PL2297359T3 - Profile ekspresji genów do przewidywania skutków raka piersi - Google Patents

Profile ekspresji genów do przewidywania skutków raka piersi

Info

Publication number
PL2297359T3
PL2297359T3 PL09770678T PL09770678T PL2297359T3 PL 2297359 T3 PL2297359 T3 PL 2297359T3 PL 09770678 T PL09770678 T PL 09770678T PL 09770678 T PL09770678 T PL 09770678T PL 2297359 T3 PL2297359 T3 PL 2297359T3
Authority
PL
Poland
Prior art keywords
gene expression
breast cancer
expression profiles
cancer outcomes
predict breast
Prior art date
Application number
PL09770678T
Other languages
English (en)
Other versions
PL2297359T4 (pl
Inventor
Charles M Perou
Joel S Parker
James Stephen Marron
Andrew Nobel
Philip S Bernard
Matthew Ellis
Elaine Mardis
Torsten O Nielsen
Maggie Cheang
Original Assignee
Univ North Carolina Chapel Hill
Univ Utah Res Found
Univ Washington
British Columbia Cancer Agency Branch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ North Carolina Chapel Hill, Univ Utah Res Found, Univ Washington, British Columbia Cancer Agency Branch filed Critical Univ North Carolina Chapel Hill
Publication of PL2297359T4 publication Critical patent/PL2297359T4/pl
Publication of PL2297359T3 publication Critical patent/PL2297359T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Data Mining & Analysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Bioethics (AREA)
  • Artificial Intelligence (AREA)
  • Databases & Information Systems (AREA)
  • Epidemiology (AREA)
  • Evolutionary Computation (AREA)
  • Public Health (AREA)
  • Software Systems (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PL09770678T 2008-05-30 2009-06-01 Profile ekspresji genów do przewidywania skutków raka piersi PL2297359T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5750808P 2008-05-30 2008-05-30
PCT/US2009/045820 WO2009158143A1 (en) 2008-05-30 2009-06-01 Gene expression profiles to predict breast cancer outcomes
EP09770678.2A EP2297359B1 (en) 2008-05-30 2009-06-01 Gene expression profiles to predict breast cancer outcomes

Publications (2)

Publication Number Publication Date
PL2297359T4 PL2297359T4 (pl) 2014-07-31
PL2297359T3 true PL2297359T3 (pl) 2014-07-31

Family

ID=41202871

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09770678T PL2297359T3 (pl) 2008-05-30 2009-06-01 Profile ekspresji genów do przewidywania skutków raka piersi

Country Status (13)

