PL2175838T5 - Wziewny lek zawierający bezpostaciowy bromek tiotropium - Google Patents

Wziewny lek zawierający bezpostaciowy bromek tiotropium

Info

Publication number: PL2175838T5
Authority: PL; Poland
Prior art keywords: containinig; tiotropium bromide; inhalable medicament; amorphous tiotropium; amorphous
Prior art date: 2007-07-09

Application number

PL08775842T

Other languages

English (en)

Other versions

PL2175838T3 (pl

Inventor

Xian-Ming Zeng

Original Assignee

Norton Healthcare Limited

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-07-09

Filing date

2008-07-03

Publication date

2018-03-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38566522&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2175838(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2008-07-03 Application filed by Norton Healthcare Limited filed Critical Norton Healthcare Limited

2015-05-29 Publication of PL2175838T3 publication Critical patent/PL2175838T3/pl

2018-03-30 Publication of PL2175838T5 publication Critical patent/PL2175838T5/pl

Links

LERNTVKEWCAPOY-VOGVJGKGSA-N C[N+]1(C)[C@H]2C[C@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)C(O)(c1cccs1)c1cccs1 Chemical compound C[N+]1(C)[C@H]2C[C@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)C(O)(c1cccs1)c1cccs1 LERNTVKEWCAPOY-VOGVJGKGSA-N 0.000 title 1
239000003814 drug Substances 0.000 title 1
229960000257 tiotropium bromide Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Epidemiology (AREA)
Pulmonology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Otolaryngology (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

PL08775842T 2007-07-09 2008-07-03 Wziewny lek zawierający bezpostaciowy bromek tiotropium PL2175838T5 (pl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US95882307P	2007-07-09	2007-07-09
GBGB0716026.0A GB0716026D0 (en)	2007-08-16	2007-08-16	An inhalable medicament
PCT/GB2008/002294 WO2009007687A2 (en)	2007-07-09	2008-07-03	An inhalable medicament
EP08775842.1A EP2175838B2 (en)	2007-07-09	2008-07-03	An inhalable medicament containinig amorphous tiotropium bromide

Publications (2)

Publication Number	Publication Date
PL2175838T3 PL2175838T3 (pl)	2015-05-29
PL2175838T5 true PL2175838T5 (pl)	2018-03-30

Family

ID=38566522

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL08775842T PL2175838T5 (pl)	2007-07-09	2008-07-03	Wziewny lek zawierający bezpostaciowy bromek tiotropium

Country Status (20)

Country	Link
US (3)	US8759369B2 (pl)
EP (1)	EP2175838B2 (pl)
JP (1)	JP5552049B2 (pl)
KR (1)	KR101542632B1 (pl)
CN (1)	CN101754749B (pl)
BR (1)	BRPI0813564A2 (pl)
CA (1)	CA2692606C (pl)
CY (1)	CY1115937T1 (pl)
DK (1)	DK2175838T4 (pl)
EA (2)	EA030829B1 (pl)
ES (1)	ES2526647T5 (pl)
GB (1)	GB0716026D0 (pl)
HR (1)	HRP20141175T4 (pl)
IL (2)	IL203180A (pl)
MX (1)	MX2010000315A (pl)
PL (1)	PL2175838T5 (pl)
PT (1)	PT2175838E (pl)
RS (1)	RS53784B2 (pl)
SI (1)	SI2175838T2 (pl)
WO (1)	WO2009007687A2 (pl)

Families Citing this family (15)

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EP1697035B1 (en) *	2003-12-22	2017-11-15	Warren H. Finlay	Powder formation by atmospheric spray-freeze drying
EP1925295A1 (de) *	2006-11-22	2008-05-28	Boehringer Ingelheim Pharma GmbH & Co. KG	Stabile Pulverformulierung enthaltend ein Anticholinergikum
EP2534957B1 (en)	2007-12-14	2015-05-27	AeroDesigns, Inc	Delivering aerosolizable products
GB0801876D0 (en) *	2008-02-01	2008-03-12	Vectura Group Plc	Suspension formulations
EP2172190A1 (en) *	2008-10-02	2010-04-07	Laboratorios Liconsa, S.A.	Inhalable particles comprising tiotropium
US8834931B2 (en)	2009-12-25	2014-09-16	Mahmut Bilgic	Dry powder formulation containing tiotropium for inhalation
GB201200525D0 (en)	2011-12-19	2012-02-29	Teva Branded Pharmaceutical Prod R & D Inc	An inhalable medicament
EP2705838A1 (en) *	2012-09-06	2014-03-12	Xspray Microparticles Ab	Tiotropium preparations
CN103110584A (zh) *	2013-01-29	2013-05-22	青岛大学	一种噻托溴铵粉雾剂及其制备方法
AU2014248455B2 (en)	2013-04-01	2018-12-06	Pulmatrix Operating Company, Inc.	Tiotropium dry powders
EP2913332A1 (en) *	2014-02-27	2015-09-02	Euticals S.P.A.	Crystalline form of tiotropium bromide with lactose
GB201409603D0 (en) *	2014-05-30	2014-07-16	Teva Pharmaceuticals Europ B V	An inhalable medicament
US10034866B2 (en)	2014-06-19	2018-07-31	Teva Branded Pharmaceutical Products R&D, Inc.	Inhalable medicament comprising tiotropium
KR101728116B1 (ko) *	2015-11-03	2017-04-18	한미약품 주식회사	티오트로피움 또는 이의 약학적으로 허용가능한 염을 함유하는 흡입용 건조분말 조성물
US20240058538A1 (en) *	2022-08-16	2024-02-22	Kaleo, Inc.	Devices and methods for delivering reconstituted medicaments

