PL2263751T3 - Związki izoksazolowe do leczenia raków przewodu pokarmowego - Google Patents

Związki izoksazolowe do leczenia raków przewodu pokarmowego

Info

Publication number
PL2263751T3
PL2263751T3 PL10174276T PL10174276T PL2263751T3 PL 2263751 T3 PL2263751 T3 PL 2263751T3 PL 10174276 T PL10174276 T PL 10174276T PL 10174276 T PL10174276 T PL 10174276T PL 2263751 T3 PL2263751 T3 PL 2263751T3
Authority
PL
Poland
Prior art keywords
treatment
gastrointestinal cancers
isoxazole compound
isoxazole
compound
Prior art date
Application number
PL10174276T
Other languages
English (en)
Inventor
Patrick Chene
Carlos Garcia-Echeverria
Michael Rugaard Jensen
Cornelia Quadt
Thomas Radimerski
Joseph Schoepfer
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL2263751T3 publication Critical patent/PL2263751T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
PL10174276T 2007-10-12 2008-10-10 Związki izoksazolowe do leczenia raków przewodu pokarmowego PL2263751T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07118421 2007-10-12
EP08836801.4A EP2209529B1 (en) 2007-10-12 2008-10-10 Isoxazole compound for the treatment of breast cancer
EP10174276.5A EP2263751B1 (en) 2007-10-12 2008-10-10 Isoxazole compound for the treatment of gastrointestinal cancers

Publications (1)

Publication Number Publication Date
PL2263751T3 true PL2263751T3 (pl) 2014-12-31

Family

ID=38952098

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10174276T PL2263751T3 (pl) 2007-10-12 2008-10-10 Związki izoksazolowe do leczenia raków przewodu pokarmowego

Country Status (19)

Country Link
US (6) US20100210650A1 (pl)
EP (3) EP2209529B1 (pl)
JP (2) JP5800504B2 (pl)
KR (4) KR20100075902A (pl)
CN (2) CN101795728A (pl)
AU (1) AU2008309562B2 (pl)
BR (1) BRPI0818559A2 (pl)
CA (1) CA2700795C (pl)
CL (1) CL2008003005A1 (pl)
ES (1) ES2500920T3 (pl)
MA (1) MA31765B1 (pl)
MX (1) MX2010003988A (pl)
PL (1) PL2263751T3 (pl)
PT (1) PT2263751E (pl)
RU (1) RU2491938C2 (pl)
TN (1) TN2010000139A1 (pl)
TW (1) TW200922595A (pl)
WO (1) WO2009047323A2 (pl)
ZA (1) ZA201001546B (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2017119219A (ru) * 2011-10-14 2018-11-02 Новартис Аг 2-карбоксамид циклоамино производные мочевины в комбинации с ингибиторами hsp90 для лечения пролиферативных заболеваний
BR112015021846A2 (pt) * 2013-03-15 2017-07-18 Novartis Ag biomarcador
US10300026B2 (en) * 2015-08-24 2019-05-28 Shanxi Yabao Health Products Co., Ltd. Use of dihydroxyacetone in preparation of anti-cancer medicaments
KR102653960B1 (ko) * 2020-07-23 2024-04-03 의료법인 성광의료재단 암 치료를 위한 면역체크포인트 억제제의 병용 요법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003282512A1 (en) * 2002-10-22 2004-05-13 The Government Of The United States Of America, Represented By The Secretary, Dept. Of Health And Human Services Methods of reducing the activity of and reducing the concentration of a mutant kit protein
KR101166749B1 (ko) 2003-02-11 2012-07-27 베르날리스(캠브리지)리미티드 열쇼크 단백질 저해제로서의 이소옥사졸 화합물
US20050054625A1 (en) * 2003-05-30 2005-03-10 Kosan Biosciences, Inc. Method for treating diseases using HSP90-inhibiting agents in combination with nuclear export inhibitors
US20070027150A1 (en) * 2005-04-14 2007-02-01 Bellamacina Cornelia R 2-Amino-quinazolin-5-ones
US20070105862A1 (en) * 2005-11-10 2007-05-10 Milan Bruncko Heat-shock protein binders
ES2384906T3 (es) * 2007-03-01 2012-07-13 Novartis Ag Mesilato de etilamida del ácido 5-(2,4-dihidroxi-5-isopropil-fenil)-4-(4-morfolin-4-il-metil-fenil)-isoxazol-3-carboxílico, hidratos y polimorfos del mismo y formulaciones que comprenden estas formas

