PL2403645T3 - Mikroprzepływowe, elektrochemiczne urządzenia - Google Patents

Mikroprzepływowe, elektrochemiczne urządzenia

Info

Publication number
PL2403645T3
PL2403645T3 PL10712600T PL10712600T PL2403645T3 PL 2403645 T3 PL2403645 T3 PL 2403645T3 PL 10712600 T PL10712600 T PL 10712600T PL 10712600 T PL10712600 T PL 10712600T PL 2403645 T3 PL2403645 T3 PL 2403645T3
Authority
PL
Poland
Prior art keywords
microfluidic
electrochemical devices
electrochemical
devices
Prior art date
Application number
PL10712600T
Other languages
English (en)
Inventor
Zhihong Nie
Christian Nijhuis
Xin Chen
Andres W. Martinez
Max Narovlyansky
George M. Whitesides
Original Assignee
President And Fellows Of Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by President And Fellows Of Harvard College filed Critical President And Fellows Of Harvard College
Publication of PL2403645T3 publication Critical patent/PL2403645T3/pl

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Electrochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
PL10712600T 2009-03-06 2010-03-08 Mikroprzepływowe, elektrochemiczne urządzenia PL2403645T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15825109P 2009-03-06 2009-03-06

Publications (1)

Publication Number Publication Date
PL2403645T3 true PL2403645T3 (pl) 2017-05-31

Family

ID=42199621

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10712600T PL2403645T3 (pl) 2009-03-06 2010-03-08 Mikroprzepływowe, elektrochemiczne urządzenia

Country Status (7)

