PL2187880T3 - Kompozycje i sposoby do leczenia zwyrodnienia plamki żółtej - Google Patents
Kompozycje i sposoby do leczenia zwyrodnienia plamki żółtejInfo
- Publication number
- PL2187880T3 PL2187880T3 PL08830106T PL08830106T PL2187880T3 PL 2187880 T3 PL2187880 T3 PL 2187880T3 PL 08830106 T PL08830106 T PL 08830106T PL 08830106 T PL08830106 T PL 08830106T PL 2187880 T3 PL2187880 T3 PL 2187880T3
- Authority
- PL
- Poland
- Prior art keywords
- compositions
- methods
- macular degeneration
- treating macular
- treating
- Prior art date
Links
- 208000002780 macular degeneration Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99337907P | 2007-09-12 | 2007-09-12 | |
| PCT/US2008/010676 WO2009035673A1 (en) | 2007-09-12 | 2008-09-12 | Compositions and methods for treating macular degeneration |
| EP08830106.4A EP2187880B1 (en) | 2007-09-12 | 2008-09-12 | Compositions and methods for treating macular degeneration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2187880T3 true PL2187880T3 (pl) | 2014-05-30 |
Family
ID=40452355
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL08830106T PL2187880T3 (pl) | 2007-09-12 | 2008-09-12 | Kompozycje i sposoby do leczenia zwyrodnienia plamki żółtej |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | USRE47045E1 (pl) |
| EP (2) | EP2187880B1 (pl) |
| JP (2) | JP5149388B2 (pl) |
| DK (1) | DK2187880T3 (pl) |
| ES (1) | ES2449150T3 (pl) |
| PL (1) | PL2187880T3 (pl) |
| PT (1) | PT2187880E (pl) |
| WO (1) | WO2009035673A1 (pl) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3326623A1 (en) | 2003-03-14 | 2018-05-30 | University of Washington | Retinoid replacements and opsin agonists and methods for the use thereof |
| NZ587006A (en) | 2004-06-18 | 2011-12-22 | Univ Washington | 11-cis-Retinal derivatives and methods for the use thereof for the treatment of visual disorders |
| WO2009035673A1 (en) | 2007-09-12 | 2009-03-19 | Trustees Of Columbia University In The City Of Newyork | Compositions and methods for treating macular degeneration |
| WO2009102418A1 (en) | 2008-02-11 | 2009-08-20 | University Of Washington | Methods for the treatment and prevention of age-related retinal dysfunction |
| US20090312438A1 (en) * | 2008-06-13 | 2009-12-17 | Bernstein Paul S | Compositions and Methods for Attenuating the Formation of A2E in the Retinal Pigment Epithelium |
| CN102612375B (zh) | 2009-09-15 | 2016-01-27 | Qlt股份有限公司 | 含有在脂质媒介物中的9-顺式-视黄酯的药物制剂 |
| CN107308143A (zh) | 2010-04-19 | 2017-11-03 | 诺维利昂治疗股份有限公司 | 用于治疗或改善与内源性类视黄醇缺乏有关的视觉障碍的治疗方案和方法 |
| JP6576636B2 (ja) | 2012-03-01 | 2019-09-18 | ノベリオン セラピューティクス インコーポレイテッド | 内因性レチノイド欠乏に関連する視覚障害における視覚機能を改善するための治療的計画および方法 |
| WO2013185055A1 (en) | 2012-06-07 | 2013-12-12 | Beth Israel Deaconess Medical Center, Inc. | Methods and compositions for the inhibition of pin1 |
| ES3012058T3 (en) * | 2014-02-13 | 2025-04-08 | Katairo Gmbh | Compounds for the treatment of lipofuscin related diseases |
| US20170112792A1 (en) * | 2014-03-21 | 2017-04-27 | Beth Israel Deaconess Medical Center, Inc. | Enhanced atra-related compounds derived from structure-activity relationships and modeling for inhibiting pin1 |
| WO2016011265A2 (en) | 2014-07-17 | 2016-01-21 | Beth Israel Deaconess Medical Center, Inc. | Biomarkers for pin1-associated disorders |
| KR102276424B1 (ko) * | 2014-10-06 | 2021-07-12 | 삼성전자주식회사 | 로-키나제 저해제를 포함하는 세포의 노화를 감소시키기 위한 조성물 및 그의 용도 |
| US9173915B1 (en) | 2014-10-10 | 2015-11-03 | Peter F. Kador | Antioxidant eye drops |
| US10548864B2 (en) | 2015-03-12 | 2020-02-04 | Beth Israel Deaconess Medical Center, Inc. | Enhanced ATRA-related compounds for the treatment of proliferative diseases, autoimmune diseases, and addiction conditions |
| US20200025685A1 (en) * | 2016-12-15 | 2020-01-23 | Codiak Biosciences, Inc. | Methods of measuring exosomes using intrinsic fluorescence |
