PL2313374T3 - 6-podstawione izochinoliny i izochinolinony - Google Patents

6-podstawione izochinoliny i izochinolinony

Info

Publication number: PL2313374T3
Authority: PL; Poland
Prior art keywords: isoquinolinones; substituted isoquinolines; isoquinolines; substituted
Prior art date: 2008-06-24

Application number

PL09768948T

Other languages

English (en)

Inventor

Oliver Plettenburg

Katrin Lorenz

Matthias Loehn

John Weston

Heinz-Werner Kleemann

Original Assignee

Sanofi Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-06-24

Filing date

2009-06-19

Publication date

2014-03-31

2009-06-19 Application filed by Sanofi Sa filed Critical Sanofi Sa

2014-03-31 Publication of PL2313374T3 publication Critical patent/PL2313374T3/pl

Links

-1 6-substituted isoquinolines Chemical class 0.000 title 1
VDBNYAPERZTOOF-UHFFFAOYSA-N isoquinolin-1(2H)-one Chemical class C1=CC=C2C(=O)NC=CC2=C1 VDBNYAPERZTOOF-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Hematology (AREA)
Neurosurgery (AREA)
Cardiology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Heart & Thoracic Surgery (AREA)
Pulmonology (AREA)
Endocrinology (AREA)
Obesity (AREA)
Pain & Pain Management (AREA)
Ophthalmology & Optometry (AREA)
Urology & Nephrology (AREA)
Immunology (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Reproductive Health (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Gynecology & Obstetrics (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Vascular Medicine (AREA)
AIDS & HIV (AREA)

PL09768948T 2008-06-24 2009-06-19 6-podstawione izochinoliny i izochinolinony PL2313374T3 (pl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
EP08290605		2008-06-24
US15314509P	2009-02-17	2009-02-17
PCT/EP2009/004420 WO2009156099A1 (en)	2008-06-24	2009-06-19	6-substituted isoquinolines and isoquinolinones
EP09768948.3A EP2313374B1 (en)	2008-06-24	2009-06-19	6-substituted isoquinolines and isoquinolinones

Publications (1)

Publication Number	Publication Date
PL2313374T3 true PL2313374T3 (pl)	2014-03-31

Family

ID=40044043

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL09768948T PL2313374T3 (pl)	2008-06-24	2009-06-19	6-podstawione izochinoliny i izochinolinony

Country Status (28)

Country	Link
US (2)	US8399482B2 (pl)
EP (1)	EP2313374B1 (pl)
JP (1)	JP5714485B2 (pl)
KR (1)	KR101607090B1 (pl)
CN (1)	CN102131785B (pl)
AR (1)	AR072280A1 (pl)
AU (1)	AU2009262516B8 (pl)
BR (1)	BRPI0914735A2 (pl)
CA (1)	CA2728128C (pl)
CO (1)	CO6321249A2 (pl)
CR (1)	CR11830A (pl)
DK (1)	DK2313374T3 (pl)
DO (1)	DOP2010000392A (pl)
ES (1)	ES2436531T3 (pl)
HR (1)	HRP20131041T1 (pl)
IL (1)	IL210115A (pl)
MA (1)	MA32399B1 (pl)
MX (1)	MX2010013974A (pl)
MY (1)	MY153615A (pl)
PE (1)	PE20110054A1 (pl)
PL (1)	PL2313374T3 (pl)
PT (1)	PT2313374E (pl)
RU (1)	RU2528229C2 (pl)
SI (1)	SI2313374T1 (pl)
SV (1)	SV2010003771A (pl)
TW (1)	TWI480265B (pl)
UY (1)	UY31926A (pl)
WO (1)	WO2009156099A1 (pl)

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EP4422626A1 (en)	2021-10-30	2024-09-04	Aneuryst, Inc	Treatments for disturbed cerebral homeostasis
IL318082A (en)	2022-08-01	2025-02-01	Valo Health Inc	Process for preparing 1-(2H)-ISOQUINOLINONE-type materials modified at position 6, and intermediates obtained in the process

