PL2027137T3 - Oczyszczanie imino- i aminocukrów - Google Patents

Oczyszczanie imino- i aminocukrów

Info

Publication number
PL2027137T3
PL2027137T3 PL06772888T PL06772888T PL2027137T3 PL 2027137 T3 PL2027137 T3 PL 2027137T3 PL 06772888 T PL06772888 T PL 06772888T PL 06772888 T PL06772888 T PL 06772888T PL 2027137 T3 PL2027137 T3 PL 2027137T3
Authority
PL
Poland
Prior art keywords
imino
amino sugar
sugar purification
purification
amino
Prior art date
Application number
PL06772888T
Other languages
English (en)
Inventor
Michael Major
Robert Peterson
Szymon Kosinski
Original Assignee
Amicus Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amicus Therapeutics Inc filed Critical Amicus Therapeutics Inc
Publication of PL2027137T3 publication Critical patent/PL2027137T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL06772888T 2005-06-08 2006-06-08 Oczyszczanie imino- i aminocukrów PL2027137T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68913005P 2005-06-08 2005-06-08
EP06772888.1A EP2027137B1 (en) 2005-06-08 2006-06-08 Imino and amino sugar purification
PCT/US2006/022756 WO2008045015A1 (en) 2005-06-08 2006-06-08 Imino and amino sugar purification

Publications (1)

Publication Number Publication Date
PL2027137T3 true PL2027137T3 (pl) 2015-08-31

Family

ID=41256089

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06772888T PL2027137T3 (pl) 2005-06-08 2006-06-08 Oczyszczanie imino- i aminocukrów

Country Status (12)

Country Link
US (1) US7973157B2 (pl)
EP (1) EP2027137B1 (pl)
JP (1) JP5107350B2 (pl)
CN (1) CN101277969B (pl)
BR (1) BRPI0613222A2 (pl)
DK (1) DK2027137T3 (pl)
ES (1) ES2537089T3 (pl)
IL (1) IL187988A (pl)
PL (1) PL2027137T3 (pl)
PT (1) PT2027137E (pl)
SI (1) SI2027137T1 (pl)
WO (1) WO2008045015A1 (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX351004B (es) 2006-05-16 2017-09-26 Nat Institutes Of Health Ensayos para diagnosticar y evaluar opciones de tratamiento para enfermedad de fabry.
WO2009102895A2 (en) 2008-02-12 2009-08-20 Amicus Therapeutics, Inc. Method to predict response to pharmacological chaperone treatment of diseases
CN103626809B (zh) * 2013-12-10 2016-01-20 安徽丰原发酵技术工程研究有限公司 一种氨基葡萄糖盐酸盐母液的纯化方法
CN106687596A (zh) * 2014-02-17 2017-05-17 葛兰素史密斯克莱知识产权发展有限公司 微生物学方法
AU2018277756A1 (en) 2017-05-30 2020-01-23 Amicus Therapeutics, Inc. Methods of treating fabry patients having renal impairment
IT201700078102A1 (it) * 2017-07-11 2019-01-11 Dipharma Francis Srl Sintesi di un azazucchero e suoi intermedi
EP4717319A3 (en) 2018-02-06 2026-06-10 Amicus Therapeutics, Inc. Methods of treating fabry disease in pregnant patients
LT3840753T (lt) 2018-08-20 2024-11-11 Amicus Therapeutics, Inc. Migalastatas skirtas naudoti fabry ligos gydymo būdui, pacientams turintiems gla geno mutaciją
KR20220044560A (ko) 2019-08-07 2022-04-08 아미쿠스 세라퓨틱스, 인코포레이티드 Gla 유전자에 돌연변이를 갖는 환자에서 파브리 질병을 치료하는 방법
US11623916B2 (en) 2020-12-16 2023-04-11 Amicus Therapeutics, Inc. Highly purified batches of pharmaceutical grade migalastat and methods of producing the same
WO2022132992A1 (en) * 2020-12-16 2022-06-23 Amicus Therapeutics, Inc. Highly purified batches of pharmaceutical grade 1-deoxygalactonojirimycin compounds
CN112500441A (zh) * 2020-12-20 2021-03-16 上海彩迩文生化科技有限公司 一种高纯度糖基磷酸盐的制备工艺

