PL2467489T3 - Wytwarzanie opartych na bakulowirusie środków biofarmaceutycznych wolnych od zanieczyszczających wirionów bakulowirusowych - Google Patents
Wytwarzanie opartych na bakulowirusie środków biofarmaceutycznych wolnych od zanieczyszczających wirionów bakulowirusowychInfo
- Publication number
- PL2467489T3 PL2467489T3 PL10743083T PL10743083T PL2467489T3 PL 2467489 T3 PL2467489 T3 PL 2467489T3 PL 10743083 T PL10743083 T PL 10743083T PL 10743083 T PL10743083 T PL 10743083T PL 2467489 T3 PL2467489 T3 PL 2467489T3
- Authority
- PL
- Poland
- Prior art keywords
- baculovirus
- based production
- biopharmaceuticals
- free
- baculoviral virions
- Prior art date
Links
- 229960000074 biopharmaceutical Drugs 0.000 title 1
- 241000701447 unidentified baculovirus Species 0.000 title 1
- 210000002845 virion Anatomy 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14141—Use of virus, viral particle or viral elements as a vector
- C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14151—Methods of production or purification of viral material
- C12N2710/14152—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/50—Vectors for producing vectors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09305761A EP2292781A1 (en) | 2009-08-17 | 2009-08-17 | Baculovirus-based production of biopharmaceuticals free of contaminating baculoviral virions |
| EP10743083.7A EP2467489B1 (en) | 2009-08-17 | 2010-08-05 | Baculovirus-based production of biopharmaceuticals free of contaminating baculoviral virions |
| PCT/EP2010/061456 WO2011020710A2 (en) | 2009-08-17 | 2010-08-05 | Baculovirus-based production of biopharmaceuticals free of contaminating baculoviral virions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2467489T3 true PL2467489T3 (pl) | 2015-10-30 |
Family
ID=41203903
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL10743083T PL2467489T3 (pl) | 2009-08-17 | 2010-08-05 | Wytwarzanie opartych na bakulowirusie środków biofarmaceutycznych wolnych od zanieczyszczających wirionów bakulowirusowych |
| PL16205440T PL3187589T3 (pl) | 2009-08-17 | 2010-08-05 | Oparte na bakulowirusie wytwarzanie środków biofarmaceutycznych wolnych od zanieczyszczających wirionów bakulowirusowych |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL16205440T PL3187589T3 (pl) | 2009-08-17 | 2010-08-05 | Oparte na bakulowirusie wytwarzanie środków biofarmaceutycznych wolnych od zanieczyszczających wirionów bakulowirusowych |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US8993317B2 (pl) |
| EP (4) | EP2292781A1 (pl) |
| CN (1) | CN102686732A (pl) |
| CA (2) | CA3050271A1 (pl) |
| DK (3) | DK2933336T3 (pl) |
| ES (3) | ES2787706T3 (pl) |
| HU (1) | HUE025056T2 (pl) |
| PL (2) | PL2467489T3 (pl) |
| PT (3) | PT2467489E (pl) |
| WO (1) | WO2011020710A2 (pl) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2292781A1 (en) * | 2009-08-17 | 2011-03-09 | Genethon | Baculovirus-based production of biopharmaceuticals free of contaminating baculoviral virions |
| US20140287460A1 (en) * | 2011-07-27 | 2014-09-25 | Gbiotech Sarl | Production of recombinant protein in insect cells using a baculovirus expression system |
