PL2529739T3 - Środek terapeutyczny lub profilaktyczny na choroby dróg żółciowych - Google Patents

Środek terapeutyczny lub profilaktyczny na choroby dróg żółciowych

Info

Publication number
PL2529739T3
PL2529739T3 PL11737151.8T PL11737151T PL2529739T3 PL 2529739 T3 PL2529739 T3 PL 2529739T3 PL 11737151 T PL11737151 T PL 11737151T PL 2529739 T3 PL2529739 T3 PL 2529739T3
Authority
PL
Poland
Prior art keywords
therapeutic
prophylactic agent
biliary diseases
biliary
diseases
Prior art date
Application number
PL11737151.8T
Other languages
English (en)
Inventor
Ryosuke Kobayashi
Kaoru Nakao
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of PL2529739T3 publication Critical patent/PL2529739T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL11737151.8T 2010-01-29 2011-01-28 Środek terapeutyczny lub profilaktyczny na choroby dróg żółciowych PL2529739T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2010018730 2010-01-29

Publications (1)

Publication Number Publication Date
PL2529739T3 true PL2529739T3 (pl) 2016-12-30

Family

ID=44319422

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11737151.8T PL2529739T3 (pl) 2010-01-29 2011-01-28 Środek terapeutyczny lub profilaktyczny na choroby dróg żółciowych

Country Status (16)

Country Link
US (1) US10131672B2 (pl)
EP (1) EP2529739B1 (pl)
JP (1) JP5867081B2 (pl)
KR (1) KR101732042B1 (pl)
CN (1) CN102711759B (pl)
AU (1) AU2011211223B2 (pl)
BR (1) BR112012018765B1 (pl)
CA (1) CA2787323C (pl)
ES (1) ES2582628T3 (pl)
MX (1) MX362830B (pl)
MY (1) MY173491A (pl)
PH (1) PH12012501552A1 (pl)
PL (1) PL2529739T3 (pl)
RU (1) RU2554857C2 (pl)
TW (1) TWI477505B (pl)
WO (1) WO2011093441A1 (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112013009505B1 (pt) * 2010-10-19 2022-06-21 Memorial Sloan-Kettering Cancer Center Composto, composição farmacêutica, métodos para ensaio quanto a um receptor, e, usos de um composto
CN103327977B (zh) 2011-01-31 2016-05-04 东丽株式会社 恶液质的治疗或预防剂
EP4212532A3 (en) 2015-04-30 2023-09-27 Memorial Sloan Kettering Cancer Center Mitragynine analogs and uses thereof
CN106110220B (zh) * 2016-08-22 2020-01-07 陕西盘龙药业集团股份有限公司 一种治疗胆道疾病的中成药的制备工艺
CA3091752A1 (en) 2018-03-08 2019-09-12 Victoria Link Ltd Treatment of demyelinating diseases
CN118512451A (zh) 2018-07-23 2024-08-20 特雷维治疗股份有限公司 慢性咳嗽、呼吸急促和呼吸困难的治疗
WO2020205735A1 (en) * 2019-03-29 2020-10-08 Humanwell Pharmaceutical US Novel morphinans useful for treating medical disorders
IL294601A (en) 2020-01-10 2022-09-01 Trevi Therapeutics Inc Methods of administration of nalbuphine
MX2023014819A (es) 2021-06-14 2024-03-21 Scorpion Therapeutics Inc Derivados de la urea que pueden ser utilizados para tratar el cancer.

