PL2513115T3 - Antybiotyki tricykliczne - Google Patents

Antybiotyki tricykliczne

Info

Publication number
PL2513115T3
PL2513115T3 PL10793255T PL10793255T PL2513115T3 PL 2513115 T3 PL2513115 T3 PL 2513115T3 PL 10793255 T PL10793255 T PL 10793255T PL 10793255 T PL10793255 T PL 10793255T PL 2513115 T3 PL2513115 T3 PL 2513115T3
Authority
PL
Poland
Prior art keywords
tricyclic
antibiotics
tricyclic antibiotics
Prior art date
Application number
PL10793255T
Other languages
English (en)
Inventor
Bérangère Gaucher
Franck Hubert Danel
Xiaohu Tang
Tong Xie
Lin Xu
Original Assignee
Basilea Pharmaceutica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basilea Pharmaceutica Ag filed Critical Basilea Pharmaceutica Ag
Publication of PL2513115T3 publication Critical patent/PL2513115T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C07D491/147—Ortho-condensed systems the condensed system containing one ring with oxygen as ring hetero atom and two rings with nitrogen as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
PL10793255T 2009-12-18 2010-12-17 Antybiotyki tricykliczne PL2513115T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09179956 2009-12-18
EP10793255.0A EP2513115B1 (en) 2009-12-18 2010-12-17 Tricyclic antibiotics
PCT/EP2010/070043 WO2011073378A1 (en) 2009-12-18 2010-12-17 Tricyclic antibiotics

Publications (1)

Publication Number Publication Date
PL2513115T3 true PL2513115T3 (pl) 2014-04-30

Family

ID=41716611

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10793255T PL2513115T3 (pl) 2009-12-18 2010-12-17 Antybiotyki tricykliczne

Country Status (19)

Country Link
US (2) US8927541B2 (pl)
EP (1) EP2513115B1 (pl)
JP (1) JP5697685B2 (pl)
KR (1) KR101891834B1 (pl)
CN (1) CN102666548B (pl)
AU (1) AU2010332767B2 (pl)
BR (1) BR112012014519A8 (pl)
CA (1) CA2780006A1 (pl)
CY (1) CY1114802T1 (pl)
DK (1) DK2513115T3 (pl)
ES (1) ES2441348T3 (pl)
HR (1) HRP20140005T1 (pl)
MX (1) MX2012006094A (pl)
PL (1) PL2513115T3 (pl)
PT (1) PT2513115E (pl)
SI (1) SI2513115T1 (pl)
TW (1) TWI487709B (pl)
WO (1) WO2011073378A1 (pl)
ZA (1) ZA201203540B (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2838036A1 (en) 2011-06-17 2012-12-20 Basilea Pharmaceutica Ag Tricyclic antibiotics
TWI598099B (zh) * 2012-04-30 2017-09-11 健生科學愛爾蘭無限公司 新化合物及其新用途
GB201406486D0 (en) 2014-04-10 2014-05-28 Redx Pharma Ltd Antibacterial compounds
WO2016105468A1 (en) * 2014-12-23 2016-06-30 Proteostasis Therapeutics, Inc. Derivatives of 3-heteroarylisoxazol-5-carboxylic amide useful for the treatment of inter alia cystic fibrosis
CN110177796B (zh) * 2017-01-06 2022-04-08 阿斯克里斯有限公司 喹啉酮衍生物及其用于预防或治疗变应性疾病的药物组合物
EP4493551A1 (en) 2022-03-14 2025-01-22 Slap Pharmaceuticals LLC Multicyclic compounds

