PL2322183T3 - Wykorzystanie proleku do podawania doocznego, śródszklistkowego - Google Patents

Wykorzystanie proleku do podawania doocznego, śródszklistkowego

Info

Publication number
PL2322183T3
PL2322183T3 PL10177375T PL10177375T PL2322183T3 PL 2322183 T3 PL2322183 T3 PL 2322183T3 PL 10177375 T PL10177375 T PL 10177375T PL 10177375 T PL10177375 T PL 10177375T PL 2322183 T3 PL2322183 T3 PL 2322183T3
Authority
PL
Poland
Prior art keywords
prodrugs
ocular
intravitreous administration
intravitreous
administration
Prior art date
Application number
PL10177375T
Other languages
English (en)
Inventor
Grégory Lambert
Laura Rabinovich-Guilatt
Original Assignee
Santen Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Sas filed Critical Santen Sas
Publication of PL2322183T3 publication Critical patent/PL2322183T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL10177375T 2006-06-01 2006-06-01 Wykorzystanie proleku do podawania doocznego, śródszklistkowego PL2322183T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11/444,337 US20070281914A1 (en) 2006-06-01 2006-06-01 Use of a steroid prodrug for the treatment of disease of the posterior segment of the eye
US11/444,349 US20070280902A1 (en) 2006-06-01 2006-06-01 Method for treating eye disease or conditions affecting the posterior segment of the eye
EP06290901.5A EP1864667B1 (en) 2006-06-01 2006-06-01 Use of prodrugs for ocular intravitreous administration
EP10177375.2A EP2322183B1 (en) 2006-06-01 2006-06-01 Use of prodrugs for ocular intravitreous administration
EP06290902A EP1864668B1 (en) 2006-06-01 2006-06-01 Use of prodrugs for ocular intravitreous administration

Publications (1)

Publication Number Publication Date
PL2322183T3 true PL2322183T3 (pl) 2015-01-30

Family

ID=39712456

Family Applications (4)

Application Number Title Priority Date Filing Date
PL10177382T PL2319517T3 (pl) 2006-06-01 2006-06-01 Wykorzystanie proleku do podawania doocznego, śródszklistkowego
PL06290902T PL1864668T3 (pl) 2006-06-01 2006-06-01 Wykorzystanie proleku do okulistycznego podawania śródszklistkowego
PL10177375T PL2322183T3 (pl) 2006-06-01 2006-06-01 Wykorzystanie proleku do podawania doocznego, śródszklistkowego
PL06290901T PL1864667T3 (pl) 2006-06-01 2006-06-01 Zastosowanie proleków do podania do ciała szklistego oka

Family Applications Before (2)

Application Number Title Priority Date Filing Date
PL10177382T PL2319517T3 (pl) 2006-06-01 2006-06-01 Wykorzystanie proleku do podawania doocznego, śródszklistkowego
PL06290902T PL1864668T3 (pl) 2006-06-01 2006-06-01 Wykorzystanie proleku do okulistycznego podawania śródszklistkowego

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL06290901T PL1864667T3 (pl) 2006-06-01 2006-06-01 Zastosowanie proleków do podania do ciała szklistego oka

Country Status (14)

