PL2120921T3 - Zastosowanie kwasu aminolewulinowego i jego pochodnych - Google Patents

Zastosowanie kwasu aminolewulinowego i jego pochodnych

Info

Publication number: PL2120921T3
Authority: PL; Poland
Prior art keywords: derivatives; aminolevulinic acid; aminolevulinic; acid
Prior art date: 2007-01-11

Application number

PL08701770T

Other languages

English (en)

Inventor

Hans Christian Wulf

Aslak Godal

Jo Klaveness

Per Harald Fuglerud

Original Assignee

Photocure Asa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-01-11

Filing date

2008-01-11

Publication date

2015-12-31

2008-01-11 Application filed by Photocure Asa filed Critical Photocure Asa

2015-12-31 Publication of PL2120921T3 publication Critical patent/PL2120921T3/pl

Links

ZGXJTSGNIOSYLO-UHFFFAOYSA-N 88755TAZ87 Chemical compound NCC(=O)CCC(O)=O ZGXJTSGNIOSYLO-UHFFFAOYSA-N 0.000 title 1
229960002749 aminolevulinic acid Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0061—5-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/0616—Skin treatment other than tanning
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/065—Light sources therefor
- A61N2005/0651—Diodes
- A61N2005/0652—Arrays of diodes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0662—Visible light
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0662—Visible light
- A61N2005/0663—Coloured light

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Bioinformatics & Cheminformatics (AREA)
Radiology & Medical Imaging (AREA)
Biophysics (AREA)
Pathology (AREA)
Virology (AREA)
Dermatology (AREA)
Molecular Biology (AREA)
Emergency Medicine (AREA)
Biochemistry (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Biotechnology (AREA)
Gynecology & Obstetrics (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

PL08701770T 2007-01-11 2008-01-11 Zastosowanie kwasu aminolewulinowego i jego pochodnych PL2120921T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB0700580.4A GB0700580D0 (en)	2007-01-11	2007-01-11	Use
EP08701770.3A EP2120921B1 (en)	2007-01-11	2008-01-11	Use of aminolevulinic acid and derivatives thereof
PCT/GB2008/000086 WO2008084241A2 (en)	2007-01-11	2008-01-11	Use of aminolevulinic acid and derivatives thereof

Publications (1)

Publication Number	Publication Date
PL2120921T3 true PL2120921T3 (pl)	2015-12-31

Family

ID=37809842

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL08701770T PL2120921T3 (pl)	2007-01-11	2008-01-11	Zastosowanie kwasu aminolewulinowego i jego pochodnych

Country Status (13)