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946848A (en) * 1985-10-29 1990-08-07 Baker Cumins Dermatologicals, Inc. Method of treating pruritus with nalmefene and clonidine
WO1993000080A1 (en) * 1991-06-24 1993-01-07 Zeneca Ltd. Use of 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione in the treatment of tyrosinaemia and pharmaceutical compositions
JP2525552B2 (ja) 1992-01-23 1996-08-21 東レ株式会社 モルヒナン誘導体および医薬用途
CN1111900A (zh) 1993-06-30 1995-11-15 东丽株式会社 止咳药
KR100341950B1 (ko) 1993-07-19 2002-11-29 도레이 가부시끼가이샤 뇌세포보호제
DE69507697T2 (de) * 1994-05-31 1999-06-10 Mallinckrodt Chemical, Inc., Chesterfield, Mo. Verfahren zur herstellung von nalbuphin das wenig des 6-beta-epimers enthält
CN1535687A (zh) 1996-11-25 2004-10-13 ������������ʽ���� 止痒药物
WO1999005146A1 (en) 1997-07-25 1999-02-04 Toray Industries, Inc. Hyponatremia remedies
CA2270955C (en) 1997-09-02 2007-08-07 Toray Industries Inc. Pharmaceutical composition containing morphinan derivative for treating drug dependence
JP2000053572A (ja) * 1998-08-11 2000-02-22 Toray Ind Inc ORL1(opioid orphan)受容体拮抗薬
ES2308990T3 (es) 1999-08-24 2008-12-16 Toray Industries, Inc. Remedios para el dolor neuropatico y modelos animales de dolor neuropatico.
JP2001163784A (ja) 1999-12-06 2001-06-19 Toray Ind Inc 角膜または結膜用止痒剤
JP4453254B2 (ja) 2001-03-30 2010-04-21 東レ株式会社 レストレス・レッグズ症候群治療薬
JP4239592B2 (ja) 2001-05-08 2009-03-18 東レ株式会社 敗血症治療剤
US20030054030A1 (en) * 2001-09-13 2003-03-20 Gary Gordon Method and compositions for the treatment of pruritus
DE10161963A1 (de) * 2001-12-17 2003-07-03 Johannes Schuetz 6-Aminomorphinanderivate, Herstellungsverfahren dafür und deren Verwendung
US6852713B2 (en) 2003-04-16 2005-02-08 Adolor Corporation Lactam derivatives and methods of their use
US6992193B2 (en) 2003-06-10 2006-01-31 Adolor Corporation Sulfonylamino phenylacetamide derivatives and methods of their use
US7034051B2 (en) 2003-08-28 2006-04-25 Adolor Corporation Fused bicyclic carboxamide derivatives and methods of their use
US7160902B2 (en) 2003-11-14 2007-01-09 Adolor Corporation Amide derivatives and methods of their use
CN101137658B (zh) 2005-03-10 2011-06-08 东丽株式会社 用于与多发性硬化症伴随的搔痒的止痒剂
MX2009011449A (es) * 2007-04-24 2010-01-25 Toray Industries Agente terapeutico o profilactico para disquinesia.
MX2009014181A (es) 2007-06-22 2010-03-04 Toray Industries Remedio o preventivo para sindrome de disfuncion de integracion.
BRPI0817804A8 (pt) * 2007-10-05 2017-04-18 Toray Industries Agente terapêutico para melhorar as propriedades da pele compreendendo um derivado de morfinano ou qualquer um de seus sais de adição de ácido farmacologicamente permissíveis como um ingrediente ativo
JP2011512360A (ja) * 2008-02-14 2011-04-21 アルカーメス,インコーポレイテッド 選択的オピオイド化合物
WO2009132313A2 (en) * 2008-04-25 2009-10-29 Progenics Pharmaceuticals, Inc. Morphinan derivatives of organic and inorganic acids

Also Published As

Publication number Publication date
CN102711759A (zh) 2012-10-03
CA2787323A1 (en) 2011-08-04
JPWO2011093441A1 (ja) 2013-06-06
KR20120139713A (ko) 2012-12-27
RU2554857C2 (ru) 2015-06-27
EP2529739A1 (en) 2012-12-05
BR112012018765B1 (pt) 2019-09-03
US20130203797A1 (en) 2013-08-08
BR112012018765A2 (pt) 2016-05-03
KR101732042B1 (ko) 2017-05-02
TWI477505B (zh) 2015-03-21
EP2529739A4 (en) 2015-03-11
MX362830B (es) 2019-02-14
MX2012008509A (es) 2012-08-31
CN102711759B (zh) 2015-05-13
PH12012501552A1 (en) 2017-04-26
CA2787323C (en) 2017-08-29
EP2529739B1 (en) 2016-07-13
WO2011093441A1 (ja) 2011-08-04
TW201200521A (en) 2012-01-01
AU2011211223A1 (en) 2012-09-20
ES2582628T3 (es) 2016-09-14
MY173491A (en) 2020-01-29
RU2012136826A (ru) 2014-03-10
AU2011211223B2 (en) 2014-10-23
JP5867081B2 (ja) 2016-02-24
US10131672B2 (en) 2018-11-20

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