Country Link
US (1) US9192933B2 (pl)
EP (1) EP2403645B1 (pl)
AU (1) AU2010221102A1 (pl)
CA (1) CA2754577C (pl)
ES (1) ES2612507T3 (pl)
PL (1) PL2403645T3 (pl)
WO (1) WO2010102279A1 (pl)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101578520B (zh) 2006-10-18 2015-09-16 哈佛学院院长等 基于形成图案的多孔介质的横向流动和穿过生物测定装置、及其制备方法和使用方法
WO2009120963A2 (en) 2008-03-27 2009-10-01 President And Fellows Of Harvard College Paper-based cellular arrays
EP2257819A4 (en) * 2008-03-27 2017-10-11 President and Fellows of Harvard College Three-dimensional microfluidic devices
KR20100128340A (ko) 2008-03-27 2010-12-07 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 종이 기반 마이크로유체 시스템
CA2719322C (en) 2008-03-27 2018-11-27 President And Fellows Of Harvard College Cotton thread as a low-cost multi-assay diagnostic platform
PL2403645T3 (pl) 2009-03-06 2017-05-31 President And Fellows Of Harvard College Mikroprzepływowe, elektrochemiczne urządzenia
EP2531300A1 (en) 2010-02-03 2012-12-12 President and Fellows of Harvard College Devices and methods for multiplexed assays
WO2013036617A1 (en) * 2011-09-06 2013-03-14 President And Fellows Of Harvard College Microfluidic devices for multiplexed electrochemical detection
WO2013049348A2 (en) * 2011-09-27 2013-04-04 Diagnostics For All, Inc. Quantitative microfluidic devices
KR101659529B1 (ko) * 2011-11-10 2016-09-23 더 어드미니스트레이터 오브 더 튜레인 에듀케이셔널 펀드 종이기반 진단 테스트
FR2984183B1 (fr) * 2011-12-15 2016-07-01 Commissariat Energie Atomique Systeme microfluidique 3d a zones emboitees, son procede de preparation et ses utilisations
WO2013087888A1 (fr) * 2011-12-15 2013-06-20 Commissariat à l'énergie atomique et aux énergies alternatives Système microfluidique 3d à zones emboîtées et réservoir intégré, son procédé de préparation et ses utilisations
FR2997026A1 (fr) * 2012-10-23 2014-04-25 Commissariat Energie Atomique Systeme microfluidique 3d a zones emboitees et reservoir integre, son procede de preparation et ses utilisations
DE102012201843A1 (de) * 2012-02-08 2013-08-08 Siemens Aktiengesellschaft Anordnung und Verfahren zur elektrischen Detektion von flüssigen Proben mit Lateral Flow Assays
KR101360404B1 (ko) * 2012-05-02 2014-02-11 서강대학교산학협력단 잉크젯 프린팅을 이용한 모듈형 마이크로유체 종이 칩의 제작방법
CN102886280B (zh) * 2012-08-28 2014-06-11 博奥生物有限公司 一种微流控芯片及其应用
US9823249B2 (en) * 2012-12-12 2017-11-21 Brigham And Women's Hospital, Inc. System and method for detecting pathogens
US20160238583A1 (en) * 2012-12-20 2016-08-18 King Abdullah University Of Science And Technology Sensor for metal detection
US20160033438A1 (en) * 2013-03-15 2016-02-04 President And Fellows Of Harvard College Paper-Based Reference Electrode And Potentiometric Ion Sensing
EP2979086B8 (en) * 2013-03-28 2018-03-28 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Hydrogen sulfide detecting apparatus
DK3022340T3 (da) * 2013-07-18 2020-12-21 Univ Alberta Parallel organisk syntese på mønstret papir ved brug af et opløsningsmiddel afvisende materiale
US9500616B2 (en) * 2013-12-23 2016-11-22 Cilag Gmbh International Multi-orientation test strip
US9874539B2 (en) * 2014-05-23 2018-01-23 Regents Of The University Of Minnesota Ion-selective electrodes and reference electrodes with a solid contact having mesoporous carbon
WO2015184270A1 (en) * 2014-05-29 2015-12-03 Xiujun Li Methods and compositions for hybrid microfluidic devices integrated with nano-biosensors
GB201411094D0 (en) * 2014-06-22 2014-08-06 Technion Res And Dev Company Ltd Microfluidic electrokinetic paper based devices
