PL2084543T3 - Stratyfikacja ryzyka ostrego zespołu wieńcowego za pomocą fragmentów/ częściowych peptydów prowazopresyny, a zwłaszcza kopeptyny lub neurofizyny II - Google Patents
Stratyfikacja ryzyka ostrego zespołu wieńcowego za pomocą fragmentów/ częściowych peptydów prowazopresyny, a zwłaszcza kopeptyny lub neurofizyny IIInfo
- Publication number
- PL2084543T3 PL2084543T3 PL07846265T PL07846265T PL2084543T3 PL 2084543 T3 PL2084543 T3 PL 2084543T3 PL 07846265 T PL07846265 T PL 07846265T PL 07846265 T PL07846265 T PL 07846265T PL 2084543 T3 PL2084543 T3 PL 2084543T3
- Authority
- PL
- Poland
- Prior art keywords
- provasopressin
- neurophysin
- fragments
- acute coronary
- coronary syndrome
- Prior art date
Links
- 208000004476 Acute Coronary Syndrome Diseases 0.000 title 1
- 102400000060 Copeptin Human genes 0.000 title 1
- 101800000115 Copeptin Proteins 0.000 title 1
- 102000002710 Neurophysins Human genes 0.000 title 1
- 108010018674 Neurophysins Proteins 0.000 title 1
- 239000012634 fragment Substances 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 238000013517 stratification Methods 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2410/00—Assays, e.g. immunoassays or enzyme assays, involving peptides of less than 20 animo acids
- G01N2410/04—Oxytocins; Vasopressins; Related peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/324—Coronary artery diseases, e.g. angina pectoris, myocardial infarction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE200610050497 DE102006050497A1 (de) | 2006-10-26 | 2006-10-26 | Risikostratifizierung des akuten Koronarsyndroms mittels Fragmenten / Teilpeptiden des proVasopressins, insbesondere Copeptin oder Neurophysin II |
| DE200610057409 DE102006057409A1 (de) | 2006-12-04 | 2006-12-04 | Risikostratifizierung des akuten Koronarsyndroms mittels Fragmenten / Teilpeptiden des proVasopressins, insbesondere Copeptin oder Neurophysin II |
| PCT/DE2007/001928 WO2008049422A2 (de) | 2006-10-26 | 2007-10-26 | Risikostratifizierung des akuten koronarsyndroms mittels fragmenten / teilpeptiden des provasopressins, insbesondere copeptin oder neurophysin ii |
| EP07846265.2A EP2084543B1 (de) | 2006-10-26 | 2007-10-26 | Risikostratifizierung des akuten koronarsyndroms mittels fragmenten / teilpeptiden des provasopressins, insbesondere copeptin oder neurophysin ii |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2084543T3 true PL2084543T3 (pl) | 2018-04-30 |
Family
ID=39276269
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL07846265T PL2084543T3 (pl) | 2006-10-26 | 2007-10-26 | Stratyfikacja ryzyka ostrego zespołu wieńcowego za pomocą fragmentów/ częściowych peptydów prowazopresyny, a zwłaszcza kopeptyny lub neurofizyny II |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US8501485B2 (pl) |
| EP (1) | EP2084543B1 (pl) |
| JP (2) | JP5320294B2 (pl) |
| DE (1) | DE112007003185A5 (pl) |
| DK (1) | DK2084543T3 (pl) |
| ES (1) | ES2652027T3 (pl) |
| PL (1) | PL2084543T3 (pl) |
| WO (1) | WO2008049422A2 (pl) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140046407A1 (en) * | 2001-08-31 | 2014-02-13 | Bio Control Medical (B.C.M.) Ltd. | Nerve stimulation techniques |
| EP1628136A1 (en) * | 2004-08-19 | 2006-02-22 | B.R.A.H.M.S. Aktiengesellschaft | Method of diagnosis of disease using copeptin |
