PL2438060T3 - Aktywny metabolit antagonisty receptora trombiny - Google Patents

Aktywny metabolit antagonisty receptora trombiny

Info

Publication number
PL2438060T3
PL2438060T3 PL10724627T PL10724627T PL2438060T3 PL 2438060 T3 PL2438060 T3 PL 2438060T3 PL 10724627 T PL10724627 T PL 10724627T PL 10724627 T PL10724627 T PL 10724627T PL 2438060 T3 PL2438060 T3 PL 2438060T3
Authority
PL
Poland
Prior art keywords
receptor antagonist
active metabolite
thrombin receptor
thrombin
metabolite
Prior art date
Application number
PL10724627T
Other languages
English (en)
Inventor
Natalia A Penner
Kimberly Nguyen Voronin
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of PL2438060T3 publication Critical patent/PL2438060T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL10724627T 2009-06-04 2010-06-02 Aktywny metabolit antagonisty receptora trombiny PL2438060T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18414709P 2009-06-04 2009-06-04
EP10724627.4A EP2438060B1 (en) 2009-06-04 2010-06-02 Active metabolite of a thrombin receptor antagonist
PCT/US2010/036984 WO2010141525A1 (en) 2009-06-04 2010-06-02 Active metabolite of a thrombin receptor antagonist

Publications (1)

Publication Number Publication Date
PL2438060T3 true PL2438060T3 (pl) 2014-03-31

Family

ID=43012674

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10724627T PL2438060T3 (pl) 2009-06-04 2010-06-02 Aktywny metabolit antagonisty receptora trombiny

Country Status (15)

Country Link
US (1) US8575351B2 (pl)
EP (1) EP2438060B1 (pl)
JP (1) JP5789256B2 (pl)
AR (1) AR076967A1 (pl)
AU (1) AU2010256711B2 (pl)
CA (1) CA2764159A1 (pl)
DK (1) DK2438060T3 (pl)
ES (1) ES2437100T3 (pl)
HR (1) HRP20131049T1 (pl)
MX (1) MX2011012861A (pl)
PL (1) PL2438060T3 (pl)
PT (1) PT2438060E (pl)
SI (1) SI2438060T1 (pl)
TW (1) TW201109319A (pl)
WO (1) WO2010141525A1 (pl)

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5150408A (en) 1991-02-27 1992-09-22 Motorola, Inc. Key distribution communication system
US7115632B1 (en) 1999-05-12 2006-10-03 G. D. Searle & Co. Sulfonyl aryl or heteroaryl hydroxamic acid compounds
US6063847A (en) 1997-11-25 2000-05-16 Schering Corporation Thrombin receptor antagonists
TW434220B (en) 1998-02-02 2001-05-16 Shiseido Co Ltd 1,2-di-substituted piperidine derivative, a hair growth agent, and an agent for external use to the skin
AU6690001A (en) 2000-06-15 2001-12-24 Schering Corp Thrombin receptor antagonists
US7235567B2 (en) 2000-06-15 2007-06-26 Schering Corporation Crystalline polymorph of a bisulfate salt of a thrombin receptor antagonist
US20040192753A1 (en) 2000-06-15 2004-09-30 Samuel Chackalamannil Methods of use of thrombin receptor antagonists
US7488742B2 (en) 2000-06-15 2009-02-10 Schering Corporation Thrombin receptor antagonists
KR100960170B1 (ko) 2001-10-18 2010-05-26 쉐링 코포레이션 트롬빈 수용체 길항제로서의 힘바신 동족체
JP4558331B2 (ja) 2002-04-16 2010-10-06 シェーリング コーポレイション 三環式トロンビンレセプターアンタゴニスト
TW200409637A (en) 2002-06-26 2004-06-16 Glaxo Group Ltd Compounds
BRPI0620641A2 (pt) 2005-12-22 2011-11-16 Schering Corp usos de compostos antagonistas de receptor de trombina na profilaxia de complicações de cirurgia cardiopulmonar
WO2008005352A2 (en) 2006-06-30 2008-01-10 Schering Corporation Solid dose formulations of a thrombin receptor antagonist
TWI367112B (en) 2006-06-30 2012-07-01 Schering Corp Immediate-release tablet formulations of a thrombin receptor antagonist
TWI343262B (en) 2006-09-26 2011-06-11 Schering Corp Rapidly disintegrating lyophilized oral formulations of a thrombin receptor antagonist
CN101553484A (zh) * 2006-10-04 2009-10-07 先灵公司 以喜巴辛的被改质三环单位为基础的凝血酶受体拮抗剂
AU2007305269A1 (en) * 2006-10-04 2008-04-10 Schering Corporation Bicyclic and tricyclic derivatives as thrombin receptor antagonists

Also Published As

Publication number Publication date
MX2011012861A (es) 2012-01-25
WO2010141525A1 (en) 2010-12-09
AU2010256711A1 (en) 2012-01-12
AR076967A1 (es) 2011-07-20
ES2437100T3 (es) 2014-01-08
CA2764159A1 (en) 2010-12-09
PT2438060E (pt) 2013-12-16
SI2438060T1 (sl) 2014-04-30
TW201109319A (en) 2011-03-16
US8575351B2 (en) 2013-11-05
JP5789256B2 (ja) 2015-10-07
HRP20131049T1 (hr) 2013-12-06
AU2010256711B2 (en) 2014-08-28
JP2012528868A (ja) 2012-11-15
DK2438060T3 (da) 2014-01-13
EP2438060A1 (en) 2012-04-11
US20120214845A1 (en) 2012-08-23
EP2438060B1 (en) 2013-10-02

Similar Documents

Publication Publication Date Title
FR22C1044I1 (fr) Antagonistes du recepteur cgrp
ZA201207292B (en) Cgrp receptor antagonist
PT2927224T (pt) Antagonistas de receptores
GB2485298B8 (en) A structural module for construction of buildings
DK2501703T3 (da) Spiropiperidinforbindelser som orl-1-receptorantagonister
AP3736A (en) A toilet
IL218649A0 (en) Oxytocin receptor agonists
IL220683A0 (en) Process for making a metabotropic glutamate receptor positive allosteric modulator-874
IL217526A0 (en) Carbocyclic glyt1 receptor antagonists
IL225395A0 (en) Antagonist for mutant androgen receptor
IL241743A0 (en) Non-competitive nicotinic receptor antagonists
SI2438060T1 (sl) Aktivni metabolit trombin receptorskega antagonista
TWM390210U (en) Improved structure of a tool holder
GB0922455D0 (en) Ep2 receptor antagonists
ZA200906466B (en) Reduction of adverse events after percutaneous intervention by use of a thrombin receptor antagonist
GB0900756D0 (en) EP4 Receptor antagonists
GB0900754D0 (en) EP4 Receptor antagonists
GB0901836D0 (en) EP4 receptor antagonists
GB0900755D0 (en) Ep4 receptor antagonists
TWM389282U (en) Wall embedded structure for a monitor
TWM385415U (en) Improved structure of a material-poking plate
GB2470048B (en) A bowl
AU328540S (en) A bowl
PL118331U1 (pl) Konstrukcja dopalacza regeneracyjnego