PL2240490T3 - Związki organiczne - Google Patents

Związki organiczne

Info

Publication number: PL2240490T3
Authority: PL; Poland
Prior art keywords: organic compounds; compounds; organic
Prior art date: 2007-12-06

Application number

PL08860360T

Other languages

English (en)

Inventor

Peng Li

Original Assignee

Takeda Pharmaceuticals Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-12-06

Filing date

2008-12-06

Publication date

2014-02-28

2008-12-06 Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co

2014-02-28 Publication of PL2240490T3 publication Critical patent/PL2240490T3/pl

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Endocrinology (AREA)
Immunology (AREA)
Reproductive Health (AREA)
Pulmonology (AREA)
Psychiatry (AREA)
Epidemiology (AREA)
Gynecology & Obstetrics (AREA)
Urology & Nephrology (AREA)
Physical Education & Sports Medicine (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Psychology (AREA)
Pregnancy & Childbirth (AREA)
Diabetes (AREA)
Anesthesiology (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Addiction (AREA)
Vascular Medicine (AREA)

PL08860360T 2007-12-06 2008-12-06 Związki organiczne PL2240490T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US1204007P	2007-12-06	2007-12-06
PCT/US2008/013411 WO2009075784A1 (en)	2007-12-06	2008-12-06	Organic compounds
EP08860360.0A EP2240490B1 (en)	2007-12-06	2008-12-06	Organic compounds

Publications (1)

Publication Number	Publication Date
PL2240490T3 true PL2240490T3 (pl)	2014-02-28

Family

ID=40755776

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL08860360T PL2240490T3 (pl)	2007-12-06	2008-12-06	Związki organiczne

Country Status (17)

Country	Link
US (3)	US8273751B2 (pl)
EP (3)	EP2240490B1 (pl)
JP (4)	JP5068857B2 (pl)
KR (2)	KR20120012831A (pl)
CN (7)	CN104370920A (pl)
AU (1)	AU2008335811B2 (pl)
CA (2)	CA2845454C (pl)
DK (1)	DK2240490T3 (pl)
ES (1)	ES2436780T3 (pl)
HK (6)	HK1207627A1 (pl)
HR (1)	HRP20131073T1 (pl)
IL (2)	IL206096A (pl)
MX (1)	MX2010006212A (pl)
PL (1)	PL2240490T3 (pl)
PT (1)	PT2240490E (pl)
SI (1)	SI2240490T1 (pl)
WO (1)	WO2009075784A1 (pl)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
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US9198924B2 (en)	2006-11-13	2015-12-01	Intra-Cellular Therapies, Inc.	Organic compounds
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WO2009073210A1 (en) *	2007-12-06	2009-06-11	Intra-Cellular Therapies, Inc	Organic compounds
US20120070443A1 (en) *	2008-12-02	2012-03-22	University Of Utah Research Foundation	Pde1 as a target therapeutic in heart disease
EA201170772A1 (ru)	2008-12-06	2012-03-30	Интра-Селлулар Терапиз, Инк.	Органические соединения
EA201170771A1 (ru)	2008-12-06	2012-01-30	Интра-Селлулар Терапиз, Инк.	Органические соединения
JP5778582B2 (ja)	2008-12-06	2015-09-16	イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−ＣｅｌｌｕｌａｒＴｈｅｒａｐｉｅｓ，Ｉｎｃ．	有機化合物
WO2010065148A1 (en)	2008-12-06	2010-06-10	Intra-Cellular Therapies, Inc.	Organic compounds
BRPI0922700A2 (pt)	2008-12-06	2015-08-11	Intracellular Therapies Inc	Compostos orgânicos
MX2011005935A (es)	2008-12-06	2011-12-16	Intra Cellular Therapies Inc	Compuestos organicos.
EP2400970A4 (en)	2009-02-25	2012-07-18	Intra Cellular Therapies Inc	PDE-1-HEMMER FOR EYE DRESSING
US9468637B2 (en)	2009-05-13	2016-10-18	Intra-Cellular Therapies, Inc.	Organic compounds
JP6166534B2 (ja)	2009-08-05	2017-07-19	イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−ＣｅｌｌｕｌａｒＴｈｅｒａｐｉｅｓ，Ｉｎｃ．	新規調節タンパク質および阻害剤
JP2013507360A (ja)	2009-10-08	2013-03-04	イントラ−セルラー・セラピーズ・インコーポレイテッド	ホスホジエステラーゼ１−標的トレーサーおよび方法
US9763948B2 (en)	2010-05-31	2017-09-19	Intra-Cellular Therapies, Inc.	PDE1 inhibitory compounds and methods
US9371327B2 (en)	2010-05-31	2016-06-21	Intra-Cellular Therapies, Inc.	PDE1 inhibitor compounds
US9434730B2 (en)	2010-05-31	2016-09-06	Intra-Cellular Therapies, Inc.	PDE1 inhibitor compounds
TW201206937A (en)	2010-05-31	2012-02-16	Intra Cellular Therapies Inc	Organic compounds
WO2012171016A1 (en)	2011-06-10	2012-12-13	Intra-Cellular Therapies, Inc.	Organic compounds
CA2877146C (en)	2012-06-18	2020-10-20	Dart Neuroscience (Cayman) Ltd	Substituted thiophene- and furan-fused azolopyrimidine-5-(6h)-one compounds
AR091507A1 (es) *	2012-06-21	2015-02-11	Intra Cellular Therapies Inc	SALES DE (6aR,9aS)-5,6a,7,8,9,9a-HEXAHIDRO-5-METIL-3-(FENILAMINO)-2-((4-(6-FLUOROPIRIDIN-2-IL)FENIL)METIL)-CICLOPENT[4,5]IMIDAZO[1,2-a]PIRAZOLO[4,3-e]PIRIMIDIN-4(2H)-ONA
WO2014127331A1 (en)	2013-02-17	2014-08-21	Intra-Cellular Therapies, Inc.	Novel uses
US9545406B2 (en) *	2013-03-15	2017-01-17	Intra-Cellular Therapies, Inc.	Method of treating a CNS injury with a PDE1 inhibitor
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EP3091983B1 (en)	2014-01-08	2019-10-02	Intra-Cellular Therapies, Inc.	Pharmaceutical compositions comprising a pde-1 inhibitor and a pde-2 inhibitor
US9884872B2 (en)	2014-06-20	2018-02-06	Intra-Cellular Therapies, Inc.	Organic compounds
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DK3177627T3 (da)	2014-08-07	2019-10-21	Intra Cellular Therapies Inc	Imidazo[1,2-a]-pyrazolo[4,3-e]-pyrimidin-4-on-derivater med pde1-hæmmende aktivitet
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KR102590848B1 (ko)	2016-12-28	2023-10-19	다트 뉴로사이언스, 엘엘씨	Pde2 억제제로서 치환된 피라졸로피리미디논 화합물
ES2902365T3 (es)	2017-11-27	2022-03-28	Dart Neuroscience Llc	Compuestos de furanopirimidina sustituidos como inhibidores de PDE1
JP7401442B2 (ja)	2018-01-31	2023-12-19	イントラ－セルラー・セラピーズ・インコーポレイテッド	新規使用
KR20210013214A (ko)	2018-05-25	2021-02-03	인트라-셀룰라 써래피스, 인코퍼레이티드.	유기 화합물
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2008
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Also Published As