Country Link
US (7) US9631239B2 (pl)
EP (2) EP2664679B1 (pl)
JP (3) JP5740302B2 (pl)
AU (1) AU2009262894B2 (pl)
CA (1) CA2725760C (pl)
CY (1) CY1114993T1 (pl)
DK (1) DK2297359T3 (pl)
ES (2) ES2650610T3 (pl)
HR (1) HRP20140140T1 (pl)
PL (1) PL2297359T3 (pl)
PT (1) PT2297359E (pl)
SI (1) SI2297359T1 (pl)
WO (1) WO2009158143A1 (pl)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2580969Y2 (ja) 1993-11-01 1998-09-17 株式会社イナックス 便器自動洗浄装置
JP5740302B2 (ja) 2008-05-30 2015-06-24 ザ ユニバーシティー オブ ノースカロライナ アット チャペル ヒル 乳癌の予後を予測するための遺伝子発現プロフィール
ES2546089T3 (es) * 2009-01-23 2015-09-18 Bergen Teknologioverforing As Métodos para determinar un pronóstico de supervivencia para una paciente con cáncer de mama
US9771618B2 (en) 2009-08-19 2017-09-26 Bioarray Genetics, Inc. Methods for treating breast cancer
WO2011061568A1 (en) * 2009-11-22 2011-05-26 Azure Vault Ltd. Automatic chemical assay classification
ES2525382T3 (es) * 2010-03-31 2014-12-23 Sividon Diagnostics Gmbh Método para la predicción de recurrencia del cáncer de mama bajo tratamiento endocrino
WO2012106718A2 (en) * 2011-02-04 2012-08-09 Bioarray Therapeutics, Inc. Methods of using gene expression signatures to select a method of treatment, predict prognosis, survival, and/or predict response to treatment
JP5971769B2 (ja) * 2011-03-15 2016-08-17 ザ ユニバーシティー オブ ノースカロライナ アット チャペル ヒル アントラサイクリン療法を用いて乳癌を処置する方法
PT2737081T (pt) 2011-07-28 2016-12-23 Sividon Diagnostics Gmbh Método para prever a resposta a quimioterapia num doente que sofre de ou em risco de desenvolver cancro de mama recorrente
PL2739153T3 (pl) 2011-07-29 2019-04-30 Medivation Prostate Therapeutics Llc Leczenie raka sutka
EP2786140A4 (en) * 2011-11-28 2015-10-28 Nat Res Council Canada PACLITAXEL REACTION MARKERS FOR CANCER
EP2785873A4 (en) * 2011-11-30 2015-11-11 Univ North Carolina METHOD FOR THE TREATMENT OF BREAST CANCER WITH TAXAN THERAPY
JP6325530B2 (ja) * 2012-05-22 2018-05-16 ナノストリング テクノロジーズ，インコーポレイティド Ｎａｎｏ４６遺伝子、及び乳癌転帰を予測する方法
US9939533B2 (en) 2012-05-30 2018-04-10 Lucerno Dynamics, Llc System and method for the detection of gamma radiation from a radioactive analyte
US9002438B2 (en) 2012-05-30 2015-04-07 Lucerno Dynamics System for the detection of gamma radiation from a radioactive analyte
US9890430B2 (en) 2012-06-12 2018-02-13 Washington University Copy number aberration driven endocrine response gene signature
CA2877378A1 (en) * 2012-06-29 2014-01-03 Nanostring Technologies, Inc. Methods of treating breast cancer with gemcitabine therapy
CN102719547B (zh) * 2012-07-02 2013-10-09 厦门大学 检测her2基因表达水平的实时荧光定量pcr试剂盒
EP4219765B1 (en) 2012-08-16 2024-12-18 Veracyte SD, Inc. Prostate cancer prognosis using biomarkers
EP2888391A4 (en) * 2012-08-24 2016-09-14 Univ Utah Res Found COMPOSITIONS AND METHODS RELATING TO BLOOD-BASED BIOMARKERS FOR BREAST CANCER
WO2014071218A2 (en) * 2012-11-02 2014-05-08 University Of Utah Research Foundation Biomarkers for breast cancer and methods of using same
US20140154681A1 (en) * 2012-11-12 2014-06-05 Nanostring Technologies, Inc. Methods to Predict Breast Cancer Outcome
DK2951317T3 (en) 2013-02-01 2018-01-15 Sividon Diagnostics Gmbh PROCEDURE FOR PREDICTING THE BENEFIT OF INCLUSING TAXAN IN A CHEMOTHERAPY PLAN FOR BREAST CANCER PATIENTS
