PL2318396T3 - Postać krystaliczna pozakonazolu - Google Patents
Postać krystaliczna pozakonazoluInfo
- Publication number
- PL2318396T3 PL2318396T3 PL09772368T PL09772368T PL2318396T3 PL 2318396 T3 PL2318396 T3 PL 2318396T3 PL 09772368 T PL09772368 T PL 09772368T PL 09772368 T PL09772368 T PL 09772368T PL 2318396 T3 PL2318396 T3 PL 2318396T3
- Authority
- PL
- Poland
- Prior art keywords
- posaconazole
- crystalline form
- crystalline
- Prior art date
Links
- RAGOYPUPXAKGKH-XAKZXMRKSA-N posaconazole Chemical compound O=C1N([C@H]([C@H](C)O)CC)N=CN1C1=CC=C(N2CCN(CC2)C=2C=CC(OC[C@H]3C[C@@](CN4N=CN=C4)(OC3)C=3C(=CC(F)=CC=3)F)=CC=2)C=C1 RAGOYPUPXAKGKH-XAKZXMRKSA-N 0.000 title 1
- 229960001589 posaconazole Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13385208P | 2008-07-03 | 2008-07-03 | |
| EP08159600A EP2141159A1 (en) | 2008-07-03 | 2008-07-03 | A Crystalline form of posaconazole |
| EP09772368.8A EP2318396B9 (en) | 2008-07-03 | 2009-06-25 | A crystalline form of posaconazole |
| PCT/EP2009/057975 WO2010000668A1 (en) | 2008-07-03 | 2009-06-25 | A crystalline form of posaconazole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2318396T3 true PL2318396T3 (pl) | 2013-03-29 |
Family
ID=39951578
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL09772368T PL2318396T3 (pl) | 2008-07-03 | 2009-06-25 | Postać krystaliczna pozakonazolu |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US8435998B2 (pl) |
| EP (2) | EP2141159A1 (pl) |
| KR (1) | KR101639456B1 (pl) |
| CN (1) | CN102066363B (pl) |
| AU (1) | AU2009265848B2 (pl) |
| BR (1) | BRPI0915714A2 (pl) |
| CA (1) | CA2728170C (pl) |
| DK (1) | DK2318396T5 (pl) |
| ES (1) | ES2397592T3 (pl) |
| HR (1) | HRP20130026T2 (pl) |
| IL (1) | IL209196A (pl) |
| MX (1) | MX2010014041A (pl) |
| PL (1) | PL2318396T3 (pl) |
| RS (1) | RS52673B (pl) |
| SI (1) | SI2318396T1 (pl) |
| WO (1) | WO2010000668A1 (pl) |
| ZA (1) | ZA201008019B (pl) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2130540A1 (en) | 2008-06-02 | 2009-12-09 | Sandoz AG | Pharmaceutical compositions containing a crystalline form of posaconazole |
| EP2141159A1 (en) | 2008-07-03 | 2010-01-06 | Sandoz AG | A Crystalline form of posaconazole |
| EP2451805A1 (en) * | 2009-07-09 | 2012-05-16 | Sandoz AG | A crystalline form of posaconazole |
| RU2585683C2 (ru) | 2010-05-19 | 2016-06-10 | Сандоз Аг | Очистка позаконазола и промежуточных продуктов для синтеза позаконазола |
| EP2571847B1 (en) * | 2010-05-19 | 2016-09-21 | Sandoz AG | Process for the preparation of chiral hydrazides |
| US9040539B2 (en) | 2010-05-19 | 2015-05-26 | Sandoz Ag | Process for the preparation of chiral triazolones |
| CN102892762B (zh) | 2010-05-19 | 2016-04-20 | 桑多斯股份公司 | 制备泊沙康唑中间体 |
| CN103635465A (zh) | 2011-06-16 | 2014-03-12 | 桑多斯股份公司 | 制备手性化合物的方法 |
| US20150164890A1 (en) * | 2012-06-14 | 2015-06-18 | Sandoz Ag | Pharmaceutical compositions comprising crystalline posaconazole |
| WO2015011224A1 (en) * | 2013-07-25 | 2015-01-29 | Sandoz Ag | Improved process for the preparation of crystalline form iv of posaconazole |
| ITMI20132118A1 (it) * | 2013-12-18 | 2015-06-19 | Djada Pharmaceutical Sa | Una forma cristallina di posaconazolo |
| ITMI20132117A1 (it) * | 2013-12-18 | 2015-06-19 | Djada Pharmaceutical Sa | Una forma cristallina di posaconazolo |
| ITMI20132115A1 (it) * | 2013-12-18 | 2015-06-19 | Djada Pharmaceutical Sa | Una forma cristallina di posaconazolo |