Publication number	Publication date
JP2011506321A (ja)	2011-03-03
CN104370922A (zh)	2015-02-25
US8829008B2 (en)	2014-09-09
CN104402893A (zh)	2015-03-11
IL231674A0 (en)	2014-04-30
AU2008335811B2 (en)	2012-05-17
CA2707349A1 (en)	2009-06-18
IL206096A0 (en)	2010-11-30
US20140357606A1 (en)	2014-12-04
CN104370919A (zh)	2015-02-25
HK1207631A1 (en)	2016-02-05
JP2016190834A (ja)	2016-11-10
JP2012167099A (ja)	2012-09-06
ES2436780T3 (es)	2014-01-07
IL206096A (en)	2014-04-30
US20100273754A1 (en)	2010-10-28
WO2009075784A1 (en)	2009-06-18
HK1207627A1 (en)	2016-02-05
HK1207628A1 (en)	2016-02-05
EP2939676A1 (en)	2015-11-04
JP5068857B2 (ja)	2012-11-07
KR101227738B1 (ko)	2013-01-29
US20120238589A1 (en)	2012-09-20
CN104370920A (zh)	2015-02-25
CN101970444A (zh)	2011-02-09
US9403836B2 (en)	2016-08-02
HK1207629A1 (en)	2016-02-05
AU2008335811A1 (en)	2009-06-18
KR20100102138A (ko)	2010-09-20
HK1208218A1 (en)	2016-02-26
PT2240490E (pt)	2013-12-09
CA2707349C (en)	2014-05-27
CN104370921A (zh)	2015-02-25
DK2240490T3 (da)	2013-12-16
EP2240490A4 (en)	2011-06-15
HK1207630A1 (en)	2016-02-05
SI2240490T1 (sl)	2014-02-28
EP2240490A1 (en)	2010-10-20
MX2010006212A (es)	2010-08-10
KR20120012831A (ko)	2012-02-10
EP2698160A3 (en)	2014-07-23
EP2240490B1 (en)	2013-09-04
CA2845454C (en)	2017-02-07
CA2845454A1 (en)	2009-06-18
JP5536135B2 (ja)	2014-07-02
CN104370918A (zh)	2015-02-25
EP2698160A2 (en)	2014-02-19
HRP20131073T1 (hr)	2014-01-31
JP2014148534A (ja)	2014-08-21
US8273751B2 (en)	2012-09-25

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IL210976A0 (en)	2011-04-28	Organic compounds
IL213315A0 (en)	2011-07-31	Organic compounds
IL213311A0 (en)	2011-07-31	Organic compounds
IL213313A0 (en)	2011-07-31	Organic compounds
IL213312A0 (en)	2011-07-31	Organic compounds
IL213316A0 (en)	2011-07-31	Organic compounds
IL213314A0 (en)	2011-07-31	Organic compounds
IL210118A0 (en)	2011-02-28	Organic compounds
IL209726A0 (en)	2011-02-28	Organic compounds
IL210836A0 (en)	2011-04-28	Organic compounds
IL206233A0 (en)	2010-12-30	Organic compounds
ZA201003929B (en)	2011-03-30	Organic compounds
ZA201002336B (en)	2011-04-28	Organic compounds
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GB0705931D0 (en)	2007-05-09	Organic compounds
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GB0713860D0 (en)	2007-08-29	Organic compounds
GB0709015D0 (en)	2007-06-20	Organic compounds