Country	Link
US (4)	US8759396B2 (pl)
EP (3)	EP2659888A1 (pl)
JP (2)	JP5814508B2 (pl)
KR (2)	KR20140076641A (pl)
CN (3)	CN104524576A (pl)
CA (2)	CA2675334C (pl)
DK (1)	DK2120921T3 (pl)
ES (2)	ES2546381T3 (pl)
GB (1)	GB0700580D0 (pl)
PL (1)	PL2120921T3 (pl)
PT (1)	PT2120921E (pl)
SI (1)	SI2120921T1 (pl)
WO (1)	WO2008084241A2 (pl)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20110224598A1 (en) *	2010-03-12	2011-09-15	Daniel Barolet	Radiant near infrared light emitting diode exposure as skin preparation
GB0900461D0 (en)	2009-01-12	2009-02-11	Photocure Asa	Photodynamic therapy device
WO2010142457A1 (en) *	2009-06-11	2010-12-16	Photocure Asa	Semi-solid compositions and pharmaceutical products
JP2013521251A (ja) *	2010-03-01	2013-06-10	フォトキュアエイエスエイ	美容組成物
JP6323978B2 (ja)	2010-12-24	2018-05-16	アークレイ株式会社	癌細胞の検出方法
CN102617378B (zh) *	2011-01-26	2016-04-27	上海泺安医药技术有限公司	一种2-(3’-氨基-2’-氧-丙基)丙二酸酯盐及制备
KR101254758B1 (ko) *	2011-02-28	2013-04-15	부산대학교병원	광역동치료의 광증감제로 사용하기 위한 이디티에이를 이용한 아미노레불리닉산 테트라머
KR101254752B1 (ko) *	2011-02-28	2013-04-15	부산대학교 산학협력단	광역동치료의 광증감제로 사용하기 위한 구연산을 이용한 아미노레불리닉산 트라이머
CN102179010B (zh) *	2011-05-27	2013-01-09	吉林大学	脑胶质瘤光动力直接照射治疗装置
BR112014014847B1 (pt)	2011-12-19	2022-08-16	Photocure Asa	Aparelho de aplicação de luz portátil, autônomo, para tratamento fotodinâmico da vulva, e kit
WO2013111719A1 (ja) *	2012-01-26	2013-08-01	Ｓｂｉファーマ株式会社	光線力学的診断剤、及び、フォトブリーチング防止剤
US20140067024A1 (en)	2012-08-30	2014-03-06	Photocure Asa	Dual panel photodynamic therapy lamp
GB201306369D0 (en)	2013-04-09	2013-05-22	Photocure As	Irradiation device
KR20150004092A (ko) *	2013-07-02	2015-01-12	제너럴바이오(주)	칼란코에 추출물이 포함된 항산화 액상 조성물
CN105899201A (zh) *	2013-12-20	2016-08-24	盖尔德马研究及发展公司	光损伤的皮肤的脉冲光动力治疗
PL229756B1 (pl)	2014-11-12	2018-08-31	Tarchominskie Zaklady Farmaceutyczne Polfa Spólka Akcyjna	Krem do stosowania w diagnostyce i terapii z zastosowaniem metody fotodynamicznej
CN109939361B (zh) *	2014-11-19	2021-04-06	夏普株式会社	光动力学治疗装置
WO2017066270A1 (en)	2015-10-15	2017-04-20	Dusa Pharmaceuticals, Inc.	Adjustable illuminator for photodynamic therapy and diagnosis
US10603508B2 (en)	2015-10-15	2020-03-31	Dusa Pharmaceuticals, Inc.	Adjustable illuminators and methods for photodynamic therapy and diagnosis
EP3389716B1 (en)	2015-12-17	2022-03-23	Photocure ASA	Method of photodynamic therapy (pdt) for bladder cancer
US10632324B2 (en)	2017-04-27	2020-04-28	9127-4910 Quebec Inc.	Method for the treatment of skin tissues
US20200261580A1 (en) *	2017-07-17	2020-08-20	Andrea Willey	Photodynamic Therapy Method for Skin Disorders
US10357567B1 (en)	2018-01-12	2019-07-23	Dusa Pharmaceuticals, Inc.	Methods for photodynamic therapy
WO2020038583A1 (en)	2018-08-23	2020-02-27	Biofrontera Bioscience Gmbh	Photodynamic therapy comprising two light exposures at different wavelengths
US20220193124A1 (en)	2019-04-26	2022-06-23	Neopharma Japan Co., Ltd.	Therapeutic Agent for Flavivirus Infection
AU2020303417B2 (en) *	2019-06-25	2025-08-28	Sun Pharmaceutical Industries, Inc.	Methods for reducing pain during photodynamic therapy of actinic keratosis
JPWO2022014654A1 (pl) *	2020-07-15	2022-01-20
CN113620828B (zh) *	2021-08-17	2025-04-01	湖南复瑞生物医药技术有限责任公司	一种5-氨基酮戊酸酯化物、用途和农药组合物
KR102953140B1 (ko) *	2023-08-07	2026-04-16	주식회사 아스트로젠	5-아미노레불린산 유도체 및 이를 포함하는 약학 조성물
WO2026158624A1 (en) *	2025-01-26	2026-07-30	Jiangsu Yahong Meditech Co., Ltd.	Semi-solid pharmaceutical compositions containing stearic acid and palmitic acid

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5955490A (en)	1989-07-28	1999-09-21	Queen's University At Kingston	Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins
US5422093A (en) *	1989-07-28	1995-06-06	Queen's University	Photochemotherapeutic method using 5-aminolevulinic acid and precursors thereof
US5234940A (en) *	1989-07-28	1993-08-10	Queen's University	Photochemotherapeutic method using 5-aminolevulinic acid and precursors thereof
US5079262A (en) *	1989-07-28	1992-01-07	Queen's University At Kingston	Method of detection and treatment of malignant and non-malignant lesions utilizing 5-aminolevulinic acid
US7530461B2 (en) *	1995-03-10	2009-05-12	Photocure Asa	Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
DE122006000051I1 (de) *	1995-03-10	2007-01-04	Photocure Asa	Ester der 5-Aminolevulins{ure als Mittel zur Photosensibillisierung in der Chemotherapie
GB9700396D0 (en) *	1997-01-10	1997-02-26	Photocure As	Photochemotherapeutic compositions
AUPQ044499A0 (en)	1999-05-19	1999-06-10	Commonwealth Scientific And Industrial Research Organisation	Control of wool growth
GB0018528D0 (en)	2000-07-27	2000-09-13	Photocure Asa	Compounds
GB0018527D0 (en) *	2000-07-27	2000-09-13	Photocure Asa	Composition
CA2422865C (en)	2000-08-16	2012-10-16	The General Hospital Corporation D/B/A Massachusetts General Hospital	Aminolevulinic acid photodynamic therapy for treating sebaceous gland disorders
US6723750B2 (en) *	2002-03-15	2004-04-20	Allergan, Inc.	Photodynamic therapy for pre-melanomas
WO2003086460A2 (en)	2002-04-05	2003-10-23	Candela Corporation	High fluence rate activation of photosensitizers for dermatological applications
US20040048842A1 (en) *	2002-09-10	2004-03-11	Mcmillan Kathleen	Method of treating skin disorders
WO2004034889A2 (en) *	2002-10-18	2004-04-29	The Regents Of The University Of California	Photodynamic therapy for ocular neovascularization
US20050209331A1 (en)	2004-03-22	2005-09-22	Syneron Medical Ltd.	Method of treatment of skin
US20050209330A1 (en) *	2004-03-22	2005-09-22	Syneron Medical Ltd.	Method of treatment of skin
GB0406917D0 (en)	2004-03-26	2004-04-28	Photocure Asa	Compounds
GB0424833D0 (en) *	2004-11-10	2004-12-15	Photocure Asa	Method
GB0609809D0 (en) *	2006-05-17	2006-06-28	Photocure Asa	Product