| FR2978456B1 (fr) * | 2011-07-27 | 2015-02-20 | Genethon | Systeme baculoviral pour l'expression d'un vecteur de therapie genique |
| TWI698240B (zh) | 2012-05-15 | 2020-07-11 | 澳大利亞商艾佛蘭屈澳洲私營有限公司 | 使用腺相關病毒(aav)sflt-1治療老年性黃斑部退化(amd) |
| US9982239B2 (en) | 2012-06-12 | 2018-05-29 | Alternative Gene Expression S.L. | Baculoviral DNA elements for the expression of recombinant proteins in a host cell |
| EP3800191B1 (en) | 2014-03-17 | 2025-08-20 | Adverum Biotechnologies, Inc. | Compositions and methods for enhanced gene expression in cone cells |
| EP3151866B1 (en) | 2014-06-09 | 2023-03-08 | Voyager Therapeutics, Inc. | Chimeric capsids |
| RU2716991C2 (ru) | 2014-11-05 | 2020-03-17 | Вояджер Терапьютикс, Инк. | Полинуклеотиды aadc для лечения болезни паркинсона |
| KR20230145206A (ko) | 2014-11-14 | 2023-10-17 | 보이저 테라퓨틱스, 인크. | 조절성 폴리뉴클레오티드 |
| WO2016077687A1 (en) | 2014-11-14 | 2016-05-19 | Voyager Therapeutics, Inc. | Compositions and methods of treating amyotrophic lateral sclerosis (als) |
| US11697825B2 (en) | 2014-12-12 | 2023-07-11 | Voyager Therapeutics, Inc. | Compositions and methods for the production of scAAV |
| US11021519B2 (en) | 2015-03-02 | 2021-06-01 | Adverum Biotechnologies, Inc. | Compositions and methods for intravitreal delivery of polynucleotides to retinal cones |
| ES2865487T3 (es) | 2015-09-28 | 2021-10-15 | Univ North Carolina Chapel Hill | Métodos y composiciones para vectores virales que evaden los anticuerpos |
| GB2545763A (en) | 2015-12-23 | 2017-06-28 | Adverum Biotechnologies Inc | Mutant viral capsid libraries and related systems and methods |
| US11299751B2 (en) | 2016-04-29 | 2022-04-12 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
| EP3448874A4 (en) | 2016-04-29 | 2020-04-22 | Voyager Therapeutics, Inc. | COMPOSITIONS FOR TREATING A DISEASE |
| KR102427379B1 (ko) | 2016-05-18 | 2022-08-02 | 보이저 테라퓨틱스, 인크. | 헌팅톤 질환을 치료하기 위한 조성물 및 방법 |
| KR20240056729A (ko) | 2016-05-18 | 2024-04-30 | 보이저 테라퓨틱스, 인크. | 조절성 폴리뉴클레오티드 |
| JP7106461B2 (ja) * | 2016-06-07 | 2022-07-26 | セファイド | 熱安定性ポリメラーゼ阻害剤組成物及び方法 |
| WO2018044933A1 (en) | 2016-08-30 | 2018-03-08 | The Regents Of The University Of California | Methods for biomedical targeting and delivery and devices and systems for practicing the same |
| JP2020518259A (ja) | 2017-05-05 | 2020-06-25 | ボイジャー セラピューティクス インコーポレイテッドVoyager Therapeutics,Inc. | ハンチントン病治療組成物および方法 |
| JP2020518258A (ja) | 2017-05-05 | 2020-06-25 | ボイジャー セラピューティクス インコーポレイテッドVoyager Therapeutics,Inc. | 筋萎縮性側索硬化症(als)治療組成物および方法 |
| JOP20190269A1 (ar) | 2017-06-15 | 2019-11-20 | Voyager Therapeutics Inc | بولي نوكليوتيدات aadc لعلاج مرض باركنسون |
| CA3070087A1 (en) | 2017-07-17 | 2019-01-24 | Voyager Therapeutics, Inc. | Trajectory array guide system |
| EP3808849A1 (en) | 2017-08-03 | 2021-04-21 | Voyager Therapeutics, Inc. | Compositions and methods for delivery of aav |
| NZ762100A (en) | 2017-08-09 | 2025-12-19 | Bioverativ Therapeutics Inc | Nucleic acid molecules and uses thereof |