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5430148A (en) 1992-03-31 1995-07-04 Agouron Pharmaceuticals, Inc. Antiproliferative quinazolines
EP1330460B1 (en) 2000-10-26 2007-03-21 Smithkline Beecham Plc Benzoxazinone derivatives, their preparation and use
TW200406413A (en) 2002-06-26 2004-05-01 Glaxo Group Ltd Compounds
TW200427688A (en) 2002-12-18 2004-12-16 Glaxo Group Ltd Antibacterial agents
US7037909B2 (en) 2003-07-02 2006-05-02 Sugen, Inc. Tetracyclic compounds as c-Met inhibitors
JP2007513082A (ja) 2003-11-10 2007-05-24 シエーリング アクチエンゲゼルシャフト Ｃｃｒ−５アンタゴニストとして有用なベンジルエーテルアミン化合物
GB0403038D0 (en) 2004-02-11 2004-03-17 Novartis Ag Organic compounds
JP2008505920A (ja) * 2004-07-08 2008-02-28 グラクソ　グループ　リミテッド 抗菌剤
DE102004041163A1 (de) 2004-08-25 2006-03-02 Morphochem Aktiengesellschaft für kombinatorische Chemie Neue Verbindungen mit antibakterieller Aktivität
WO2006038734A1 (en) 2004-10-08 2006-04-13 Astellas Pharma Inc. Pyridazinone derivatives cytokines inhibitors
TW200615273A (en) * 2004-11-10 2006-05-16 Nicholas Piramal India Ltd Fused tricyclic compounds as inhibitors of tumor necrosis factor-alpha
CN101184487B (zh) 2005-03-31 2010-11-03 詹森药业有限公司 作为抗菌剂的二环吡唑化合物
WO2007052843A1 (ja) 2005-11-04 2007-05-10 Takeda Pharmaceutical Company Limited 複素環アミド化合物およびその用途
ATE550329T1 (de) 2006-02-13 2012-04-15 Hoffmann La Roche Heterobicyclische sulfonamidderivate zur behandlung von diabetes
GB0613208D0 (en) 2006-07-03 2006-08-09 Glaxo Group Ltd Compounds
GB0707708D0 (en) * 2007-04-20 2007-05-30 Glaxo Group Ltd Compounds
WO2009012647A1 (fr) 2007-07-20 2009-01-29 Shanghai Hengrui Pharmaceutical Co., Ltd. Procédés de préparation de dérivés de quinazoline et leurs utilisations pharmaceutiques
WO2009125809A1 (ja) 2008-04-11 2009-10-15 第一三共株式会社 ピペリジン誘導体
WO2009125808A1 (ja) * 2008-04-11 2009-10-15 第一三共株式会社 アミノシクロヘキシル誘導体
CN102007128A (zh) 2008-04-15 2011-04-06 埃科特莱茵药品有限公司 三环抗生素
DE102008028996B4 (de) 2008-06-20 2011-06-09 Technische Universität Braunschweig Verfahren zur Nachbehandlung einer Schweißverbindung
CA2731365A1 (en) 2008-08-04 2010-02-11 Actelion Pharmaceuticals Ltd Tricyclic alkylaminomethyloxazolidinone derivatives

Also Published As

Publication number Publication date
ZA201203540B (en) 2013-01-30
DK2513115T3 (da) 2014-01-13
MX2012006094A (es) 2012-06-19
US9120822B2 (en) 2015-09-01
BR112012014519A2 (pt) 2016-08-16
EP2513115A1 (en) 2012-10-24
JP2013514331A (ja) 2013-04-25
WO2011073378A1 (en) 2011-06-23
CA2780006A1 (en) 2011-06-23
PT2513115E (pt) 2013-12-19
SI2513115T1 (sl) 2014-02-28
HRP20140005T1 (hr) 2014-01-31
KR101891834B1 (ko) 2018-09-28
US20120245345A1 (en) 2012-09-27
HK1174026A1 (en) 2013-05-31
AU2010332767B2 (en) 2014-04-24
AU2010332767A1 (en) 2012-05-24
CN102666548A (zh) 2012-09-12
US8927541B2 (en) 2015-01-06
CN102666548B (zh) 2015-07-15
TW201132645A (en) 2011-10-01
KR20120101711A (ko) 2012-09-14
US20150072975A1 (en) 2015-03-12
EP2513115B1 (en) 2013-10-09
BR112012014519A8 (pt) 2017-12-26
JP5697685B2 (ja) 2015-04-08
ES2441348T3 (es) 2014-02-04
CY1114802T1 (el) 2016-12-14
TWI487709B (zh) 2015-06-11

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