2007
- 2007-01-11 GB GBGB0700580.4A patent/GB0700580D0/en not_active Ceased
2008
- 2008-01-11 KR KR1020147014684A patent/KR20140076641A/ko not_active Ceased
- 2008-01-11 CN CN201410834714.2A patent/CN104524576A/zh active Pending
- 2008-01-11 WO PCT/GB2008/000086 patent/WO2008084241A2/en not_active Ceased
- 2008-01-11 SI SI200831500T patent/SI2120921T1/sl unknown
- 2008-01-11 DK DK08701770.3T patent/DK2120921T3/en active
- 2008-01-11 CA CA2675334A patent/CA2675334C/en active Active
- 2008-01-11 EP EP13173602.7A patent/EP2659888A1/en not_active Withdrawn
- 2008-01-11 ES ES08701770.3T patent/ES2546381T3/es active Active
- 2008-01-11 PL PL08701770T patent/PL2120921T3/pl unknown
- 2008-01-11 EP EP14163782.7A patent/EP2754439B1/en active Active
- 2008-01-11 US US12/523,048 patent/US8759396B2/en active Active
- 2008-01-11 KR KR1020097016703A patent/KR20090118925A/ko not_active Ceased
- 2008-01-11 EP EP08701770.3A patent/EP2120921B1/en not_active Not-in-force
- 2008-01-11 ES ES14163782T patent/ES2900528T3/es active Active
- 2008-01-11 CA CA2784250A patent/CA2784250C/en not_active Expired - Fee Related
- 2008-01-11 CN CN200880002124A patent/CN101631541A/zh active Pending
- 2008-01-11 CN CN201410331370.3A patent/CN104069493A/zh active Pending
- 2008-01-11 JP JP2009545231A patent/JP5814508B2/ja not_active Expired - Fee Related
- 2008-01-11 PT PT87017703T patent/PT2120921E/pt unknown
2012
- 2012-10-10 US US13/648,946 patent/US20130090592A1/en not_active Abandoned
2014
- 2014-01-22 JP JP2014009382A patent/JP5827702B2/ja active Active
2015
- 2015-02-06 US US14/616,278 patent/US20150150972A1/en not_active Abandoned
- 2015-10-02 US US14/873,566 patent/US10543272B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US8759396B2 (en)	2014-06-24
CA2675334C (en)	2014-02-25
EP2120921A2 (en)	2009-11-25
EP2754439A3 (en)	2014-10-01
CN101631541A (zh)	2010-01-20
GB0700580D0 (en)	2007-02-21
WO2008084241A2 (en)	2008-07-17
CN104069493A (zh)	2014-10-01
KR20090118925A (ko)	2009-11-18
CN104524576A (zh)	2015-04-22
JP2014094963A (ja)	2014-05-22
EP2754439A2 (en)	2014-07-16
PT2120921E (pt)	2015-09-30
JP5814508B2 (ja)	2015-11-17
US10543272B2 (en)	2020-01-28
WO2008084241A3 (en)	2008-09-18
US20100137439A1 (en)	2010-06-03
US20150150972A1 (en)	2015-06-04
US20130090592A1 (en)	2013-04-11
JP2010515714A (ja)	2010-05-13
ES2546381T3 (es)	2015-09-23
ES2900528T3 (es)	2022-03-17
JP5827702B2 (ja)	2015-12-02
CA2675334A1 (en)	2008-07-17
EP2120921B1 (en)	2015-06-17
DK2120921T3 (en)	2015-08-24
CA2784250C (en)	2016-03-15
SI2120921T1 (sl)	2015-10-30
CA2784250A1 (en)	2008-07-17
US20160030565A1 (en)	2016-02-04
EP2754439B1 (en)	2021-10-13
EP2659888A1 (en)	2013-11-06
KR20140076641A (ko)	2014-06-20

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