| ATE473448T1 (de) * | 2006-04-24 | 2010-07-15 | Univ Wien Med | Verfahren zur diagnose von herz-kreislauf- krankheiten |
| EP2084543B1 (de) * | 2006-10-26 | 2017-10-18 | B.R.A.H.M.S GmbH | Risikostratifizierung des akuten koronarsyndroms mittels fragmenten / teilpeptiden des provasopressins, insbesondere copeptin oder neurophysin ii |
| DE102006058266A1 (de) * | 2006-12-08 | 2008-06-12 | Brahms Aktiengesellschaft | Diagnose und Risikostratifizierung von Herzinsuffizienz mittels Neurophysin |
| DE102007009751A1 (de) | 2007-02-28 | 2008-09-04 | B.R.A.H.M.S Aktiengesellschaft | Verfahren zur selektiven Bestimmung von Procalcitonin 1-116 für diagnostische Zwecke sowie Antikörper und Kits zur Durchführung eines solchen Verfahrens |
| CN102257386B (zh) * | 2008-10-24 | 2014-12-31 | B.R.A.H.M.S有限公司 | 通过测定标志肽的水平在已患过中风或短暂性缺血性发作的患者中进行预后和风险评估 |
| EP2356463B1 (en) * | 2008-10-31 | 2017-08-30 | B.R.A.H.M.S GmbH | Arginine vasopressin pro-hormone as predictive biomarker for diabetes |
| JP5753159B2 (ja) * | 2009-05-05 | 2015-07-22 | ベー．エル．アー．ハー．エム．エス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 内皮性機能／機能不全に関連した疾患に罹患している患者の血管作動性ホルモンに基づいた層化 |
| EP2635904A1 (en) * | 2010-11-01 | 2013-09-11 | B.R.A.H.M.S GmbH | Prognosis and risk assessment of patients with non-specific complaints |
| EP2533052A1 (en) * | 2011-06-07 | 2012-12-12 | B.R.A.H.M.S GmbH | Diagnostic use of proSomatostatin |
| CN103917638A (zh) * | 2011-09-08 | 2014-07-09 | Nexusdx股份有限公司 | 多级分析物检定 |
| KR20180101595A (ko) | 2016-02-01 | 2018-09-12 | 프리벤치오 인코포레이티드 | 심혈관 질환 및 사건을 위한 진단학적 및 예후적 방법 |
| US12400762B2 (en) | 2018-12-11 | 2025-08-26 | Eko.Ai Pte. Ltd. | Automatic clinical workflow that recognizes and analyzes 2D and doppler modality echocardiogram images for automated cardiac measurements and diagnosis of cardiac amyloidosis and hypertrophic cardiomyopathy |
| US11446009B2 (en) | 2018-12-11 | 2022-09-20 | Eko.Ai Pte. Ltd. | Clinical workflow to diagnose heart disease based on cardiac biomarker measurements and AI recognition of 2D and doppler modality echocardiogram images |
| US12001939B2 (en) | 2018-12-11 | 2024-06-04 | Eko.Ai Pte. Ltd. | Artificial intelligence (AI)-based guidance for an ultrasound device to improve capture of echo image views |
| US12322100B2 (en) | 2018-12-11 | 2025-06-03 | Eko.Ai Pte. Ltd. | Automatic clinical workflow that recognizes and analyzes 2D and doppler modality echocardiogram images for automated cardiac measurements and grading of aortic stenosis severity |
| US11931207B2 (en) | 2018-12-11 | 2024-03-19 | Eko.Ai Pte. Ltd. | Artificial intelligence (AI) recognition of echocardiogram images to enhance a mobile ultrasound device |
| KR102318236B1 (ko) * | 2020-02-18 | 2021-10-26 | 한림대학교 산학협력단 | 혈중 코펩틴의 농도를 이용한 지연성 뇌허혈 진단 방법 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9305142D0 (en) * | 1993-03-12 | 1993-04-28 | Medinnova Sf | Method |
| EP1322957B1 (en) | 2001-05-04 | 2009-08-12 | Biosite Incorporated | Diagnostic markers of acute coronary syndromes and methods of use thereof |
| MXPA03004105A (es) * | 2002-05-14 | 2004-10-15 | Hoffmann La Roche | Elaboracion de una prognosis en casos de enfermedad cardiaca usando una combinacion de marcadores. |
