PL2303872T3 - Pochodne izoksazolu i ich zastosowanie jako potencjatorów metabotropowych receptorów glutaminianowych - Google Patents

Pochodne izoksazolu i ich zastosowanie jako potencjatorów metabotropowych receptorów glutaminianowych

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Publication number
PL2303872T3
PL2303872T3 PL09758630T PL09758630T PL2303872T3 PL 2303872 T3 PL2303872 T3 PL 2303872T3 PL 09758630 T PL09758630 T PL 09758630T PL 09758630 T PL09758630 T PL 09758630T PL 2303872 T3 PL2303872 T3 PL 2303872T3
Authority
PL
Poland
Prior art keywords
glutamate receptor
metabotropic glutamate
isoxazole derivatives
receptor potentiators
potentiators
Prior art date
Application number
PL09758630T
Other languages
English (en)
Inventor
Joseph Cacciola
James Empfield
James Folmer
Angela M Hunter
Scott Throner
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of PL2303872T3 publication Critical patent/PL2303872T3/pl

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    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/08—Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound
    • A61B17/083—Clips, e.g. resilient
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    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/08—Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound
    • A61B17/085—Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound with adhesive layer
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    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/10—Surgical instruments, devices or methods for applying or removing wound clamps, e.g. containing only one clamp or staple; Wound clamp magazines
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
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PL09758630T 2008-06-06 2009-06-08 Pochodne izoksazolu i ich zastosowanie jako potencjatorów metabotropowych receptorów glutaminianowych PL2303872T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5948508P 2008-06-06 2008-06-06
PCT/SE2009/050682 WO2009148403A1 (en) 2008-06-06 2009-06-08 Isoxazole derivatives and their use as metabotropic glutamate receptor potentiators
EP09758630.9A EP2303872B1 (en) 2008-06-06 2009-06-08 Isoxazole derivatives and their use as metabotropic glutamate receptor potentiators

Publications (1)

Publication Number Publication Date
PL2303872T3 true PL2303872T3 (pl) 2014-08-29

Family

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Application Number Title Priority Date Filing Date
PL09758630T PL2303872T3 (pl) 2008-06-06 2009-06-08 Pochodne izoksazolu i ich zastosowanie jako potencjatorów metabotropowych receptorów glutaminianowych

Country Status (40)

Country Link
US (4) US7790760B2 (pl)
EP (2) EP2772492B1 (pl)
JP (2) JP5476371B2 (pl)
KR (1) KR20110020797A (pl)
CN (1) CN102105466B (pl)
AR (1) AR072016A1 (pl)
AU (1) AU2009255784B2 (pl)
BR (1) BRPI0913585A2 (pl)
CA (1) CA2726925A1 (pl)
CL (1) CL2010001348A1 (pl)
CO (1) CO6321239A2 (pl)
CR (1) CR11826A (pl)
CU (1) CU23883B1 (pl)
CY (1) CY1115301T1 (pl)
DK (1) DK2303872T3 (pl)
DO (1) DOP2010000375A (pl)
EA (2) EA201300342A1 (pl)
EC (1) ECSP10010662A (pl)
ES (1) ES2469837T3 (pl)
GT (1) GT201000342A (pl)
HK (1) HK1201255A1 (pl)
HN (1) HN2010002582A (pl)
HR (1) HRP20140451T1 (pl)
IL (1) IL209622A0 (pl)
MX (1) MX2010012949A (pl)
MY (1) MY156552A (pl)
NI (3) NI201000209A (pl)
NZ (1) NZ590344A (pl)
PE (1) PE20110028A1 (pl)
PL (1) PL2303872T3 (pl)
PT (1) PT2303872E (pl)
RS (1) RS53392B (pl)
SA (1) SA109300358B1 (pl)
SI (1) SI2303872T1 (pl)
SV (1) SV2010003751A (pl)
TW (3) TWI477499B (pl)
UA (1) UA107649C2 (pl)
UY (1) UY31870A (pl)
WO (1) WO2009148403A1 (pl)
ZA (1) ZA201008611B (pl)

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JP5852666B2 (ja) 2010-11-08 2016-02-03 ジヤンセン・フアーマシユーチカルズ・インコーポレーテツド １，２，４−トリアゾロ［４，３−ａ］ピリジン誘導体およびｍＧｌｕＲ２受容体のポジティブアロステリックモジュレーターとしてのそれらの使用
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JO3367B1 (ar) 2013-09-06 2019-03-13 Janssen Pharmaceutica Nv مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
KR20220038826A (ko) 2014-01-21 2022-03-29 얀센 파마슈티카 엔.브이. 대사 조절형 글루탐산 작동성 수용체 제2아형의 양성 알로스테릭 조절제 또는 오르토스테릭 작동제를 포함하는 조합 및 그 용도
KR20200036063A (ko) 2014-01-21 2020-04-06 얀센 파마슈티카 엔.브이. 대사 조절형 글루탐산 작동성 수용체 제2아형의 양성 알로스테릭 조절제 또는 오르토스테릭 작동제를 포함하는 조합 및 그 용도
WO2015157187A1 (en) 2014-04-06 2015-10-15 Sanford-Burnham Medical Research Institute Metabotropic glutamate receptor positive allosteric modulators (pams) and uses thereof
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