| ITMI20132114A1 (it) * | 2013-12-18 | 2015-06-19 | Djada Pharmaceutical Sa | Una forma cristallina di posaconazolo |
| DE102014203040A1 (de) | 2014-02-19 | 2015-08-20 | Carl Zeiss Smt Gmbh | Beleuchtungssystem einer mikrolithographischen Projektionsbelichtungsanlage und Verfahren zum Betreiben eines solchen |
| CN104370894A (zh) * | 2014-10-21 | 2015-02-25 | 江苏恒盛药业有限公司 | 无定型泊沙康唑的制备工艺 |
| CN105622590B (zh) * | 2014-10-30 | 2019-08-20 | 上海美悦生物科技发展有限公司 | 一种泊沙康唑的晶型vi及其制备方法 |
| PL3331501T3 (pl) | 2015-08-08 | 2020-03-31 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Preparat o zwiększonej odporności na warunki przewodu pokarmowego zawierający pozakonazol |
| EP4424308A3 (en) | 2016-02-26 | 2024-12-04 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Gastro-resistant formulation containing posaconazole and a polymeric precipitation inhibitor |
| WO2017032908A1 (en) | 2016-07-08 | 2017-03-02 | Synthon B.V. | Pharmaceutical composition comprising amorphous posaconazole |
| KR102567090B1 (ko) * | 2016-11-28 | 2023-08-17 | 셀릭스 바이오 프라이빗 리미티드 | 곰팡이 감염의 치료를 위한 조성물 및 방법 |
| TR201620462A2 (tr) | 2016-12-31 | 2018-07-23 | Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi | POSAKONAZOL İÇEREN FARMASÖTİK BİLEŞİMLER ve ÜRETİM YÖNTEMİ |
| CN106883221A (zh) * | 2017-04-17 | 2017-06-23 | 兰州大学 | 一种无定形泊沙康唑及其制备方法 |
| CN107625729A (zh) * | 2017-09-29 | 2018-01-26 | 重庆华邦制药有限公司 | 泊沙康唑口服混悬液及其制备方法 |
| WO2021022103A1 (en) * | 2019-07-31 | 2021-02-04 | The Regents Of The University Of Michigan | Cocrystals of posaconazole, methods of making and using same |
| GB201917867D0 (en) | 2019-12-06 | 2020-01-22 | Pulmocide Ltd | Polymorphs |
| WO2022034232A1 (en) | 2020-08-13 | 2022-02-17 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Gastro-resistant high-strength formulation containing posaconazole |
| EP4091604B1 (en) | 2021-11-25 | 2024-04-03 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Granules containing posaconazole |
| EP4181883B1 (en) | 2021-11-25 | 2025-11-19 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Granules containing posaconazole |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4533254A (en) | 1981-04-17 | 1985-08-06 | Biotechnology Development Corporation | Apparatus for forming emulsions |
| DE3544983A1 (de) | 1985-12-19 | 1987-06-25 | Hoechst Ag | Antimykotisch wirksamer nagellack |
| IL112081A (en) | 1993-12-21 | 2001-08-26 | Schering Plough Corp | Tetrahydrofuran derivatives, their preparation and antifungal pharmaceutical compositions containing them |
| US5625064A (en) | 1995-04-19 | 1997-04-29 | Schering Corporation | Process for the preparation of triazolones |
| IL118464A (en) | 1995-06-02 | 2000-08-13 | Schering Corp | (2R-cis)-4-¬4-¬4-¬4¬¬-5-(2',4 dihalophenyl)-tetrahydro-5-(1-H-1,2,4,triazol-1-yl-methyl)furan-3-yl(methoxy¾phenyl¾-1-piperazinyl¬phenyl2,4,dihydro2¬(5)-1-ethyl-2-(5)hydroxy propyl¾-3H-1,2,4-triazol-3-one and pharmaceutical compositions comprising them |
| US5834472A (en) | 1996-05-24 | 1998-11-10 | Schering Corporation | Antifungal composition with enhanced bioavailability |
| US5972381A (en) | 1996-06-28 | 1999-10-26 | Schering Corporation | Solid solution of an antifungal agent with enhanced bioavailability |
| CO4970829A1 (es) * | 1997-10-07 | 2000-11-07 | Schering Corp | Polimorfo antifungico cristalino |
| US6713481B1 (en) | 1997-10-17 | 2004-03-30 | David R. Andrews | Crystalline antifungal polymorph |
