PL2276725T3 - Nowe kompleksy rutenu jako katalizatory reakcji metatezy - Google Patents

Nowe kompleksy rutenu jako katalizatory reakcji metatezy

Info

Publication number
PL2276725T3
PL2276725T3 PL09730174T PL09730174T PL2276725T3 PL 2276725 T3 PL2276725 T3 PL 2276725T3 PL 09730174 T PL09730174 T PL 09730174T PL 09730174 T PL09730174 T PL 09730174T PL 2276725 T3 PL2276725 T3 PL 2276725T3
Authority
PL
Poland
Prior art keywords
catalysts
metathesis reactions
ruthenium complexes
new ruthenium
new
Prior art date
Application number
PL09730174T
Other languages
English (en)
Inventor
Kurt Puentener
Michelangelo Scalone
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PL2276725T3 publication Critical patent/PL2276725T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/18—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides
    • C07C235/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/18—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides
    • C07C235/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/16—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0046—Ruthenium compounds

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Peptides Or Proteins (AREA)
PL09730174T 2008-04-11 2009-03-30 Nowe kompleksy rutenu jako katalizatory reakcji metatezy PL2276725T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08154367 2008-04-11
EP09730174A EP2276725B1 (en) 2008-04-11 2009-03-30 New ruthenium complexes as catalysts for metathesis reactions
PCT/EP2009/053711 WO2009124853A1 (en) 2008-04-11 2009-03-30 New ruthenium complexes as catalysts for metathesis reactions

Publications (1)

Publication Number Publication Date
PL2276725T3 true PL2276725T3 (pl) 2012-11-30

Family

ID=40578497

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09730174T PL2276725T3 (pl) 2008-04-11 2009-03-30 Nowe kompleksy rutenu jako katalizatory reakcji metatezy

Country Status (15)

