PL2222839T3 - Sposoby i kompozycje do modulowania i różnicowania pluripotencjalnych komórek - Google Patents

Sposoby i kompozycje do modulowania i różnicowania pluripotencjalnych komórek

Info

Publication number
PL2222839T3
PL2222839T3 PL08856546T PL08856546T PL2222839T3 PL 2222839 T3 PL2222839 T3 PL 2222839T3 PL 08856546 T PL08856546 T PL 08856546T PL 08856546 T PL08856546 T PL 08856546T PL 2222839 T3 PL2222839 T3 PL 2222839T3
Authority
PL
Poland
Prior art keywords
compositions
methods
pluripotential cells
modulating differentiation
differentiation
Prior art date
Application number
PL08856546T
Other languages
English (en)
Inventor
Irina Aizman
Original Assignee
Sanbio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanbio Inc filed Critical Sanbio Inc
Publication of PL2222839T3 publication Critical patent/PL2222839T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
    • C12N2501/42—Notch; Delta; Jagged; Serrate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PL08856546T 2007-12-03 2008-12-03 Sposoby i kompozycje do modulowania i różnicowania pluripotencjalnych komórek PL2222839T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US521107P 2007-12-03 2007-12-03
US12594108P 2008-04-30 2008-04-30
US13157708P 2008-06-10 2008-06-10
EP08856546.0A EP2222839B1 (en) 2007-12-03 2008-12-03 Methods and compositions for modulating differentiation of pluripotential cells
PCT/US2008/013299 WO2009073180A2 (en) 2007-12-03 2008-12-03 Methods and compositions for modulating differentiation of pluripotential cells

Publications (1)

Publication Number Publication Date
PL2222839T3 true PL2222839T3 (pl) 2016-02-29

Family

ID=40718417

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08856546T PL2222839T3 (pl) 2007-12-03 2008-12-03 Sposoby i kompozycje do modulowania i różnicowania pluripotencjalnych komórek

Country Status (7)

Country Link
US (1) US20110306137A1 (pl)
EP (3) EP2222839B1 (pl)
DK (1) DK2222839T3 (pl)
ES (2) ES2551356T3 (pl)
PL (1) PL2222839T3 (pl)
PT (1) PT2222839E (pl)
WO (1) WO2009073180A2 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003207064B2 (en) 2002-02-06 2006-07-13 Sanbio, Inc. Method of differentiating/inducing bone marrow interstitial cells into nerve cells and skeleton muscle cells by transferring Notch gene
US10316288B2 (en) * 2008-04-30 2019-06-11 Sanbio, Inc. Neural regenerating cells with alterations in DNA methylation
EP2806881A1 (en) 2012-01-27 2014-12-03 SanBio, Inc. Methods and compositions for modulating angiogenesis and vasculogenesis
CN104519891B (zh) 2012-05-16 2019-03-22 桑比欧公司 用于治疗创伤性脑损伤和用于调节神经原性细胞迁移的方法和组合物
WO2014058464A1 (en) 2012-10-09 2014-04-17 Sanbio, Inc. Methods and compositions for treatment of retinal degeneration
WO2016210256A1 (en) * 2015-06-25 2016-12-29 The University Of Florida Research Foundation, Inc. Conductive nonwoven mat and method of using the conductive nonwoven mat

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002513545A (ja) 1998-05-07 2002-05-14 ザ ユニヴァーシティー オブ サウス フロリダ 脳および脊髄修復のためのニューロン源としての骨髄細胞
US6534261B1 (en) 1999-01-12 2003-03-18 Sangamo Biosciences, Inc. Regulation of endogenous gene expression in cells using zinc finger proteins
US7015037B1 (en) * 1999-08-05 2006-03-21 Regents Of The University Of Minnesota Multiponent adult stem cells and methods for isolation
EP1749884A1 (en) 2000-02-11 2007-02-07 Philadelphia, Health and Education Corporation Differentiation of bone marrow cells into neuronal cells and uses therefor
US20030003090A1 (en) 2001-05-31 2003-01-02 Prockop Darwin J. Directed in vitro differentiation of marrow stromal cells into neural cell progenitors
JP3886346B2 (ja) 2001-06-22 2007-02-28 サンバイオ，インコーポレイティド 骨髄間質細胞由来Ｓｃｈｗａｎｎ細胞を含む神経再生用医薬組成物
US7129034B2 (en) 2001-10-25 2006-10-31 Cedars-Sinai Medical Center Differentiation of whole bone marrow
AU2003207064B2 (en) * 2002-02-06 2006-07-13 Sanbio, Inc. Method of differentiating/inducing bone marrow interstitial cells into nerve cells and skeleton muscle cells by transferring Notch gene
US20030181380A1 (en) * 2002-03-08 2003-09-25 Pear Warren S. Modulating lymphoid commitment and survival
US20040235165A1 (en) 2003-05-19 2004-11-25 Darwin Prockop In vitro differentiation of adult stem cells
ATE523587T1 (de) * 2004-04-12 2011-09-15 Sanbio Inc Eigenschaften neuronaler vorläuferzellen zeigende zellen

Also Published As

Publication number Publication date
US20110306137A1 (en) 2011-12-15
EP2985341A2 (en) 2016-02-17
ES2787513T3 (es) 2020-10-16
DK2222839T3 (en) 2015-12-21
EP2222839A4 (en) 2012-02-01
EP2222839A2 (en) 2010-09-01
PT2222839E (pt) 2015-11-30
EP3696261A1 (en) 2020-08-19
EP2222839B1 (en) 2015-09-16
EP2985341A3 (en) 2016-06-01
ES2551356T3 (es) 2015-11-18
EP2985341B1 (en) 2020-04-01
WO2009073180A2 (en) 2009-06-11
WO2009073180A3 (en) 2009-10-15

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