PL2001556T3 - Związki tioniny i ich zastosowanie - Google Patents
Związki tioniny i ich zastosowanieInfo
- Publication number
- PL2001556T3 PL2001556T3 PL07712962T PL07712962T PL2001556T3 PL 2001556 T3 PL2001556 T3 PL 2001556T3 PL 07712962 T PL07712962 T PL 07712962T PL 07712962 T PL07712962 T PL 07712962T PL 2001556 T3 PL2001556 T3 PL 2001556T3
- Authority
- PL
- Poland
- Prior art keywords
- thioninium
- compounds
- thioninium compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78669906P | 2006-03-29 | 2006-03-29 | |
| EP07712962.5A EP2001556B1 (en) | 2006-03-29 | 2007-03-28 | Thioninium compounds and their use |
| PCT/GB2007/001107 WO2007110630A1 (en) | 2006-03-29 | 2007-03-28 | Thioninium compounds and their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2001556T3 true PL2001556T3 (pl) | 2015-03-31 |
Family
ID=38163667
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL14185157T PL2853293T3 (pl) | 2006-03-29 | 2007-03-28 | Związki tioniny i ich zastosowanie |
| PL07712962T PL2001556T3 (pl) | 2006-03-29 | 2007-03-28 | Związki tioniny i ich zastosowanie |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL14185157T PL2853293T3 (pl) | 2006-03-29 | 2007-03-28 | Związki tioniny i ich zastosowanie |
Country Status (13)
| Country | Link |
|---|---|
| EP (2) | EP2853293B1 (pl) |
| JP (1) | JP5184507B2 (pl) |
| CN (2) | CN103641794B (pl) |
| AU (1) | AU2007231127B2 (pl) |
| CA (1) | CA2645919C (pl) |
| DK (2) | DK2853293T3 (pl) |
| ES (2) | ES2525001T3 (pl) |
| HR (2) | HRP20141261T1 (pl) |
| MY (2) | MY162640A (pl) |
| PL (2) | PL2853293T3 (pl) |
| PT (2) | PT2001556E (pl) |
| SI (2) | SI2001556T1 (pl) |
| WO (1) | WO2007110630A1 (pl) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104119294B (zh) | 2006-03-29 | 2018-10-30 | 维斯塔实验室有限公司 | 3,7-二氨基-10h-吩噻嗪化合物的制备方法 |
| AU2008265045B2 (en) * | 2007-06-19 | 2014-02-27 | Taurx Therapeutics Management Ltd. | Phenothiazine compounds for treating Mild Cognitive Impairment |
| EP3689346B1 (en) | 2008-12-10 | 2024-01-24 | WisTa Laboratories Ltd. | 3,6-disubstituted xanthylium salts for treating tauopathies |
| US8828986B2 (en) | 2011-04-20 | 2014-09-09 | Prosetta Antiviral Inc. | Antiviral compounds |
| US8785434B2 (en) | 2010-04-30 | 2014-07-22 | Prosetta Antiviral Inc. | Antiviral compounds |
| KR101888713B1 (ko) | 2011-02-11 | 2018-08-14 | 위스타 레보레이토리스 리미티드 | 페노티아진 디아미늄 염 및 이의 용도 |
| CN102690244A (zh) * | 2011-03-22 | 2012-09-26 | 中国科学院上海生命科学研究院 | 调节α-突触核蛋白积聚的物质及其制药用途 |
| GB201317702D0 (en) * | 2013-10-07 | 2013-11-20 | Wista Lab Ltd | Methods of chemical synthesis of diaminophenothiazinium compounds including methylthioninium chloride (MTC) |
| GB201512678D0 (en) | 2015-07-20 | 2015-08-26 | Wista Lab Ltd | Methods of chemical synthesis |
| PL3487505T3 (pl) | 2016-07-25 | 2023-10-09 | Wista Laboratories Ltd. | Podawanie i dawkowanie diaminofenotiazyn |
| GB201614834D0 (en) * | 2016-09-01 | 2016-10-19 | Wista Lab Ltd | Treatment of dementia |
| GB201621817D0 (en) | 2016-12-21 | 2017-02-01 | Wista Lab Ltd | Methods of chemical synthesis |
| BR112021000802A2 (pt) | 2018-07-26 | 2021-04-13 | Wista Laboratories Ltd. | Dosagem otimizada de diaminofenotiazinas em populações |
| US12215234B2 (en) * | 2019-09-21 | 2025-02-04 | RK Pharma Solutions LLC | Process for the purification of methylene blue |
| GB202010652D0 (en) | 2020-07-10 | 2020-08-26 | Wista Lab Ltd | Anti-tau antibodies |
| CA3257856A1 (en) | 2022-05-31 | 2023-12-07 | Wista Laboratories Ltd. | TREATMENT OF NEURODEGENERATIVE DISORDERS USING COMPOUNDS CONTAINING METHYLTHIONINIUM (MT) |
| WO2024063700A1 (en) | 2022-09-21 | 2024-03-28 | Yin Sze Loh | Oral formulation of diaminophenothiazines and methods of making and using the same in the treatment and/or prevention of diseases |