Country Link
US (4) US20070280902A1 (pl)
EP (4) EP1864668B1 (pl)
JP (2) JP5284953B2 (pl)
KR (1) KR101408317B1 (pl)
CN (1) CN101553235B (pl)
AU (1) AU2007267079B2 (pl)
CA (1) CA2653902C (pl)
DK (2) DK2319517T3 (pl)
ES (1) ES2399976T3 (pl)
IL (1) IL195626A (pl)
PL (4) PL2319517T3 (pl)
PT (2) PT1864668E (pl)
SI (1) SI1864668T1 (pl)
WO (2) WO2007138113A1 (pl)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1864668B1 (en) 2006-06-01 2012-11-21 Novagali Pharma S.A. Use of prodrugs for ocular intravitreous administration
EP2214646B1 (en) * 2007-10-05 2021-06-23 Wayne State University Dendrimers for sustained release of compounds
EP2229174A1 (en) * 2007-12-04 2010-09-22 Novagali Pharma S.A. Compositions comprising corticosteroid prodrug such as dexamethasone palmitate for the treatment of eye disorders
US9877973B2 (en) 2008-05-12 2018-01-30 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
US9095404B2 (en) 2008-05-12 2015-08-04 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
US10064819B2 (en) 2008-05-12 2018-09-04 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
JP5591226B2 (ja) 2008-05-12 2014-09-17 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション 眼内薬物送達装置および関連する方法
UA116622C2 (uk) 2011-11-11 2018-04-25 Аллерган, Інк. Похідні 4-прегенен-11ss-17-21-тріол-3,20-діону для лікування хвороб очей
AU2013216861B2 (en) * 2012-02-10 2017-05-18 Tlc Biopharmaceuticals, Inc Pharmaceutical compositions to reduce complications of ocular steroid
EP3639854B1 (en) 2017-06-16 2026-01-07 The Doshisha Mtor-inhibitor-containing medicine for treating or preventing fuchs' endothelial corneal dystrophy
WO2019094952A1 (en) 2017-11-10 2019-05-16 The Johns Hopkins University Dendrimer delivery system and methods of use thereof
CN111068071A (zh) * 2018-10-22 2020-04-28 武汉纽福斯生物科技有限公司 基因治疗Leber遗传学视神经病变
PE20240329A1 (es) 2019-06-05 2024-02-27 Regeneron Pharma Dispositivos y metodos para administracion de dosis de precision
PL3871662T3 (pl) * 2020-02-25 2023-11-20 Labomed Pharmaceutical Company S.A. Doustne roztwory zawierające octan fludrokortyzonu
EP4213804A1 (en) 2020-09-16 2023-07-26 Santen SAS Oil-in-water emulsions for intravitreal administration
US12649031B2 (en) 2021-09-08 2026-06-09 Regeneron Pharmaceuticals, Inc. Methods for delivering agents with pre-filled syringes to minimize intraocular inflammation
USD1120314S1 (en) 2022-11-30 2026-03-24 Regeneron Pharmaceuticals, Inc. Dose delivery device
WO2024167694A2 (en) * 2023-02-06 2024-08-15 Celularity Inc. Placental extracellular matrices for ocular delivery of ophthalmic therapeutic agents

