PL2473518T3 - Stabilizowane ligandy melanokortyny - Google Patents

Stabilizowane ligandy melanokortyny

Info

Publication number
PL2473518T3
PL2473518T3 PL10812701T PL10812701T PL2473518T3 PL 2473518 T3 PL2473518 T3 PL 2473518T3 PL 10812701 T PL10812701 T PL 10812701T PL 10812701 T PL10812701 T PL 10812701T PL 2473518 T3 PL2473518 T3 PL 2473518T3
Authority
PL
Poland
Prior art keywords
stabilized
melanocortin ligands
melanocortin
ligands
stabilized melanocortin
Prior art date
Application number
PL10812701T
Other languages
English (en)
Inventor
Kenneth A. Gruber
Original Assignee
Tensive Controls, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tensive Controls, Inc. filed Critical Tensive Controls, Inc.
Publication of PL2473518T3 publication Critical patent/PL2473518T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1024Tetrapeptides with the first amino acid being heterocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
PL10812701T 2009-08-31 2010-08-30 Stabilizowane ligandy melanokortyny PL2473518T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23862509P 2009-08-31 2009-08-31
EP10812701.0A EP2473518B1 (en) 2009-08-31 2010-08-30 Stabilized melanocortin ligands

Publications (1)

Publication Number Publication Date
PL2473518T3 true PL2473518T3 (pl) 2017-07-31

Family

ID=43628689

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10812701T PL2473518T3 (pl) 2009-08-31 2010-08-30 Stabilizowane ligandy melanokortyny

Country Status (9)

Country Link
US (1) US8541545B2 (pl)
EP (1) EP2473518B1 (pl)
CN (1) CN102574894A (pl)
CA (1) CA2809803A1 (pl)
DK (1) DK2473518T3 (pl)
ES (1) ES2624451T3 (pl)
HU (1) HUE031856T2 (pl)
PL (1) PL2473518T3 (pl)
WO (1) WO2011026015A2 (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013510881A (ja) * 2009-11-16 2013-03-28 イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ Ac−Arg−シクロ(Cys−D−Ala−His−D−Phe−Arg−Trp−Cys)−NH2の合成のための方法
US9402877B2 (en) * 2011-11-04 2016-08-02 Xion Pharmaceuticals Corporation Methods and compositions for oral administration of melanocortin receptor agonist compounds
HRP20211950T1 (hr) 2011-12-29 2022-03-18 Rhythm Pharmaceuticals, Inc. Postupak liječenja poremećaja u vezi sa melanokortin-4 receptorom u heterozigotnim nosiocima
US9534018B2 (en) 2012-03-13 2017-01-03 Tensive Controls Inc. Melanocortin analogs having enhanced activity and transport
US10351599B2 (en) 2014-09-19 2019-07-16 Tensive Controls, Inc. Anti-microbial peptides
EP3350200A4 (en) 2015-09-18 2019-03-27 Wake Forest University Health Services ANGIOTENSIN (1 7) ANALOGUE AND ASSOCIATED PROCEDURES
EP3356386B1 (en) 2015-09-30 2024-02-14 Rhythm Pharmaceuticals, Inc. Method of treating melanocortin-4 receptor pathway-associated disorders
US20210169969A1 (en) 2018-04-06 2021-06-10 Leonardus H.T. Van Der Ploeg Compositions for treating kidney disease
EP4605407A2 (en) * 2022-10-21 2025-08-27 Endevica Bio, Inc. Methods of stimulating appetite and/or increasing body weight using non-naturally occurring melanocortin receptor antagonist analogs
CN121548423A (zh) * 2023-02-17 2026-02-17 恩德维卡生物技术有限公司 使用非天然存在的黑皮质素类似物与抗gdf-15抗体预防和/或治疗与抗癌剂相关的副作用的方法
AU2024224162A1 (en) * 2023-02-21 2025-09-04 Endevica Bio, Inc. Methods of stimulating appetite and/or increasing body weight in subjects having a fibrotic disease using non-naturally occurring melanocortin analogs
WO2025123055A1 (en) * 2023-12-07 2025-06-12 Endevica Bio, Inc. Non-naturally occurring melanocortin analogs and associated methods for modulating weight gain
WO2025245294A1 (en) * 2024-05-22 2025-11-27 Endevica Bio, Inc. Non-naturally occurring melanocortin receptor agonists and uses thereof for modulating weight gain

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030064921A1 (en) * 1999-10-27 2003-04-03 The Regents Of The University Of California Methods and compounds for modulating melanocortin receptor ligand binding and activity
JP2004534851A (ja) * 2001-07-11 2004-11-18 パラチン テクノロジーズ インク. メラノコルチン受容体に特異的な線状および環状ペプチド
CA2539596A1 (en) * 2003-09-30 2005-04-07 Kilian Waldemar Conde-Frieboes Melanocortin receptor agonists
US20080280820A1 (en) * 2004-11-04 2008-11-13 Ulrich Sensfuss Novel Peptides for Use in the Treatment of Obesity
CN101676298A (zh) * 2005-07-08 2010-03-24 研究及应用科学协会股份有限公司 黑皮质素受体配体
HRP20130384T1 (en) * 2005-08-26 2013-06-30 Abbvie Inc. Therapeutically active alpha-msh analogues
TW200848424A (en) * 2007-06-15 2008-12-16 Sod Conseils Rech Applic Cyclic peptide melanocortin receptor ligands
PL2214693T3 (pl) * 2007-11-05 2016-03-31 Ipsen Pharma Sas Zastosowanie melanokortyn do leczenia insulinowrażliwości

Also Published As

Publication number Publication date
US8541545B2 (en) 2013-09-24
EP2473518A2 (en) 2012-07-11
CN102574894A (zh) 2012-07-11
ES2624451T3 (es) 2017-07-14
WO2011026015A3 (en) 2011-07-21
DK2473518T3 (en) 2017-03-27
CA2809803A1 (en) 2011-03-03
HUE031856T2 (en) 2017-08-28
EP2473518B1 (en) 2017-02-22
EP2473518A4 (en) 2013-06-12
WO2011026015A2 (en) 2011-03-03
US20120220525A1 (en) 2012-08-30

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