PL2455379T3 - Kryształy soli sodowych pirolochinolinochinonu - Google Patents
Kryształy soli sodowych pirolochinolinochinonuInfo
- Publication number
- PL2455379T3 PL2455379T3 PL10799695T PL10799695T PL2455379T3 PL 2455379 T3 PL2455379 T3 PL 2455379T3 PL 10799695 T PL10799695 T PL 10799695T PL 10799695 T PL10799695 T PL 10799695T PL 2455379 T3 PL2455379 T3 PL 2455379T3
- Authority
- PL
- Poland
- Prior art keywords
- pyrroloquinolinequinone
- crystals
- sodium salts
- salts
- sodium
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009168087 | 2009-07-16 | ||
| EP10799695.1A EP2455379B1 (en) | 2009-07-16 | 2010-06-09 | Crystals of pyrroloquinolinequinone sodium salts |
| PCT/JP2010/059761 WO2011007633A1 (ja) | 2009-07-16 | 2010-06-09 | ピロロキノリンキノンのナトリウム塩結晶 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2455379T3 true PL2455379T3 (pl) | 2014-04-30 |
Family
ID=43449243
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL10799695T PL2455379T3 (pl) | 2009-07-16 | 2010-06-09 | Kryształy soli sodowych pirolochinolinochinonu |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US9163014B2 (pl) |
| EP (1) | EP2455379B1 (pl) |
| JP (1) | JP5240362B2 (pl) |
| CN (2) | CN104744462B (pl) |
| PL (1) | PL2455379T3 (pl) |
| WO (1) | WO2011007633A1 (pl) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2722331T3 (pl) * | 2011-06-16 | 2018-02-28 | Mitsubishi Gas Chemical Company, Inc. | Kryształ soli disodowej pirolochinolinochinonu oraz sposób jego wytwarzania |
| JP6160621B2 (ja) * | 2012-08-17 | 2017-07-12 | 三菱瓦斯化学株式会社 | ピロロキノリンキノンテトラアルカリ塩及びその結晶、これらの製造方法、並びに、組成物 |
| CN102942567B (zh) * | 2012-11-09 | 2017-02-08 | 诸城市浩天药业有限公司 | 吡咯并喹啉醌的二钠盐结晶 |
| JP6395101B2 (ja) * | 2014-03-28 | 2018-09-26 | 三菱瓦斯化学株式会社 | イミダゾピロロキノリン塩 |
| MA39715A (fr) * | 2014-04-16 | 2015-10-22 | Anthem Biosciences Private Ltd | Formes polymorphes de l'acide 4,5-dihydro-1h-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylique et de son sel de disodium, procédé de préparation desdites formes polymorphes et leur utilisation |
| EP3199154A4 (en) | 2014-09-22 | 2018-02-28 | National University Corporation Nagoya University | Novel life-prolonging agent, life-prolonging method making use of same, novel dual oxidase activator, method for activating dual oxidase, manufacture of life-prolonging agent, and manufacture of dual oxidase activator |
| US10131661B2 (en) * | 2015-01-19 | 2018-11-20 | Mitsubishi Gas Chemical Company, Inc. | High-solubility acetone-added pyrroloquinoline quinone salt |
| JP6697861B2 (ja) * | 2015-09-18 | 2020-05-27 | 国立大学法人東海国立大学機構 | 新規なnadph酸化酵素活性化剤及びその製造方法、並びにnadph酸化酵素の活性化方法 |
| US10364244B2 (en) | 2015-09-25 | 2019-07-30 | Zhejiang Hisun Pharmaceutical Co., Ltd. | Crystal form of pyrroloquinoline quinone sodium salt and preparation method and use thereof |
| CN105218543B (zh) * | 2015-11-02 | 2017-05-10 | 诸城市浩天药业有限公司 | 吡咯喹啉醌b晶型及其制备方法 |
| EP3480197B1 (en) * | 2016-06-29 | 2024-04-03 | Mitsubishi Gas Chemical Company, Inc. | Pyrroloquinone quinone monosodium, method for manufacturing same, and composition including same |
| JP6825330B2 (ja) | 2016-11-25 | 2021-02-03 | 三菱瓦斯化学株式会社 | オートファジー誘導剤 |
| JP6974788B2 (ja) * | 2016-12-26 | 2021-12-01 | 三菱瓦斯化学株式会社 | イミダゾピロロキノリン塩及びその製造方法、並びに、医薬品、化粧品及び食品 |
| CN108069962A (zh) * | 2017-06-27 | 2018-05-25 | 山东金城生物药业有限公司 | 吡咯喹啉醌二钠盐晶体及其制备方法 |
| CN109180674B (zh) * | 2018-11-13 | 2019-06-28 | 福建康鸿生物科技有限公司 | 基于发酵液复合盐析的吡咯喹啉醌二钠盐分离纯化方法 |
