PL2207773T3 - Związek heterocykliczny i kompozycja farmaceutyczna zawierająca ten związek - Google Patents

Związek heterocykliczny i kompozycja farmaceutyczna zawierająca ten związek

Info

Publication number
PL2207773T3
PL2207773T3 PL08845000T PL08845000T PL2207773T3 PL 2207773 T3 PL2207773 T3 PL 2207773T3 PL 08845000 T PL08845000 T PL 08845000T PL 08845000 T PL08845000 T PL 08845000T PL 2207773 T3 PL2207773 T3 PL 2207773T3
Authority
PL
Poland
Prior art keywords
pharmaceutical composition
heterocyclic compound
heterocyclic
compound
pharmaceutical
Prior art date
Application number
PL08845000T
Other languages
English (en)
Inventor
Takumi Sumida
Fujio Tabusa
Kazuo Sekiguchi
Takeshi Kodama
Koichi Yasumura
Yutaka Kojima
Masaaki Motoyama
Keisuke Miyajima
Kenji Yoshida
Keizo Kan
Makoto Sakamoto
Hideki Takasu
Takashi Nakagawa
Naoto Ohi
Yasuo Harada
Norikazu Hashimoto
Hironori Matsuyama
Masatoshi Iida
Shigekazu Fujita
Tae Fukushima
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of PL2207773T3 publication Critical patent/PL2207773T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL08845000T 2007-10-30 2008-10-29 Związek heterocykliczny i kompozycja farmaceutyczna zawierająca ten związek PL2207773T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2007281601 2007-10-30
JP2007336157 2007-12-27
EP08845000A EP2207773B1 (en) 2007-10-30 2008-10-29 Heterocyclic compound and pharmaceutical composition thereof
PCT/JP2008/070153 WO2009057811A2 (en) 2007-10-30 2008-10-29 Heterocyclic compound and pharmaceutical composition thereof

Publications (1)

Publication Number Publication Date
PL2207773T3 true PL2207773T3 (pl) 2012-11-30

Family

ID=40474791

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08845000T PL2207773T3 (pl) 2007-10-30 2008-10-29 Związek heterocykliczny i kompozycja farmaceutyczna zawierająca ten związek

Country Status (28)

Country Link
US (1) US8551999B2 (pl)
EP (1) EP2207773B1 (pl)
JP (1) JP5236002B2 (pl)
KR (1) KR20100092469A (pl)
CN (2) CN103224488A (pl)
AR (1) AR069065A1 (pl)
AU (1) AU2008319719B2 (pl)
BR (1) BRPI0819232A2 (pl)
CA (1) CA2703240A1 (pl)
CL (1) CL2008003265A1 (pl)
CO (1) CO6210724A2 (pl)
CY (1) CY1113812T1 (pl)
DK (1) DK2207773T3 (pl)
ES (1) ES2390710T3 (pl)
HR (1) HRP20120748T1 (pl)
IL (1) IL204942A0 (pl)
MX (1) MX2010004893A (pl)
MY (1) MY148482A (pl)
NZ (1) NZ584573A (pl)
PE (1) PE20090949A1 (pl)
PL (1) PL2207773T3 (pl)
PT (1) PT2207773E (pl)
RU (1) RU2010121857A (pl)
SI (1) SI2207773T1 (pl)
TW (1) TWI440638B (pl)
UA (1) UA100248C2 (pl)
WO (1) WO2009057811A2 (pl)
ZA (1) ZA201002547B (pl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA200700811B (en) 2004-08-06 2008-10-29 Otsuka Pharma Co Ltd Aromatic compound
CN101321529B (zh) * 2005-12-05 2012-09-05 大塚制药株式会社 作为抗肿瘤剂的二芳基醚衍生物
UA95978C2 (ru) * 2006-10-02 2011-09-26 Оцука Фармас'Ютікел Ко., Лтд. Ингибитор активации stat3/5
JO3265B1 (ar) 2008-12-09 2018-09-16 Novartis Ag مثبطات بيريديلوكسى اندولات vegf-r2 واستخدامها لعلاج المرض
JP5688918B2 (ja) * 2009-04-28 2015-03-25 大塚製薬株式会社 医薬組成物
CN102574843B (zh) 2009-10-22 2015-06-17 法博太科制药有限公司 抗纤维化剂的稠环类似物
HRP20141190T1 (hr) * 2010-01-29 2015-01-30 Otsuka Pharmaceutical Co., Ltd. Disupstituirani derivati piridina kao antikancerogena sredstva
US9040555B2 (en) * 2012-01-26 2015-05-26 Angion Biomedica Corp. Antifibrotic compounds and uses thereof
HUE038700T2 (hu) 2012-03-01 2018-11-28 Allergan Inc Benzofuran-2-szulfonamid származékok, mint kemokinreceptor-modulációk
CN105102448B (zh) 2013-02-28 2018-03-06 百时美施贵宝公司 作为rock1和rock2抑制剂的苯基吡唑衍生物
AR094929A1 (es) 2013-02-28 2015-09-09 Bristol Myers Squibb Co Derivados de fenilpirazol como inhibidores potentes de rock1 y rock2
JP7185631B2 (ja) 2017-02-03 2022-12-07 サータ セラピューティクス プロプライエタリー リミテッド 抗線維化化合物
CN108721621B (zh) * 2017-04-14 2022-03-01 中国科学院上海高等研究院 抑制肝纤维化的小分子化合物及应用
CN108033918B (zh) * 2017-12-28 2020-12-25 西安欧得光电材料有限公司 一种光电材料中间体2-氯-4-苯基苯并[h]喹唑啉的合成方法
CN112300145B (zh) * 2019-07-31 2023-07-21 上海宇耀生物科技有限公司 一类靶向stat3双功能磷酸化位点的三芳香环类化合物及其应用
JP2023175057A (ja) * 2020-10-29 2023-12-12 クミアイ化学工業株式会社 縮合ヘテロ環誘導体及びそれを有効成分として含有する除草剤
CN120981455A (zh) * 2023-03-27 2025-11-18 上海宇耀生物科技有限公司 三芳香环类衍生物的盐、其晶型、制备方法和用途
CN116715657B (zh) * 2023-04-19 2025-07-11 河南省锐达医药科技有限公司 一种二芳基乙炔类化合物、其制备方法及应用
CN116768864B (zh) * 2023-06-25 2025-08-01 河南省锐达医药科技有限公司 一种哌嗪吲哚酰胺类化合物、其制备方法及应用
CN118772123B (zh) * 2024-06-14 2025-09-16 河南省锐达医药科技有限公司 一种哌嗪-1-甲基吲哚-2-甲酰胺衍生物、其制备方法及应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR015733A1 (es) 1998-03-25 2001-05-16 Otsuka Pharma Co Ltd DERIVADO DE PIRIDINA, EL PRODUCTO Y LA COMPOSICIoN FARMACEUTICA QUE CONTIENE DICHO DERIVADO.
JP2001089412A (ja) * 1999-09-22 2001-04-03 Otsuka Pharmaceut Co Ltd ベンゼン誘導体またはその医薬的に許容される塩
JP2001089450A (ja) * 1999-09-22 2001-04-03 Otsuka Pharmaceut Co Ltd ピリジン誘導体含有医薬製剤
AU9598601A (en) * 2000-10-20 2002-04-29 Eisai Co Ltd Nitrogenous aromatic ring compounds

