PL2488202T3 - Przeciwciała terapeutyczne o aktywności miejscowej w przewodzie pokarmowym - Google Patents

Przeciwciała terapeutyczne o aktywności miejscowej w przewodzie pokarmowym

Info

Publication number
PL2488202T3
PL2488202T3 PL10824210T PL10824210T PL2488202T3 PL 2488202 T3 PL2488202 T3 PL 2488202T3 PL 10824210 T PL10824210 T PL 10824210T PL 10824210 T PL10824210 T PL 10824210T PL 2488202 T3 PL2488202 T3 PL 2488202T3
Authority
PL
Poland
Prior art keywords
digestive tract
antibody therapeutics
local activity
activity
local
Prior art date
Application number
PL10824210T
Other languages
English (en)
Inventor
Barbara S Fox
Douglas C Stafford
Original Assignee
Avaxia Biologics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avaxia Biologics Inc filed Critical Avaxia Biologics Inc
Publication of PL2488202T3 publication Critical patent/PL2488202T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241Tumor Necrosis Factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0031Rectum, anus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/542Mucosal route oral/gastrointestinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/12Immunoglobulins specific features characterized by their source of isolation or production isolated from milk
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
PL10824210T 2009-10-15 2010-10-15 Przeciwciała terapeutyczne o aktywności miejscowej w przewodzie pokarmowym PL2488202T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25199609P 2009-10-15 2009-10-15
PCT/US2010/052934 WO2011047328A1 (en) 2009-10-15 2010-10-15 Antibody therapeutics with local activity in the digestive tract
EP10824210.8A EP2488202B1 (en) 2009-10-15 2010-10-15 Antibody therapeutics with local activity in the digestive tract

Publications (1)

Publication Number Publication Date
PL2488202T3 true PL2488202T3 (pl) 2015-12-31

Family

ID=43876600

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10824210T PL2488202T3 (pl) 2009-10-15 2010-10-15 Przeciwciała terapeutyczne o aktywności miejscowej w przewodzie pokarmowym

Country Status (13)

Country Link
US (3) US20120258118A1 (pl)
EP (2) EP2992900A1 (pl)
JP (1) JP2013508300A (pl)
KR (1) KR20120098664A (pl)
CN (1) CN102596248A (pl)
AU (1) AU2010306563B2 (pl)
CA (1) CA2777823A1 (pl)
ES (1) ES2547872T3 (pl)
HU (1) HUE027077T2 (pl)
NZ (1) NZ599315A (pl)
PL (1) PL2488202T3 (pl)
PT (1) PT2488202E (pl)
WO (1) WO2011047328A1 (pl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2725035A1 (en) 2007-10-02 2014-04-30 Avaxia Biologics, Inc. Antibody therapy for use in the digestive tract
CA2816551A1 (en) * 2010-11-03 2012-05-10 Mcmaster University Method of treating mucosal inflammation
CN103917555A (zh) * 2011-08-01 2014-07-09 艾瓦夏生物制剂公司 人tnf特异性的牛科动物多克隆抗体
EP2791170A1 (en) 2011-12-16 2014-10-22 Synthon Biopharmaceuticals B.V. Compounds and methods for treating inflammatory diseases
ES2866935T3 (es) 2014-01-10 2021-10-20 Anaptysbio Inc Anticuerpos dirigidos contra interleucina-33 (IL-33)
FR3022462B1 (fr) * 2014-06-18 2018-04-27 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Composition orale d'anticorps anti-tnfalpha
JP6871948B2 (ja) 2016-04-27 2021-05-19 アッヴィ・インコーポレイテッド 抗il−13抗体を使用する、il−13活性が有害である疾患の治療方法
GB201701404D0 (en) 2017-01-27 2017-03-15 Micropharm Ltd Therapies for treating inflammatory disorders
EP3409688A1 (en) 2017-05-31 2018-12-05 Tillotts Pharma Ag Topical treatment of inflammatory bowel disease using anti-tnf-alpha antibodies and fragments thereof
EP3553155A1 (en) 2018-03-12 2019-10-16 INDIAN OIL CORPORATION Ltd. Nano perovskite materials as combustion improver for liquid and gaseous fuels
GB201812261D0 (en) * 2018-07-27 2018-09-12 Micropharm Ltd Therapies for treating oral mucositis
CN110672860B (zh) * 2019-11-04 2023-07-14 中国科学院近代物理研究所 五种细胞因子组合作为电离辐射损伤生物标志物
WO2022148549A1 (en) 2020-01-14 2022-07-14 Babylat Gmbh Apparatus and method for obtaining protein-enriched fractions from breast milk
FR3153092A1 (fr) * 2023-09-19 2025-03-21 Université De Bordeaux Anticorps et compositions pour le traitement d'une candidose

