PL2528923T3 - Sposób wytwarzania darunawiru i pochodnych darunawiru - Google Patents

Sposób wytwarzania darunawiru i pochodnych darunawiru

Info

Publication number
PL2528923T3
PL2528923T3 PL11736707T PL11736707T PL2528923T3 PL 2528923 T3 PL2528923 T3 PL 2528923T3 PL 11736707 T PL11736707 T PL 11736707T PL 11736707 T PL11736707 T PL 11736707T PL 2528923 T3 PL2528923 T3 PL 2528923T3
Authority
PL
Poland
Prior art keywords
darunavir
intermediates
preparation
darunavir intermediates
Prior art date
Application number
PL11736707T
Other languages
English (en)
Inventor
Michael Mizhiritskii
Ehud Marom
Original Assignee
Mapi Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mapi Pharma Ltd filed Critical Mapi Pharma Ltd
Publication of PL2528923T3 publication Critical patent/PL2528923T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PL11736707T 2010-01-28 2011-01-24 Sposób wytwarzania darunawiru i pochodnych darunawiru PL2528923T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US29894110P 2010-01-28 2010-01-28
IL2010000533 2010-07-01
PCT/IL2011/000079 WO2011092687A1 (en) 2010-01-28 2011-01-24 Process for the preparation of darunavir and darunavir intermediates
EP11736707.8A EP2528923B1 (en) 2010-01-28 2011-01-24 Process for the preparation of darunavir and darunavir intermediates

Publications (1)

Publication Number Publication Date
PL2528923T3 true PL2528923T3 (pl) 2015-01-30

Family

ID=44318738

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11736707T PL2528923T3 (pl) 2010-01-28 2011-01-24 Sposób wytwarzania darunawiru i pochodnych darunawiru

Country Status (12)

Country Link
US (1) US8829208B2 (pl)
EP (1) EP2528923B1 (pl)
JP (1) JP2013518096A (pl)
CN (1) CN102725295A (pl)
AU (1) AU2011210349A1 (pl)
BR (1) BR112012018862A2 (pl)
CA (1) CA2784398A1 (pl)
ES (1) ES2516916T3 (pl)
IL (1) IL220477A (pl)
MX (1) MX2012008627A (pl)
PL (1) PL2528923T3 (pl)
WO (1) WO2011092687A1 (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8921415B2 (en) 2009-01-29 2014-12-30 Mapi Pharma Ltd. Polymorphs of darunavir
BR112012009956A2 (pt) 2009-10-30 2015-09-29 Lupin Ltd um novo processo para a preparação de darunavir e etanolato darunavir de tamanho de partícula.
PL2528923T3 (pl) 2010-01-28 2015-01-30 Mapi Pharma Ltd Sposób wytwarzania darunawiru i pochodnych darunawiru
EP3795572B1 (en) 2012-07-24 2023-11-15 Laurus Labs Limited Darunavir propionate solvate
CN105085323B (zh) * 2014-05-14 2017-02-15 重庆圣华曦药业股份有限公司 达芦那韦中间体的合成新工艺
CN105315178B (zh) * 2014-07-09 2018-07-06 浙江九洲药业股份有限公司 达芦那韦相关物质及其制备方法
JP6435907B2 (ja) * 2015-02-16 2018-12-12 住友化学株式会社 ヘキサヒドロフロフラノール誘導体の製造方法
CN113307783B (zh) * 2016-05-07 2023-04-07 成都博腾药业有限公司 一种制备地瑞那韦中间体的方法
CN108226329A (zh) * 2017-12-25 2018-06-29 浙江天宇药业股份有限公司 L-脯氨酰胺的液相色谱分析方法

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Also Published As

Publication number Publication date
ES2516916T3 (es) 2014-10-31
BR112012018862A2 (pt) 2015-10-13
AU2011210349A1 (en) 2012-07-05
EP2528923B1 (en) 2014-07-30
US20120296101A1 (en) 2012-11-22
JP2013518096A (ja) 2013-05-20
IL220477A (en) 2015-06-30
MX2012008627A (es) 2012-09-21
EP2528923A1 (en) 2012-12-05
CN102725295A (zh) 2012-10-10
US8829208B2 (en) 2014-09-09
EP2528923A4 (en) 2013-06-19
WO2011092687A1 (en) 2011-08-04
CA2784398A1 (en) 2011-08-04

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