PL203030A1 - METHOD OF MAKING NEW ACYL DERIVATIVES OF HELLEBRIGENIN - Google Patents

METHOD OF MAKING NEW ACYL DERIVATIVES OF HELLEBRIGENIN

Info

Publication number: PL203030A1
Authority: PL; Poland
Prior art keywords: hellebrigenin; acyl derivatives; making new; new acyl; making
Prior art date: 1976-12-17

Application number

PL20303077A

Other languages

Polish (pl)

Other versions

PL110178B1 (en

Original Assignee

Degussa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-12-17

Filing date

1977-12-16

Publication date

1979-03-26

1977-12-16 Application filed by Degussa filed Critical Degussa

1979-03-26 Publication of PL203030A1 publication Critical patent/PL203030A1/en

1980-07-31 Publication of PL110178B1 publication Critical patent/PL110178B1/en

Links

TVKPTWJPKVSGJB-XHCIOXAKSA-N (3s,5s,8r,9s,10s,13r,14s,17r)-3,5,14-trihydroxy-13-methyl-17-(6-oxopyran-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthrene-10-carbaldehyde Chemical class C=1([C@H]2CC[C@]3(O)[C@H]4[C@@H]([C@]5(CC[C@H](O)C[C@@]5(O)CC4)C=O)CC[C@@]32C)C=CC(=O)OC=1 TVKPTWJPKVSGJB-XHCIOXAKSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J19/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 by a lactone ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives

Landscapes

Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Heart & Thoracic Surgery (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Hospice & Palliative Care (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Steroid Compounds (AREA)
Hydrogenated Pyridines (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Plural Heterocyclic Compounds (AREA)

PL1977203030A 1976-12-17 1977-12-16 Method of producing new acyl derivatives of hellebrigenine PL110178B1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB52759/76A GB1577633A (en)	1976-12-17	1976-12-17	Acyl derivatives of hellebrigenin

Publications (2)

Publication Number	Publication Date
PL203030A1 true PL203030A1 (en)	1979-03-26
PL110178B1 PL110178B1 (en)	1980-07-31

Family

ID=10465185

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL1977203030A PL110178B1 (en)	1976-12-17	1977-12-16	Method of producing new acyl derivatives of hellebrigenine

Country Status (15)

Country	Link
JP (1)	JPS591279B2 (en)
AT (1)	AT372391B (en)
BE (1)	BE861968A (en)
CH (1)	CH639107A5 (en)
DD (1)	DD133151A5 (en)
DE (1)	DE2755122C2 (en)
ES (2)	ES465135A1 (en)
FI (1)	FI58135C (en)
FR (1)	FR2374336A1 (en)
GB (1)	GB1577633A (en)
HU (1)	HU176767B (en)
IT (1)	IT1113251B (en)
PL (1)	PL110178B1 (en)
SU (2)	SU751328A3 (en)
ZA (1)	ZA777494B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS61158784U (en) *	1985-03-25	1986-10-01
EP1108702A1 (en) *	1999-12-13	2001-06-20	Kvaerner Process Technology Limited	Process for the co-production of aliphatic diols and cyclic ethers
WO2010102673A1 (en) *	2009-03-13	2010-09-16	Unibioscreen S.A.	Hellebrin and hellebrigenin derivatives
JP5815675B2 (en) *	2010-04-27	2015-11-17	ファルマ、マール、ソシエダード、アノニマＰｈａｒｍａＭｒｓ，Ｓ．Ａ．	Unsaturated anticancer steroidal lactone at position 7 (8)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1901484A1 (en) *	1969-01-14	1970-10-29	Hoechst Ag	Cardiac active oxyesters of steroid cardenolides and steroid bufandienolides and processes for their preparation

1976
- 1976-12-17 GB GB52759/76A patent/GB1577633A/en not_active Expired
1977
- 1977-12-10 DE DE2755122A patent/DE2755122C2/en not_active Expired
- 1977-12-13 IT IT52184/77A patent/IT1113251B/en active
- 1977-12-15 SU SU772553849A patent/SU751328A3/en active
- 1977-12-15 ZA ZA00777494A patent/ZA777494B/en unknown
- 1977-12-15 FR FR7737795A patent/FR2374336A1/en active Granted
- 1977-12-16 AT AT0903877A patent/AT372391B/en not_active IP Right Cessation
- 1977-12-16 DD DD7700202719A patent/DD133151A5/en unknown
- 1977-12-16 HU HU77DE947A patent/HU176767B/en unknown
- 1977-12-16 PL PL1977203030A patent/PL110178B1/en not_active IP Right Cessation
- 1977-12-16 ES ES465135A patent/ES465135A1/en not_active Expired
- 1977-12-16 JP JP52152295A patent/JPS591279B2/en not_active Expired
- 1977-12-16 FI FI773814A patent/FI58135C/en not_active IP Right Cessation
- 1977-12-16 BE BE6046270A patent/BE861968A/en not_active IP Right Cessation
- 1977-12-16 ES ES465136A patent/ES465136A1/en not_active Expired
1978
- 1978-01-01 CH CH1554377A patent/CH639107A5/en not_active IP Right Cessation
- 1978-12-25 SU SU782701599A patent/SU795487A3/en active

Also Published As

Publication number	Publication date
FI773814A7 (en)	1978-06-18
GB1577633A (en)	1980-10-29
ATA903877A (en)	1983-02-15
SU795487A3 (en)	1981-01-07
AT372391B (en)	1983-09-26
FI58135B (en)	1980-08-29
DE2755122C2 (en)	1983-06-30
ES465136A1 (en)	1979-01-01
CH639107A5 (en)	1983-10-31
IT1113251B (en)	1986-01-20
ES465135A1 (en)	1978-10-01
ZA777494B (en)	1979-02-28
DD133151A5 (en)	1978-12-13
JPS591279B2 (en)	1984-01-11
FR2374336A1 (en)	1978-07-13
JPS5395956A (en)	1978-08-22
HU176767B (en)	1981-05-28
FI58135C (en)	1980-12-10
FR2374336B1 (en)	1980-11-07
DE2755122A1 (en)	1978-06-22
PL110178B1 (en)	1980-07-31
SU751328A3 (en)	1980-07-23
BE861968A (en)	1978-06-16

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Legal Events

Date	Code	Title	Description
2010-08-31	LAPS	Decisions on the lapse of the protection rights	Effective date: 20050130