CA2912445A1 (en) * 2013-05-13 2014-11-20 Nanostring Technologies, Inc. Methods to predict risk of recurrence in node-positive early breast cancer
EP2959021B1 (en) * 2013-08-19 2018-08-08 BioNTech Diagnostics GmbH Methods and kits for the molecular subtyping of tumors
CN105473735A (zh) 2013-08-19 2016-04-06 拜恩科技诊断有限责任公司 用于肿瘤分子亚型分型的方法和试剂盒
EP3036712A4 (en) * 2013-08-20 2017-04-19 The Ohio State Innovation Foundation Methods for predicting prognosis
EP3044332A1 (en) * 2013-09-09 2016-07-20 British Columbia Cancer Agency Branch Methods and kits for predicting outcome and methods and kits for treating breast cancer with radiation therapy
KR101560880B1 (ko) 2013-10-15 2015-10-19 이화여자대학교 산학협력단 유방암의 예후 판단을 위한 정보를 제공하는 방법
US10628748B2 (en) 2013-12-03 2020-04-21 University Of Massachusetts System and methods for predicting probable relationships between items
US10684290B2 (en) * 2014-02-18 2020-06-16 Dignity Health LKB1 related diagnostics and treatments of cancer
WO2015179312A1 (en) * 2014-05-17 2015-11-26 The Regents Of The University Of California Centromere/kinetochore protein genes for cancer diagnosis, prognosis and treatment selection
ES2910099T3 (es) 2014-11-21 2022-05-11 Nanostring Technologies Inc Secuenciación sin enzimas y sin amplificación
WO2016085841A1 (en) 2014-11-24 2016-06-02 Nanostring Technologies, Inc. Methods and apparatuses for gene purification and imaging
US20160160293A1 (en) * 2014-12-09 2016-06-09 King's College London Breast cancer treatment with taxane therapy
ES2748005T3 (es) 2014-12-12 2020-03-12 Medivation Prostate Therapeutics Llc Método para predecir la respuesta a agentes terapéuticos de cáncer de mama y método de tratamiento de cáncer de mama
CN107430133B (zh) * 2015-02-27 2020-03-27 延世大学校产学协力团 用于测定乳腺癌预后以及是否使用化疗的装置和方法
US11174518B2 (en) * 2015-10-05 2021-11-16 Cedars-Sinai Medical Center Method of classifying and diagnosing cancer
EP3387168B1 (en) 2015-12-07 2021-05-12 Ontario Institute for Cancer Research (OICR) Gene signature of residual risk following endocrine treatment in early breast cancer
CA3022377A1 (en) 2016-04-29 2017-11-02 Board Of Regents, The University Of Texas System Targeted measure of transcriptional activity related to hormone receptors
EP3458601B1 (en) 2016-05-16 2023-07-05 Nanostring Technologies, Inc. Methods for detecting target nucleic acids in a sample
US10934590B2 (en) 2016-05-24 2021-03-02 Wisconsin Alumni Research Foundation Biomarkers for breast cancer and methods of use thereof
US11414708B2 (en) 2016-08-24 2022-08-16 Decipher Biosciences, Inc. Use of genomic signatures to predict responsiveness of patients with prostate cancer to post-operative radiation therapy
WO2018074865A2 (ko) * 2016-10-21 2018-04-26 서울대학교병원 유방암 예후 예측용 조성물 및 방법
KR102476709B1 (ko) 2016-11-21 2022-12-09 나노스트링 테크놀로지스, 인크. 화학적 조성물 및 이것을 사용하는 방법
ES2674327B2 (es) * 2016-11-28 2018-12-17 Geicam - Grupo Español De Investigacion En Cancer De Mama CES: un índice quimioendocrino basado en PAM50 para el cáncer de mama con receptores hormonales positivos con un riesgo intermedio de recidiva
KR101874716B1 (ko) * 2016-12-14 2018-07-04 연세대학교 산학협력단 유방암 분자아형 분류방법 및 이를 이용한 유방암 분자아형 분류 디바이스
