PL2279205T3 - Modyfikowane białka rusztowania w postaci stefiny A - Google Patents

Modyfikowane białka rusztowania w postaci stefiny A

Info

Publication number
PL2279205T3
PL2279205T3 PL09742378T PL09742378T PL2279205T3 PL 2279205 T3 PL2279205 T3 PL 2279205T3 PL 09742378 T PL09742378 T PL 09742378T PL 09742378 T PL09742378 T PL 09742378T PL 2279205 T3 PL2279205 T3 PL 2279205T3
Authority
PL
Poland
Prior art keywords
scaffold proteins
modified stefin
stefin
modified
scaffold
Prior art date
Application number
PL09742378T
Other languages
English (en)
Inventor
Ferrigno Paul Ko
Elisenda Gendra
Original Assignee
Avacta Life Sciences Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avacta Life Sciences Limited filed Critical Avacta Life Sciences Limited
Publication of PL2279205T3 publication Critical patent/PL2279205T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8139Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
PL09742378T 2008-04-18 2009-04-16 Modyfikowane białka rusztowania w postaci stefiny A PL2279205T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0807065.8A GB0807065D0 (en) 2008-04-18 2008-04-18 Novel scaffolds
EP09742378.4A EP2279205B1 (en) 2008-04-18 2009-04-16 Modified Stefin A scaffold proteins

Publications (1)

Publication Number Publication Date
PL2279205T3 true PL2279205T3 (pl) 2017-04-28

Family

ID=39472316

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09742378T PL2279205T3 (pl) 2008-04-18 2009-04-16 Modyfikowane białka rusztowania w postaci stefiny A

Country Status (12)

Country Link
US (2) US8853131B2 (pl)
EP (1) EP2279205B1 (pl)
JP (1) JP5688362B2 (pl)
CN (1) CN102056942B (pl)
CA (1) CA2757513C (pl)
DK (1) DK2279205T3 (pl)
ES (1) ES2602602T3 (pl)
GB (1) GB0807065D0 (pl)
HU (1) HUE031800T2 (pl)
PL (1) PL2279205T3 (pl)
PT (1) PT2279205T (pl)
WO (1) WO2009136182A1 (pl)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0807065D0 (en) * 2008-04-18 2008-05-21 Univ Leeds Novel scaffolds
CA3067107C (en) 2010-06-03 2022-07-12 Idexx Laboratories, Inc. Markers for renal disease
GB201302597D0 (en) 2013-02-14 2013-04-03 Univ Leeds Novel Synthetic Proteins
US20190119357A1 (en) * 2015-07-23 2019-04-25 Modernatx, Inc. Messenger ribonucleic acids for the production of intracellular binding polypeptides and methods of use thereof
WO2017127750A1 (en) 2016-01-22 2017-07-27 Modernatx, Inc. Messenger ribonucleic acids for the production of intracellular binding polypeptides and methods of use thereof
WO2018098352A2 (en) 2016-11-22 2018-05-31 Jun Oishi Targeting kras induced immune checkpoint expression
CA3048486A1 (en) 2017-01-04 2018-07-12 Complete Genomics, Inc. Stepwise sequencing by non-labeled reversible terminators or natural nucleotides
JP7070914B2 (ja) * 2017-01-20 2022-05-18 国立大学法人埼玉大学 抗体-多糖結合体及びそれを用いた高感度免疫測定方法
WO2018211126A1 (en) 2017-05-19 2018-11-22 Philip Morris Products S.A. Diagnostic test for distinguishing the smoking status of a subject
GB201710973D0 (en) * 2017-07-07 2017-08-23 Avacta Life Sciences Ltd Scaffold proteins
EP3801634A4 (en) * 2018-06-04 2022-11-30 Trustees of Tufts College TUMOR MICRO ENVIRONMENT ACTIVATED DRUG-BINDER CONJUGATES AND USES THEREOF
CN108959846B (zh) * 2018-07-03 2021-09-14 南昌立德生物技术有限公司 一种计算机辅助先导药物优化设计的亲和自由能分解算法
US20220155309A1 (en) 2019-02-27 2022-05-19 National University Corporation Tokyo Medical And Dental University Fusion protein of antigen-binding protein and fluorescent protein or fluorescence-labeled tag protein
CA3156704A1 (en) * 2019-10-09 2021-04-15 Edward Fritsch Multi-domain protein vaccine
AU2020367510B2 (en) * 2019-10-16 2025-06-26 Lg Chem, Ltd. Neonatal Fc receptor binding AFFIMERs
GB202101299D0 (en) 2020-06-09 2021-03-17 Avacta Life Sciences Ltd Diagnostic polypetides and methods
TW202221030A (zh) * 2020-07-30 2022-06-01 英商阿法克塔生命科學有限公司 血清白蛋白結合多肽
WO2022073493A1 (en) 2020-10-09 2022-04-14 Bgi Shenzhen Co., Ltd. Methods and compositions for bioluminescence-based sequencing
WO2023153876A1 (ko) 2022-02-10 2023-08-17 주식회사 아피셀테라퓨틱스 Cd40l에 특이적으로 결합하는 스테핀 a 단백질 변이체 및 이의 용도
FR3147278A1 (fr) 2023-03-31 2024-10-04 Avacta Life Sciences Limited Polypeptides de liaison au tnfr2 et procedes d'utilisation
EP4689072A1 (en) * 2023-03-31 2026-02-11 AffyXell Therapeutics Co., Ltd. Genetically modified cells into which a nucleic acid encoding a stefin a protein variants specifically binding to tnfr2 or a fusion protein comprising the same has been introduced, and uses thereof
FR3147292A1 (fr) 2023-03-31 2024-10-04 Affyxell Therapeutics Co., Ltd. Cellules genetiquement modifiees dans lesquelles un acide nucleique codant pour des variantes de la proteine stefine a se liant specifiquement au tnfr2 ou une proteine de fusion comprenant celle-ci a ete introduite, et leurs utilisations
CN121013863A (zh) 2023-03-31 2025-11-25 艾菲赛尔治疗株式会社 Tnfr2结合多肽及使用方法
WO2025068426A1 (en) 2023-09-26 2025-04-03 Cytovation ASA Treatment of cancers associated with beta-catenin
GB202403780D0 (en) 2024-03-15 2024-05-01 Avacta Life Sciences Ltd Polypeptides and methods for detecting and quantifying small molecules

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1904529B1 (en) * 2005-06-10 2010-08-11 Medical Research Council Use of stefin a as a scaffold protein
GB0807065D0 (en) * 2008-04-18 2008-05-21 Univ Leeds Novel scaffolds

Also Published As

Publication number Publication date
CA2757513C (en) 2022-11-15
US20110053796A1 (en) 2011-03-03
US8853131B2 (en) 2014-10-07
JP5688362B2 (ja) 2015-03-25
US20160024184A1 (en) 2016-01-28
DK2279205T3 (en) 2016-12-05
ES2602602T3 (es) 2017-02-21
PT2279205T (pt) 2016-11-17
US9447170B2 (en) 2016-09-20
HUE031800T2 (en) 2017-08-28
GB0807065D0 (en) 2008-05-21
EP2279205B1 (en) 2016-08-17
WO2009136182A1 (en) 2009-11-12
CA2757513A1 (en) 2009-11-12
EP2279205A1 (en) 2011-02-02
JP2011520786A (ja) 2011-07-21
CN102056942A (zh) 2011-05-11
CN102056942B (zh) 2017-05-31

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