PL2314580T3 - Sposób wytwarzania syntetycznych kannabinoidów - Google Patents

Sposób wytwarzania syntetycznych kannabinoidów

Info

Publication number
PL2314580T3
PL2314580T3 PL10004422T PL10004422T PL2314580T3 PL 2314580 T3 PL2314580 T3 PL 2314580T3 PL 10004422 T PL10004422 T PL 10004422T PL 10004422 T PL10004422 T PL 10004422T PL 2314580 T3 PL2314580 T3 PL 2314580T3
Authority
PL
Poland
Prior art keywords
producing synthetic
synthetic cannabinoids
cannabinoids
producing
synthetic
Prior art date
Application number
PL10004422T
Other languages
English (en)
Inventor
Christian Steup
Thomas Herkenroth
Original Assignee
The Health Concept Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Health Concept Gmbh filed Critical The Health Concept Gmbh
Publication of PL2314580T3 publication Critical patent/PL2314580T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/80Dibenzopyrans; Hydrogenated dibenzopyrans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/50Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions decreasing the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/36Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/42Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
PL10004422T 2009-04-30 2010-04-27 Sposób wytwarzania syntetycznych kannabinoidów PL2314580T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102009019322A DE102009019322A1 (de) 2009-04-30 2009-04-30 Verfahren zur Herstellung von Synthetischen Cannabinoiden
EP10004422.1A EP2314580B1 (de) 2009-04-30 2010-04-27 Verfahren zur Herstellung von synthetischen Cannabinoiden

Publications (1)

Publication Number Publication Date
PL2314580T3 true PL2314580T3 (pl) 2016-02-29

Family

ID=42932300

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10004422T PL2314580T3 (pl) 2009-04-30 2010-04-27 Sposób wytwarzania syntetycznych kannabinoidów

Country Status (5)

Country Link
US (1) US20100298579A1 (pl)
EP (1) EP2314580B1 (pl)
DE (1) DE102009019322A1 (pl)
ES (1) ES2554653T3 (pl)
PL (1) PL2314580T3 (pl)

