PL2027137T3 - Oczyszczanie imino- i aminocukrów - Google Patents

Oczyszczanie imino- i aminocukrów

Info

Publication number
PL2027137T3
PL2027137T3 PL06772888T PL06772888T PL2027137T3 PL 2027137 T3 PL2027137 T3 PL 2027137T3 PL 06772888 T PL06772888 T PL 06772888T PL 06772888 T PL06772888 T PL 06772888T PL 2027137 T3 PL2027137 T3 PL 2027137T3
Authority
PL
Poland
Prior art keywords
imino
amino sugar
sugar purification
purification
amino
Prior art date
Application number
PL06772888T
Other languages
English (en)
Inventor
Michael Major
Robert Peterson
Szymon Kosinski
Original Assignee
Amicus Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amicus Therapeutics Inc filed Critical Amicus Therapeutics Inc
Publication of PL2027137T3 publication Critical patent/PL2027137T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL06772888T 2005-06-08 2006-06-08 Oczyszczanie imino- i aminocukrów PL2027137T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68913005P 2005-06-08 2005-06-08
EP06772888.1A EP2027137B1 (en) 2005-06-08 2006-06-08 Imino and amino sugar purification
PCT/US2006/022756 WO2008045015A1 (en) 2005-06-08 2006-06-08 Imino and amino sugar purification

Publications (1)

Publication Number Publication Date
PL2027137T3 true PL2027137T3 (pl) 2015-08-31

Family

ID=41256089

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06772888T PL2027137T3 (pl) 2005-06-08 2006-06-08 Oczyszczanie imino- i aminocukrów

Country Status (12)

Country Link
US (1) US7973157B2 (pl)
EP (1) EP2027137B1 (pl)
JP (1) JP5107350B2 (pl)
CN (1) CN101277969B (pl)
BR (1) BRPI0613222A2 (pl)
DK (1) DK2027137T3 (pl)
ES (1) ES2537089T3 (pl)
IL (1) IL187988A (pl)
PL (1) PL2027137T3 (pl)
PT (1) PT2027137E (pl)
SI (1) SI2027137T1 (pl)
WO (1) WO2008045015A1 (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2573498T3 (es) 2006-05-16 2016-06-08 Amicus Therapeutics, Inc. Opciones de tratamiento para la enfermedad de Fabry
SI3470077T1 (sl) 2008-02-12 2020-12-31 Amicus Therapeutics, Inc. Postopek za napovedovanje odgovora na zdravljenje bolezni s farmakološkim spremljevalcem
CN103626809B (zh) * 2013-12-10 2016-01-20 安徽丰原发酵技术工程研究有限公司 一种氨基葡萄糖盐酸盐母液的纯化方法
WO2015121488A1 (en) * 2014-02-17 2015-08-20 Glaxosmithkline Intellectual Property Development Limited Microbiological process
CA3224537C (en) 2017-05-30 2025-09-09 Amicus Therapeutics, Inc. USE OF MIGALASTAT IN THE TREATMENT OF PATIENTS WITH FABRY DISEASE AND RENAL FAILURE
IT201700078102A1 (it) * 2017-07-11 2019-01-11 Dipharma Francis Srl Sintesi di un azazucchero e suoi intermedi
CA3090496C (en) 2018-02-06 2024-03-26 Amicus Therapeutics, Inc. Use of migalastat for treating fabry disease in pregnant patients
EP4282472A3 (en) 2018-08-20 2024-02-21 Amicus Therapeutics, Inc. Methods of treating fabry disease in patients having a mutation in the gla gene
EP3851105B1 (en) 2019-08-07 2026-03-04 Amicus Therapeutics, Inc. Migalastat for use in treating fabry disease in patients having a mutation in the gla gene
WO2022132992A1 (en) * 2020-12-16 2022-06-23 Amicus Therapeutics, Inc. Highly purified batches of pharmaceutical grade 1-deoxygalactonojirimycin compounds
US11623916B2 (en) * 2020-12-16 2023-04-11 Amicus Therapeutics, Inc. Highly purified batches of pharmaceutical grade migalastat and methods of producing the same
CN112500441A (zh) * 2020-12-20 2021-03-16 上海彩迩文生化科技有限公司 一种高纯度糖基磷酸盐的制备工艺