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS609726B2 (ja) * 1980-05-15 1985-03-12 株式会社 ミドリ十字 ステロイド製剤
JPS5716818A (en) 1981-04-25 1982-01-28 Green Cross Corp:The Steroid fatty emulsion
AU531588B2 (en) 1981-08-17 1983-09-01 Yoshitomi Pharmaceutical Industries, Ltd. Emulsifying water-insoluble steroid
AU604236B2 (en) 1986-04-28 1990-12-13 Iolab, Inc. Intraocular dosage compositions and method of use
AU4201189A (en) * 1988-08-26 1990-03-23 Alcon Laboratories, Inc. Combination of quinolone antibiotics and steroids for topical ophthalmic use
JPH05132498A (ja) 1991-11-08 1993-05-28 Asahi Glass Co Ltd ステロイド誘導体およびその製剤
IL101241A (en) 1992-03-16 1997-11-20 Yissum Res Dev Co Pharmaceutical or cosmetic composition comprising stabilized oil-in-water type emulsion as carrier
CA2125060C (en) * 1993-07-02 1999-03-30 Henry P. Dabrowski Ophthalmic solution for artificial tears
CA2167818A1 (en) * 1993-08-02 1995-02-09 Robert George Whittaker Therapeutic compound - fatty acid conjugates
ES2094688B1 (es) 1994-08-08 1997-08-01 Cusi Lab Manoemulsion del tipo de aceite en agua, util como vehiculo oftalmico y procedimiento para su preparacion.
EP0878197B1 (en) 1997-05-14 2002-08-21 Senju Pharmaceutical Co., Ltd. Compositions containing difluprednate
JP3410364B2 (ja) 1997-05-14 2003-05-26 千寿製薬株式会社 ジフルプレドナート含有組成物
IL121647A (en) * 1997-08-28 2001-07-24 Pharmateam Dev Ltd Pharmaceutical compositions for the treatment of ocular inflammation comprising dexamethasone palmitate
WO1999016471A1 (en) 1997-10-01 1999-04-08 Wakamoto Pharmaceutical Co., Ltd. O/w emulsion compositions
JP2000212067A (ja) * 1999-01-19 2000-08-02 Towa Yakuhin Kk 薬物含有エマルジョン製剤
EP1441696B1 (en) 2001-11-01 2010-05-19 Yissum Research Development Company Of The Hebrew University Of Jerusalem Method and composition for dry eye treatment
US20040151754A1 (en) * 2002-12-20 2004-08-05 Control Delivery Systems, Inc. Steroid suspensions for intraocular use
US20050009910A1 (en) * 2003-07-10 2005-01-13 Allergan, Inc. Delivery of an active drug to the posterior part of the eye via subconjunctival or periocular delivery of a prodrug
AU2004273610B2 (en) * 2003-09-22 2010-07-01 Onepharm Research & Development Gmbh Prevention and treatment of inflammation-induced and/or immune-mediated bone loss
US20050244469A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Extended therapeutic effect ocular implant treatments
US8119154B2 (en) * 2004-04-30 2012-02-21 Allergan, Inc. Sustained release intraocular implants and related methods
EP1611879B1 (en) * 2004-07-02 2009-08-12 Novagali Pharma SA Use of emulsions for intra- and periocular injection
AU2005271700B2 (en) * 2004-07-12 2010-11-11 Allergan, Inc. Opthalmic compositions and methods for treating ophthalmic conditions
MX2007003968A (es) * 2004-10-01 2008-03-04 Ramscor Inc Composiciones de farmaco de liberacion sostenida convenientemente implantables.
US20060094700A1 (en) * 2004-11-02 2006-05-04 Allergan, Inc. Heat sterilization of a steroid in the presence of phosphate
CA2578176C (en) 2004-11-09 2013-09-24 Novagali Pharma Sa Ophthalmic emulsions containing an immunosuppressive agent
CN1905012A (zh) 2005-07-31 2007-01-31 新科实业有限公司 具有微驱动器的磁头折片组合及其磁盘驱动装置
US8109884B2 (en) * 2005-09-23 2012-02-07 Kitchener Clark Wilson Dynamic metabolism monitoring system
EP1864668B1 (en) 2006-06-01 2012-11-21 Novagali Pharma S.A. Use of prodrugs for ocular intravitreous administration

Also Published As

Publication number Publication date
CN101553235A (zh) 2009-10-07
US8227452B2 (en) 2012-07-24
WO2007138114A1 (en) 2007-12-06
PL1864667T3 (pl) 2014-01-31
CA2653902A1 (en) 2007-12-06
KR20090031373A (ko) 2009-03-25
CN101553235B (zh) 2012-12-05
CA2653902C (en) 2015-03-17
AU2007267079B2 (en) 2013-01-31
SI1864668T1 (sl) 2013-04-30
PL2319517T3 (pl) 2014-01-31
EP1864668B1 (en) 2012-11-21
DK2319517T3 (da) 2013-12-09
IL195626A0 (en) 2009-09-01
EP1864667B1 (en) 2013-09-04
DK1864668T3 (da) 2013-03-04
ES2399976T3 (es) 2013-04-04
AU2007267079A1 (en) 2007-12-06
EP2322183B1 (en) 2014-10-22
IL195626A (en) 2017-05-29
PL1864668T3 (pl) 2013-04-30
JP5284953B2 (ja) 2013-09-11
US20070280995A1 (en) 2007-12-06
US20070281914A1 (en) 2007-12-06
WO2007138113A1 (en) 2007-12-06
PT1864668E (pt) 2013-02-26
HK1110221A1 (en) 2008-07-11
US20070281913A1 (en) 2007-12-06
EP2319517A1 (en) 2011-05-11
JP2009538879A (ja) 2009-11-12
JP5455624B2 (ja) 2014-03-26
KR101408317B1 (ko) 2014-06-17
EP1864667A1 (en) 2007-12-12
EP2322183A1 (en) 2011-05-18
US20070280902A1 (en) 2007-12-06
PT1864667E (pt) 2013-11-18
EP2319517B1 (en) 2013-09-11
HK1110219A1 (en) 2008-07-11
US9192567B2 (en) 2015-11-24
EP1864668A1 (en) 2007-12-12
JP2009538880A (ja) 2009-11-12

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