PL2114406T3 - Pochodne tioksantenowe jako środki przeciw-infekcyjne do zastosowania w leczeniu chorób zakaźnych - Google Patents

Pochodne tioksantenowe jako środki przeciw-infekcyjne do zastosowania w leczeniu chorób zakaźnych

Info

Publication number
PL2114406T3
PL2114406T3 PL08700129T PL08700129T PL2114406T3 PL 2114406 T3 PL2114406 T3 PL 2114406T3 PL 08700129 T PL08700129 T PL 08700129T PL 08700129 T PL08700129 T PL 08700129T PL 2114406 T3 PL2114406 T3 PL 2114406T3
Authority
PL
Poland
Prior art keywords
treatment
infective agents
infectious diseases
thioxanthene
derivates
Prior art date
Application number
PL08700129T
Other languages
English (en)
Inventor
Birgit Kjælgaard Giwercman
Original Assignee
Bkg Pharma Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bkg Pharma Aps filed Critical Bkg Pharma Aps
Publication of PL2114406T3 publication Critical patent/PL2114406T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Dairy Products (AREA)
PL08700129T 2007-01-05 2008-01-07 Pochodne tioksantenowe jako środki przeciw-infekcyjne do zastosowania w leczeniu chorób zakaźnych PL2114406T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/DK2007/000006 WO2008080398A1 (en) 2007-01-05 2007-01-05 Anti - infective agents such as phenothiazine and thioxanthene derivates to treat infectious diseases
PCT/DK2008/000005 WO2008080408A1 (en) 2007-01-05 2008-01-07 Thioxanthene derivates usefulto treat infectious diseases
EP08700129A EP2114406B1 (en) 2007-01-05 2008-01-07 Thioxanthene derivates as sole anti-infective agents for use in the treatment of infectious diseases

Publications (1)

Publication Number Publication Date
PL2114406T3 true PL2114406T3 (pl) 2011-10-31

Family

ID=37914358

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08700129T PL2114406T3 (pl) 2007-01-05 2008-01-07 Pochodne tioksantenowe jako środki przeciw-infekcyjne do zastosowania w leczeniu chorób zakaźnych

Country Status (17)