Also Published As

Publication number Publication date
CL2008003265A1 (es) 2010-02-05
TWI440638B (zh) 2014-06-11
MX2010004893A (es) 2010-05-19
DK2207773T3 (da) 2012-09-10
US8551999B2 (en) 2013-10-08
CN101842367A (zh) 2010-09-22
JP2011502115A (ja) 2011-01-20
WO2009057811A3 (en) 2009-07-09
CN103224488A (zh) 2013-07-31
BRPI0819232A2 (pt) 2016-11-01
EP2207773B1 (en) 2012-07-11
CA2703240A1 (en) 2009-05-07
TW200922932A (en) 2009-06-01
ZA201002547B (en) 2011-08-31
IL204942A0 (en) 2010-11-30
PE20090949A1 (es) 2009-07-13
ES2390710T3 (es) 2012-11-15
SI2207773T1 (sl) 2012-09-28
PT2207773E (pt) 2012-10-09
JP5236002B2 (ja) 2013-07-17
MY148482A (en) 2013-04-30
US20100261720A1 (en) 2010-10-14
RU2010121857A (ru) 2011-12-10
HRP20120748T1 (hr) 2012-10-31
AU2008319719A1 (en) 2009-05-07
AR069065A1 (es) 2009-12-23
CO6210724A2 (es) 2010-10-20
CY1113812T1 (el) 2016-07-27
NZ584573A (en) 2012-05-25
WO2009057811A2 (en) 2009-05-07
KR20100092469A (ko) 2010-08-20
UA100248C2 (en) 2012-12-10
EP2207773A2 (en) 2010-07-21
AU2008319719B2 (en) 2013-12-12

Similar Documents

Publication Publication Date Title
IL204942A0 (en) Heterocyclic compound and pharmaceutical composition thereof
HUS1800007I1 (hu) Gyógyászati készítmény
IL194242A0 (en) Heterocyclic compounds and pharmaceutical compositions containing the same
EP2152079A4 (en) HETEROCYCLIC COMPOUNDS AND USES THEREOF
ZA201308294B (en) Heterocyclic compounds and their uses
ZA200808530B (en) Pharmaceutical composition for external use
ZA200808531B (en) Pharmaceutical composition for external use
EP2133095A4 (en) PHARMACEUTICAL COMPOSITION
EP2133094A4 (en) PHARMACEUTICAL COMPOSITION
IL200885A (en) A history of mannich-based compounds and pharmacological preparations including them
IL200125A0 (en) Pharmaceutical composition
IL207276A0 (en) Benzodiazepine compound and pharmaceutical composition
EP2224805A4 (en) PHARMACEUTICAL COMPOSITION
EP2224915A4 (en) PHARMACEUTICAL COMPOSITIONS
IL201894A0 (en) Quinolone compound and pharmaceutical composition
EP2070919A4 (en) SPIROCHINONE COMPOUND AND PHARMACEUTICAL COMPOSITION
EP2224808A4 (en) PHARMACEUTICAL COMPOSITION
EP2114404A4 (en) COMPOUND AND PHARMACEUTICAL COMPOSITION
IL205975A0 (en) Pharmaceutical composition
IL205931A0 (en) Pharmaceutical composition
HK1142819A (en) Heterocyclic compound and pharmaceutical composition thereof
AU2007904647A0 (en) Pharmaceutical Compound and Composition
ZA200906568B (en) Heterocyclic compounds and their uses
GB0717036D0 (en) Pharmaceutical composition
GB0712558D0 (en) Pharmaceutical composition