| EP4012403B1 (en) | 2019-03-20 | 2024-12-18 | Mitsubishi Gas Chemical Company, Inc. | Method for analyzing pyrroloquinoline quinone |
| CN112125899B (zh) * | 2019-06-24 | 2023-01-03 | 浙江可明生物医药有限公司 | 吡咯并喹啉醌二钠盐结晶、其制备方法及包含其的组合物 |
| JP2021050199A (ja) * | 2019-09-20 | 2021-04-01 | 三井化学アグロ株式会社 | 3−(4,4−ジフルオロ−3,4−ジヒドロ−3,3−ジメチルイソキノリン−1−イル)キノリンの新規結晶形 |
| JP7449469B2 (ja) * | 2020-04-01 | 2024-03-14 | 三菱瓦斯化学株式会社 | 結晶及びその製造方法、組成物、ソフトカプセル |
| CN112500407B (zh) * | 2020-12-25 | 2022-03-11 | 西安蓝晓科技新材料股份有限公司 | 一种吡咯并喹啉醌二钠盐的纯化方法 |
| CN115716825A (zh) * | 2021-08-24 | 2023-02-28 | 浙江医药股份有限公司新昌制药厂 | 吡咯并喹啉醌二钠盐结晶、其制备方法及包含其的组合物 |
| CN115724840A (zh) * | 2021-08-26 | 2023-03-03 | 浙江医药股份有限公司新昌制药厂 | 涉及一种吡咯并喹啉醌三钠盐结晶、其制备方法及包含其的组合物 |
| CN117327069B (zh) * | 2023-09-27 | 2024-04-30 | 山东原力泰医药科技有限公司 | 吡咯并喹啉醌二钠盐晶型及其制备方法和应用 |
| CN117426507B (zh) * | 2023-11-22 | 2024-05-03 | 广州能量生物科技有限公司 | 一种保护线粒体和溶血栓的保健食品及其制备方法 |
| CN117777147A (zh) * | 2024-02-23 | 2024-03-29 | 内蒙古金达威药业有限公司 | 一种吡咯并喹啉醌二钠盐的晶型及其制备方法 |
| CN119285634A (zh) * | 2024-12-10 | 2025-01-10 | 诸城市浩天药业有限公司 | 吡咯喹啉醌二钠盐晶型及制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07113024B2 (ja) | 1986-04-17 | 1995-12-06 | 三菱瓦斯化学株式会社 | ピロロキノリンキノンの精製方法 |
| JPS6475487A (en) * | 1987-09-18 | 1989-03-22 | Mitsubishi Gas Chemical Co | Purification of pyrroloquinolinequinonoes |
| JP2751183B2 (ja) | 1988-02-26 | 1998-05-18 | 三菱瓦斯化学株式会社 | ピロロキノリンキノンの製造方法 |
| JP2692167B2 (ja) | 1988-09-01 | 1997-12-17 | 三菱瓦斯化学株式会社 | ピロロキノリンキノン類の回収・精製方法 |
| JPH02267284A (ja) * | 1989-04-05 | 1990-11-01 | Noritake Co Ltd | 気相合成法による多結晶質ダイヤモンド系物体およびその製法 |
| US5061711A (en) * | 1989-10-09 | 1991-10-29 | Mitsubishi Gas Chemical Company, Inc. | Method of curing liver diseases by using pyrrolo quinoline quinone triesters and novel pyrrolo quinoline quinone triesters |
| JP3475969B2 (ja) | 1993-08-27 | 2003-12-10 | 大日本インキ化学工業株式会社 | 共重合体樹脂エマルジョン、その製造方法及び防湿加工用組成物 |
| EP2062892A4 (en) * | 2006-09-08 | 2009-11-18 | Kyowa Hakko Bio Co Ltd | MEDIUM AGAINST HYPERTONIA |
| CN101851234A (zh) * | 2009-04-03 | 2010-10-06 | 上海日馨生物科技有限公司 | 吡咯喹啉醌锂盐衍生物及其制备方法 |
| CN101885725A (zh) * | 2009-05-12 | 2010-11-17 | 江苏道琪生物科技有限公司 | 吡咯喹啉醌钠盐衍生物及其制备方法 |
| PL2722331T3 (pl) | 2011-06-16 | 2018-02-28 | Mitsubishi Gas Chemical Company, Inc. | Kryształ soli disodowej pirolochinolinochinonu oraz sposób jego wytwarzania |
-
2010
- 2010-06-09 CN CN201510103290.7A patent/CN104744462B/zh active Active
- 2010-06-09 PL PL10799695T patent/PL2455379T3/pl unknown
- 2010-06-09 EP EP10799695.1A patent/EP2455379B1/en active Active
- 2010-06-09 JP JP2011522764A patent/JP5240362B2/ja active Active
- 2010-06-09 US US13/383,472 patent/US9163014B2/en active Active
- 2010-06-09 WO PCT/JP2010/059761 patent/WO2011007633A1/ja not_active Ceased
- 2010-06-09 CN CN201080031945.XA patent/CN102471336B/zh active Active
-
2015
- 2015-08-17 US US14/827,767 patent/US9321770B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2455379B1 (en) | 2013-12-11 |
| JP5240362B2 (ja) | 2013-07-17 |
| EP2455379A4 (en) | 2012-10-24 |
| US20160039816A1 (en) | 2016-02-11 |
| US9321770B2 (en) | 2016-04-26 |
| CN102471336A (zh) | 2012-05-23 |
| EP2455379A1 (en) | 2012-05-23 |
| CN104744462B (zh) | 2016-09-21 |
| US20120116087A1 (en) | 2012-05-10 |
| CN102471336B (zh) | 2015-04-15 |
| JPWO2011007633A1 (ja) | 2012-12-27 |
| US9163014B2 (en) | 2015-10-20 |
| WO2011007633A1 (ja) | 2011-01-20 |
| CN104744462A (zh) | 2015-07-01 |
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