US9586204B2 (en) 2014-06-23 2017-03-07 Xerox Corporation Paper sensor
US9933359B2 (en) 2014-06-23 2018-04-03 Xerox Corporation Vendor exclusivity security feature for paper-based diagnostic solution
US9686540B2 (en) 2014-06-23 2017-06-20 Xerox Corporation Robust colorimetric processing method for paper based sensors
US9638685B2 (en) * 2014-09-19 2017-05-02 Tokitae Llc Flow assay with at least one electrically-actuated fluid flow control valve and related methods
US10549273B2 (en) 2014-09-19 2020-02-04 Tokitae Llc Flow assay with at least one electrically-actuated fluid flow control valve and related methods
EP3292395A4 (en) 2015-04-08 2019-01-02 Board of Regents, The University of Texas System Methods and systems for the detection of analytes
DE102015005781A1 (de) * 2015-05-08 2016-11-10 Forschungszentrum Jülich GmbH Verfahren zur Herstellung einer Vorrichtung zum elektrochemischen Nachweis von Molekülen mittels Redox-Cycling, sowie Vorrichtung hierzu und deren Verwendung
WO2017014828A2 (en) * 2015-05-20 2017-01-26 President And Fellows Of Harvard College Device and method for electrochemical detection
WO2017091272A2 (en) * 2015-09-03 2017-06-01 President And Fellows Of Harvard College Electroanalytical devices with pins and thread
US10151699B2 (en) * 2015-10-12 2018-12-11 Hong Kong Baptist University Development of lead ion testing paper with naked-eye observable readout for ten min on-site detection
US10145825B2 (en) * 2015-10-12 2018-12-04 Hong Kong Baptist University Luminescent Iridium(III) complex and its uses thereof for the G-quadruplex-based switch-on rapid detection of lead ions
EP3156788B1 (en) * 2015-10-15 2018-12-26 ARKRAY, Inc. Biosensor
JP6783109B2 (ja) * 2015-10-15 2020-11-11 アークレイ株式会社 バイオセンサ
US11567028B2 (en) * 2015-11-29 2023-01-31 Ramot At Tel-Aviv University Ltd. Sensing electrode and method of fabricating the same
JP2018036091A (ja) * 2016-08-30 2018-03-08 アークレイ株式会社 バイオセンサ、及びその製造方法
EP3369483A1 (en) 2017-03-03 2018-09-05 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Improved microfluidic devices and methods to obtain them
CA3261113A1 (en) 2017-03-23 2025-10-27 Abbott Laboratories Methods for aiding in the diagnosis and determination of the extent of traumatic brain injury in a human subject using the early biomarker ubiquitin carboxy-terminal hydrolase l1
WO2018187535A1 (en) * 2017-04-07 2018-10-11 Tokitae Llc Flow assay with at least one electrically-actuated fluid flow control valve and related methods
CN110546513A (zh) 2017-04-15 2019-12-06 雅培实验室 使用早期生物标记物帮助超急性诊断和确定人类受试者中的创伤性脑损伤的方法
ES3053676T3 (en) 2017-04-28 2026-01-23 Abbott Lab Methods for aiding in the hyperacute diagnosis and determination of traumatic brain injury using early biomarkers on at least two samples from the same human subject
AU2018272054B2 (en) 2017-05-25 2024-10-31 Abbott Laboratories Methods for aiding in the determination of whether to perform imaging on a human subject who has sustained or may have sustained an injury to the head using early biomarkers
JP7269182B2 (ja) 2017-05-30 2023-05-08 アボット・ラボラトリーズ 心臓トロポニンｉ及び早期バイオマーカーを使用する、ヒト対象における軽度外傷性脳損傷を診断及び査定する一助となるための方法
JP2020523565A (ja) * 2017-06-07 2020-08-06 サン・ケミカル・コーポレーション 電気化学的バイオセンサー
CA3068041C (en) 2017-07-03 2024-06-25 Abbott Laboratories Improved methods for measuring ubiquitin carboxy-terminal hydrolase l1 levels in blood
US11022617B2 (en) 2017-12-09 2021-06-01 Abbott Laboratories Methods for aiding in the diagnosis and evaluation of a subject who has sustained an orthopedic injury and that has or may have sustained an injury to the head, such as mild traumatic brain injury (TBI), using glial fibrillary acidic protein (GFAP) and/or ubiquitin carboxy-terminal hydrolase L1 (UCH-L1)
