PL2537856T3 - Sposób przygotowywania octanu atozybanu - Google Patents

Sposób przygotowywania octanu atozybanu

Info

Publication number: PL2537856T3
Authority: PL; Poland
Prior art keywords: atosiban acetate; preparing; preparing atosiban; acetate; atosiban
Prior art date: 2010-12-24

Application number

PL11850254T

Other languages

English (en)

Inventor

Qing Xiao

Jian Liu

Hongling Li

Yaping Ma

Jiancheng Yuan

Original Assignee

Hybio Pharmaceutical Co., Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2010-12-24

Filing date

2011-12-22

Publication date

2018-03-30

2011-12-22 Application filed by Hybio Pharmaceutical Co., Ltd filed Critical Hybio Pharmaceutical Co., Ltd

2018-03-30 Publication of PL2537856T3 publication Critical patent/PL2537856T3/pl

Links

SVDWBHHCPXTODI-QIWYXCRTSA-N acetic acid (2S)-N-[(2S)-5-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16R)-7-(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-16-[(4-ethoxyphenyl)methyl]-10-[(1R)-1-hydroxyethyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide Chemical compound CC(O)=O.C1=CC(OCC)=CC=C1C[C@@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N2[C@@H](CCC2)C(=O)N[C@@H](CCCN)C(=O)NCC(N)=O)CSSCCC(=O)N1 SVDWBHHCPXTODI-QIWYXCRTSA-N 0.000 title 1
229950010486 atosiban acetate Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/16—Oxytocins; Vasopressins; Related peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pregnancy & Childbirth (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Gynecology & Obstetrics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Peptides Or Proteins (AREA)
Saccharide Compounds (AREA)

PL11850254T 2010-12-24 2011-12-22 Sposób przygotowywania octanu atozybanu PL2537856T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
CN2010106047906A CN102127146B (zh)	2010-12-24	2010-12-24	一种制备醋酸阿托西班的方法
PCT/CN2011/084414 WO2012083861A1 (zh)	2010-12-24	2011-12-22	一种制备醋酸阿托西班的方法
EP11850254.1A EP2537856B1 (en)	2010-12-24	2011-12-22	Method for preparing atosiban acetate

Publications (1)

Publication Number	Publication Date
PL2537856T3 true PL2537856T3 (pl)	2018-03-30

Family

ID=44265447

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL11850254T PL2537856T3 (pl)	2010-12-24	2011-12-22	Sposób przygotowywania octanu atozybanu

Country Status (10)

Country	Link
US (1)	US9434767B2 (pl)
EP (1)	EP2537856B1 (pl)
CN (1)	CN102127146B (pl)
DK (1)	DK2537856T3 (pl)
ES (1)	ES2651322T3 (pl)
LT (1)	LT2537856T (pl)
NO (1)	NO2537856T3 (pl)
PL (1)	PL2537856T3 (pl)
PT (1)	PT2537856T (pl)
WO (1)	WO2012083861A1 (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN102127146B (zh) *	2010-12-24	2013-04-24	深圳翰宇药业股份有限公司	一种制备醋酸阿托西班的方法
CN102584953B (zh) *	2012-02-09	2014-01-01	深圳翰宇药业股份有限公司	一种阿托西班的纯化方法
CN104098650B (zh) *	2013-04-15	2019-04-09	中国医学科学院药物研究所	阿托西班的中间体的合成与应用
GB201310921D0 (en) *	2013-06-19	2013-07-31	Chemical & Biopharmaceutical Lab Of Patras S A	Peptide-resin conjugate and use thereof
CN105949283A (zh) *	2016-06-07	2016-09-21	海南合瑞制药股份有限公司	醋酸阿托西班杂质、制备及检测方法
CN106279367B (zh) *	2016-08-15	2019-06-04	海南合瑞制药股份有限公司	一种醋酸阿托西班晶体及其制备方法
CN107312072A (zh) *	2017-06-20	2017-11-03	浙江湃肽生物有限公司	一种纯化分离阿托西班的方法
CN110218242A (zh) *	2019-06-26	2019-09-10	海南中和药业股份有限公司	一种醋酸阿托西班杂质的制备方法
CN111393508B (zh) *	2020-03-26	2023-05-12	上海苏豪逸明制药有限公司	一种阿托西班的制备方法
CN115181157B (zh) *	2021-04-02	2025-08-19	湖北健翔生物制药有限公司	一种固液相结合制备含二硫键多肽的方法
CN116874566B (zh) *	2023-06-06	2025-05-09	天津市药品检验研究院	一种阿托西班烷基化方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10075020I2 (de) *	1982-12-21	2003-01-09	Ferring Ab	Vasotocinderivate
PT710243E (pt) *	1993-06-29	2000-11-30	Ferring Bv	Sintese melhorada de peptidos ciclicos.
ES2336826T3 (es) *	2005-05-03	2010-04-16	Novetide, Ltd.	Procedimientos para la produccion de un peptido que presenta una amida c-terminal.
CN101357937B (zh) *	2007-07-31	2012-11-07	上海苏豪逸明制药有限公司	固相多肽合成阿托西般的制备方法
CN101314613B (zh) *	2008-05-08	2012-04-25	吉尔生化（上海）有限公司	一种阿托西班的固相合成方法
CN102127146B (zh) *	2010-12-24	2013-04-24	深圳翰宇药业股份有限公司	一种制备醋酸阿托西班的方法

