PL2123276T3 - Kompozycja farmaceutyczna zawierająca pochodną pirazyny oraz sposób stosowania pochodnej pirazyny w kombinacji - Google Patents

Kompozycja farmaceutyczna zawierająca pochodną pirazyny oraz sposób stosowania pochodnej pirazyny w kombinacji

Info

Publication number
PL2123276T3
PL2123276T3 PL08711267T PL08711267T PL2123276T3 PL 2123276 T3 PL2123276 T3 PL 2123276T3 PL 08711267 T PL08711267 T PL 08711267T PL 08711267 T PL08711267 T PL 08711267T PL 2123276 T3 PL2123276 T3 PL 2123276T3
Authority
PL
Poland
Prior art keywords
pyrazine derivative
combination
pharmaceutical composition
pyrazine
derivative
Prior art date
Application number
PL08711267T
Other languages
English (en)
Inventor
Masako Maekawa
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of PL2123276T3 publication Critical patent/PL2123276T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL08711267T 2007-02-16 2008-02-14 Kompozycja farmaceutyczna zawierająca pochodną pirazyny oraz sposób stosowania pochodnej pirazyny w kombinacji PL2123276T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2007035975 2007-02-16
EP08711267A EP2123276B1 (en) 2007-02-16 2008-02-14 Pharmaceutical composition comprising pyrazine derivative, and method of using pyrazine derivative in combination
PCT/JP2008/052425 WO2008099874A1 (ja) 2007-02-16 2008-02-14 ピラジン誘導体を含有する医薬組成物およびピラジン誘導体を組み合わせて使用する方法

Publications (1)

Publication Number Publication Date
PL2123276T3 true PL2123276T3 (pl) 2013-04-30

Family

ID=39690101

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08711267T PL2123276T3 (pl) 2007-02-16 2008-02-14 Kompozycja farmaceutyczna zawierająca pochodną pirazyny oraz sposób stosowania pochodnej pirazyny w kombinacji

Country Status (21)

Country Link
US (1) US8759354B2 (pl)
EP (1) EP2123276B1 (pl)
JP (1) JP5255456B2 (pl)
KR (1) KR101479083B1 (pl)
CN (1) CN101610772B (pl)
AU (1) AU2008215397B2 (pl)
BR (1) BRPI0807597B8 (pl)
CA (1) CA2677905C (pl)
CY (1) CY1113435T1 (pl)
DK (1) DK2123276T3 (pl)
ES (1) ES2396595T3 (pl)
HR (1) HRP20130111T1 (pl)
IL (1) IL200285A (pl)
MX (1) MX2009008779A (pl)
NZ (1) NZ578989A (pl)
PL (1) PL2123276T3 (pl)
PT (1) PT2123276E (pl)
RU (1) RU2463051C2 (pl)
SI (1) SI2123276T1 (pl)
WO (1) WO2008099874A1 (pl)
ZA (1) ZA200905536B (pl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010117114A1 (en) * 2009-04-09 2010-10-14 Lg Electronics Inc. Display apparatus
CN103068378B (zh) * 2010-05-10 2016-07-06 中央研究院 具有抗流感活性的扎那米韦膦酸酯同类物及其制备方法
MY161757A (en) 2010-09-30 2017-05-15 Toyama Chemical Co Ltd Meglumine salt of 6-fluoro-3-hydroxy-2-pyrazine carboxamide
SG189161A1 (en) * 2010-09-30 2013-05-31 Toyama Chemical Co Ltd Sodium salt of 6-fluoro-3-hydroxy-2-pyrazine carboxamide
AT510585B1 (de) * 2010-11-18 2012-05-15 Apeptico Forschung & Entwicklung Gmbh Zusammensetzung umfassend ein peptid und ein hemmstoff der viralen neuraminidase
AU2014265483B2 (en) * 2013-05-14 2018-08-02 Biocryst Pharmaceuticals, Inc. Anti-influenza compositions and methods
CN104447583B (zh) * 2014-11-20 2016-08-24 广东东阳光药业有限公司 含有环丁烷取代基的吡嗪类化合物及其组合物及用途
CN104447584B (zh) * 2014-11-20 2016-08-24 广东东阳光药业有限公司 含有环丁烷取代基的吡嗪类化合物及其组合物及用途
CN104447585B (zh) * 2014-11-20 2016-08-24 广东东阳光药业有限公司 吡嗪类化合物及其组合物及用途
CN104402833B (zh) * 2014-11-20 2016-08-24 广东东阳光药业有限公司 含有环丁烷取代基的吡嗪类化合物及其组合物及用途
CN104496918B (zh) * 2014-12-10 2016-08-24 广东东阳光药业有限公司 吡嗪衍生物及其用途
CN104817511B (zh) * 2015-04-27 2017-04-19 济南大学 一种丁烯二酸酐制备法匹拉韦关键中间体的方法
SG10201911957QA (en) * 2015-12-15 2020-02-27 Shionogi & Co Medicine for treating influenza characterized by comprising combination of cap-dependent endonuclease inhibitor with anti-influenza drug
JP7369143B2 (ja) 2018-12-25 2023-10-25 富士フイルム富山化学株式会社 ピラジン誘導体と細胞内におけるピラジン誘導体リボース三リン酸体の量を増加させる化合物とを組み合わせてなるrnaウイルス感染症治療剤
US20230210848A1 (en) * 2020-04-30 2023-07-06 Fujifilm Toyama Chemical Co., Ltd. Coronavirus infection therapeutic agent formed through combination of pyrazine derivative and another coronavirus infection therapeutic drug
EP4159215A4 (en) 2020-05-27 2023-11-22 FUJIFILM Toyama Chemical Co., Ltd. THERAPEUTIC AGENT FOR RNA VIRAL INFECTION OBTAINED BY COMBINATION OF A PYRAZINE DERIVATIVE AND A THIOPURINE DERIVATIVE