EP3721234A1 (en) 2017-12-09 2020-10-14 Abbott Laboratories Methods for aiding in diagnosing and evaluating a traumatic brain injury in a human subject using a combination of gfap and uch-l1
AU2018395255B2 (en) 2017-12-29 2025-02-20 Abbott Laboratories Novel biomarkers and methods for diagnosing and evaluating traumatic brain injury
US12145147B2 (en) 2018-02-20 2024-11-19 Georgia Tech Research Corporation Microfluidic devices and method of making same
SG11202100721SA (en) 2018-07-23 2021-02-25 Univ Alberta Genetically-encoded bicyclic peptide libraries
CN109060923B (zh) * 2018-08-20 2023-06-09 浙江大学 折纸结构的体表汗液电化学传感器及监测方法
US10852268B2 (en) * 2018-08-29 2020-12-01 Medtronic, Inc. Electrochemical sensor including multiple work electrodes and common reference electrode
US11744492B2 (en) 2018-08-29 2023-09-05 Medtronic, Inc. Electrochemical sensor including multiple work electrodes and common reference electrode
IT201900002473A1 (it) * 2019-02-20 2020-08-20 Cardiovascular Lab S P A O Brevemente Cv Lab S P A Dispositivo e metodo elettroanalitico
US11366943B2 (en) * 2019-06-18 2022-06-21 International Business Machines Corporation Platform for design and prototyping of micro paper based devices
US11609207B2 (en) 2020-03-31 2023-03-21 Analog Devices International Unlimited Company Electrochemical sensor and method of forming thereof
AU2021379053A1 (en) * 2020-11-12 2023-02-23 F. Hoffmann-La Roche Ag Method for manufacturing at least one electrode of an analyte sensor
US12607597B2 (en) * 2021-09-22 2026-04-21 Rajul Sachin PATKAR Portable electrochemical nutrient testing device for soil health monitoring
JP7787679B2 (ja) * 2021-09-28 2025-12-17 キヤノン株式会社 マイクロ分析チップ、電解質濃度測定システムおよび電解質濃度測定方法
WO2023114978A1 (en) * 2021-12-17 2023-06-22 Abbott Laboratories Systems and methods for determining uch-l1, gfap, and other biomarkers in blood samples
US11926911B2 (en) 2022-02-07 2024-03-12 United States Of America As Represented By The Secretary Of The Air Force Microfluidic process for the general electrochemical synthesis of geminal dipseudohalide or halide-pseudohalide compounds
CA3243887A1 (en) * 2022-02-11 2023-08-17 Abbott Laboratories APPARATUS AND DEVICES FOR PROCESSING FLUID SAMPLES
JP7679334B2 (ja) * 2022-04-12 2025-05-19 キヤノン株式会社 マイクロ分析チップ
JP7730784B2 (ja) * 2022-04-23 2025-08-28 キヤノン株式会社 マイクロ分析チップ
JP7730785B2 (ja) * 2022-04-28 2025-08-28 キヤノン株式会社 マイクロ流路デバイス
EP4310489A1 (en) * 2022-07-21 2024-01-24 ETH Zurich Assay device for electrochemical sensing of a sample fluid
CN115656302B (zh) * 2022-11-10 2025-10-28 云南中烟工业有限责任公司 一种活体原位检测烟叶中关键成分的装置
US12140534B2 (en) * 2023-01-05 2024-11-12 Sequitur Health Corp. Devices, methods, and systems for deriving a permeate from a feed solution
US12030045B1 (en) 2023-01-05 2024-07-09 Sequitur Health Corp. Devices, methods, and systems for deriving ammonia gas from whole blood
KR102938065B1 (ko) 2023-02-13 2026-03-12 성신여자대학교 연구 산학협력단 미생물 기반 전기전도성 바이오 플라스틱
CN116651523A (zh) * 2023-05-26 2023-08-29 重庆大学 一种基于缝纫技术的电化学纸基分析设备的制作方法及应用
EP4635415A1 (en) * 2024-04-18 2025-10-22 Institutul National de Cercetare-Dezvoltare Pentru Fizica Materialelor-INCDFM Bucuresti Electrochemical device with integrated flexible fibrillary structure
WO2025226650A1 (en) * 2024-04-22 2025-10-30 Artemis Life Sciences Inc. Metal-coated screen-printed electrodes for trace element detection