US20200017913A1 (en) * 2017-03-02 2020-01-16 President And Fellows Of Harvard College Methods and systems for predicting treatment responses in subjects
AU2018230784A1 (en) * 2017-03-09 2019-10-10 Decipher Biosciences, Inc. Subtyping prostate cancer to predict response to hormone therapy
CA3066930A1 (en) * 2017-06-16 2018-12-20 Nantomics, Llc Prognostic indicators of poor outcomes in praegnant metastatic breast cancer cohort
US12497660B2 (en) 2017-08-04 2025-12-16 Veracyte SD, Inc. Use of immune cell-specific gene expression for prognosis of prostate cancer and prediction of responsiveness to radiation therapy
WO2019051266A2 (en) 2017-09-08 2019-03-14 Myriad Genetics, Inc. METHOD OF USING BIOMARKERS AND CLINICAL VARIABLES TO PREDICT THE INTEREST OF CHEMOTHERAPY
IT201700109459A1 (it) * 2017-09-29 2019-03-29 Univ Degli Studi Di Perugia Metodo per effettuare prognosi del cancro della mammella, kit ed uso di questi
EP3707724A1 (en) * 2017-11-08 2020-09-16 Koninklijke Philips N.V. Method for simultaneous multivariate feature selection, feature generation, and sample clustering
WO2019165366A1 (en) * 2018-02-23 2019-08-29 Beth Israel Deaconess Medical Center Drug efficacy evaluations
KR102893736B1 (ko) 2018-05-14 2025-11-28 브루커 스페이셜 바이올로지, 인크. 화학 조성물 및 이의 사용 방법
KR101966589B1 (ko) * 2018-06-20 2019-04-05 연세대학교 산학협력단 유방암 분자아형 분류방법 및 이를 이용한 유방암 분자아형 분류 디바이스
US20220002815A1 (en) * 2018-11-04 2022-01-06 Pfs Genomics, Inc. Methods and genomic classifiers for prognosis of breast cancer and predicting benefit from adjuvant radiotherapy
CN109801680B (zh) * 2018-12-03 2023-02-28 广州中医药大学(广州中医药研究院) 基于tcga数据库的肿瘤转移复发预测方法及系统
WO2020178399A1 (en) 2019-03-05 2020-09-10 Norwegian University Of Science And Technology (Ntnu) Breast cancer signature genes
CN109913551A (zh) * 2019-03-26 2019-06-21 深圳大学 乳腺癌分型的核酸组合物、乳腺癌分型试剂盒及其使用方法
US12357250B2 (en) 2019-04-02 2025-07-15 Lucerno Dynamics, Llc System and method of using temporal measurements of localized radiation to estimate the magnitude, location, and volume of radioactive material in the body
CN111508555A (zh) * 2020-04-15 2020-08-07 淮南师范学院 一组用于度量生物分子集的网络拓扑学特性的方法
KR102507489B1 (ko) * 2020-12-24 2023-03-08 가톨릭대학교 산학협력단 진단 분류 장치 및 방법
CN112626218A (zh) * 2021-01-07 2021-04-09 浙江科技学院 一种用于预测胰腺癌转移风险的基因表达分类器、体外诊断试剂盒
CN112735529B (zh) * 2021-01-18 2024-07-30 中国医学科学院肿瘤医院 乳腺癌预后模型的构建方法及应用方法、电子设备
RU2762317C1 (ru) * 2021-02-24 2021-12-17 Федеральное государственное бюджетное научное учреждение "Томский национальный исследовательский медицинский центр Российской академии наук" (Томский НИМЦ) Способ прогнозирования статуса рецептора эпидермального фактора роста her2/neu в основном опухолевом узле у больных раком молочной железы
US20240344138A1 (en) * 2021-03-25 2024-10-17 Feng Biosciences, Inc Targeted therapies in cancer
CN114300139A (zh) * 2022-01-13 2022-04-08 澳门科技大学 一种乳腺癌预后模型的构建及其应用方法和存储介质
JP2025530330A (ja) * 2022-06-21 2025-09-11 バイオベンチャーズ・リミテッド・ライアビリティ・カンパニー 保存組織からの腫瘍の分子サブタイプ分類法
CN115144599B (zh) * 2022-09-05 2023-01-06 西湖大学 蛋白组合在制备对儿童甲状腺癌进行预后分层的试剂盒中的用途及其试剂盒、系统
US12308126B1 (en) * 2024-02-13 2025-05-20 Institut Curie Device and method for predicting a relapse of a cancer for a patient
EP4621073A1 (en) 2024-03-22 2025-09-24 Istituto Europeo di Oncologia S.r.l. Method for prognosis of breast cancer