| AU2018338728B2 (en) | 2017-09-29 | 2025-01-02 | Centre National De La Recherche Scientifique (Cnrs) | Rescue of central and peripheral neurological phenotype of Friedreich's Ataxia by intravenous delivery |
| EP3697908A1 (en) | 2017-10-16 | 2020-08-26 | Voyager Therapeutics, Inc. | Treatment of amyotrophic lateral sclerosis (als) |
| TW202413649A (zh) | 2017-10-16 | 2024-04-01 | 美商航海家醫療公司 | 肌萎縮性脊髓側索硬化症(als)之治療 |
| MX2020010465A (es) | 2018-04-03 | 2021-01-08 | Vectores de virus para direccionamiento a tejidos oftalmicos. | |
| EP3774852A1 (en) | 2018-04-03 | 2021-02-17 | Stridebio, Inc. | Antibody-evading virus vectors |
| AU2019247748A1 (en) | 2018-04-03 | 2020-10-08 | Ginkgo Bioworks, Inc. | Antibody-evading virus vectors |
| KR20210019996A (ko) | 2018-05-15 | 2021-02-23 | 보이저 테라퓨틱스, 인크. | 파킨슨병의 치료를 위한 조성물 및 방법 |
| WO2019237376A1 (zh) * | 2018-06-16 | 2019-12-19 | 深圳市博奥康生物科技有限公司 | TXGP1基因定点整合至Raji细胞的方法及其应用 |
| WO2019237377A1 (zh) * | 2018-06-16 | 2019-12-19 | 深圳市博奥康生物科技有限公司 | 一种将SLEB2基因定点整合至Jurkat细胞的方法及其应用 |
| WO2019237374A1 (zh) * | 2018-06-16 | 2019-12-19 | 深圳市博奥康生物科技有限公司 | Mtabc3基因定点整合至a375细胞的方法及其应用 |
| CN108823176B (zh) * | 2018-07-20 | 2021-09-28 | 山西大学 | 一种重组杆状病毒及其构建方法和应用 |
| EP3833766A1 (en) | 2018-08-09 | 2021-06-16 | Bioverativ Therapeutics Inc. | Nucleic acid molecules and uses thereof for non-viral gene therapy |
| CN108998455B (zh) * | 2018-08-13 | 2021-03-16 | 西南大学 | 家蚕核型多角体病毒诱导型39k启动子及其重组载体和应用 |
| EP3856762A1 (en) | 2018-09-28 | 2021-08-04 | Voyager Therapeutics, Inc. | Frataxin expression constructs having engineered promoters and methods of use thereof |
| CN111434774B (zh) * | 2019-01-11 | 2023-06-23 | 陕西杆粒生物科技有限公司 | 一种解除高滴度抑制的杆状病毒表达载体 |
| AR118465A1 (es) | 2019-03-21 | 2021-10-06 | Stridebio Inc | Vectores de virus adenoasociados recombinantes |
| EP3947700A4 (en) | 2019-04-01 | 2023-01-04 | Tenaya Therapeutics, Inc. | Adeno-associated virus with engineered capsid |
| JP7805169B2 (ja) * | 2019-06-26 | 2026-01-23 | ビロベク,インコーポレイテッド | バキュロウイルス発現系 |
| JP2022551739A (ja) | 2019-10-17 | 2022-12-13 | ストライドバイオ,インコーポレイテッド | ニーマン・ピック病c型の治療のためのアデノ随伴ウイルスベクター |
| US12611436B2 (en) | 2019-10-17 | 2026-04-28 | Sarepta Therapeutics, Inc. | AAV transfer cassette |
| CN110940807A (zh) * | 2019-11-08 | 2020-03-31 | 江苏科技大学 | 研究家蚕基因抑制BmNPV DNA复制相关基因的表达的方法 |
| AU2021328475A1 (en) | 2020-08-19 | 2023-03-16 | Sarepta Therapeutics, Inc. | Adeno-associated virus vectors for treatment of Rett syndrome |
| WO2022046665A1 (en) * | 2020-08-23 | 2022-03-03 | Bioverativ Therapeutics Inc. | MODIFIED BACULOVIRUS SYSTEM FOR IMPROVED PRODUCTION OF CLOSED-ENDED DNA (ceDNA) |
| BR112023006305A2 (pt) | 2020-10-09 | 2023-05-09 | Tenaya Therapeutics Inc | Métodos e composições de terapia gênica com placofilina-2 |
| CN115491377B (zh) * | 2021-06-18 | 2025-09-16 | 北京三诺佳邑生物技术有限责任公司 | 一种诱导rna干扰和降低并清除细胞中病毒污染的核苷酸序列及应用 |
| CN115491436A (zh) * | 2021-06-18 | 2022-12-20 | 舒泰神(北京)生物制药股份有限公司 | 一种用于检测杆状病毒残留dna的引物、探针及方法 |
| MX2024002333A (es) * | 2021-08-23 | 2024-03-07 | Bioverativ Therapeutics Inc | Sistema de expresion de baculovirus. |
| CN114058598B (zh) * | 2021-11-04 | 2023-04-28 | 中国科学院精密测量科学与技术创新研究院 | 新的重组杆状病毒基因组插入位点及其应用 |
| WO2023201207A1 (en) | 2022-04-11 | 2023-10-19 | Tenaya Therapeutics, Inc. | Adeno-associated virus with engineered capsid |