| GB202500018D0 (en) | 2025-01-02 | 2025-02-19 | Wista Lab Ltd | Long term dosing of neurodegenerative disorders utilising methylthioninium (mt) containing compounds |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996004915A1 (en) * | 1994-08-08 | 1996-02-22 | Albert Einstein College Of Medicine Of Yeshiva University | Methods for treating and/or preventing alzheimer's disease using phenothiazines and/or thioxanthenes |
| GB9506197D0 (en) * | 1995-03-27 | 1995-05-17 | Hoffmann La Roche | Inhibition of tau-tau association. |
| JP2000344685A (ja) * | 1999-03-26 | 2000-12-12 | Bf Kenkyusho:Kk | アズールａ類似化合物によるアミロイドが蓄積する疾患の画像診断プローブおよびそれを含む画像診断用組成物 |
| GB0101049D0 (en) | 2001-01-15 | 2001-02-28 | Univ Aberdeen | Materials and methods relating to protein aggregation in neurodegenerative disease |
| GB0106953D0 (en) * | 2001-03-20 | 2001-05-09 | Univ Aberdeen | Neufofibrillary labels |
| GB0322756D0 (en) | 2003-09-29 | 2003-10-29 | Univ Aberdeen | Methods of chemical synthesis |
| BRPI0416928A (pt) * | 2003-11-28 | 2007-01-16 | Photopharmica Ltd | desenvolvimento de derivados biologicamente ativos de azul de metileno |
| JP5186212B2 (ja) * | 2004-09-23 | 2013-04-17 | ウィスタ ラボラトリーズ リミテッド | メチルチオニニウム塩化物（ｍｔｃ）などのジアミノフェノチアジニウム化合物を化学合成および精製する方法 |
| WO2006032879A2 (en) | 2004-09-23 | 2006-03-30 | Wista Laboratories Ltd. | Methods of chemical synthesis and purification of diaminophenothiazinium compounds including methylthioninium chloride (mtc) |
-
2007
- 2007-03-28 DK DK14185157.6T patent/DK2853293T3/en active
- 2007-03-28 PT PT77129625T patent/PT2001556E/pt unknown
- 2007-03-28 MY MYPI20083822A patent/MY162640A/en unknown
- 2007-03-28 ES ES07712962.5T patent/ES2525001T3/es active Active
- 2007-03-28 SI SI200731541T patent/SI2001556T1/sl unknown
- 2007-03-28 PT PT141851576T patent/PT2853293T/pt unknown
- 2007-03-28 CA CA2645919A patent/CA2645919C/en active Active
- 2007-03-28 JP JP2009502207A patent/JP5184507B2/ja active Active
- 2007-03-28 ES ES14185157.6T patent/ES2659030T3/es active Active
- 2007-03-28 SI SI200732008T patent/SI2853293T1/en unknown
- 2007-03-28 PL PL14185157T patent/PL2853293T3/pl unknown
- 2007-03-28 PL PL07712962T patent/PL2001556T3/pl unknown
- 2007-03-28 CN CN201310514618.5A patent/CN103641794B/zh active Active
- 2007-03-28 DK DK07712962.5T patent/DK2001556T3/da active
- 2007-03-28 EP EP14185157.6A patent/EP2853293B1/en active Active
- 2007-03-28 AU AU2007231127A patent/AU2007231127B2/en active Active
- 2007-03-28 EP EP07712962.5A patent/EP2001556B1/en active Active
- 2007-03-28 WO PCT/GB2007/001107 patent/WO2007110630A1/en not_active Ceased
- 2007-03-28 CN CN2007800202730A patent/CN101460222B/zh active Active
- 2007-03-28 HR HRP20141261TT patent/HRP20141261T1/hr unknown
- 2007-03-28 MY MYPI2014003327A patent/MY172157A/en unknown
-
2018
- 2018-02-02 HR HRP20180204TT patent/HRP20180204T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SI2001556T1 (sl) | 2014-12-31 |
| SI2853293T1 (en) | 2018-03-30 |
| EP2853293A1 (en) | 2015-04-01 |
| CN101460222A (zh) | 2009-06-17 |
| CA2645919C (en) | 2016-05-31 |
| AU2007231127A1 (en) | 2007-10-04 |
| PL2853293T3 (pl) | 2018-05-30 |
| CN101460222B (zh) | 2013-12-04 |
| MY172157A (en) | 2019-11-15 |
| DK2001556T3 (da) | 2014-11-10 |
| AU2007231127B2 (en) | 2013-03-14 |
| HRP20141261T1 (xx) | 2015-03-13 |
| MY162640A (en) | 2017-06-30 |
| CN103641794A (zh) | 2014-03-19 |
| ES2525001T3 (es) | 2014-12-16 |
| WO2007110630A1 (en) | 2007-10-04 |
| EP2853293B1 (en) | 2017-11-22 |
| EP2001556B1 (en) | 2014-10-01 |
| PT2853293T (pt) | 2018-02-13 |
| CA2645919A1 (en) | 2007-10-04 |
| DK2853293T3 (en) | 2018-01-22 |
| HK1121084A1 (en) | 2009-04-17 |
| PT2001556E (pt) | 2014-12-09 |
| HK1208000A1 (en) | 2016-02-19 |
| JP5184507B2 (ja) | 2013-04-17 |
| HRP20180204T1 (hr) | 2018-03-09 |
| CN103641794B (zh) | 2016-09-21 |
| JP2009531405A (ja) | 2009-09-03 |
| ES2659030T3 (es) | 2018-03-13 |
| EP2001556A1 (en) | 2008-12-17 |
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