PL2430007T3 - Sposoby chemicznej syntezy związków diaminofenotiazyniowych z zastosowaniem nadsiarczanowych środków utleniających - Google Patents
Sposoby chemicznej syntezy związków diaminofenotiazyniowych z zastosowaniem nadsiarczanowych środków utleniającychInfo
- Publication number
- PL2430007T3 PL2430007T3 PL10718268T PL10718268T PL2430007T3 PL 2430007 T3 PL2430007 T3 PL 2430007T3 PL 10718268 T PL10718268 T PL 10718268T PL 10718268 T PL10718268 T PL 10718268T PL 2430007 T3 PL2430007 T3 PL 2430007T3
- Authority
- PL
- Poland
- Prior art keywords
- methods
- chemical synthesis
- diaminophenothiazinium compounds
- compounds involving
- oxidants
- Prior art date
Links
- KPYHKEZPEDJERZ-UHFFFAOYSA-N 10h-phenothiazine-1,2-diamine Chemical class C1=CC=C2NC3=C(N)C(N)=CC=C3SC2=C1 KPYHKEZPEDJERZ-UHFFFAOYSA-N 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000007800 oxidant agent Substances 0.000 title 1
- JRKICGRDRMAZLK-UHFFFAOYSA-L peroxydisulfate Chemical compound [O-]S(=O)(=O)OOS([O-])(=O)=O JRKICGRDRMAZLK-UHFFFAOYSA-L 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/18—[b, e]-condensed with two six-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C381/00—Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
- C07C381/02—Thiosulfates
Landscapes
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Virology (AREA)
- Hospice & Palliative Care (AREA)
- Tropical Medicine & Parasitology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17744609P | 2009-05-12 | 2009-05-12 | |
| PCT/GB2010/000927 WO2010130977A1 (en) | 2009-05-12 | 2010-05-11 | Methods of chemical synthesis of diaminophenothiazinium compounds involving the use of persulfate oxidants |
| EP10718268.5A EP2430007B1 (en) | 2009-05-12 | 2010-05-11 | Methods of chemical synthesis of diaminophenothiazinium compounds involving the use of persulfate oxidants |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2430007T3 true PL2430007T3 (pl) | 2014-07-31 |
Family
ID=42238536
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL10718268T PL2430007T3 (pl) | 2009-05-12 | 2010-05-11 | Sposoby chemicznej syntezy związków diaminofenotiazyniowych z zastosowaniem nadsiarczanowych środków utleniających |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8691979B2 (pl) |
| EP (1) | EP2430007B1 (pl) |
| DK (1) | DK2430007T3 (pl) |
| ES (1) | ES2457227T3 (pl) |
| PL (1) | PL2430007T3 (pl) |
| PT (1) | PT2430007E (pl) |
| SI (1) | SI2430007T1 (pl) |
| WO (1) | WO2010130977A1 (pl) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102634015B (zh) * | 2012-05-04 | 2013-06-19 | 中南大学 | 一种聚间苯二胺纳米粒子合成方法 |
| GB201317702D0 (en) | 2013-10-07 | 2013-11-20 | Wista Lab Ltd | Methods of chemical synthesis of diaminophenothiazinium compounds including methylthioninium chloride (MTC) |
| GB201621817D0 (en) | 2016-12-21 | 2017-02-01 | Wista Lab Ltd | Methods of chemical synthesis |
| EP3375777A1 (en) | 2017-03-15 | 2018-09-19 | MIKROCHEM spol. s.r.o. | Method for preparation of 3,7-bis-(dimethylamino)-phenothiazin-5-ium chloride or bromide |
| CN118359560B (zh) * | 2024-06-18 | 2024-09-24 | 珠海前列药业有限公司 | 一种亚甲蓝的制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1886C (de) | 1877-12-15 | 1877-12-15 | Basf Ag | Verfahren zur darstellung blauer farbstoffe aus dimethylanilin und anderen tertiaeren aromatischen monaminen |
| US5344928A (en) | 1991-04-26 | 1994-09-06 | Takeda Chemical Industries, Ltd. | Phenothiazine derivatives, their production and use |
| GB9506197D0 (en) | 1995-03-27 | 1995-05-17 | Hoffmann La Roche | Inhibition of tau-tau association. |
| GB0101049D0 (en) | 2001-01-15 | 2001-02-28 | Univ Aberdeen | Materials and methods relating to protein aggregation in neurodegenerative disease |
| GB0106953D0 (en) | 2001-03-20 | 2001-05-09 | Univ Aberdeen | Neufofibrillary labels |
| ES2409683T3 (es) | 2004-09-23 | 2013-06-27 | Wista Laboratories Ltd. | Procedimientos de síntesis química y purificación de compuestos de diaminofenotiazinio que incluyen cloruro de metiltioninio (CMT) |
-
2010
- 2010-05-11 ES ES10718268.5T patent/ES2457227T3/es active Active
- 2010-05-11 US US13/318,907 patent/US8691979B2/en not_active Expired - Fee Related
- 2010-05-11 PL PL10718268T patent/PL2430007T3/pl unknown
- 2010-05-11 DK DK10718268.5T patent/DK2430007T3/da active
- 2010-05-11 SI SI201030572T patent/SI2430007T1/sl unknown
- 2010-05-11 PT PT107182685T patent/PT2430007E/pt unknown
- 2010-05-11 EP EP10718268.5A patent/EP2430007B1/en active Active
- 2010-05-11 WO PCT/GB2010/000927 patent/WO2010130977A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010130977A1 (en) | 2010-11-18 |
| US20120058995A1 (en) | 2012-03-08 |
| EP2430007B1 (en) | 2014-02-12 |
| ES2457227T3 (es) | 2014-04-25 |
| PT2430007E (pt) | 2014-04-14 |
| SI2430007T1 (sl) | 2014-05-30 |
| US8691979B2 (en) | 2014-04-08 |
| DK2430007T3 (da) | 2014-05-12 |
| EP2430007A1 (en) | 2012-03-21 |
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