Family Cites Families (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4668619A (en) 1980-10-30 1987-05-26 Miles Laboratories, Inc. Multilayer homogeneous specific binding assay device
US4757004A (en) 1984-03-16 1988-07-12 Syntex (U.S.A.) Inc. Chromatographic devices having modified edges
DE3445816C1 (de) 1984-12-15 1986-06-12 Behringwerke Ag, 3550 Marburg Flaechenfoermiges diagnostisches Mittel
US4618475A (en) 1985-08-30 1986-10-21 Miles Laboratories, Inc. Reagent test device containing hydrophobic barriers
US4668564A (en) 1985-12-26 1987-05-26 Spenco Medical Corporation Hydrogel materials for hot and cold therapy and method for forming same
US4743530A (en) 1986-11-21 1988-05-10 Eastman Kodak Company Negative working photoresists responsive to longer wavelengths and novel coated articles
US5209904A (en) 1987-12-23 1993-05-11 Abbott Laboratories Agglutination reaction device utilizing selectively impregnated porous material
US5869172A (en) 1988-03-14 1999-02-09 Nextec Applications, Inc. Internally-coated porous webs with controlled positioning of modifiers therein
US5120544A (en) 1989-06-19 1992-06-09 Henley International, Inc. Crosslinked hydrogel and method for making same
IT1241154B (it) 1990-05-18 1993-12-29 Slavo Metodo e composizione reagente per la determinazione dell'alanina amminotrasferasi e dell'antigene hbsag in uno stesso campione biologico
JPH0820412B2 (ja) 1990-07-20 1996-03-04 松下電器産業株式会社 使い捨てセンサを用いた定量分析方法、及び装置
US5834226A (en) 1991-01-31 1998-11-10 Xytronyx, Inc. One-step test for aspartate aminotransferase
US5409664A (en) 1993-09-28 1995-04-25 Chemtrak, Inc. Laminated assay device
US6180239B1 (en) 1993-10-04 2001-01-30 President And Fellows Of Harvard College Microcontact printing on surfaces and derivative articles
IL109079A (en) 1994-03-22 1998-02-22 Israel Fiber Inst State Of Isr Polyionic hydrogels
US5858392A (en) 1994-03-22 1999-01-12 Yissum Research Development Company Of The Hebrew University Of Jerusalem Supported polyionic hydrogels
DE4437274C2 (de) 1994-10-18 1998-11-05 Inst Chemo Biosensorik Analytselektiver Sensor
US5707818A (en) 1994-12-13 1998-01-13 Bsi Corporation Device and method for simultaneously performing multiple competitive immunoassays
JPH08233799A (ja) 1995-02-24 1996-09-13 Tefuko Kk 化学分析用膜およびその製造方法
US5906934A (en) 1995-03-14 1999-05-25 Morphogen Pharmaceuticals, Inc. Mesenchymal stem cells for cartilage repair
EP0784543B1 (en) 1995-08-04 2000-04-26 International Business Machines Corporation Lithographic surface or thin layer modification
US5897522A (en) 1995-12-20 1999-04-27 Power Paper Ltd. Flexible thin layer open electrochemical cell and applications of same
EP0873101B2 (en) 1996-01-11 2005-07-20 The Procter & Gamble Company Absorbent structure having zones surrounded by a continuous region of hydrogel-forming absorbent polymer
US6356234B1 (en) 1996-06-12 2002-03-12 R T Microwave Limited Electrical circuit
US6060534A (en) 1996-07-11 2000-05-09 Scimed Life Systems, Inc. Medical devices comprising ionically and non-ionically crosslinked polymer hydrogels having improved mechanical properties
DE19629655A1 (de) 1996-07-23 1998-01-29 Boehringer Mannheim Gmbh Diagnostischer Testträger und Verfahren zur Bestimmung eines Analyts mit dessen Hilfe
US6202471B1 (en) 1997-10-10 2001-03-20 Nanomaterials Research Corporation Low-cost multilaminate sensors
US6110354A (en) * 1996-11-01 2000-08-29 University Of Washington Microband electrode arrays
GB9623185D0 (en) 1996-11-09 1997-01-08 Epigem Limited Improved micro relief element and preparation thereof
GB9700759D0 (en) 1997-01-15 1997-03-05 Carbury Herne Limited Assay device
KR100241928B1 (ko) 1997-03-31 2000-03-02 박종근 다공성 박막 위에 전극이 일체로 형성된 정량장치 및 이를 이용한 정량방법
GB9715101D0 (en) 1997-07-18 1997-09-24 Environmental Sensors Ltd The production of microstructures for analysis of fluids
US6375871B1 (en) 1998-06-18 2002-04-23 3M Innovative Properties Company Methods of manufacturing microfluidic articles
DE19753847A1 (de) 1997-12-04 1999-06-10 Roche Diagnostics Gmbh Analytisches Testelement mit Kapillarkanal
US5997817A (en) * 1997-12-05 1999-12-07 Roche Diagnostics Corporation Electrochemical biosensor test strip