Also Published As

Publication number Publication date
BRPI0818559A2 (pt) 2015-04-22
MX2010003988A (es) 2010-04-27
AU2008309562B2 (en) 2012-01-19
JP5800504B2 (ja) 2015-10-28
US20100210650A1 (en) 2010-08-19
US20160045513A1 (en) 2016-02-18
KR20100075902A (ko) 2010-07-05
WO2009047323A2 (en) 2009-04-16
CA2700795C (en) 2017-03-07
KR20170124642A (ko) 2017-11-10
EP2263751B1 (en) 2014-07-09
US20160220576A1 (en) 2016-08-04
EP2263751A1 (en) 2010-12-22
CN101795728A (zh) 2010-08-04
US20120083496A1 (en) 2012-04-05
CN104306377A (zh) 2015-01-28
JP2011500535A (ja) 2011-01-06
KR20160143877A (ko) 2016-12-14
ZA201001546B (en) 2010-10-27
EP2209529B1 (en) 2018-09-19
TN2010000139A1 (en) 2011-09-26
CL2008003005A1 (es) 2009-05-08
RU2491938C2 (ru) 2013-09-10
MA31765B1 (fr) 2010-10-01
US20120214813A1 (en) 2012-08-23
ES2500920T3 (es) 2014-10-01
EP2209529A2 (en) 2010-07-28
EP3427797A1 (en) 2019-01-16
RU2010118458A (ru) 2011-11-20
KR101841872B1 (ko) 2018-03-26
AU2008309562A1 (en) 2009-04-16
US20140288075A1 (en) 2014-09-25
KR20160040738A (ko) 2016-04-14
CA2700795A1 (en) 2009-04-16
JP2014156475A (ja) 2014-08-28
WO2009047323A3 (en) 2009-11-12
TW200922595A (en) 2009-06-01
PT2263751E (pt) 2014-09-10

Similar Documents

Publication Publication Date Title
PT2303021T (pt) Compostos para tratamento do cancro
IL200090A0 (en) Composition for treatment of undifferentiated-type of gastric cancer
HUE038452T2 (hu) Gyomor és bélrendszeri gyulladások kezelésére szolgáló kompozíciók
SI2391650T1 (sl) Postopki za zdravljenje protina
IL248204A0 (en) Combined treatment of tumors expressing 38cd
IL232406A (en) Therapeutic isoxazole compounds
EP2049139A4 (en) TREATMENT OF TUMORS EXPRESSING RAS
ZA201003425B (en) 5-cyano-thienopyridines for the treatment of tumors
PL3199180T3 (pl) Przeciwciała przeciwko epha3 do leczenia guzów litych
PL2022504T3 (pl) Maść do leczenia hemoroidów
EP2352501A4 (en) COMPOUNDS FOR THE TREATMENT OF OSTEOPOROSIS AND CANCERS
IL210066A0 (en) Novel ortho-aminoanilides for the treatment of cancer
PT3388111T (pt) Composto organoarsénico para o tratamento de cancro
PT2263751E (pt) Composto de isoxazole para o tratamento de cancros gastrointestinais
PL2252302T3 (pl) Kompozycja do leczenia zapalenia kości i stawów
TWI346662B (en) Oxadiazole compounds
IL201318A0 (en) Use of hdac inhibitors for the treatment of gastrointestinal cancers
HK1143556A (en) Isoxazole compound for the treatment of cancer
HK1140142A (en) Use of hdac inhibitors for the treatment of gastrointestinal cancers
GB0719613D0 (en) The treatment of pruritis
GB0817857D0 (en) Compounds for the treatment of neoplasia
GB0819536D0 (en) Compounds for the treatment of neoplasia
GB0604114D0 (en) Combinations for the treatment of cancer
GB0609981D0 (en) Novel compounds
PL2214677T3 (pl) Kompozycje do leczenia zapalenia przewodu pokarmowego