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4843155A (en) 1987-11-19 1989-06-27 Piotr Chomczynski Product and process for isolating RNA
US6040138A (en) 1995-09-15 2000-03-21 Affymetrix, Inc. Expression monitoring by hybridization to high density oligonucleotide arrays
US5800992A (en) 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US20040235039A1 (en) 1990-03-20 2004-11-25 Regents Of The University Of California Chromosome-specific staining to detect genetic rearrangements
ATE148889T1 (de) 1991-09-18 1997-02-15 Affymax Tech Nv Verfahren zur synthese der verschiedenen sammlungen von oligomeren
US6025126A (en) 1991-10-28 2000-02-15 Arch Development Corporation Methods and compositions for the detection of chromosomal aberrations
US5384261A (en) 1991-11-22 1995-01-24 Affymax Technologies N.V. Very large scale immobilized polymer synthesis using mechanically directed flow paths
EP1588761A3 (en) 1991-11-22 2005-11-23 Affymetrix, Inc. Method of forming arrays of polymers
US5856174A (en) 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
US5854033A (en) 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
EP0880598A4 (en) 1996-01-23 2005-02-23 Affymetrix Inc RAPID EVALUATION OF NUCLEIC ACID ABUNDANCE DIFFERENCE, WITH A HIGH-DENSITY OLIGONUCLEOTIDE SYSTEM
WO1999023254A1 (en) 1997-10-31 1999-05-14 Affymetrix, Inc. Expression profiles in adult and fetal organs
US6020135A (en) 1998-03-27 2000-02-01 Affymetrix, Inc. P53-regulated genes
AU2004248120B2 (en) 2003-05-28 2009-04-23 Genomic Health, Inc. Gene expression markers for predicting response to chemotherapy
EP2163650B1 (en) 2004-04-09 2015-08-05 Genomic Health, Inc. Gene expression markers for predicting response to chemotherapy
US20080032293A1 (en) 2004-07-15 2008-02-07 The University Of North Carolina At Chapel Hill Housekeeping Genes And Methods For Identifying Same
JP2006141210A (ja) 2004-11-16 2006-06-08 Hitachi Ltd キメラ遺伝子の検出方法
US20090299640A1 (en) 2005-11-23 2009-12-03 University Of Utah Research Foundation Methods and Compositions Involving Intrinsic Genes
WO2007076132A2 (en) 2005-12-23 2007-07-05 Nanostring Technologies, Inc. Compositions comprising oriented, immobilized macromolecules and methods for their preparation
AU2006330830B2 (en) 2005-12-23 2013-01-10 Bruker Spatial Biology, Inc. Nanoreporters and methods of manufacturing and use thereof
US7892740B2 (en) 2006-01-19 2011-02-22 The University Of Chicago Prognosis and therapy predictive markers and methods of use
WO2007147018A1 (en) * 2006-06-14 2007-12-21 Cellpoint Diagnostics, Inc. Analysis of rare cell-enriched samples
US20090239223A1 (en) 2006-07-13 2009-09-24 Siemens Healthcare Diagnostics Inc. Prediction of Breast Cancer Response to Taxane-Based Chemotherapy
EP2155899A2 (en) 2007-04-10 2010-02-24 Nanostring Technologies, Inc. Methods and computer systems for identifying target-specific sequences for use in nanoreporters
US20090105167A1 (en) 2007-10-19 2009-04-23 Duke University Predicting responsiveness to cancer therapeutics
JP5740302B2 (ja) 2008-05-30 2015-06-24 ザ ユニバーシティー オブ ノースカロライナ アット チャペル ヒル 乳癌の予後を予測するための遺伝子発現プロフィール
ES2684317T3 (es) 2008-08-14 2018-10-02 Nanostring Technologies, Inc Nanoinformadores estables
EP3216874A1 (en) 2008-09-05 2017-09-13 TOMA Biosciences, Inc. Methods for stratifying and annotating cancer drug treatment options
WO2010039275A1 (en) 2008-10-03 2010-04-08 Oligonix, Inc. Method, array and system for detecting intergenic fusions
EP2358199A2 (en) 2008-11-02 2011-08-24 Optimata Ltd. Improving cancer therapy by docetaxel and granulocyte colony-stimulating factor (g-csf)
EP2486149B1 (en) 2009-08-06 2015-06-17 John Wayne Cancer Institute Diagnosis of primary and metastatic basal-like breast cancer and other cancer types
EP2507396A4 (en) 2009-12-01 2013-06-19 Precision Therapeutics Inc MULTI-MEDICATION RESPONSE MARKERS FOR BREAST CANCER CELLS
WO2011130495A1 (en) 2010-04-14 2011-10-20 Nuvera Biosciences, Inc. Methods of evaluating response to cancer therapy
JP5971769B2 (ja) 2011-03-15 2016-08-17 ザ ユニバーシティー オブ ノースカロライナ アット チャペル ヒル アントラサイクリン療法を用いて乳癌を処置する方法
US9758834B2 (en) 2011-03-28 2017-09-12 Nanostring Technologies, Inc. Compositions and methods for diagnosing cancer
EP2785873A4 (en) 2011-11-30 2015-11-11 Univ North Carolina METHOD FOR THE TREATMENT OF BREAST CANCER WITH TAXAN THERAPY
JP6325530B2 (ja) 2012-05-22 2018-05-16 ナノストリング テクノロジーズ，インコーポレイティド Ｎａｎｏ４６遺伝子、及び乳癌転帰を予測する方法
CA2877378A1 (en) 2012-06-29 2014-01-03 Nanostring Technologies, Inc. Methods of treating breast cancer with gemcitabine therapy
US20140154681A1 (en) 2012-11-12 2014-06-05 Nanostring Technologies, Inc. Methods to Predict Breast Cancer Outcome
EP3044332A1 (en) 2013-09-09 2016-07-20 British Columbia Cancer Agency Branch Methods and kits for predicting outcome and methods and kits for treating breast cancer with radiation therapy

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