PL2288612T3 - Modulatory receptora GABAA - Google Patents
Modulatory receptora GABAAInfo
- Publication number
- PL2288612T3 PL2288612T3 PL09726806T PL09726806T PL2288612T3 PL 2288612 T3 PL2288612 T3 PL 2288612T3 PL 09726806 T PL09726806 T PL 09726806T PL 09726806 T PL09726806 T PL 09726806T PL 2288612 T3 PL2288612 T3 PL 2288612T3
- Authority
- PL
- Poland
- Prior art keywords
- receptor modulators
- gabaa receptor
- gabaa
- modulators
- receptor
- Prior art date
Links
- 102000027484 GABAA receptors Human genes 0.000 title 1
- 108091008681 GABAA receptors Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0800759 | 2008-04-04 | ||
| EP09726806.4A EP2288612B1 (en) | 2008-04-04 | 2009-04-02 | Gabaa receptor modulators |
| PCT/SE2009/000176 WO2009123537A1 (en) | 2008-04-04 | 2009-04-02 | GABAa RECEPTOR MODULATORS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2288612T3 true PL2288612T3 (pl) | 2015-12-31 |
Family
ID=41135804
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL09726806T PL2288612T3 (pl) | 2008-04-04 | 2009-04-02 | Modulatory receptora GABAA |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8809355B2 (pl) |
| EP (1) | EP2288612B1 (pl) |
| CN (1) | CN102046627B (pl) |
| CA (1) | CA2720464C (pl) |
| PL (1) | PL2288612T3 (pl) |
| WO (1) | WO2009123537A1 (pl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7236458B2 (ja) * | 2017-12-19 | 2023-03-09 | ガバテール アクチエボラグ | トリアゾロキナゾリノンの合成 |
| CN116806147A (zh) * | 2020-10-06 | 2023-09-26 | 加巴瑟公司 | 三唑并喹唑啉酮化合物的脂质制剂 |
| WO2025128933A1 (en) * | 2023-12-14 | 2025-06-19 | The Brigham And Women's Hospital, Inc. | Gaba-a receptor positive allosteric modulators and methods of use thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6268496B1 (en) * | 1990-10-31 | 2001-07-31 | Neurogen Corporation | Certain imidazoquinoxalines: a new class of GABA brain receptor ligands |
| EP0760819B1 (en) * | 1994-05-24 | 2000-07-19 | F. Hoffmann-La Roche Ag | Tricyclic dicarbonyl derivatives |
| US5955465A (en) * | 1996-03-22 | 1999-09-21 | Neurogen Corporation | 1,2,4-triazolo 4,3-c!quinazolin-3-ones and 1,2,4-triazolo 4,3-c!quinazolin-3-thiones |
| KR20000029548A (ko) * | 1996-07-25 | 2000-05-25 | 더블유. 지. 콜 | 가바수용체에대한리간드로서의치환된트리아졸로-피리다진유도체 |
| GB9813006D0 (en) * | 1998-06-16 | 1998-08-12 | Merck Sharp & Dohme | Therapeutic agents |
| AU2001275014A1 (en) * | 2000-05-30 | 2001-12-11 | Neurogen Corporation | Imidazoloisoquinolines |
-
2009
- 2009-04-02 WO PCT/SE2009/000176 patent/WO2009123537A1/en not_active Ceased
- 2009-04-02 CN CN2009801202864A patent/CN102046627B/zh active Active
- 2009-04-02 US US12/936,050 patent/US8809355B2/en active Active
- 2009-04-02 EP EP09726806.4A patent/EP2288612B1/en active Active
- 2009-04-02 PL PL09726806T patent/PL2288612T3/pl unknown
- 2009-04-02 CA CA2720464A patent/CA2720464C/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US8809355B2 (en) | 2014-08-19 |
| CA2720464A1 (en) | 2009-10-08 |
| CN102046627A (zh) | 2011-05-04 |
| CA2720464C (en) | 2017-05-02 |
| EP2288612A4 (en) | 2011-04-13 |
| EP2288612B1 (en) | 2015-07-29 |
| WO2009123537A1 (en) | 2009-10-08 |
| EP2288612A1 (en) | 2011-03-02 |
| US20110092525A1 (en) | 2011-04-21 |
| CN102046627B (zh) | 2013-09-04 |
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