Country Link
US (1) US7939668B2 (pl)
EP (1) EP2276725B1 (pl)
JP (1) JP5531008B2 (pl)
KR (1) KR101216900B1 (pl)
CN (1) CN101970396B (pl)
AU (1) AU2009235569B2 (pl)
BR (1) BRPI0909205A2 (pl)
CA (1) CA2719531C (pl)
DK (1) DK2276725T3 (pl)
ES (1) ES2388994T3 (pl)
IL (1) IL208034A (pl)
MX (1) MX2010010660A (pl)
PL (1) PL2276725T3 (pl)
SI (1) SI2276725T1 (pl)
WO (1) WO2009124853A1 (pl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2010011306A (es) 2008-04-15 2010-11-09 Intermune Inc Nuevos inhibidores macrociclicos de la replicacion del virus de la hepatitis c.
AR075584A1 (es) 2009-02-27 2011-04-20 Intermune Inc COMPOSICIONES TERAPEUTICAS QUE COMPRENDEN beta-D-2'-DESOXI-2'-FLUORO-2'-C-METILCITIDINA Y UN DERIVADO DE ACIDO ISOINDOL CARBOXILICO Y SUS USOS. COMPUESTO.
ES2449298T3 (es) * 2009-05-07 2014-03-19 F. Hoffmann-La Roche Ag Proceso para la preparación de catalizadores complejos de metátesis de rutenio
WO2011079439A1 (en) * 2009-12-30 2011-07-07 Zannan Scitech Co., Ltd. Highly active metathesis catalysts selective for romp and rcm reactions
US8592618B2 (en) * 2010-01-08 2013-11-26 Zannan Scitech Co., Ltd. Highly active metathesis catalysts selective for ROMP and RCM reactions
US20130204026A1 (en) 2010-03-24 2013-08-08 Materia, Inc. Method for in-situ formation of metathesis catalysts
US8633280B2 (en) * 2011-03-30 2014-01-21 Zannan Scitech Co., Ltd Methods of modifying polymers with highly active and selective metathesis catalysts
WO2012167171A2 (en) * 2011-06-03 2012-12-06 Massachusetts Institute Of Technology Z-selective ring-closing metathesis reactions
PL220408B1 (pl) * 2011-09-26 2015-10-30 Inst Chemii Organicznej Polskiej Akademii Nauk Kompleks rutentu, sposób jego wytwarzania oraz zastosowanie
JP6032272B2 (ja) 2012-03-16 2016-11-24 日本ゼオン株式会社 開環メタセシス重合体水素化物の製造方法及び樹脂組成物
JP6092379B2 (ja) * 2012-06-29 2017-03-08 アペイロン シンセシス エス アー 金属錯体、その適用、及びメタセシス反応の実施方法
CN107233920A (zh) * 2016-03-29 2017-10-10 上海东杰高分子材料有限公司 一种钌络合物催化剂
CN106939026B (zh) * 2017-03-09 2020-03-20 上海克琴科技有限公司 一种钌金属烯烃复分解催化剂的制备及其应用
CN109280074A (zh) * 2017-07-20 2019-01-29 歌礼药业（浙江）有限公司 丹诺瑞韦钠晶体及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2811507A (en) * 1954-10-20 1957-10-29 Koppers Co Inc Alkenylaryloxyacetamides
US5936100A (en) * 1996-12-16 1999-08-10 Studiengesellschaft Kohle Mbh Synthesis of functionalized macrocycles by ring closing metathesis
EP0921129A1 (en) * 1997-12-03 1999-06-09 Studiengesellschaft Kohle mbH Highly active cationic ruthenium and osmium complexes for olefin metathesis reactions
CA2521835A1 (en) * 2003-04-10 2004-10-21 Boehringer Ingelheim International Gmbh Process for the preparation of macrocyclic compounds by ruthenium complex catalysed metathesis reaction
EP1629000B1 (en) 2003-04-16 2009-02-18 Bristol-Myers Squibb Company Macrocyclic isoquinoline peptide inhibitors of hepatitis c virus
DE10335416A1 (de) * 2003-08-02 2005-02-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Metathesekatalysatoren
HRP20130098T1 (hr) 2003-10-14 2013-02-28 F. Hoffmann - La Roche Ag MAKROCIKLIÄŚKE KARBOKSILNE KISELINE I ACILSULFONAMIDNI SPOJEVI KAO INHIBITORI REPLIKACIJE HCV-a
US7491794B2 (en) * 2003-10-14 2009-02-17 Intermune, Inc. Macrocyclic compounds as inhibitors of viral replication
BRPI0509467A (pt) * 2004-03-30 2007-09-11 Intermune Inc compostos macrocìclicos como inibidores de replicação viral
WO2006033851A1 (en) * 2004-09-17 2006-03-30 Boehringer Ingelheim International, Gmbh Ring-closing metathesis process in supercritical fluid
KR101294467B1 (ko) 2005-07-25 2013-09-09 인터뮨, 인크. Ｃ형 간염 바이러스 복제의 신규 거대고리형 억제제
DE102006044699A1 (de) 2006-09-22 2008-04-03 Bayerische Motoren Werke Ag Tragrohr einer Instrumententafel eines Kraftfahrzeugs

Also Published As

Publication number Publication date
CA2719531C (en) 2013-03-19
US20090275714A1 (en) 2009-11-05
US7939668B2 (en) 2011-05-10
WO2009124853A1 (en) 2009-10-15
AU2009235569B2 (en) 2012-03-29
EP2276725B1 (en) 2012-07-04
SI2276725T1 (sl) 2012-09-28
IL208034A (en) 2014-09-30
EP2276725A1 (en) 2011-01-26
JP2011522778A (ja) 2011-08-04
JP5531008B2 (ja) 2014-06-25
CN101970396B (zh) 2014-06-18
CA2719531A1 (en) 2009-10-15
KR101216900B1 (ko) 2012-12-28
CN101970396A (zh) 2011-02-09
KR20100127822A (ko) 2010-12-06
AU2009235569A1 (en) 2009-10-15
ES2388994T3 (es) 2012-10-22
BRPI0909205A2 (pt) 2015-08-11
MX2010010660A (es) 2010-10-25
DK2276725T3 (da) 2012-08-20
IL208034A0 (en) 2010-12-30

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