ATE400358T1 (de) 1997-12-24 2008-07-15 Cepheid Vorrichtung und verfahren zur lyse
US6180319B1 (en) 1998-03-11 2001-01-30 E. I. Du Pont De Nemours And Company Process for the continuous liquid processing of photosensitive compositions having reduced levels of residues
US6951682B1 (en) 1998-12-01 2005-10-04 Syntrix Biochip, Inc. Porous coatings bearing ligand arrays and use thereof
US6416642B1 (en) 1999-01-21 2002-07-09 Caliper Technologies Corp. Method and apparatus for continuous liquid flow in microscale channels using pressure injection, wicking, and electrokinetic injection
US6297020B1 (en) 1999-03-01 2001-10-02 Bayer Corporation Device for carrying out lateral-flow assays involving more than one analyte
US6319310B1 (en) 1999-03-30 2001-11-20 Xerox Corporation Phase change ink compositions
ES2222217T5 (es) 1999-07-07 2010-05-07 3M Innovative Properties Company Articulo de deteccion que tiene una pelicula para el control de fluidos con canales capilares.
US6713309B1 (en) 1999-07-30 2004-03-30 Large Scale Proteomics Corporation Microarrays and their manufacture
US20020006664A1 (en) 1999-09-17 2002-01-17 Sabatini David M. Arrayed transfection method and uses related thereto
JP2003527972A (ja) 1999-10-04 2003-09-24 ナノストリーム・インコーポレイテッド 挟まれたステンシルを含むモジュラー型マイクロ流体デバイス
US6931523B1 (en) 1999-12-09 2005-08-16 Gateway Inc. System and method for re-storing stored known-good computer configuration via a non-interactive user input device without re-booting the system
US6566575B1 (en) 2000-02-15 2003-05-20 3M Innovative Properties Company Patterned absorbent article for wound dressing
KR100348351B1 (ko) 2000-05-24 2002-08-09 주식회사 바이오디지트 전기화학 멤브레인 스트립 바이오센서
WO2002011888A2 (en) 2000-08-07 2002-02-14 Nanostream, Inc. Fluidic mixer in microfluidic system
US6391523B1 (en) 2000-09-15 2002-05-21 Microchem Corp. Fast drying thick film negative photoresist
US6783735B2 (en) 2000-09-15 2004-08-31 Agfa-Gevaert Web material having wells for combinatorial applications
US6503309B2 (en) 2001-01-10 2003-01-07 Milliken & Company Within ink systems
US6880576B2 (en) 2001-06-07 2005-04-19 Nanostream, Inc. Microfluidic devices for methods development
US7318912B2 (en) 2001-06-07 2008-01-15 Nanostream, Inc. Microfluidic systems and methods for combining discrete fluid volumes
US6919046B2 (en) 2001-06-07 2005-07-19 Nanostream, Inc. Microfluidic analytical devices and methods
US20030032203A1 (en) 2001-07-10 2003-02-13 Sabatini David M. Small molecule microarrays
WO2003015890A1 (en) 2001-08-20 2003-02-27 President And Fellows Of Harvard College Fluidic arrays and method of using
US20050230272A1 (en) 2001-10-03 2005-10-20 Lee Gil U Porous biosensing device
ATE509272T1 (de) 2001-11-09 2011-05-15 3Dbiosurfaces Technologies Llc Substrate mit hochliegendem oberflächenbereich für mikroarrays sowie verfahren zur herstellung davon
CN1311553C (zh) 2001-12-12 2007-04-18 松下电器产业株式会社 非易失性存储器及其制造方法
US6877892B2 (en) 2002-01-11 2005-04-12 Nanostream, Inc. Multi-stream microfluidic aperture mixers
US6921603B2 (en) 2002-04-24 2005-07-26 The Regents Of The University Of California Microfluidic fuel cell systems with embedded materials and structures and method thereof
GB0215858D0 (en) 2002-07-09 2002-08-14 Cambridge Display Tech Ltd Patterning method
WO2004006840A2 (en) 2002-07-12 2004-01-22 The Regents Of The University Of California Three dimensional cell patterned bioploymer scaffolds and method of making the same
EP1525056B1 (en) 2002-08-02 2007-04-04 GE Healthcare (SV) Corp. Integrated Microchip Design
US20040103808A1 (en) 2002-08-19 2004-06-03 Darren Lochun Electrical circuits and methods of manufacture and use
US6939450B2 (en) * 2002-10-08 2005-09-06 Abbott Laboratories Device having a flow channel
US20050266582A1 (en) 2002-12-16 2005-12-01 Modlin Douglas N Microfluidic system with integrated permeable membrane
US6816125B2 (en) 2003-03-01 2004-11-09 3M Innovative Properties Company Forming electromagnetic communication circuit components using densified metal powder
US20050145496A1 (en) 2003-04-03 2005-07-07 Federico Goodsaid Thermal reaction device and method for using the same
