PL250077B1 - Application of the peptide derivative of the phosphonic analogue of arginine Cbz-Val-Ser-ArgP(OPh)2 as an antibacterial agent - Google Patents

Application of the peptide derivative of the phosphonic analogue of arginine Cbz-Val-Ser-ArgP(OPh)2 as an antibacterial agent

Info

Publication number
PL250077B1
PL250077B1 PL445145A PL44514523A PL250077B1 PL 250077 B1 PL250077 B1 PL 250077B1 PL 445145 A PL445145 A PL 445145A PL 44514523 A PL44514523 A PL 44514523A PL 250077 B1 PL250077 B1 PL 250077B1
Authority
PL
Poland
Prior art keywords
argp
oph
cbz
phosphonic
val
Prior art date
Application number
PL445145A
Other languages
Polish (pl)
Other versions
PL445145A1 (en
Inventor
Ewa Burchacka
Original Assignee
Politechnika Wrocławska
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Politechnika Wrocławska filed Critical Politechnika Wrocławska
Priority to PL445145A priority Critical patent/PL250077B1/en
Publication of PL445145A1 publication Critical patent/PL445145A1/en
Publication of PL250077B1 publication Critical patent/PL250077B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Przedmiotem zgłoszenia jest zastosowanie peptydowej pochodnej fosfonowego analogu argininy Cbz-Val-Ser-ArgP(OPh)2 o wzorze 1 jako środka o aktywności przeciwbakteryjnej do eliminowania bakterii chorobotwórczych wybranych z grupy: Finegoldia magna, Escherichia coli, Staphylococcus aureus, Serratia marcescens.The subject of the application is the use of a peptide derivative of the phosphonic analogue of arginine Cbz-Val-Ser-ArgP(OPh)2 of formula 1 as an agent with antibacterial activity for eliminating pathogenic bacteria selected from the group: Finegoldia magna, Escherichia coli, Staphylococcus aureus, Serratia marcescens.

PL445145A 2023-06-06 2023-06-06 Application of the peptide derivative of the phosphonic analogue of arginine Cbz-Val-Ser-ArgP(OPh)2 as an antibacterial agent PL250077B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL445145A PL250077B1 (en) 2023-06-06 2023-06-06 Application of the peptide derivative of the phosphonic analogue of arginine Cbz-Val-Ser-ArgP(OPh)2 as an antibacterial agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL445145A PL250077B1 (en) 2023-06-06 2023-06-06 Application of the peptide derivative of the phosphonic analogue of arginine Cbz-Val-Ser-ArgP(OPh)2 as an antibacterial agent

Publications (2)

Publication Number Publication Date
PL445145A1 PL445145A1 (en) 2024-12-09
PL250077B1 true PL250077B1 (en) 2026-08-10

Family

ID=93799859

Family Applications (1)

Application Number Title Priority Date Filing Date
PL445145A PL250077B1 (en) 2023-06-06 2023-06-06 Application of the peptide derivative of the phosphonic analogue of arginine Cbz-Val-Ser-ArgP(OPh)2 as an antibacterial agent

Country Status (1)

Country Link
PL (1) PL250077B1 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL212735B1 (en) * 2006-02-28 2012-11-30 Politechnika Wroclawska Method for the manufacture of the phosphonic analogues of pseudopeptides and their application as inhibitors of the proteolytic enzymes as well as compounds with bactericidal activity
PL218889B1 (en) * 2013-04-29 2015-02-27 Politechnika Wroclawska Process for the preparation of peptide derivatives of diphenyl esters of 1-aminoalkane-phosphorus acids

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL212735B1 (en) * 2006-02-28 2012-11-30 Politechnika Wroclawska Method for the manufacture of the phosphonic analogues of pseudopeptides and their application as inhibitors of the proteolytic enzymes as well as compounds with bactericidal activity
PL218889B1 (en) * 2013-04-29 2015-02-27 Politechnika Wroclawska Process for the preparation of peptide derivatives of diphenyl esters of 1-aminoalkane-phosphorus acids

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BURCHACKA E. ET AL., (2014),: "Biochimie, Volume 103, 08.2014., pp 137-143.", „SUBSTRATE PROFILING OF FINEGOLDIA MAGNA SUFA PROTEASE, INHIBITOR SCREENING AND APPLICATION TO PREVENT HUMAN FIBRINOGEN DEGRADATION AND BACTERIA GROWTH IN VITRO", *
SKOREŃSKI M, MILEWSKA A, PYRĆ K, SIEŃCZYK M, OLEKSYSZYN J.: "J Enzyme Inhib Med Chem. 2019 Dec;34(1):8-14.", PHOSPHONATE INHIBITORS OF WEST NILE VIRUS NS2B/NS3 PROTEASE. *

Also Published As

Publication number Publication date
PL445145A1 (en) 2024-12-09