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01197437A (ja) * 1988-01-29 1989-08-09 Dso Pharmachim 抗ウイルス薬
TR200100574T2 (tr) * 1998-08-20 2001-07-23 Toyama Chemical Co., Ltd. Nitrojenöz heteroksiklik karboksamid türevlerini içeren antiviral ajanlar
KR100894167B1 (ko) 2001-08-14 2009-04-22 토야마 케미칼 컴퍼니 리미티드 신규의 바이러스 증식저해 ·살바이러스방법 및 신규의피라진뉴클레오티드 ·피라진뉴클레오시드 유사체
JP2005354833A (ja) * 2004-06-11 2005-12-22 Fujinon Corp アクチュエータ
JP4689989B2 (ja) * 2004-08-27 2011-06-01 オリンパス株式会社 振動波リニアモータ及びそれを用いたレンズ装置
DE102008031715A1 (de) 2008-07-04 2010-01-07 Henkel Ag & Co. Kgaa Haarkonditionierende Mittel mit Imidazolinen

Also Published As

Publication number Publication date
JP5255456B2 (ja) 2013-08-07
EP2123276B1 (en) 2012-11-28
RU2009134516A (ru) 2011-03-27
ES2396595T3 (es) 2013-02-22
RU2463051C2 (ru) 2012-10-10
AU2008215397A1 (en) 2008-08-21
BRPI0807597A2 (pt) 2014-05-06
DK2123276T3 (da) 2013-01-02
HRP20130111T1 (hr) 2013-02-28
BRPI0807597B8 (pt) 2021-05-25
CA2677905C (en) 2015-03-24
KR20090121289A (ko) 2009-11-25
AU2008215397B2 (en) 2012-09-06
US8759354B2 (en) 2014-06-24
BRPI0807597B1 (pt) 2021-03-02
CN101610772A (zh) 2009-12-23
PT2123276E (pt) 2013-01-16
WO2008099874A1 (ja) 2008-08-21
CA2677905A1 (en) 2008-08-21
JPWO2008099874A1 (ja) 2010-05-27
CY1113435T1 (el) 2016-06-22
ZA200905536B (en) 2010-10-27
US20100087447A1 (en) 2010-04-08
IL200285A (en) 2014-06-30
SI2123276T1 (sl) 2013-03-29
MX2009008779A (es) 2009-11-05
NZ578989A (en) 2011-07-29
KR101479083B1 (ko) 2015-01-07
CN101610772B (zh) 2013-01-16
IL200285A0 (en) 2010-04-29
EP2123276A4 (en) 2011-05-18
EP2123276A1 (en) 2009-11-25

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