Country Link
US (1) US20100113430A1 (pl)
EP (2) EP2301545A1 (pl)
JP (2) JP5399921B2 (pl)
CN (1) CN101594869B (pl)
AT (1) ATE510540T1 (pl)
AU (1) AU2008203743B2 (pl)
CA (1) CA2673809C (pl)
CY (1) CY1111778T1 (pl)
DK (1) DK2114406T3 (pl)
EA (1) EA016886B1 (pl)
ES (1) ES2367151T3 (pl)
HR (1) HRP20110607T1 (pl)
MX (1) MX2009007235A (pl)
NZ (1) NZ577821A (pl)
PL (1) PL2114406T3 (pl)
PT (1) PT2114406E (pl)
WO (2) WO2008080398A1 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008080398A1 (en) * 2007-01-05 2008-07-10 Bkg Pharma Aps Anti - infective agents such as phenothiazine and thioxanthene derivates to treat infectious diseases
EP2246349A1 (en) 2009-04-20 2010-11-03 BKG Pharma ApS Treatment of infectious diseases
CN103172591B (zh) * 2013-03-13 2014-07-30 陕西科技大学 含吩噻嗪基的Schiff碱类化合物及其制备方法和应用
CN103709122B (zh) * 2013-11-29 2016-05-25 四川大学 用于治疗的抗肿瘤和抗真菌化合物
RU2019101646A (ru) * 2016-06-23 2020-07-23 Биоимикс Аб Противоинфекционные гетероциклические соединения и варианты их применения
CN112353805A (zh) * 2020-11-17 2021-02-12 北京化工大学 氟哌噻吨在治疗和预防柯萨奇病毒感染中的应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE578983A (pl) 1958-05-29
DE1210890B (de) 1960-03-07 1966-02-17 Smith & Kline & French Lab Verfahren zur Herstellung von Trifluormethyl-xanthen- oder thioxanthenderivaten
GB1453828A (en) * 1972-12-08 1976-10-27 Kefalas As Fluoro-substituted thiaxanthene derivatives
US4407800A (en) * 1981-11-02 1983-10-04 University Of Virginia Alumni Patents Foundation Protozoacidal activity of phenothiazines
AU625071B2 (en) * 1988-04-20 1992-07-02 Merrell Dow Pharmaceuticals Inc. N-alkylamino derivatives of aromatic, tricyclic compounds in the treatment of drug-resistant protozoal infections
US20020151543A1 (en) * 1998-05-28 2002-10-17 Sepracor Inc. Compositions and methods employing R (-) fluoxetine and other active ingredients
FR2813792B1 (fr) * 2000-09-12 2003-03-14 Inst Necker Moyens pour la regulation des defenses immunitaires
US6569853B1 (en) 2000-11-06 2003-05-27 Combinatorx, Incorporated Combinations of chlorpromazine and pentamidine for the treatment of neoplastic disorders
BR0210867A (pt) 2001-07-06 2004-06-29 Lifecycle Pharma As Processo para a preparação de um material particulado, métodos para aglomeração controlada de um material sólido finamente disperso, para melhorar a biodisponibilidade de uma substância terapêutica e/ou profilaticamente ativa, e para melhorar a vida em prateleira de uma composição farmacêutica, material articulado, composição farmacêutica, uso de um veìculo, material particulado farmacêutico, e, uso de aluminossilicato de magnésio e/ou de aluminometassilicato de magnésio
WO2003062388A2 (en) * 2002-01-16 2003-07-31 The Regents Of The University Of California Inhibition of rna function
US20060193788A1 (en) * 2002-11-26 2006-08-31 Hale Ron L Acute treatment of headache with phenothiazine antipsychotics
AU2003205543A1 (en) 2003-01-14 2004-08-10 Lifecycle Pharma A/S Dry dispersions
DE602004026071D1 (de) * 2003-08-13 2010-04-29 Kudos Pharm Ltd Aminopyrone und ihre verwendung als atm inhibitoren
MXPA06012566A (es) * 2004-04-30 2007-05-09 Bkg Pharma Aps Tratamiento de enfermedades infecciosas.
WO2006094207A2 (en) * 2005-03-03 2006-09-08 St. Jude Children's Research Hospital Substituted phenoxazines and acridones as inhibitors of akt
WO2008080398A1 (en) * 2007-01-05 2008-07-10 Bkg Pharma Aps Anti - infective agents such as phenothiazine and thioxanthene derivates to treat infectious diseases
EP2246349A1 (en) * 2009-04-20 2010-11-03 BKG Pharma ApS Treatment of infectious diseases

Also Published As

Publication number Publication date
ES2367151T3 (es) 2011-10-28
AU2008203743B2 (en) 2012-07-12
HRP20110607T1 (hr) 2011-09-30
WO2008080408A1 (en) 2008-07-10
CA2673809A1 (en) 2008-07-10
DK2114406T3 (da) 2011-09-12
NZ577821A (en) 2012-07-27
JP5399921B2 (ja) 2014-01-29
JP2013173752A (ja) 2013-09-05
US20100113430A1 (en) 2010-05-06
MX2009007235A (es) 2009-10-16
WO2008080398A1 (en) 2008-07-10
ATE510540T1 (de) 2011-06-15
EA200970663A1 (ru) 2009-12-30
EP2114406A1 (en) 2009-11-11
EP2301545A1 (en) 2011-03-30
HK1139309A1 (en) 2010-09-17
PT2114406E (pt) 2011-08-25
CN101594869A (zh) 2009-12-02
EP2114406B1 (en) 2011-05-25
CY1111778T1 (el) 2015-10-07
EA016886B1 (ru) 2012-08-30
JP2010514814A (ja) 2010-05-06
CA2673809C (en) 2013-08-13
AU2008203743A1 (en) 2008-07-10
CN101594869B (zh) 2013-08-07

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