2010
- 2010-12-24 CN CN2010106047906A patent/CN102127146B/zh not_active Expired - Fee Related
2011
- 2011-12-22 LT LTEP11850254.1T patent/LT2537856T/lt unknown
- 2011-12-22 DK DK11850254.1T patent/DK2537856T3/en active
- 2011-12-22 PL PL11850254T patent/PL2537856T3/pl unknown
- 2011-12-22 US US13/579,030 patent/US9434767B2/en active Active
- 2011-12-22 EP EP11850254.1A patent/EP2537856B1/en active Active
- 2011-12-22 PT PT118502541T patent/PT2537856T/pt unknown
- 2011-12-22 ES ES11850254.1T patent/ES2651322T3/es active Active
- 2011-12-22 WO PCT/CN2011/084414 patent/WO2012083861A1/zh not_active Ceased
- 2011-12-22 NO NO11850254A patent/NO2537856T3/no unknown

Also Published As

Publication number	Publication date
ES2651322T3 (es)	2018-01-25
CN102127146A (zh)	2011-07-20
DK2537856T3 (en)	2018-01-02
CN102127146B (zh)	2013-04-24
EP2537856A1 (en)	2012-12-26
US9434767B2 (en)	2016-09-06
EP2537856A4 (en)	2013-12-04
EP2537856B1 (en)	2017-09-13
NO2537856T3 (pl)	2018-02-10
WO2012083861A1 (zh)	2012-06-28
US20130261285A1 (en)	2013-10-03
LT2537856T (lt)	2018-01-10
PT2537856T (pt)	2017-12-21

Publication	Publication Date	Title
GB201012605D0 (en)	2010-09-08	Method & system
LT2537856T (lt)	2018-01-10	Atosibano acetato gavimo būdas
EP2600866A4 (en)	2013-12-11	PROCESS FOR THE PRODUCTION OF TUBULYSINES
GB201001833D0 (en)	2010-03-24	Method
EP2558587A4 (en)	2015-05-06	METHOD FOR DISPLAYING ANTIBODIES
GB201007353D0 (en)	2010-06-16	Method
GB201004759D0 (en)	2010-05-05	Method
GB201011513D0 (en)	2010-08-25	Method
GB201007354D0 (en)	2010-06-16	Method
IL223583A (en)	2016-03-31	A method for the production of quinoline-3-carboxamides
ZA201304243B (en)	2018-12-19	Improved connecting method
ZA201207386B (en)	2014-03-26	Process for preparing benzoxaboroles
GB201006306D0 (en)	2010-06-02	Method
GB201012148D0 (en)	2010-09-01	Method
ZA201207291B (en)	2013-06-26	Process for preparing silicon-containing azodicarbamides
ZA201504517B (en)	2016-11-30	Method for preparing methyl acetate
EP2619174A4 (en)	2014-05-14	PROCESS FOR THE PREPARATION OF L-PHENYL-3-DIMETHYLAMINOPROPANE DERIVATIVES
GB201012784D0 (en)	2010-09-15	Method
GB201010855D0 (en)	2010-08-11	Method
IL223145A0 (en)	2013-02-03	Process for preparing dithiine-tetracarboxy-diimides
SI2590940T1 (sl)	2014-12-31	Nov postopek za pripravo ezetimiba
GB201007207D0 (en)	2010-06-16	Method
EP2554659A4 (en)	2013-09-25	PROCESS FOR PREPARING ES CELLS
GB201017003D0 (en)	2010-11-24	Method
GB201007522D0 (en)	2010-06-23	Method