouveaux derives d'amino-acides, leur procede de preparation et leur utilisation therapeutique |
| US8993631B2 (en) | 2010-11-16 | 2015-03-31 | Novartis Ag | Method of treating contrast-induced nephropathy |
| US20150018566A1 (en) | 2011-08-25 | 2015-01-15 | The Provost, Fellows, Foundation Scholars, & the Other Members of Board, of The College of the Holy | Tubulin binding agents |
| FR2997081B1 (fr) | 2012-10-23 | 2015-11-27 | Pharmaleads | Inhibiteurs mixtes de l'aminopeptidase n et de la neprilysine |
| TWI712582B (zh) | 2015-10-14 | 2020-12-11 | 法商領先藥物公司 | 用來製備(5s,10s)-10-苄基-16-甲基-11,14,18-三側氧基-15,17,19-三氧雜-2,7,8-三噻基-12-氮二十一烷基-5-銨基(e)-3-羧基丙烯酸鹽的工業方法 |
| FR3077201B1 (fr) | 2018-01-26 | 2020-01-17 | Pharmaleads | Derives aminoacides contenant un groupement disulfanyle sous forme d'un inhibiteur de nep et d'apn pour la prevention et le traitement des douleurs relatives au nerf trijumeau |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2651229B1 (fr) * | 1989-08-24 | 1991-12-13 | Inst Nat Sante Rech Med | Nouveaux derives d'amino-acides, leur procede de preparation et leur application therapeutique. |
-
2006
- 2006-10-24 EP EP06807506A patent/EP1940818B1/fr active Active
- 2006-10-24 AU AU2006307938A patent/AU2006307938B2/en not_active Ceased
- 2006-10-24 PL PL06807506T patent/PL1940818T3/pl unknown
- 2006-10-24 WO PCT/EP2006/067711 patent/WO2007048787A1/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU2006307938B2 (en) | 2012-04-19 |
| AU2006307938A1 (en) | 2007-05-03 |
| EP1940818A1 (fr) | 2008-07-09 |
| EP1940818B1 (fr) | 2011-08-24 |
| WO2007048787A1 (fr) | 2007-05-03 |
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