PL2485751T3 - GLYX-13 do stosowania w sposobie leczenia depresji opornej na leczenie - Google Patents

GLYX-13 do stosowania w sposobie leczenia depresji opornej na leczenie

Info

Publication number: PL2485751T3
Authority: PL; Poland
Prior art keywords: glyx; refractory depression; treating refractory; treating; depression
Prior art date: 2009-10-05

Application number

PL10822514T

Other languages

English (en)

Inventor

Joseph Moskal

Original Assignee

Univ Northwestern

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-10-05

Filing date

2010-10-05

Publication date

2014-10-31

2010-10-05 Application filed by Univ Northwestern filed Critical Univ Northwestern

2014-10-31 Publication of PL2485751T3 publication Critical patent/PL2485751T3/pl

Links

208000028552 Treatment-Resistant Depressive disease Diseases 0.000 title 1
GIBQQARAXHVEGD-BSOLPCOYSA-N rapastinel Chemical compound C[C@@H](O)[C@H](N)C(=O)N1CCC[C@H]1C(=O)N1[C@H](C(=O)N[C@@H]([C@@H](C)O)C(N)=O)CCC1 GIBQQARAXHVEGD-BSOLPCOYSA-N 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Gastroenterology & Hepatology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Epidemiology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Ceramic Products (AREA)
Glass Compositions (AREA)
Compositions Of Oxide Ceramics (AREA)

PL10822514T 2009-10-05 2010-10-05 GLYX-13 do stosowania w sposobie leczenia depresji opornej na leczenie PL2485751T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US24865009P	2009-10-05	2009-10-05
PCT/US2010/051415 WO2011044089A2 (en)	2009-10-05	2010-10-05	Methods of treating depression and other related diseases
EP10822514.5A EP2485751B1 (en)	2009-10-05	2010-10-05	GLYX-13 for use in a method of treating refractory depression

Publications (1)

Publication Number	Publication Date
PL2485751T3 true PL2485751T3 (pl)	2014-10-31

Family

ID=43857351

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PL10822514T PL2485751T3 (pl)	2009-10-05	2010-10-05	GLYX-13 do stosowania w sposobie leczenia depresji opornej na leczenie
PL15171991T PL2985032T3 (pl)	2009-10-05	2010-10-05	Glyx do stosowania do leczenia choroby alzheimera, choroby parkinsona lub choroby huntingtona

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
PL15171991T PL2985032T3 (pl)	2009-10-05	2010-10-05	Glyx do stosowania do leczenia choroby alzheimera, choroby parkinsona lub choroby huntingtona

Country Status (12)

Country	Link
EP (4)	EP2485751B1 (pl)
CY (1)	CY1118530T1 (pl)
DK (2)	DK2985032T3 (pl)
ES (2)	ES2721448T3 (pl)
HR (1)	HRP20140784T1 (pl)
HU (1)	HUE043807T2 (pl)
PL (2)	PL2485751T3 (pl)
PT (2)	PT2985032T (pl)
RS (1)	RS53513B1 (pl)
SI (1)	SI2485751T1 (pl)
SM (1)	SMT201400117B (pl)
WO (1)	WO2011044089A2 (pl)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
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KR101769999B1 (ko)	2008-09-18	2017-08-21	노오쓰웨스턴 유니버시티	Ｎｍｄａ 수용체 조절제 및 그의 용도
US8951968B2 (en)	2009-10-05	2015-02-10	Northwestern University	Methods of treating depression and other related diseases
KR101692275B1 (ko)	2010-02-11	2017-01-04	노오쓰웨스턴 유니버시티	２차 구조 안정화된 ｎｍｄａ 수용체 조절제 및 그의 용도
CA2789331C (en)	2010-02-11	2017-11-07	Northwestern University	Secondary structure stabilized nmda receptor modulators and uses thereof
US10583138B2 (en)	2012-07-12	2020-03-10	Glytech, Llc	Composition and method for treatment of depression and psychosis in humans
US9737531B2 (en)	2012-07-12	2017-08-22	Glytech, Llc	Composition and method for treatment of depression and psychosis in humans
SG194230A1 (en) *	2011-04-27	2013-12-30	Univ Northwestern	Methods of treating alzheimer's disease, huntington's disease, autism, or other disorders
WO2014059326A2 (en) *	2012-10-12	2014-04-17	Northwestern University	Methods of identifying compounds for treating depression and other related diseases
CA2899010A1 (en)	2013-01-29	2014-08-07	Naurex, Inc.	Spiro-lactam nmda receptor modulators and uses thereof
MX2015009773A (es)	2013-01-29	2016-08-05	Aptinyx Inc	Moduladores de receptores nmda de espiro-lactama y sus usos.
PE20151436A1 (es)	2013-01-29	2015-10-10	Naurex Inc	Moduladores de receptores nmda de espiro-lactama y sus usos
JP6531042B2 (ja)	2013-01-29	2019-06-12	アプティニックスインコーポレイテッド	スピロラクタム系ｎｍｄａ受容体モジュレーターおよびその使用
BR112015018087B1 (pt)	2013-01-29	2022-09-20	Aptinyx Inc	Compostos moduladores de receptor n-metil-d-aspartato (nmda) de espiro-lactama, composição farmacêutica e uso dos mesmos
EP3721799A1 (en) *	2013-12-13	2020-10-14	Northwestern University	Methods of treating brain disorders or identifying biomarkers related thereto
CN105327349A (zh) *	2014-06-18	2016-02-17	上海翰森生物医药科技有限公司	Nmda受体拮抗剂的医药用途及其药物组合物
WO2015200322A1 (en) *	2014-06-23	2015-12-30	Northwestern University	Methods of treating or ameliorating migraine
RU2017107033A (ru) *	2014-08-14	2018-09-14	Наурекс, Инк.	Способы лечения депрессии с применением модуляторов nmda
CN108601814A (zh) *	2015-10-16	2018-09-28	西北大学	用于治疗精神分裂症、双相障碍、认知损害和重度抑郁障碍的非典型抗精神病药和nmda调节剂的药物组合
US10591461B2 (en)	2016-04-28	2020-03-17	The Trustees Of The University Of Pennsylvania	Method of drug design and optimisation utilizing stereochemical mimicry
WO2017201285A1 (en)	2016-05-19	2017-11-23	Aptinyx Inc.	Spiro-lactam nmda receptor modulators and uses thereof
PE20190174A1 (es)	2016-05-19	2019-02-01	Aptinyx Inc	Moduladores del receptor espiro-lactama n-metil-d-aspartato y usos de los mismos
CN109661398B (zh)	2016-08-01	2022-07-05	阿普廷伊克斯股份有限公司	螺-内酰胺和二-螺-内酰胺nmda受体调节剂及其用途
SG11201900554YA (en)	2016-08-01	2019-02-27	Aptinyx Inc	Spiro-lactam nmda modulators and methods of using same
US10918637B2 (en)	2016-08-01	2021-02-16	Aptinyx Inc.	Spiro-lactam NMDA receptor modulators and uses thereof
AU2017306152A1 (en)	2016-08-01	2019-01-31	Aptinyx Inc.	Spiro-lactam NMDA receptor modulators and uses thereof
BR112019001921A2 (pt)	2016-08-01	2019-05-14	Aptinyx Inc.	moduladores do receptor nmda de espiro-lactama e seus usos
US11578072B2 (en)	2018-01-31	2023-02-14	Aptinyx Inc.	Spiro-lactam NMDA receptor modulators and uses thereof
US12012413B2 (en)	2019-11-11	2024-06-18	Tenacia Biotechnology (Hong Kong) Co., Limited	Methods of treating painful diabetic peripheral neuropathy