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US2801261A (en) * 1954-05-28 1957-07-30 Du Pont Alkyl esters of substituted thiocyanooctanoic acids
NO154918C (no) * 1977-08-27 1987-01-14 Bayer Ag Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.
US4634765A (en) 1984-12-18 1987-01-06 Merrell Dow Pharmaceuticals Inc. Homodisaccharide hypoglycemic agents
US5192772A (en) * 1987-12-09 1993-03-09 Nippon Shinyaku Co. Ltd. Therapeutic agents
US5250545A (en) 1988-02-12 1993-10-05 Meiji Seika Kaisha, Ltd. Cancer cell metastasis inhibitor methods
EP0344383A1 (en) * 1988-06-02 1989-12-06 Merrell Dow Pharmaceuticals Inc. Novel alpha-Glucosidase inhibitors
US5003072A (en) * 1988-11-03 1991-03-26 G. D. Searle & Co. 1,5-dideoxy-1,5-imino-D-glucitol derivatives
US5144037A (en) * 1988-11-03 1992-09-01 G. D. Searle & Co. 1,5-dideoxy-1,5-imino-d-glucitol derivatives
US4957926A (en) 1988-12-22 1990-09-18 Monsanto Company Method of treating herpesviruses
US5043273A (en) 1989-08-17 1991-08-27 Monsanto Company Phosphorylated glycosidase inhibitor prodrugs
KR910007655A (ko) * 1989-10-03 1991-05-30 엠. 피. 잭슨 치료용 뉴클레오시드
DE3936295A1 (de) * 1989-11-01 1991-05-02 Bayer Ag Verfahren zur herstellung von zwischenprodukten und zur synthese von n-(2-hydroxyethyl)-2-hydroxymethyl-3,4,5-trihydroxypiperidine
IT1236902B (it) * 1989-12-20 1993-04-26 Dispositivo di comando per aghi a pistone in macchine a crochet
US5200523A (en) * 1990-10-10 1993-04-06 Monsanto Company Synthesis of nojirimycin derivatives
US5273981A (en) * 1990-10-18 1993-12-28 Monsanto Company Intramolecular carbamate derivative of 2,3-Di-O-blocked-1,4-dideoxy-4-fluoro-nojirimycins
US5248779A (en) * 1991-06-17 1993-09-28 Monsanto Company Synthesis of nojirimycin derivatives
US5206251A (en) * 1992-04-01 1993-04-27 G. D. Searle & Co. 2- and 3- amino and azido derivatives of 1,5-iminosugars
US5268482A (en) * 1992-04-01 1993-12-07 G. D. Searle & Co. 2- and 3-sulfur derivatives of 1,5-iminosugars
US5258518A (en) * 1992-04-01 1993-11-02 G. D. Searle & Co. 2-substituted tertiary carbinol derivatives of deoxynojirimycin
JP2921544B2 (ja) * 1993-07-30 1999-07-19 三菱瓦斯化学株式会社 モノアルケニルベンゼン類の精製法
AU1876095A (en) * 1994-02-25 1995-09-11 G.D. Searle & Co. Use of 1-deoxynojirimycin and its derivatives for treating mammals infected with respiratory syncytial virus
US5451679A (en) * 1994-03-08 1995-09-19 G. D. Searle & Co. 2-chloro and 2-bromo derivatives of 1,5-iminosugars
FR2764304B1 (fr) 1997-06-06 1999-07-16 Rhone Poulenc Rorer Sa Nouvelle classe d'agents transfectants cationiques des acides nucleiques
EA004705B1 (ru) * 1998-02-12 2004-06-24 Дж.Д.Серл Энд Ко. Применение n-замещенных 1,5-дидезокси-1,5-имино-d-глюцитных производных для лечения инфекций, вызываемых вирусами гепатита
DE60037664T2 (de) 1999-08-10 2008-12-24 The Chancellor, Masters And Scholars Of The University Of Oxford Langkettige n-alkyl verbindungen und deren oxa-derivate zur verwendung als anitvirale mittel
US6620921B1 (en) * 1999-11-16 2003-09-16 Industrial Research Limited Glucofuranoses
KR100446483B1 (ko) 2000-03-31 2004-09-01 미시간 스테이트 유니버시티 옥심 또는 이민으로부터 1,5-디데옥시-1,5-이미노 헥시톨제조방법
JP2002087808A (ja) * 2000-09-14 2002-03-27 Showa Denko Kk パーフルオロカーボンの精製用吸着剤、その製造方法、高純度オクタフルオロシクロブタン、その精製方法及び製造方法並びにその用途
NZ520108A (en) * 2002-07-10 2004-09-24 Ind Res Ltd Process for preparing kifunensine (cyclic oxamide derivative of 1-amino-mannojirimycin) intermediate and kifunensine therefrom

Also Published As

Publication number Publication date
US20060293515A1 (en) 2006-12-28
DK2027137T3 (en) 2015-05-18
IL187988A (en) 2014-11-30
WO2008045015A8 (en) 2009-11-05
HK1125111A1 (en) 2009-07-31
EP2027137A1 (en) 2009-02-25
IL187988A0 (en) 2009-02-11
SI2027137T1 (sl) 2015-06-30
WO2008045015A1 (en) 2008-04-17
CN101277969B (zh) 2012-12-19
EP2027137A4 (en) 2010-04-14
JP2009539834A (ja) 2009-11-19
PT2027137E (pt) 2015-06-09
US7973157B2 (en) 2011-07-05
JP5107350B2 (ja) 2012-12-26
ES2537089T3 (es) 2015-06-02
EP2027137B1 (en) 2015-02-18
CN101277969A (zh) 2008-10-01
BRPI0613222A2 (pt) 2010-12-28

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