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2009
- 2009-06-19 MY MYPI2010005676A patent/MY153615A/en unknown
- 2009-06-19 CN CN200980132931.4A patent/CN102131785B/zh not_active Expired - Fee Related
- 2009-06-19 WO PCT/EP2009/004420 patent/WO2009156099A1/en not_active Ceased
- 2009-06-19 DK DK09768948.3T patent/DK2313374T3/da active
- 2009-06-19 CA CA2728128A patent/CA2728128C/en not_active Expired - Fee Related
- 2009-06-19 MX MX2010013974A patent/MX2010013974A/es active IP Right Grant
- 2009-06-19 EP EP09768948.3A patent/EP2313374B1/en active Active
- 2009-06-19 JP JP2011515174A patent/JP5714485B2/ja not_active Expired - Fee Related
- 2009-06-19 HR HRP20131041AT patent/HRP20131041T1/hr unknown
- 2009-06-19 ES ES09768948.3T patent/ES2436531T3/es active Active
- 2009-06-19 PL PL09768948T patent/PL2313374T3/pl unknown
- 2009-06-19 AU AU2009262516A patent/AU2009262516B8/en not_active Ceased
- 2009-06-19 RU RU2011102376/04A patent/RU2528229C2/ru not_active IP Right Cessation
- 2009-06-19 SI SI200930784T patent/SI2313374T1/sl unknown
- 2009-06-19 PT PT97689483T patent/PT2313374E/pt unknown
- 2009-06-19 KR KR1020107028931A patent/KR101607090B1/ko not_active Expired - Fee Related
- 2009-06-19 BR BRPI0914735A patent/BRPI0914735A2/pt not_active IP Right Cessation
- 2009-06-19 PE PE2010001192A patent/PE20110054A1/es not_active Application Discontinuation
- 2009-06-22 AR ARP090102284A patent/AR072280A1/es unknown
- 2009-06-22 TW TW098120766A patent/TWI480265B/zh not_active IP Right Cessation
- 2009-06-22 UY UY0001031926A patent/UY31926A/es not_active Application Discontinuation
2010
- 2010-12-07 CR CR11830A patent/CR11830A/es not_active Application Discontinuation
- 2010-12-16 US US12/970,376 patent/US8399482B2/en active Active
- 2010-12-17 MA MA33437A patent/MA32399B1/fr unknown
- 2010-12-20 IL IL210115A patent/IL210115A/en not_active IP Right Cessation
- 2010-12-20 DO DO2010000392A patent/DOP2010000392A/es unknown
- 2010-12-20 SV SV2010003771A patent/SV2010003771A/es unknown
- 2010-12-21 CO CO10160326A patent/CO6321249A2/es not_active Application Discontinuation
2012
- 2012-12-14 US US13/715,111 patent/US20130109715A1/en not_active Abandoned

Also Published As

Publication number	Publication date
MX2010013974A (es)	2011-01-14
CR11830A (es)	2011-04-04
MA32399B1 (fr)	2011-06-01
US8399482B2 (en)	2013-03-19
US20110190339A1 (en)	2011-08-04
JP2011525510A (ja)	2011-09-22
WO2009156099A8 (en)	2010-03-11
HK1158643A1 (en)	2012-07-20
AU2009262516B8 (en)	2014-01-30
CN102131785A (zh)	2011-07-20
MY153615A (en)	2015-02-27
AU2009262516A1 (en)	2009-12-30
TWI480265B (zh)	2015-04-11
IL210115A (en)	2016-07-31
PT2313374E (pt)	2013-11-29
SI2313374T1 (sl)	2013-12-31
RU2011102376A (ru)	2012-07-27
UY31926A (es)	2010-01-29
ES2436531T3 (es)	2014-01-02
CO6321249A2 (es)	2011-09-20
DK2313374T3 (da)	2013-12-16
AR072280A1 (es)	2010-08-18
CN102131785B (zh)	2014-10-29
AU2009262516B2 (en)	2014-01-09
RU2528229C2 (ru)	2014-09-10
KR20110019753A (ko)	2011-02-28
PE20110054A1 (es)	2011-02-15
EP2313374B1 (en)	2013-09-18
IL210115A0 (en)	2011-02-28
EP2313374A1 (en)	2011-04-27
SV2010003771A (es)	2011-03-15
TW201014826A (en)	2010-04-16
AU2009262516A8 (en)	2014-01-30
US20130109715A1 (en)	2013-05-02
BRPI0914735A2 (pt)	2019-09-24
JP5714485B2 (ja)	2015-05-07
WO2009156099A1 (en)	2009-12-30
DOP2010000392A (es)	2011-01-15
HRP20131041T1 (hr)	2013-12-06
CA2728128A1 (en)	2009-12-30
KR101607090B1 (ko)	2016-03-29
CA2728128C (en)	2016-06-07

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