PL2089374T3 - Sposób syntezy N-[3-[(2-metoksyfenylo)sulfanylo]-2-metylopropylo]-3,4dihydro-2H-1,5-benzoksatiepino-3-aminy - Google Patents

Sposób syntezy N-[3-[(2-metoksyfenylo)sulfanylo]-2-metylopropylo]-3,4dihydro-2H-1,5-benzoksatiepino-3-aminy

Info

Publication number
PL2089374T3
PL2089374T3 PL07870250T PL07870250T PL2089374T3 PL 2089374 T3 PL2089374 T3 PL 2089374T3 PL 07870250 T PL07870250 T PL 07870250T PL 07870250 T PL07870250 T PL 07870250T PL 2089374 T3 PL2089374 T3 PL 2089374T3
Authority
PL
Poland
Prior art keywords
benzoxathiepin
sulfanyl
methylpropyl
methoxyphenyl
dihydro
Prior art date
Application number
PL07870250T
Other languages
English (en)
Inventor
Bernard Vacher
Yves Brunel
Jean-Louis Maurel
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pf Medicament filed Critical Pf Medicament
Publication of PL2089374T3 publication Critical patent/PL2089374T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/18—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/20—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
PL07870250T 2006-11-08 2007-11-06 Sposób syntezy N-[3-[(2-metoksyfenylo)sulfanylo]-2-metylopropylo]-3,4dihydro-2H-1,5-benzoksatiepino-3-aminy PL2089374T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0609815A FR2908132B1 (fr) 2006-11-08 2006-11-08 Procede de synthese du n-[3-[(2-methoxyphenyl)sulfanyl]-2- methylpropyl]-3,4-dihydro-2h-1,5-benzoxathiepin-3-amine
EP07870250A EP2089374B1 (fr) 2006-11-08 2007-11-06 Procede de synthese du n- [3- [ (2-methoxyphenyl) sulfanyl] -2- methylpropyl] -3,4-dihydro-2h-1,5-benzoxathiepin-3-amine
PCT/FR2007/001831 WO2008068403A2 (fr) 2006-11-08 2007-11-06 Procede de synthese du n- [3- [ (2-methoxyphenyl) sulfanyl] -2- methylpropyl] -3,4-dihydro-2h-1,5-benzoxathiepin-3-amine

Publications (1)

Publication Number Publication Date
PL2089374T3 true PL2089374T3 (pl) 2011-01-31

Family

ID=38066470

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07870250T PL2089374T3 (pl) 2006-11-08 2007-11-06 Sposób syntezy N-[3-[(2-metoksyfenylo)sulfanylo]-2-metylopropylo]-3,4dihydro-2H-1,5-benzoksatiepino-3-aminy

Country Status (26)

Country Link
US (1) US7982054B2 (pl)
EP (1) EP2089374B1 (pl)
JP (1) JP5180965B2 (pl)
KR (1) KR101390486B1 (pl)
CN (1) CN101535287B (pl)
AR (1) AR063592A1 (pl)
AT (1) ATE476429T1 (pl)
AU (1) AU2007330711B2 (pl)
BR (1) BRPI0718702A2 (pl)
CA (1) CA2668951C (pl)
DE (1) DE602007008284D1 (pl)
ES (1) ES2350324T3 (pl)
FR (1) FR2908132B1 (pl)
IL (1) IL198528A (pl)
MA (1) MA30800B1 (pl)
MX (1) MX2009003957A (pl)
NO (1) NO20091980L (pl)
NZ (1) NZ576442A (pl)
PL (1) PL2089374T3 (pl)
PT (1) PT2089374E (pl)
RU (1) RU2414464C9 (pl)
TN (1) TN2009000176A1 (pl)
TW (1) TWI397527B (pl)
UA (1) UA94632C2 (pl)
WO (1) WO2008068403A2 (pl)
ZA (1) ZA200902732B (pl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2979823B1 (fr) * 2011-09-13 2013-09-27 Pf Medicament Utilisation du 3-(r)-[3-(2-methoxyphenylthio)-2-(s)-methyl-propyl]amino-3,4-dihydro-2h-1,5-benzoxathiepine pour le traitement du cancer et en particulier pour la prevention et/ou le traitement des metastases cancereuses

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985002617A1 (fr) * 1983-12-14 1985-06-20 Takeda Chemical Industries. Ltd. Derives de 1,5-benzoxathiepine et leur procede de preparation
FR2868779B1 (fr) * 2004-04-09 2008-08-22 Pierre Fabre Medicament Sa Procede de synthese et intermediaires de benzoxathiepines

Also Published As

Publication number Publication date
BRPI0718702A2 (pt) 2014-01-07
IL198528A (en) 2012-12-31
PT2089374E (pt) 2010-11-04
FR2908132B1 (fr) 2008-12-19
MX2009003957A (es) 2009-04-28
CA2668951C (fr) 2012-06-26
WO2008068403A2 (fr) 2008-06-12
TW200835688A (en) 2008-09-01
MA30800B1 (fr) 2009-10-01
US7982054B2 (en) 2011-07-19
RU2414464C9 (ru) 2011-11-10
CN101535287B (zh) 2013-02-27
RU2414464C2 (ru) 2011-03-20
FR2908132A1 (fr) 2008-05-09
JP5180965B2 (ja) 2013-04-10
ZA200902732B (en) 2010-02-24
CA2668951A1 (fr) 2008-06-12
HK1131970A1 (en) 2010-02-12
KR20090082463A (ko) 2009-07-30
AU2007330711A1 (en) 2008-06-12
AR063592A1 (es) 2009-02-04
ATE476429T1 (de) 2010-08-15
CN101535287A (zh) 2009-09-16
AU2007330711B2 (en) 2011-11-03
US20090318709A1 (en) 2009-12-24
IL198528A0 (en) 2010-02-17
NZ576442A (en) 2012-03-30
TWI397527B (zh) 2013-06-01
EP2089374B1 (fr) 2010-08-04
NO20091980L (no) 2009-06-08
WO2008068403A3 (fr) 2008-11-27
KR101390486B1 (ko) 2014-05-19
ES2350324T3 (es) 2011-01-21
TN2009000176A1 (fr) 2010-10-18
DE602007008284D1 (de) 2010-09-16
UA94632C2 (en) 2011-05-25
RU2009121560A (ru) 2010-12-20
JP2010509296A (ja) 2010-03-25
EP2089374A2 (fr) 2009-08-19

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