US7374949B2 (en) 2003-05-29 2008-05-20 Bayer Healthcare Llc Diagnostic test strip for collecting and detecting an analyte in a fluid sample
WO2005005974A1 (en) * 2003-06-17 2005-01-20 Huang, Alice, Y. Structure and manufacturing method of disposable electrochemical sensor strip
US8679853B2 (en) 2003-06-20 2014-03-25 Roche Diagnostics Operations, Inc. Biosensor with laser-sealed capillary space and method of making
US20060014003A1 (en) 2003-07-24 2006-01-19 Libera Matthew R Functional nano-scale gels
US20060088857A1 (en) 2003-12-01 2006-04-27 Said Attiya Method for isolation of independent, parallel chemical micro-reactions using a porous filter
AU2004312893B2 (en) 2003-12-31 2010-06-17 President And Fellows Of Harvard College Assay device and method
US7192693B2 (en) 2004-02-24 2007-03-20 University Of Washington Methods for photopatterning hydrogels
US20060257854A1 (en) 2004-02-27 2006-11-16 Mcdevitt John T Membrane assay system including preloaded particles
SE0400783D0 (sv) 2004-03-24 2004-03-24 Peter Aasberg Mönstringsmetod för biosensorapplikationer
DE102004019241A1 (de) 2004-04-16 2005-11-03 Cellmed Ag Injizierbare vernetzte und unvernetzte Alginate und ihre Verwendung in der Medizin und in der ästhetischen Chirurgie
JP5502275B2 (ja) 2004-05-02 2014-05-28 フルイディグム コーポレイション 熱反応デバイスおよびその熱反応デバイスの使用方法
SE0401219D0 (sv) 2004-05-10 2004-05-10 Biochromix Ab Metoder för detektera konformationsförändringar eller aggregering hos proteiner med hjälp av konjugerade polyelektrolyter
EP2650907B1 (en) 2004-06-04 2024-10-23 The Board Of Trustees Of The University Of Illinois Methods and devices for fabricating and assembling printable semiconductor elements
WO2006018044A1 (en) 2004-08-18 2006-02-23 Agilent Technologies, Inc. Microfluidic assembly with coupled microfluidic devices
US20060130054A1 (en) 2004-11-12 2006-06-15 Research In Motion Limited System and method for downloading or enabling download of a program from a program store location
US20060226575A1 (en) 2005-04-07 2006-10-12 Mariam Maghribi Micro-fabrication of bio-degradable polymeric implants
WO2007029250A1 (en) 2005-09-06 2007-03-15 Inverness Medical Switzerland Gmbh Method and apparatus for patterning a bibulous substrate
ES2551113T3 (es) 2006-01-04 2015-11-16 Glaxosmithkline Biologicals S.A. Proteína E1E2 del VHC adyuvantada con MF59 más vector de alfavirus que codifica E1E2 del VHC para provocar linfocitos T específicos del VHC
US20070224701A1 (en) 2006-02-16 2007-09-27 Becton, Dickinson And Company Combination vertical and lateral flow immunoassay device
DK2004907T3 (da) 2006-04-10 2009-10-19 Linea Tergi Ltd Fremgangsmåde til påföring af et metal på papir
AU2007310987B2 (en) 2006-10-18 2014-01-09 President And Fellows Of Harvard College Lateral flow and flow-through bioassay devices based on patterned porous media, methods of making same, and methods of using same
CN101578520B (zh) 2006-10-18 2015-09-16 哈佛学院院长等 基于形成图案的多孔介质的横向流动和穿过生物测定装置、及其制备方法和使用方法
WO2009120963A2 (en) 2008-03-27 2009-10-01 President And Fellows Of Harvard College Paper-based cellular arrays
EP2257819A4 (en) 2008-03-27 2017-10-11 President and Fellows of Harvard College Three-dimensional microfluidic devices
CA2719322C (en) 2008-03-27 2018-11-27 President And Fellows Of Harvard College Cotton thread as a low-cost multi-assay diagnostic platform
WO2009121038A2 (en) 2008-03-27 2009-10-01 President And Fellows Of Harvard College Shaped films of hydrogels fabricated using templates of patterned paper
KR20100128340A (ko) 2008-03-27 2010-12-07 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 종이 기반 마이크로유체 시스템
EP2143491A1 (en) 2008-07-10 2010-01-13 Carpegen GmbH Device for analysing a chemical or biological sample
WO2010022324A2 (en) 2008-08-22 2010-02-25 President And Fellows Of Harvard College Methods of patterning paper
AU2010221117A1 (en) 2009-03-06 2011-09-29 President And Fellows Of Harvard College Methods of micropatterning paper-based microfluidics
PL2403645T3 (pl) 2009-03-06 2017-05-31 President And Fellows Of Harvard College Mikroprzepływowe, elektrochemiczne urządzenia
EP2531300A1 (en) 2010-02-03 2012-12-12 President and Fellows of Harvard College Devices and methods for multiplexed assays