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4086196A (en)	1975-03-28	1978-04-25	Armour Pharmaceutical Company	Parathyroid hormone
US5763393A (en)	1996-05-17	1998-06-09	Neurotherapeutics L.P.	Neuroactive peptides
US20030065138A1 (en) *	2001-03-07	2003-04-03	University Of Utah Research Foundation	Linear gamma-carboxyglutamate rich conotoxins
WO2002072609A2 (en) *	2001-03-12	2002-09-19	Nyxis Neurotherapies, Inc	Neuroactive peptides for prevention and/or treatment of hypoxia and neuropathic pain
CA2534909A1 (en) *	2003-08-08	2005-02-17	The Burnham Institute	P16 mediated regulation of nmda receptors
US20050096311A1 (en) *	2003-10-30	2005-05-05	Cns Response	Compositions and methods for treatment of nervous system disorders

2010
- 2010-10-05 PL PL10822514T patent/PL2485751T3/pl unknown
- 2010-10-05 ES ES15171991T patent/ES2721448T3/es active Active
- 2010-10-05 EP EP10822514.5A patent/EP2485751B1/en active Active
- 2010-10-05 PT PT15171991T patent/PT2985032T/pt unknown
- 2010-10-05 ES ES10822514.5T patent/ES2493316T3/es active Active
- 2010-10-05 PL PL15171991T patent/PL2985032T3/pl unknown
- 2010-10-05 PT PT108225145T patent/PT2485751E/pt unknown
- 2010-10-05 RS RSP20140441 patent/RS53513B1/sr unknown
- 2010-10-05 SI SI201030702T patent/SI2485751T1/sl unknown
- 2010-10-05 EP EP14169137.8A patent/EP2813236A1/en not_active Withdrawn
- 2010-10-05 EP EP15171991.1A patent/EP2985032B1/en active Active
- 2010-10-05 HU HUE15171991A patent/HUE043807T2/hu unknown
- 2010-10-05 EP EP18248179.6A patent/EP3488856A1/en not_active Ceased
- 2010-10-05 WO PCT/US2010/051415 patent/WO2011044089A2/en not_active Ceased
- 2010-10-05 DK DK15171991.1T patent/DK2985032T3/en active
- 2010-10-05 DK DK10822514.5T patent/DK2485751T3/da active
- 2010-10-05 HR HRP20140784AT patent/HRP20140784T1/hr unknown
2014
- 2014-08-13 CY CY20141100649T patent/CY1118530T1/el unknown
- 2014-08-19 SM SM201400117T patent/SMT201400117B/xx unknown

Also Published As

Publication number	Publication date
EP2985032A1 (en)	2016-02-17
EP2485751A2 (en)	2012-08-15
EP2985032B1 (en)	2019-01-02
DK2485751T3 (da)	2014-08-18
PL2985032T3 (pl)	2019-07-31
WO2011044089A3 (en)	2012-02-16
PT2485751E (pt)	2014-09-01
CY1118530T1 (el)	2017-07-12
HRP20140784T1 (hr)	2014-10-10
EP2813236A1 (en)	2014-12-17
PT2985032T (pt)	2019-04-24
EP3488856A1 (en)	2019-05-29
WO2011044089A2 (en)	2011-04-14
EP2485751B1 (en)	2014-05-21
SI2485751T1 (sl)	2014-10-30
RS53513B1 (sr)	2015-02-27
EP2485751A4 (en)	2013-03-13
DK2985032T3 (en)	2019-04-15
ES2493316T3 (es)	2014-09-11
ES2721448T3 (es)	2019-07-31
HUE043807T2 (hu)	2019-09-30
SMT201400117B (it)	2014-11-10

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