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US5610163A (en)	1989-09-16	1997-03-11	Boehringer Ingelheim Gmbh	Esters of thienyl carboxylic acids and amino alcohols and their quaternization products
DE3931041C2 (de)	1989-09-16	2000-04-06	Boehringer Ingelheim Kg	Ester von Thienylcarbonsäuren mit Aminoalkoholen, ihre Quaternierungsprodukte, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
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WO2002030928A1 (de)	2000-10-12	2002-04-18	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Kristallines monohydrat, verfahren zu dessen herstellung und dessen verwendung zur herstellung eines arzneimittels
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DE10212264A1 (de)	2002-03-20	2003-10-02	Boehringer Ingelheim Pharma	Kristallines Mikronisat, Verfahren zu dessen Herstellung und dessen Verwendung zur Herstellung eines Arzneimittels
GB0219511D0 (en)	2002-08-21	2002-10-02	Norton Healthcare Ltd	Method of preparing dry powder inhalation compositions
DE10339197A1 (de) *	2003-08-22	2005-03-24	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Sprühgetrocknete amorphe Pulver mit geringer Restfeuchte und guter Lagerstabilität
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US7968717B2 (en)	2003-11-03	2011-06-28	Boehringer Ingelhein International Gmbh	Crystalline anhydrate with anticholinergic efficacy
ME00349B (me)	2003-11-03	2011-05-10	Boehringer Ingelheim Int	Novi kristalni anhidrat sa antiholinergij skim dejstvom
SE0303570L (sv)	2003-12-03	2005-06-04	Microdrug Ag	Fukt-känslig medicinsk produkt
CN1270709C (zh) *	2004-01-19	2006-08-23	复旦大学	一种噻托溴铵吸入粉雾剂及其制备方法
EP1737499A4 (en) *	2004-03-09	2009-07-22	Arriva Pharmaceuticals Inc	TREATMENT OF CHRONIC OBSTRUCTIVE LUNG DISEASE BY INHALATION OF LOW DOSES OF A PROTEASE HEMMER
CN1593414A (zh) *	2004-07-02	2005-03-16	上海华拓医药科技发展有限公司	一种噻托溴铵胶囊型吸入粉雾剂及其制备方法
WO2006117299A2 (en)	2005-05-02	2006-11-09	Boehringer Ingelheim International Gmbh	Novel crystalline forms of tiotropium bromide
JP2008540367A (ja)	2005-05-02	2008-11-20	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	新規結晶性臭化チオトロピウム
NZ564697A (en)	2005-06-15	2010-04-30	Boehringer Ingelheim Int	Process for preparing tiotropium salts, tiotropium salts as such and pharmaceutical compositions thereof
US8163913B2 (en)	2005-12-19	2012-04-24	Sicor Inc.	Forms of tiotropium bromide and processes for preparation thereof
EP1923393A1 (en)	2006-11-17	2008-05-21	Boehringer Ingelheim Pharma GmbH & Co. KG	Crystalline form of tiotropium bromide and urea

2007
- 2007-08-16 GB GBGB0716026.0A patent/GB0716026D0/en not_active Ceased
2008
- 2008-07-03 EA EA201500111A patent/EA030829B1/ru not_active IP Right Cessation
- 2008-07-03 DK DK08775842.1T patent/DK2175838T4/en active
- 2008-07-03 KR KR1020107002911A patent/KR101542632B1/ko active Active
- 2008-07-03 RS RS20140699A patent/RS53784B2/sr unknown
- 2008-07-03 BR BRPI0813564-9A patent/BRPI0813564A2/pt not_active Application Discontinuation
- 2008-07-03 SI SI200831348T patent/SI2175838T2/sl unknown
- 2008-07-03 US US12/668,546 patent/US8759369B2/en active Active
- 2008-07-03 JP JP2010515588A patent/JP5552049B2/ja active Active
- 2008-07-03 PL PL08775842T patent/PL2175838T5/pl unknown
- 2008-07-03 CN CN200880023636.0A patent/CN101754749B/zh active Active
- 2008-07-03 EA EA201070115A patent/EA020968B1/ru not_active IP Right Cessation
- 2008-07-03 HR HRP20141175TT patent/HRP20141175T4/hr unknown
- 2008-07-03 MX MX2010000315A patent/MX2010000315A/es active IP Right Grant
- 2008-07-03 EP EP08775842.1A patent/EP2175838B2/en active Active
- 2008-07-03 PT PT87758421T patent/PT2175838E/pt unknown
- 2008-07-03 WO PCT/GB2008/002294 patent/WO2009007687A2/en not_active Ceased
- 2008-07-03 ES ES08775842.1T patent/ES2526647T5/es active Active
- 2008-07-03 CA CA2692606A patent/CA2692606C/en active Active
2010
- 2010-01-06 IL IL203180A patent/IL203180A/en active IP Right Grant
2014
- 2014-01-09 US US14/151,172 patent/US20140127304A1/en not_active Abandoned
- 2014-12-12 CY CY20141101038T patent/CY1115937T1/el unknown
- 2014-12-18 IL IL236360A patent/IL236360A0/en active IP Right Grant
2015
- 2015-02-12 US US14/620,929 patent/US20150150808A1/en not_active Abandoned