| CN118956967A (zh) * | 2024-04-17 | 2024-11-15 | 和元生物技术(上海)股份有限公司 | 核酸分子、包含其的重组杆状病毒及其应用 |
| CN120137918B (zh) * | 2025-05-12 | 2025-09-02 | 中国林业科学研究院高原林业研究所 | 重组dsRNA-杆状病毒及其制备方法和应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4745051A (en) | 1983-05-27 | 1988-05-17 | The Texas A&M University System | Method for producing a recombinant baculovirus expression vector |
| EP0127839B1 (en) | 1983-05-27 | 1992-07-15 | THE TEXAS A&M UNIVERSITY SYSTEM | Method for producing a recombinant baculovirus expression vector |
| ZA848495B (en) | 1984-01-31 | 1985-09-25 | Idaho Res Found | Production of polypeptides in insect cells |
| CN1062601C (zh) * | 1992-03-24 | 2001-02-28 | 剑桥药物研究有限公司 | 病毒疫苗 |
| FR2756297B1 (fr) * | 1996-11-22 | 1999-01-08 | Centre Nat Rech Scient | Procede de production de virus recombinants |
| GB9919409D0 (en) * | 1999-08-18 | 1999-10-20 | Univ Oxford Brookes | Baculovirus expression system |
| JP2005532829A (ja) * | 2002-07-18 | 2005-11-04 | インヴィトロジェン コーポレーション | 組換え部位を含むウイルスベクター |
| US20060166363A1 (en) * | 2004-01-27 | 2006-07-27 | Sergei Zolotukhin | Modified baculovirus expression system for production of pseudotyped rAAV vector |
| EP2292781A1 (en) * | 2009-08-17 | 2011-03-09 | Genethon | Baculovirus-based production of biopharmaceuticals free of contaminating baculoviral virions |
-
2009
- 2009-08-17 EP EP09305761A patent/EP2292781A1/en not_active Withdrawn
-
2010
- 2010-08-05 CN CN2010800456298A patent/CN102686732A/zh active Pending
- 2010-08-05 EP EP15168775.3A patent/EP2933336B1/en not_active Not-in-force
- 2010-08-05 WO PCT/EP2010/061456 patent/WO2011020710A2/en not_active Ceased
- 2010-08-05 DK DK15168775.3T patent/DK2933336T3/en active
- 2010-08-05 ES ES16205440T patent/ES2787706T3/es active Active
- 2010-08-05 US US13/390,806 patent/US8993317B2/en not_active Expired - Fee Related
- 2010-08-05 PT PT107430837T patent/PT2467489E/pt unknown
- 2010-08-05 EP EP16205440.7A patent/EP3187589B1/en active Active
- 2010-08-05 PT PT151687753T patent/PT2933336T/pt unknown
- 2010-08-05 DK DK16205440.7T patent/DK3187589T3/da active
- 2010-08-05 ES ES10743083.7T patent/ES2542740T3/es active Active
- 2010-08-05 CA CA3050271A patent/CA3050271A1/en not_active Abandoned
- 2010-08-05 HU HUE10743083A patent/HUE025056T2/en unknown
- 2010-08-05 EP EP10743083.7A patent/EP2467489B1/en not_active Not-in-force
- 2010-08-05 DK DK10743083.7T patent/DK2467489T3/en active
- 2010-08-05 PT PT162054407T patent/PT3187589T/pt unknown
- 2010-08-05 PL PL10743083T patent/PL2467489T3/pl unknown
- 2010-08-05 CA CA2771250A patent/CA2771250C/en not_active Expired - Fee Related
- 2010-08-05 PL PL16205440T patent/PL3187589T3/pl unknown
- 2010-08-05 ES ES15168775.3T patent/ES2627744T3/es active Active
-
2015
- 2015-03-27 US US14/670,459 patent/US9862934B2/en not_active Expired - Fee Related
-
2017
- 2017-12-14 US US15/841,359 patent/US10428315B2/en not_active Expired - Fee Related
-
2019
- 2019-08-27 US US16/551,787 patent/US11236307B2/en not_active Expired - Fee Related
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