| CN118121573B (zh) * | 2022-12-01 | 2025-08-05 | 复旦大学 | 一种氘代维生素a及其衍生物的用途 |
| EP4731619A2 (en) * | 2023-06-20 | 2026-04-29 | The Trustees Of Columbia University In The City Of New York | Novel co-drug, co-administration, and sequential administration of bispecific rbp4/ttr ligand and c20-d3-retinol |
| AU2024312789A1 (en) * | 2023-06-20 | 2026-01-29 | Rensselaer Polytechnic Institute | Novel co-drug, co-administration, and sequential administration of selective ttr ligand and c20-d3-retinol |
| WO2025147228A1 (en) | 2024-01-02 | 2025-07-10 | Alkeus Pharmaceuticals, Inc. | Treatment for asymptomatic stargardt disease patients with gildeuretinol acetate |
| WO2025147467A1 (en) | 2024-01-02 | 2025-07-10 | Alkeus Pharmaceuticals, Inc. | 10mg to 35mg of gildeuretinol for use in the treatment of stargardt disease |
| WO2025153898A1 (en) * | 2024-01-19 | 2025-07-24 | Gene Company Pty Ltd | Retinoid compositions and methods of use |
| WO2026050657A1 (en) | 2024-08-30 | 2026-03-05 | Alkeus Pharmaceuticals, Inc. | Gildeuretinol for use for treating geographic atrophy and neovascular age-related macular degeneration |
| CN120441428A (zh) * | 2025-05-15 | 2025-08-08 | 复旦大学 | 一种双异戊二烯衍生物及其用途 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5310764A (en) | 1992-05-08 | 1994-05-10 | Steven Baranowitz | Treatment of age related macular degeneration with beta-carotene |
| US5508456A (en) * | 1993-07-30 | 1996-04-16 | Ligand Pharmaceuticals Incorporated | 9-cis tritium-labeled retinoids and intermediates, methods for their synthesis and methods for their use in discovering retinoid X receptor ligands |
| US5489611A (en) | 1995-02-10 | 1996-02-06 | Warner-Lambert Company | Method for lowering plasma levels of lipoprotein (a) |
| US8198334B2 (en) | 1997-10-27 | 2012-06-12 | Pathologica Llc | Methods for modulating macrophage proliferation in ocular disease using polyamine analogs |
| US6593104B1 (en) | 1999-02-12 | 2003-07-15 | University Of Iowa Research Foundation | Macular degeneration diagnostics and therapeutics |
| US20030149997A1 (en) | 1999-02-19 | 2003-08-07 | Hageman Gregory S. | Diagnostics and therapeutics for arterial wall disruptive disorders |
| CA2385475A1 (en) | 1999-08-16 | 2001-02-22 | Human Genome Sciences, Inc. | 18 human secreted proteins |
| US20040009907A1 (en) | 2001-02-26 | 2004-01-15 | Alsobrook John P. | Proteins and nucleic acids encoding same |
| US20030032078A1 (en) | 2001-01-23 | 2003-02-13 | Board Of Regents, The University Of Texas System | Methods and compositions for the treatment of macular and retinal degenerations |
| NZ516873A (en) | 2001-02-12 | 2003-11-28 | Warner Lambert Co | Compositions containing retinoids and erb inhibitors and their use in inhibiting retinoid skin damage |
| EP1368296A1 (en) | 2001-03-14 | 2003-12-10 | Eli Lilly And Company | Fluorinated trienes and their use as rxr modulators |
| US6660297B2 (en) | 2001-03-23 | 2003-12-09 | Bausch & Lomb Incorporated | Nutritional supplement to treat macular degeneration |
| US20040121407A1 (en) | 2002-09-06 | 2004-06-24 | Elixir Pharmaceuticals, Inc. | Regulation of the growth hormone/IGF-1 axis |
| JP2006516027A (ja) | 2002-12-02 | 2006-06-15 | ジェンベク、インコーポレイティッド | 眼関連障害の治療用材料および治療方法 |
| JP2006526662A (ja) | 2003-06-05 | 2006-11-24 | アシュカル,チャールズ | 過増殖性細胞疾患を治療する方法 |
| US7267830B2 (en) | 2003-12-19 | 2007-09-11 | Alcon, Inc. | Composition and methods for inhibiting the progression macular degeneration and promoting healthy vision |
| FR2864871A1 (fr) | 2004-01-06 | 2005-07-08 | Thomson Licensing Sa | Methode de decouverte d'un reseau domestique et appareil implementant la methode |
| US7309487B2 (en) | 2004-02-09 | 2007-12-18 | George Inana | Methods and compositions for detecting and treating retinal diseases |
| US7566808B2 (en) | 2004-02-17 | 2009-07-28 | President And Fellows Of Harvard College | Management of ophthalmologic disorders, including macular degeneration |