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US2801261A (en) * 1954-05-28 1957-07-30 Du Pont Alkyl esters of substituted thiocyanooctanoic acids
NO154918C (no) 1977-08-27 1987-01-14 Bayer Ag Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.
US4634765A (en) 1984-12-18 1987-01-06 Merrell Dow Pharmaceuticals Inc. Homodisaccharide hypoglycemic agents
US5192772A (en) 1987-12-09 1993-03-09 Nippon Shinyaku Co. Ltd. Therapeutic agents
US5250545A (en) 1988-02-12 1993-10-05 Meiji Seika Kaisha, Ltd. Cancer cell metastasis inhibitor methods
EP0344383A1 (en) * 1988-06-02 1989-12-06 Merrell Dow Pharmaceuticals Inc. Novel alpha-Glucosidase inhibitors
US5003072A (en) 1988-11-03 1991-03-26 G. D. Searle & Co. 1,5-dideoxy-1,5-imino-D-glucitol derivatives
US5144037A (en) 1988-11-03 1992-09-01 G. D. Searle & Co. 1,5-dideoxy-1,5-imino-d-glucitol derivatives
US4957926A (en) 1988-12-22 1990-09-18 Monsanto Company Method of treating herpesviruses
US5043273A (en) 1989-08-17 1991-08-27 Monsanto Company Phosphorylated glycosidase inhibitor prodrugs
KR910007655A (ko) 1989-10-03 1991-05-30 엠. 피. 잭슨 치료용 뉴클레오시드
DE3936295A1 (de) 1989-11-01 1991-05-02 Bayer Ag Verfahren zur herstellung von zwischenprodukten und zur synthese von n-(2-hydroxyethyl)-2-hydroxymethyl-3,4,5-trihydroxypiperidine
IT1236902B (it) * 1989-12-20 1993-04-26 Dispositivo di comando per aghi a pistone in macchine a crochet
US5200523A (en) 1990-10-10 1993-04-06 Monsanto Company Synthesis of nojirimycin derivatives
US5273981A (en) 1990-10-18 1993-12-28 Monsanto Company Intramolecular carbamate derivative of 2,3-Di-O-blocked-1,4-dideoxy-4-fluoro-nojirimycins
US5248779A (en) 1991-06-17 1993-09-28 Monsanto Company Synthesis of nojirimycin derivatives
US5268482A (en) 1992-04-01 1993-12-07 G. D. Searle & Co. 2- and 3-sulfur derivatives of 1,5-iminosugars
US5258518A (en) 1992-04-01 1993-11-02 G. D. Searle & Co. 2-substituted tertiary carbinol derivatives of deoxynojirimycin
US5206251A (en) 1992-04-01 1993-04-27 G. D. Searle & Co. 2- and 3- amino and azido derivatives of 1,5-iminosugars
JP2921544B2 (ja) * 1993-07-30 1999-07-19 三菱瓦斯化学株式会社 モノアルケニルベンゼン類の精製法
WO1995022975A1 (en) * 1994-02-25 1995-08-31 G.D. Searle & Co. Use of 1-deoxynojirimycin and its derivatives for treating mammals infected with respiratory syncytial virus
US5451679A (en) 1994-03-08 1995-09-19 G. D. Searle & Co. 2-chloro and 2-bromo derivatives of 1,5-iminosugars
FR2764304B1 (fr) 1997-06-06 1999-07-16 Rhone Poulenc Rorer Sa Nouvelle classe d'agents transfectants cationiques des acides nucleiques
US6809083B1 (en) 1998-02-12 2004-10-26 Richard A. Mueller Use of N-substituted-1, 5-dideoxy-1, 5-imino-D-glucitol compounds for treating hepatitis virus infections
AU1840101A (en) 1999-08-10 2001-03-05 Chancellor, Masters And Scholars Of The University Of Oxford, The Long chain n-alkyl compounds and oxo-derivatives thereof
AU1901801A (en) 1999-11-16 2001-05-30 Industrial Research Limited Glucofuranoses
JP4060079B2 (ja) 2000-03-31 2008-03-12 ミシガン ステイト ユニバーシティー オキシム又はイミンからの１，５―ジデオキシ―１，５−イミノヘキシトールの製法
JP2002087808A (ja) * 2000-09-14 2002-03-27 Showa Denko Kk パーフルオロカーボンの精製用吸着剤、その製造方法、高純度オクタフルオロシクロブタン、その精製方法及び製造方法並びにその用途
NZ520108A (en) * 2002-07-10 2004-09-24 Ind Res Ltd Process for preparing kifunensine (cyclic oxamide derivative of 1-amino-mannojirimycin) intermediate and kifunensine therefrom

Also Published As

Publication number Publication date
DK2027137T3 (en) 2015-05-18
SI2027137T1 (sl) 2015-06-30
JP5107350B2 (ja) 2012-12-26
IL187988A0 (en) 2009-02-11
CN101277969A (zh) 2008-10-01
EP2027137A4 (en) 2010-04-14
JP2009539834A (ja) 2009-11-19
ES2537089T3 (es) 2015-06-02
WO2008045015A8 (en) 2009-11-05
HK1125111A1 (en) 2009-07-31
EP2027137A1 (en) 2009-02-25
EP2027137B1 (en) 2015-02-18
WO2008045015A1 (en) 2008-04-17
BRPI0613222A2 (pt) 2010-12-28
CN101277969B (zh) 2012-12-19
US7973157B2 (en) 2011-07-05
PT2027137E (pt) 2015-06-09
US20060293515A1 (en) 2006-12-28
IL187988A (en) 2014-11-30

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