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US9376367B2 (en) 2011-09-29 2016-06-28 The Health Concept Gmbh Cannabinoid carboxylic acids, salts of cannabinoid carboxylic acids, and the production and uses of same
JP6581509B2 (ja) 2013-02-28 2019-09-25 ティーウィノット テクノロジーズ リミテッド 化合物を合成する化学工学プロセス及び装置
EP2842933B1 (de) * 2013-09-03 2015-07-29 Symrise AG Mischungen cannabinoider Verbindungen, deren Herstellung und Verwendung
AU2015308136B2 (en) 2014-08-25 2020-07-09 Teewinot Technologies Limited Apparatus and methods for the simultaneous production of cannabinoid compounds
DK3232808T3 (da) 2014-12-19 2020-06-02 Thc Pharm Gmbh The Health Concept CBD-holdig drik
US20160228385A1 (en) * 2015-02-05 2016-08-11 Colorado Can Llc Purified cbd and cbda, and methods, compositions and products employing cbd or cbda
EP3061450A1 (de) 2015-02-26 2016-08-31 Symrise AG Mischungen cannabinoider Verbindungen, deren Herstellung und Verwendung
US20160250270A1 (en) 2015-02-27 2016-09-01 Ebbu, LLC Compositions comprising combinations of purified cannabinoids, with at least one flavonoid, terpene, or mineral
US20170008869A1 (en) * 2015-07-10 2017-01-12 Noramco, Inc. Process for the production of cannabidiol and delta-9-tetrahydrocannabinol
EP3150264A1 (de) * 2015-09-30 2017-04-05 Bionorica Ethics GmbH Vakuumdestillation zur anreicherung von cbd
EP3455213B1 (en) 2016-05-13 2021-11-24 Symrise AG Method for purifying cannabinoid compounds via simulated moving bed chromatography
US10399920B2 (en) 2016-06-01 2019-09-03 S&B Pharma, Inc. Crystalline form of cannabidiol
US12485129B2 (en) 2016-08-29 2025-12-02 Canopy Growth Corporation Water soluble compositions comprising purified cannabinoids
CA3034004C (en) 2016-08-29 2021-08-03 Canopy Growth Corporation Water soluble compositions comprising purified cannabinoids
US10239808B1 (en) 2016-12-07 2019-03-26 Canopy Holdings, LLC Cannabis extracts
CN106810426B (zh) * 2016-12-29 2020-05-08 暨明医药科技(苏州)有限公司 一种大麻二酚的合成方法
AU2018227544A1 (en) * 2017-03-01 2019-08-29 Canopy Growth Corporation Compositions purposefully selected comprising purified cannabinoids and/or purified terpenes
DK3509638T3 (da) * 2017-06-20 2022-04-11 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd Præparater med cannabidiolsyreestere og anvendelser deraf
AU2018317939B2 (en) * 2017-08-16 2021-06-03 The University Of Sydney Synthesis of phytocannabinoids including a decarboxylation step
EP3461545A1 (de) 2017-09-30 2019-04-03 Bionorica Ethics GmbH Kurzwegdestillation im vakuum zur anreicherung von naturstoffen
CA3089994A1 (en) 2018-01-31 2019-08-08 Canopy Holdings, LLC Hemp powder
BR102018002843A2 (pt) * 2018-02-09 2019-08-27 Prati, Donaduzzi & Cia Ltda composição farmacêutica e uso da mesma
US11192870B2 (en) * 2018-03-07 2021-12-07 Socati Technologies—Oregon, Llc Continuous isolation of cannabidiol and conversion of cannabidiol to delta 8-tetrahydrocannabinol and delta 9-tetrahydrocannabinol
US11851415B2 (en) * 2018-03-07 2023-12-26 Cleen Technology Inc. Continuous isolation of cannabidiol and cannabinoids and conversion of cannabidiol to delta 8-tetrahydrocannabinol and delta 9-tetrahydrocannabinol
DE102018001959A1 (de) 2018-03-10 2019-09-12 Florian Frey Thermisches Trennverfahren zur Anreicherung von Cannabinoiden
WO2019222459A1 (en) 2018-05-18 2019-11-21 Diverse Biotech, Inc. Cannabinoid preparations and therapeutic uses
WO2020028198A1 (en) 2018-08-03 2020-02-06 Biomass Oil Separation Solutions, Llc Processes and apparatus for extraction of substances and enriched extracts from plant material
CA3119729A1 (en) 2018-10-10 2020-04-16 Treehouse Biotech, Inc. Synthesis of cannabigerol
EP3873451A4 (en) 2018-10-31 2022-08-10 BayMedica, Inc. CANNABINOID ANALOGUES AND METHODS OF PRODUCTION
WO2020117288A1 (en) * 2018-12-07 2020-06-11 Mckinney Jeffrey A Deuterated agonists and methods of use
WO2020176547A1 (en) 2019-02-25 2020-09-03 Ginkgo Bioworks, Inc. Biosynthesis of cannabinoids and cannabinoid precursors
EP3937925A1 (en) * 2019-03-12 2022-01-19 EPM (IP), Inc. Cannabinoid acid ester compositions and uses thereof
US10981850B2 (en) 2019-04-15 2021-04-20 Trustees Of Boston University One-step flow-mediated synthesis of cannabidiol (CBD) and derivatives
KR20220007078A (ko) * 2019-05-10 2022-01-18 베누비아 매뉴팩처링, 엘엘씨 칸나비디올 또는 칸나비디바린의 제조 방법 및 칸나비디올 또는 칸나비디바린 제조의 중간체
CN111943813B (zh) 2019-05-17 2023-04-14 上海特化医药科技有限公司 大麻二酚类化合物的制备方法
US10799546B1 (en) 2019-07-26 2020-10-13 Biomass Oil Separation Solutions, Llc Modular, integrated process and apparatus for extracting, refining and remediating active substances from plant material
MX2022002183A (es) * 2019-08-22 2022-05-24 Epm Group Inc Composiciones de éster de ácido cannabinoide y sus usos.
US11542243B1 (en) 2019-09-26 2023-01-03 FusionFarms, LLC Method of converting delta9-THC to delta10-THC and the purification of the delta10-THC by crystallization
CA3162971A1 (en) * 2019-12-27 2021-07-01 Charles K. Marlowe Preparation of cannabichromene and related cannabinoids
EP4089084A4 (en) * 2020-01-08 2024-03-13 Chengdu Baiyu Pharmaceutical Co., Ltd. Cannabidiol derivative, and preparation method therefor and medical use thereof
US12545694B2 (en) 2020-01-08 2026-02-10 Chengdu Baiyu Pharmaceutical Co., Ltd. Cannabidiol derivatives, preparation method thereof and use thereof
US12391711B2 (en) 2020-01-08 2025-08-19 Chengdu Baiyu Pharmaceutical Co., Ltd. Tetrahydrocannabinol derivatives, preparation method thereof and use thereof
ES2936274T3 (es) 2020-02-21 2023-03-15 Sci Pharmtech Inc Método sin disolvente para preparar cannabinoides
MX2022011832A (es) * 2020-03-31 2023-03-03 Phytotherapeutix Ltd Compuestos terpenofenolicos y su uso.
US20210355097A1 (en) * 2020-05-12 2021-11-18 FinChemica, Inc. Catalytic conversation of cannabidiol and methods thereof
CA3132439A1 (en) * 2020-05-12 2021-11-12 Canopy Growth Corporation Methods of synthesizing cannabigergol, cannabigerolic acid, and analogs thereof
CN111848365A (zh) * 2020-07-16 2020-10-30 云南自由贸易试验区睿之成医药科技有限公司 一种大麻二酚的合成方法
CN113173857B (zh) * 2021-03-09 2023-05-23 昆明理工大学 一种大麻二酚衍生物及其制备方法与应用
CN113603568A (zh) * 2021-07-19 2021-11-05 厦门朝阳生物工程有限公司 一种大麻二酚的制备方法
CA3246935A1 (en) * 2022-01-27 2023-08-03 Citrachem Corp. METHODS OF SYNTHESIZING CANNABIDIOL, ITS DERIVATIVES AND OTHER PHYTOCANNABINOIDS
WO2024028516A1 (en) 2022-08-05 2024-02-08 Salud & Semillas, S.L. CANNABINOID SYNTHESIS STARTING OUT FROM OLIVETOL AND TERPENE IN DICHLOROMETHANE WITH FeCl3 * 6H2O AS CATALYST
EP4642449A1 (en) * 2022-12-29 2025-11-05 Adtech Pharma, Inc. Pharmaceutical compositions comprising nabilone for the treatment of ophthalmic conditions
EP4431169A1 (en) 2023-03-17 2024-09-18 Siegfried AG Method of purifying cannabinoid components from plant extracts

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5342971A (en) 1992-12-29 1994-08-30 The Australian National University Process for the preparation of dibenzo[b,d]pyrans

Also Published As

Publication number Publication date
EP2314580B1 (de) 2015-09-09
ES2554653T3 (es) 2015-12-22
DE102009019322A1 (de) 2010-11-11
EP2314580A1 (de) 2011-04-27
US20100298579A1 (en) 2010-11-25

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