PL2455379T3 - Kryształy soli sodowych pirolochinolinochinonu - Google Patents

Kryształy soli sodowych pirolochinolinochinonu

Info

Publication number
PL2455379T3
PL2455379T3 PL10799695T PL10799695T PL2455379T3 PL 2455379 T3 PL2455379 T3 PL 2455379T3 PL 10799695 T PL10799695 T PL 10799695T PL 10799695 T PL10799695 T PL 10799695T PL 2455379 T3 PL2455379 T3 PL 2455379T3
Authority
PL
Poland
Prior art keywords
pyrroloquinolinequinone
crystals
sodium salts
salts
sodium
Prior art date
Application number
PL10799695T
Other languages
English (en)
Inventor
Junichi Edahiro
Hitoshi Sakamoto
Kazuto Ikemoto
Hajime Shimizu
Tatsuya Hasegawa
Masahiko Nakano
Original Assignee
Mitsubishi Gas Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Gas Chemical Co filed Critical Mitsubishi Gas Chemical Co
Publication of PL2455379T3 publication Critical patent/PL2455379T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15Vitamins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
PL10799695T 2009-07-16 2010-06-09 Kryształy soli sodowych pirolochinolinochinonu PL2455379T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2009168087 2009-07-16
EP10799695.1A EP2455379B1 (en) 2009-07-16 2010-06-09 Crystals of pyrroloquinolinequinone sodium salts
PCT/JP2010/059761 WO2011007633A1 (ja) 2009-07-16 2010-06-09 ピロロキノリンキノンのナトリウム塩結晶

Publications (1)

Publication Number Publication Date
PL2455379T3 true PL2455379T3 (pl) 2014-04-30

Family

ID=43449243

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10799695T PL2455379T3 (pl) 2009-07-16 2010-06-09 Kryształy soli sodowych pirolochinolinochinonu

Country Status (6)