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4330338A (en) 1978-10-02 1982-05-18 Purdue Research Foundation Pharmaceutical coating composition, and preparation and dosages so coated
US4518433A (en) 1982-11-08 1985-05-21 Fmc Corporation Enteric coating for pharmaceutical dosage forms
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5126130A (en) 1986-11-24 1992-06-30 The Childrens Hospital Incorporated Monoclonal antibodies reactive with specific antigenic sites on human cytomegalovirus glycoprotein a
AU667533B2 (en) * 1992-03-26 1996-03-28 Microcarb, Inc. Monospecific polyclonal antibodies to shiga-like toxins
US20030186882A1 (en) * 2001-07-31 2003-10-02 Podolsky Daniel K. Methods and compositions for treating and preventing distal bowel lesions
US6395273B1 (en) * 1998-06-10 2002-05-28 Promega Corporation Prevention and treatment of inflammatory bowel disease
SI1583830T1 (sl) 2003-01-07 2006-12-31 Symphogen As Postopek za pripravo rekombinantnih poliklonskih proteinov
US20040185047A1 (en) * 2003-03-21 2004-09-23 Jill Giles-Komar Anti- TNF antibodies, compositions, methods and uses
CA2684392A1 (en) * 2007-04-16 2008-10-23 Friesland Brands B.V. Milk derived antigen specific antibodies, methods of preparation and uses thereof
EP1982999A1 (en) * 2007-04-16 2008-10-22 Friesland Brands B.V. Milk derived antigen specific antibodies, methods of preparation and uses thereof
EP2215474A4 (en) * 2007-07-16 2012-07-18 Avaxia Biologics Inc ANTIBODY THERAPY FOR MODULATING THE FUNCTION OF DARM RECEPTORS
EP2725035A1 (en) 2007-10-02 2014-04-30 Avaxia Biologics, Inc. Antibody therapy for use in the digestive tract

Also Published As

Publication number Publication date
EP2488202A1 (en) 2012-08-22
HK1173973A1 (en) 2013-05-31
US20120258118A1 (en) 2012-10-11
EP2488202A4 (en) 2013-01-23
AU2010306563A1 (en) 2012-05-03
WO2011047328A1 (en) 2011-04-21
AU2010306563B2 (en) 2013-11-28
JP2013508300A (ja) 2013-03-07
US20170008957A1 (en) 2017-01-12
NZ599315A (en) 2014-05-30
KR20120098664A (ko) 2012-09-05
EP2488202B1 (en) 2015-07-08
CA2777823A1 (en) 2011-04-21
PT2488202E (pt) 2015-10-19
US20140010822A1 (en) 2014-01-09
HUE027077T2 (en) 2016-08-29
EP2992900A1 (en) 2016-03-09
ES2547872T3 (es) 2015-10-09
CN102596248A (zh) 2012-07-18

Similar Documents

Publication Publication Date Title
EP2488202A4 (en) ANTIBODY THERAPY AGENTS WITH LOCAL ACTIVITY IN THE DIGESTIVE STRUCTURE
EP2494062A4 (en) ANTI-GLP-1R ANTIBODIES AND THEIR USES
ZA201107486B (en) Anti-tnf-x antibodies and their uses
ZA201204480B (en) Conjugate with target-finding ligand and use thereof
ZA201207249B (en) Human anti-il-6 antibodies with extended in vivo half-life
EP2478110A4 (en) CLASS I ANTI-CEA ANTIBODIES AND USES THEREOF
ZA201201218B (en) 3-polylysine conjugates and the use thereof
SG10201503904XA (en) Anti-human trop-2 antibody having antitumor activity in vivo
ZA201106983B (en) Soluble "heavy-chain only" antibodies
IL215291A0 (en) NOVEL ANTI-a5BETA1 ANTIBODIES AND USES THEREOF
IL216304A0 (en) Blocking anti- dkk-1 antibodies and their uses
IL220536A0 (en) Anti - bv8 antibodies and uses thereof
IL219435A0 (en) Intraluminal device with improved flexibility and durability
EP2394001A4 (en) QUASI-ISOTROPIC SANDWICH STRUCTURES
IL217209A0 (en) Novel antibodies and their uses in therapeutic and diagnostic methods
GB0903151D0 (en) Antibody uses and methods
IL214527A0 (en) Anti-mst1r antibodies and uses thereof
EP2510000A4 (en) Anti-inflammatory antibodies and applications thereof
GB0906115D0 (en) Antibody and uses thereof
EP2481234A4 (en) X-MIMO SYSTEMS WITH MULTIPLE TRANSMITTERS AND MULTIPLE RECEIVERS
GB0911407D0 (en) Antibody and diagnostic use
GB0902425D0 (en) Butterfly technology
GB201001170D0 (en) Novel peptides and their use in therepy and diagnosis
GB0701831D0 (en) Serving and dining trolley
GB0909640D0 (en) Improvements in pushchairs and like mechanisms