| CA2492475A1 (en) * | 2002-07-16 | 2004-01-22 | Woomera Therapeutics, Inc. | Compositions and uses thereof for identifying and targeting provasopressin-expressing cancer cells |
| CA2485722A1 (en) * | 2003-10-22 | 2005-04-22 | Paul Lehmann | Soluble transferrin receptor |
| EP1530047A1 (en) * | 2003-11-07 | 2005-05-11 | Roche Diagnostics GmbH | Proximal markers of arterial thrombosis and inflammation for risk stratification of coronary heart disease |
| EP1628136A1 (en) * | 2004-08-19 | 2006-02-22 | B.R.A.H.M.S. Aktiengesellschaft | Method of diagnosis of disease using copeptin |
| DE102004051847B4 (de) * | 2004-10-25 | 2008-09-18 | Dade Behring Marburg Gmbh | Verhältnis von PIGF und Flt-1 als prognostischer Parameter bei kardio-vaskulären Erkrankungen |
| US20080057590A1 (en) * | 2006-06-07 | 2008-03-06 | Mickey Urdea | Markers associated with arteriovascular events and methods of use thereof |
| EP2084543B1 (de) * | 2006-10-26 | 2017-10-18 | B.R.A.H.M.S GmbH | Risikostratifizierung des akuten koronarsyndroms mittels fragmenten / teilpeptiden des provasopressins, insbesondere copeptin oder neurophysin ii |
| DE102006053442A1 (de) * | 2006-11-12 | 2008-05-15 | Brahms Aktiengesellschaft | Diagnose und Risikostratifizierung von Infektionen und chronischen Erkrankungen der Atemwege und Lunge mittels proVasopressin, insbesondere Copeptin oder Neurophysin II |
| DE102006058266A1 (de) * | 2006-12-08 | 2008-06-12 | Brahms Aktiengesellschaft | Diagnose und Risikostratifizierung von Herzinsuffizienz mittels Neurophysin |
| DE102007021443A1 (de) * | 2007-05-08 | 2008-11-13 | Brahms Aktiengesellschaft | Diagnose und Risikostratifizierung mittels NT-proET-1 |
| EP2148203A1 (en) * | 2008-07-23 | 2010-01-27 | BRAHMS Aktiengesellschaft | Azurophilic granule proteases as markers in cardiological diseases |
| CN102257386B (zh) * | 2008-10-24 | 2014-12-31 | B.R.A.H.M.S有限公司 | 通过测定标志肽的水平在已患过中风或短暂性缺血性发作的患者中进行预后和风险评估 |
-
2007
- 2007-10-26 EP EP07846265.2A patent/EP2084543B1/de active Active
- 2007-10-26 DK DK07846265.2T patent/DK2084543T3/en active
- 2007-10-26 PL PL07846265T patent/PL2084543T3/pl unknown
- 2007-10-26 WO PCT/DE2007/001928 patent/WO2008049422A2/de not_active Ceased
- 2007-10-26 ES ES07846265.2T patent/ES2652027T3/es active Active
- 2007-10-26 US US12/447,105 patent/US8501485B2/en active Active
- 2007-10-26 DE DE112007003185T patent/DE112007003185A5/de not_active Withdrawn
- 2007-10-26 JP JP2009533659A patent/JP5320294B2/ja active Active
-
2013
- 2013-04-03 JP JP2013077587A patent/JP2013178249A/ja active Pending
- 2013-07-25 US US13/951,084 patent/US9261517B2/en active Active
-
2016
- 2016-01-21 US US15/003,734 patent/US10254289B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20100028921A1 (en) | 2010-02-04 |
| JP2013178249A (ja) | 2013-09-09 |
| ES2652027T3 (es) | 2018-01-31 |
| JP5320294B2 (ja) | 2013-10-23 |
| JP2010507786A (ja) | 2010-03-11 |
| DK2084543T3 (en) | 2018-01-22 |
| US20130344513A1 (en) | 2013-12-26 |
| US8501485B2 (en) | 2013-08-06 |
| HK1137808A1 (en) | 2010-08-06 |
| US10254289B2 (en) | 2019-04-09 |
| WO2008049422A2 (de) | 2008-05-02 |
| US20160131660A1 (en) | 2016-05-12 |
| EP2084543A2 (de) | 2009-08-05 |
| DE112007003185A5 (de) | 2009-10-01 |
| EP2084543B1 (de) | 2017-10-18 |
| US9261517B2 (en) | 2016-02-16 |
| WO2008049422A3 (de) | 2009-01-15 |
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