| WO2002080678A1 (en) | 2001-04-03 | 2002-10-17 | Schering Corporation | Antifungal composition with enhanced bioavailability |
| US7563748B2 (en) | 2003-06-23 | 2009-07-21 | Cognis Ip Management Gmbh | Alcohol alkoxylate carriers for pesticide active ingredients |
| CN1988887A (zh) | 2004-05-28 | 2007-06-27 | 先灵公司 | 包含泊沙康唑的注射用药物混悬剂 |
| RU2346996C2 (ru) | 2004-06-29 | 2009-02-20 | ЮРОПИЭН НИКЕЛЬ ПиЭлСи | Усовершенствованное выщелачивание основных металлов |
| US7930013B2 (en) | 2005-06-29 | 2011-04-19 | Compumedics Limited | Sensor assembly with conductive bridge |
| EP2130540A1 (en) | 2008-06-02 | 2009-12-09 | Sandoz AG | Pharmaceutical compositions containing a crystalline form of posaconazole |
| EP2141159A1 (en) | 2008-07-03 | 2010-01-06 | Sandoz AG | A Crystalline form of posaconazole |
| WO2011000020A1 (en) | 2009-06-12 | 2011-01-06 | Sbc Research Pty Ltd | Enhanced method of detection |
| EP2451805A1 (en) | 2009-07-09 | 2012-05-16 | Sandoz AG | A crystalline form of posaconazole |
-
2008
- 2008-07-03 EP EP08159600A patent/EP2141159A1/en not_active Withdrawn
-
2009
- 2009-06-25 CN CN200980123512.4A patent/CN102066363B/zh not_active Expired - Fee Related
- 2009-06-25 HR HRP20130026AT patent/HRP20130026T2/hr unknown
- 2009-06-25 ES ES09772368T patent/ES2397592T3/es active Active
- 2009-06-25 BR BRPI0915714A patent/BRPI0915714A2/pt not_active Application Discontinuation
- 2009-06-25 CA CA2728170A patent/CA2728170C/en not_active Expired - Fee Related
- 2009-06-25 DK DK09772368.8T patent/DK2318396T5/da active
- 2009-06-25 WO PCT/EP2009/057975 patent/WO2010000668A1/en not_active Ceased
- 2009-06-25 PL PL09772368T patent/PL2318396T3/pl unknown
- 2009-06-25 EP EP09772368.8A patent/EP2318396B9/en active Active
- 2009-06-25 KR KR1020107028674A patent/KR101639456B1/ko not_active Expired - Fee Related
- 2009-06-25 MX MX2010014041A patent/MX2010014041A/es active IP Right Grant
- 2009-06-25 US US12/993,351 patent/US8435998B2/en not_active Expired - Fee Related
- 2009-06-25 AU AU2009265848A patent/AU2009265848B2/en not_active Ceased
- 2009-06-25 SI SI200930468T patent/SI2318396T1/sl unknown
- 2009-06-25 RS RS20130006A patent/RS52673B/sr unknown
-
2010
- 2010-11-08 IL IL209196A patent/IL209196A/en active IP Right Grant
- 2010-11-09 ZA ZA2010/08019A patent/ZA201008019B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2009265848A1 (en) | 2010-01-07 |
| ES2397592T9 (es) | 2013-08-30 |
| WO2010000668A1 (en) | 2010-01-07 |
| BRPI0915714A2 (pt) | 2015-10-27 |
| US8435998B2 (en) | 2013-05-07 |
| EP2141159A1 (en) | 2010-01-06 |
| EP2318396B9 (en) | 2013-05-29 |
| EP2318396A1 (en) | 2011-05-11 |
| DK2318396T3 (da) | 2013-02-04 |
| CA2728170A1 (en) | 2010-01-07 |
| AU2009265848B2 (en) | 2014-02-20 |
| EP2318396B1 (en) | 2012-10-24 |
| CA2728170C (en) | 2017-02-14 |
| US20110065722A1 (en) | 2011-03-17 |
| ES2397592T3 (es) | 2013-03-08 |
| DK2318396T5 (da) | 2013-09-02 |
| HRP20130026T2 (en) | 2013-10-11 |
| KR101639456B1 (ko) | 2016-07-13 |
| ZA201008019B (en) | 2012-02-29 |
| KR20110025763A (ko) | 2011-03-11 |
| IL209196A0 (en) | 2011-01-31 |
| RS52673B (sr) | 2013-06-28 |
| CN102066363A (zh) | 2011-05-18 |
| HRP20130026T1 (hr) | 2013-02-28 |
| IL209196A (en) | 2015-08-31 |
| MX2010014041A (es) | 2011-03-03 |
| CN102066363B (zh) | 2014-11-05 |
| SI2318396T1 (sl) | 2013-02-28 |
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