| CA2601278C (en) * | 2004-03-17 | 2014-06-10 | Lars Michael Larsen | Prevention of retinopathy by inhibition of the visual cycle |
| US20060089411A1 (en) * | 2004-08-07 | 2006-04-27 | Gierhart Dennis L | Treatment of Stargardt's disease and other lipofuscin disorders with combined retinaldehyde inhibitor and zeaxanthin |
| AU2005287343A1 (en) * | 2004-08-18 | 2006-03-30 | Sirion Therapeutics, Inc. | Combination compositions comprising 13-cis-retinyl derivatives and uses thereof to treat opthalmic disorders |
| EP1804788A4 (en) | 2004-10-25 | 2008-05-21 | Sirion Therapeutics Inc | DETECTION AND ANALYSIS OF FLUORESCENT MOLECULES RELATING TO OPHTHALMOLOGY |
| JP2008519054A (ja) | 2004-11-04 | 2008-06-05 | シリオン セラピューティクス, インコーポレイテッド | レチノール−レチノール結合タンパク質(rbp)−トランスチレチン(ttr)複合体の形成のモジュレーター |
| CA2584845C (en) | 2004-12-08 | 2009-02-17 | Sirion Therapeutics, Inc. | Methods, assays and compositions for treating retinol-related diseases |
| US20070014833A1 (en) | 2005-03-30 | 2007-01-18 | Sirtris Pharmaceuticals, Inc. | Treatment of eye disorders with sirtuin modulators |
| US20060292099A1 (en) | 2005-05-25 | 2006-12-28 | Michael Milburn | Treatment of eye disorders with sirtuin modulators |
| AU2006249866B2 (en) | 2005-05-26 | 2011-10-13 | Aldeyra Therapeutics, Inc. | Compositions and methods of treating retinal disease |
| UA81382C2 (en) * | 2005-07-11 | 2007-12-25 | Composition for treating retinol-related diseases by modulation of retinol binding | |
| JPWO2007037188A1 (ja) * | 2005-09-27 | 2009-04-09 | 北海道公立大学法人 札幌医科大学 | 血管透過性亢進に起因する眼疾患の予防及び治療のための医薬 |
| WO2009035673A1 (en) | 2007-09-12 | 2009-03-19 | Trustees Of Columbia University In The City Of Newyork | Compositions and methods for treating macular degeneration |
| US8677809B2 (en) | 2008-06-16 | 2014-03-25 | Oxford Instruments Plc | Thermal measurements using multiple frequency atomic force microscopy |
| US8263601B2 (en) | 2009-02-27 | 2012-09-11 | Concert Pharmaceuticals, Inc. | Deuterium substituted xanthine derivatives |
| ES2469849T3 (es) | 2009-06-18 | 2014-06-20 | Concert Pharmaceuticals Inc. | Derivados deuterados de isoindolin-1,3-diona como inhibidores de PDE4 y TNF-alfa |
-
2008
- 2008-09-12 WO PCT/US2008/010676 patent/WO2009035673A1/en not_active Ceased
- 2008-09-12 US US15/343,016 patent/USRE47045E1/en active Active
- 2008-09-12 PL PL08830106T patent/PL2187880T3/pl unknown
- 2008-09-12 EP EP08830106.4A patent/EP2187880B1/en active Active
- 2008-09-12 ES ES08830106.4T patent/ES2449150T3/es active Active
- 2008-09-12 US US12/733,631 patent/US8877809B2/en not_active Ceased
- 2008-09-12 EP EP13186626.1A patent/EP2687208A1/en active Pending
- 2008-09-12 PT PT88301064T patent/PT2187880E/pt unknown
- 2008-09-12 JP JP2010524874A patent/JP5149388B2/ja active Active
- 2008-09-12 DK DK08830106.4T patent/DK2187880T3/da active
-
2012
- 2012-11-29 JP JP2012260971A patent/JP5695017B2/ja active Active
-
2014
- 2014-10-09 US US14/510,975 patent/US9486432B2/en active Active
-
2016
- 2016-11-04 US US15/344,102 patent/US20170128403A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009035673A8 (en) | 2009-07-02 |
| PT2187880E (pt) | 2014-03-25 |
| US20110034554A1 (en) | 2011-02-10 |
| US8877809B2 (en) | 2014-11-04 |
| US20150133549A1 (en) | 2015-05-14 |
| EP2187880A4 (en) | 2010-09-08 |
| US9486432B2 (en) | 2016-11-08 |
| ES2449150T3 (es) | 2014-03-18 |
| USRE47045E1 (en) | 2018-09-18 |
| JP5695017B2 (ja) | 2015-04-01 |
| JP2013049711A (ja) | 2013-03-14 |
| WO2009035673A1 (en) | 2009-03-19 |
| JP2010539168A (ja) | 2010-12-16 |
| EP2187880A1 (en) | 2010-05-26 |
| JP5149388B2 (ja) | 2013-02-20 |
| US20170128403A1 (en) | 2017-05-11 |
| EP2687208A1 (en) | 2014-01-22 |
| DK2187880T3 (da) | 2014-03-10 |
| EP2187880B1 (en) | 2013-12-18 |
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