Country Link
US (2) US9163014B2 (pl)
EP (1) EP2455379B1 (pl)
JP (1) JP5240362B2 (pl)
CN (2) CN104744462B (pl)
PL (1) PL2455379T3 (pl)
WO (1) WO2011007633A1 (pl)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2722331T3 (pl) * 2011-06-16 2018-02-28 Mitsubishi Gas Chemical Company, Inc. Kryształ soli disodowej pirolochinolinochinonu oraz sposób jego wytwarzania
JP6160621B2 (ja) * 2012-08-17 2017-07-12 三菱瓦斯化学株式会社 ピロロキノリンキノンテトラアルカリ塩及びその結晶、これらの製造方法、並びに、組成物
CN102942567B (zh) * 2012-11-09 2017-02-08 诸城市浩天药业有限公司 吡咯并喹啉醌的二钠盐结晶
JP6395101B2 (ja) * 2014-03-28 2018-09-26 三菱瓦斯化学株式会社 イミダゾピロロキノリン塩
MA39715A (fr) * 2014-04-16 2015-10-22 Anthem Biosciences Private Ltd Formes polymorphes de l'acide 4,5-dihydro-1h-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylique et de son sel de disodium, procédé de préparation desdites formes polymorphes et leur utilisation
EP3199154A4 (en) 2014-09-22 2018-02-28 National University Corporation Nagoya University Novel life-prolonging agent, life-prolonging method making use of same, novel dual oxidase activator, method for activating dual oxidase, manufacture of life-prolonging agent, and manufacture of dual oxidase activator
US10131661B2 (en) * 2015-01-19 2018-11-20 Mitsubishi Gas Chemical Company, Inc. High-solubility acetone-added pyrroloquinoline quinone salt
JP6697861B2 (ja) * 2015-09-18 2020-05-27 国立大学法人東海国立大学機構 新規なnadph酸化酵素活性化剤及びその製造方法、並びにnadph酸化酵素の活性化方法
US10364244B2 (en) 2015-09-25 2019-07-30 Zhejiang Hisun Pharmaceutical Co., Ltd. Crystal form of pyrroloquinoline quinone sodium salt and preparation method and use thereof
CN105218543B (zh) * 2015-11-02 2017-05-10 诸城市浩天药业有限公司 吡咯喹啉醌b晶型及其制备方法
EP3480197B1 (en) * 2016-06-29 2024-04-03 Mitsubishi Gas Chemical Company, Inc. Pyrroloquinone quinone monosodium, method for manufacturing same, and composition including same
JP6825330B2 (ja) 2016-11-25 2021-02-03 三菱瓦斯化学株式会社 オートファジー誘導剤
JP6974788B2 (ja) * 2016-12-26 2021-12-01 三菱瓦斯化学株式会社 イミダゾピロロキノリン塩及びその製造方法、並びに、医薬品、化粧品及び食品
CN108069962A (zh) * 2017-06-27 2018-05-25 山东金城生物药业有限公司 吡咯喹啉醌二钠盐晶体及其制备方法
CN109180674B (zh) * 2018-11-13 2019-06-28 福建康鸿生物科技有限公司 基于发酵液复合盐析的吡咯喹啉醌二钠盐分离纯化方法
EP4012403B1 (en) 2019-03-20 2024-12-18 Mitsubishi Gas Chemical Company, Inc. Method for analyzing pyrroloquinoline quinone
CN112125899B (zh) * 2019-06-24 2023-01-03 浙江可明生物医药有限公司 吡咯并喹啉醌二钠盐结晶、其制备方法及包含其的组合物
JP2021050199A (ja) * 2019-09-20 2021-04-01 三井化学アグロ株式会社 3−(4,4−ジフルオロ−3,4−ジヒドロ−3,3−ジメチルイソキノリン−1−イル)キノリンの新規結晶形
JP7449469B2 (ja) * 2020-04-01 2024-03-14 三菱瓦斯化学株式会社 結晶及びその製造方法、組成物、ソフトカプセル
CN112500407B (zh) * 2020-12-25 2022-03-11 西安蓝晓科技新材料股份有限公司 一种吡咯并喹啉醌二钠盐的纯化方法
CN115716825A (zh) * 2021-08-24 2023-02-28 浙江医药股份有限公司新昌制药厂 吡咯并喹啉醌二钠盐结晶、其制备方法及包含其的组合物
CN115724840A (zh) * 2021-08-26 2023-03-03 浙江医药股份有限公司新昌制药厂 涉及一种吡咯并喹啉醌三钠盐结晶、其制备方法及包含其的组合物
CN117327069B (zh) * 2023-09-27 2024-04-30 山东原力泰医药科技有限公司 吡咯并喹啉醌二钠盐晶型及其制备方法和应用
CN117426507B (zh) * 2023-11-22 2024-05-03 广州能量生物科技有限公司 一种保护线粒体和溶血栓的保健食品及其制备方法
CN117777147A (zh) * 2024-02-23 2024-03-29 内蒙古金达威药业有限公司 一种吡咯并喹啉醌二钠盐的晶型及其制备方法
CN119285634A (zh) * 2024-12-10 2025-01-10 诸城市浩天药业有限公司 吡咯喹啉醌二钠盐晶型及制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07113024B2 (ja) 1986-04-17 1995-12-06 三菱瓦斯化学株式会社 ピロロキノリンキノンの精製方法
JPS6475487A (en) * 1987-09-18 1989-03-22 Mitsubishi Gas Chemical Co Purification of pyrroloquinolinequinonoes
JP2751183B2 (ja) 1988-02-26 1998-05-18 三菱瓦斯化学株式会社 ピロロキノリンキノンの製造方法
JP2692167B2 (ja) 1988-09-01 1997-12-17 三菱瓦斯化学株式会社 ピロロキノリンキノン類の回収・精製方法
JPH02267284A (ja) * 1989-04-05 1990-11-01 Noritake Co Ltd 気相合成法による多結晶質ダイヤモンド系物体およびその製法
US5061711A (en) * 1989-10-09 1991-10-29 Mitsubishi Gas Chemical Company, Inc. Method of curing liver diseases by using pyrrolo quinoline quinone triesters and novel pyrrolo quinoline quinone triesters
JP3475969B2 (ja) 1993-08-27 2003-12-10 大日本インキ化学工業株式会社 共重合体樹脂エマルジョン、その製造方法及び防湿加工用組成物
EP2062892A4 (en) * 2006-09-08 2009-11-18 Kyowa Hakko Bio Co Ltd MEDIUM AGAINST HYPERTONIA
CN101851234A (zh) * 2009-04-03 2010-10-06 上海日馨生物科技有限公司 吡咯喹啉醌锂盐衍生物及其制备方法
CN101885725A (zh) * 2009-05-12 2010-11-17 江苏道琪生物科技有限公司 吡咯喹啉醌钠盐衍生物及其制备方法
PL2722331T3 (pl) 2011-06-16 2018-02-28 Mitsubishi Gas Chemical Company, Inc. Kryształ soli disodowej pirolochinolinochinonu oraz sposób jego wytwarzania

Also Published As

Publication number Publication date
EP2455379B1 (en) 2013-12-11
JP5240362B2 (ja) 2013-07-17
EP2455379A4 (en) 2012-10-24
US20160039816A1 (en) 2016-02-11
US9321770B2 (en) 2016-04-26
CN102471336A (zh) 2012-05-23
EP2455379A1 (en) 2012-05-23
CN104744462B (zh) 2016-09-21
US20120116087A1 (en) 2012-05-10
CN102471336B (zh) 2015-04-15
JPWO2011007633A1 (ja) 2012-12-27
US9163014B2 (en) 2015-10-20
WO2011007633A1 (ja) 2011-01-20
CN104744462A (zh) 2015-07-01

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