PL2170403T3 - Kompozycje i sposoby hamowania ekspresji genów proapoptotycznych - Google Patents

Kompozycje i sposoby hamowania ekspresji genów proapoptotycznych

Info

Publication number
PL2170403T3
PL2170403T3 PL08763631T PL08763631T PL2170403T3 PL 2170403 T3 PL2170403 T3 PL 2170403T3 PL 08763631 T PL08763631 T PL 08763631T PL 08763631 T PL08763631 T PL 08763631T PL 2170403 T3 PL2170403 T3 PL 2170403T3
Authority
PL
Poland
Prior art keywords
pro
compositions
methods
inhibiting expression
apoptotic genes
Prior art date
Application number
PL08763631T
Other languages
English (en)
Inventor
Hagar Kalinski
Igor Mett
Elena Feinstein
Shai Dr Erlich
Original Assignee
Quark Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quark Pharmaceuticals Inc filed Critical Quark Pharmaceuticals Inc
Publication of PL2170403T3 publication Critical patent/PL2170403T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00—Applications; Uses
    • C12N2320/10—Applications; Uses in screening processes
    • C12N2320/11—Applications; Uses in screening processes for the determination of target sites, i.e. of active nucleic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL08763631T 2007-06-27 2008-06-26 Kompozycje i sposoby hamowania ekspresji genów proapoptotycznych PL2170403T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US93731807P 2007-06-27 2007-06-27
US96432507P 2007-08-10 2007-08-10
PCT/IL2008/000874 WO2009001359A2 (en) 2007-06-27 2008-06-26 Compositions and methods for inhibiting expression of pro-apoptotic genes
EP08763631.2A EP2170403B1 (en) 2007-06-27 2008-06-26 Compositions and methods for inhibiting expression of pro-apoptotic genes

Publications (1)

Publication Number Publication Date
PL2170403T3 true PL2170403T3 (pl) 2014-09-30

Family

ID=40186122

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08763631T PL2170403T3 (pl) 2007-06-27 2008-06-26 Kompozycje i sposoby hamowania ekspresji genów proapoptotycznych

Country Status (9)

Country Link
US (1) US8785408B2 (pl)
EP (1) EP2170403B1 (pl)
DK (1) DK2170403T3 (pl)
ES (1) ES2474176T3 (pl)
HR (1) HRP20140522T1 (pl)
PL (1) PL2170403T3 (pl)
PT (1) PT2170403E (pl)
SI (1) SI2170403T1 (pl)
WO (1) WO2009001359A2 (pl)

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US9771586B2 (en) 2002-11-14 2017-09-26 Thermo Fisher Scientific Inc. RNAi targeting ZNF205
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US20110288155A1 (en) 2008-12-18 2011-11-24 Elena Feinstein Sirna compounds and methods of use thereof
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CN121081472A (zh) 2018-12-13 2025-12-09 拓臻股份有限公司 一种THRβ受体激动剂化合物及其制备方法和用途
US11859213B2 (en) 2019-05-16 2024-01-02 Regents Of The University Of Minnesota Development of superior chimerism by hiPSC engineering and embryo aggregation
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Also Published As

Publication number Publication date
DK2170403T3 (da) 2014-06-16
SI2170403T1 (sl) 2014-07-31
ES2474176T3 (es) 2014-07-08
US20100222409A1 (en) 2010-09-02
HRP20140522T1 (hr) 2014-08-15
EP2170403A4 (en) 2011-06-15
EP2170403A2 (en) 2010-04-07
PT2170403E (pt) 2014-07-17
US8785408B2 (en) 2014-07-22
EP2170403B1 (en) 2014-04-16
WO2009001359A2 (en) 2008-12-31
WO2009001359A3 (en) 2010-03-04

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