Also Published As

Publication number Publication date
CA2754577C (en) 2018-07-10
US20120181184A1 (en) 2012-07-19
CA2754577A1 (en) 2010-09-10
EP2403645B1 (en) 2016-10-26
AU2010221102A1 (en) 2011-09-29
ES2612507T3 (es) 2017-05-17
US9192933B2 (en) 2015-11-24
EP2403645A1 (en) 2012-01-11
WO2010102279A1 (en) 2010-09-10

Similar Documents

Publication Publication Date Title
PT3299800T (pt) Dispositivo microfluídico
GB0908613D0 (en) T Cell Reseptors
IL216624A0 (en) Fucosylation-deficient cells
EP2276043A4 (en) ELECTROCHEMICAL DEVICE
EP2366450A4 (en) MICRO CHANNEL DEVICE
GB0910759D0 (en) Microfluidic device
ZA201101475B (en) Electrochemical device
GB0909608D0 (en) Electrochemical assays
GB0911572D0 (en) Microfluidic devices
ZA201200109B (en) Lancet
EP2445617A4 (en) HIGH-TEMPERATURE STEAM LENSES MEMBRANE
GB0813669D0 (en) Electrolyte
TWI372137B (en) Dielectrophoresis-based microfluidic system
GB0920775D0 (en) Cells
AU326903S (en) Pipettes
AP2011005894A0 (en) 5-alkynyl-pyridines.
AU326904S (en) Pipettes
GB0917919D0 (en) Microfluidic mixer
GB201114689D0 (en) Pipettes
AP2011005789A0 (en) Sulfamoyl-phenyl-ureido benzamidine-derivatives asantimalarial agents.
GB0815472D0 (en) Microfluidic system
AP2011005899A0 (en) Plaswall.
GB0917917D0 (en) Microfluidic mixer
GB0922588D0 (en) Chemical processes
GB0817510D0 (en) Microfluidic structure