Also Published As

Publication number	Publication date
DK2175838T4 (en)	2017-08-28
US20100326437A1 (en)	2010-12-30
GB0716026D0 (en)	2007-09-26
CN101754749B (zh)	2016-04-13
EP2175838B1 (en)	2014-10-08
HRP20141175T4 (hr)	2017-09-22
ES2526647T5 (es)	2017-10-10
HRP20141175T1 (hr)	2015-03-13
KR101542632B1 (ko)	2015-08-06
JP5552049B2 (ja)	2014-07-16
US20140127304A1 (en)	2014-05-08
US8759369B2 (en)	2014-06-24
ES2526647T3 (es)	2015-01-14
CA2692606A1 (en)	2009-01-15
JP2010533156A (ja)	2010-10-21
IL236360A0 (en)	2015-09-24
US20150150808A1 (en)	2015-06-04
SI2175838T2 (sl)	2017-09-29
EA201070115A1 (ru)	2010-06-30
BRPI0813564A2 (pt)	2015-08-25
EP2175838B2 (en)	2017-06-07
MX2010000315A (es)	2010-03-17
DK2175838T3 (en)	2015-01-05
PL2175838T3 (pl)	2015-05-29
KR20100045999A (ko)	2010-05-04
SI2175838T1 (sl)	2015-03-31
IL203180A (en)	2015-01-29
CA2692606C (en)	2014-04-01
PT2175838E (pt)	2015-01-14
CN101754749A (zh)	2010-06-23
WO2009007687A3 (en)	2009-06-04
EA030829B1 (ru)	2018-10-31
EA201500111A1 (ru)	2015-10-30
EA020968B1 (ru)	2015-03-31
RS53784B1 (sr)	2015-06-30
EP2175838A2 (en)	2010-04-21
RS53784B2 (sr)	2018-07-31
WO2009007687A2 (en)	2009-01-15
CY1115937T1 (el)	2017-01-25

Publication	Publication Date	Title
PL2175838T3 (pl)	2015-05-29	Wziewny lek zawierający bezpostaciowy bromek tiotropium
IL242205A (en)	2017-07-31	Inhalation-powered inhaler
ZA201104184B (en)	2012-08-29	Inhaler device
EP2512564A4 (en)	2017-11-01	Medicament delivery device
EP2588163A4 (en)	2017-12-20	Medicament delivery device
IL246189B (en)	2019-08-29	Medicine in dry powder form
EP2493529A4 (en)	2014-12-17	APPARATUS FOR MEDICAMENT ADMINISTRATION
EP2482874A4 (en)	2014-11-26	APPARATUS FOR MEDICAMENT ADMINISTRATION
ZA201101735B (en)	2012-05-30	Inhalable particles comprising tiotropium
PL2203205T3 (pl)	2015-10-30	Inhalator
IL213502A (en)	2017-02-28	Use of agonist d1 / d2 compounds for drug preparation
ZA201501986B (en)	2016-10-26	An inhalable medicament comprising tiotropium
GB0803054D0 (en)	2008-03-26	Medicament
EP2310022A4 (en)	2011-08-24	TOPIC MEDICINE
GB0915319D0 (en)	2009-10-07	Combination medicament
PL2298415T3 (pl)	2013-11-29	Mikronizat bromku tiotropiowego
GB0901487D0 (en)	2009-03-11	Asthma Therapy
GB0820625D0 (en)	2008-12-17	A medicament
TH0901004442B (th)	2016-02-05	อนุพันธ์สูดดมได้ที่ประกอบรวมด้วยทิโอโทรเพียม
HU0800362D0 (en)	2008-08-28	Inhaler device
TWM373745U (en)	2010-02-11	Bi-directionally operable medicine inhalation device
PH32007000031S1 (en)	2007-09-10	Inhaler device
GB0803395D0 (en)	2008-04-02	Medicament
AU2010903564A0 (en)	2010-08-26	Therapeutic pillow
AU2008900693A0 (en)	2008-02-28	A Therapeutic Device