PL2542663T3 - Układ krążenia - Google Patents

Układ krążenia

Info

Publication number
PL2542663T3
PL2542663T3 PL11741408T PL11741408T PL2542663T3 PL 2542663 T3 PL2542663 T3 PL 2542663T3 PL 11741408 T PL11741408 T PL 11741408T PL 11741408 T PL11741408 T PL 11741408T PL 2542663 T3 PL2542663 T3 PL 2542663T3
Authority
PL
Poland
Prior art keywords
circulation system
circulation
Prior art date
Application number
PL11741408T
Other languages
English (en)
Inventor
Uwe Marx
Gerd Lindner
Reyk Horland
Silke Hoffmann
Roland Lauster
Original Assignee
Tissuse Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tissuse Gmbh filed Critical Tissuse Gmbh
Publication of PL2542663T3 publication Critical patent/PL2542663T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/16—Microfluidic devices; Capillary tubes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/10—Hollow fibers or tubes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/06—Nozzles; Sprayers; Spargers; Diffusers
    • C12M29/08—Air lift
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/16—Hollow fibers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/069—Vascular Endothelial cells
    • C12N5/0691—Vascular smooth muscle cells; 3D culture thereof, e.g. models of blood vessels

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Cell Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
PL11741408T 2010-08-06 2011-08-05 Układ krążenia PL2542663T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US37136810P 2010-08-06 2010-08-06
EP10008244 2010-08-06
EP11741408.6A EP2542663B1 (en) 2010-08-06 2011-08-05 Circulation system
PCT/EP2011/003940 WO2012016711A1 (en) 2010-08-06 2011-08-05 Circulation system

Publications (1)

Publication Number Publication Date
PL2542663T3 true PL2542663T3 (pl) 2015-01-30

Family

ID=43414165

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11741408T PL2542663T3 (pl) 2010-08-06 2011-08-05 Układ krążenia

Country Status (13)

Country Link
US (1) US9506024B2 (pl)
EP (1) EP2542663B1 (pl)
JP (1) JP6004442B2 (pl)
CN (1) CN103080296B (pl)
AU (1) AU2011287881B2 (pl)
CA (1) CA2807438C (pl)
DK (1) DK2542663T3 (pl)
EA (1) EA023707B1 (pl)
ES (1) ES2508615T3 (pl)
PL (1) PL2542663T3 (pl)
PT (1) PT2542663E (pl)
SG (1) SG187214A1 (pl)
WO (1) WO2012016711A1 (pl)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102667365B1 (ko) 2008-07-16 2024-05-21 칠드런'즈 메디컬 센터 코포레이션 마이크로채널을 갖는 기관 모방 장치 및 그 사용 및 제조 방법
US9725687B2 (en) 2011-12-09 2017-08-08 President And Fellows Of Harvard College Integrated human organ-on-chip microphysiological systems
EP2628791A1 (de) * 2012-02-17 2013-08-21 Charité - Universitätsmedizin Berlin Perfusionsmodul für die Co-Kultur von Endothelzellen und Glattmuskelzellen zur Bestimmung pathosphysiologischer Veränderungen
EP2634251A1 (en) 2012-02-29 2013-09-04 Technische Universität Berlin 3D in vitro bi-phasic cartilage-bone construct
WO2013134383A1 (en) 2012-03-06 2013-09-12 The Uab Research Foundation Three-dimesional, prevascularized, engineered tissue constructs, methods of making and methods of using the tissue constructs
WO2013159939A1 (en) * 2012-04-26 2013-10-31 Technische Universität Berlin Methods for determining and/or monitoring conditions of a three dimensional cell culture system and optical sensor device for conducting said methods
EP2712918B1 (en) 2012-09-28 2014-11-12 TissUse GmbH Multi-organ-chip with improved life time and homoeostasis
US9580678B2 (en) 2013-06-21 2017-02-28 The Regents Of The University Of California Microfluidic tumor tissue dissociation device
DE102013011768B4 (de) * 2013-07-10 2015-07-23 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Zirkulationssystem sowie Verfahren zur Vitalversorgung von Zellkulturen in einem mikrofluidischen Netzwerk
DE102013114634A1 (de) * 2013-12-20 2015-06-25 Karlsruher Institut für Technologie Mikrofluidischer Bioreaktor mit modularem Aufbau zur Synthese von Zellmetaboliten, das Verfahren zur Nutzung sowie dessen Verwendung
NL2014840B1 (en) * 2015-05-21 2017-01-31 Intecrypt B V Microfluidic device for in vitro 3D cell culture experimentation.
CN108138127A (zh) * 2015-08-14 2018-06-08 通用医疗公司 用于使用在活组织中提供连通的仿生结构的系统和方法
ITUB20153908A1 (it) * 2015-09-25 2017-03-25 Eltek Spa Apparato, sistema e metodo per la disgregazione di un tessuto biologico
CN105498005B (zh) * 2016-01-22 2017-08-11 浙江省人民医院 一种人工肝用去细胞支架生物反应器及其使用方法
US10722540B1 (en) 2016-02-01 2020-07-28 The Regents Of The University Of California Microfluidic device and method for shear stress-induced transformation of cells
KR102231394B1 (ko) * 2016-05-19 2021-03-24 코지 사이토 배양 장치 및 배양 방법, 및 이 배양 방법에 의해 제조된 배양 장기
US11078898B2 (en) * 2016-05-24 2021-08-03 Somavac Medical Solutions, Inc. Portable device with disposable reservoir for collection of internal fluid after surgery
KR20230084308A (ko) * 2016-08-03 2023-06-12 웨이크 포리스트 유니버시티 헬스 사이언시즈 암 모델링 플랫폼 및 그를 사용하는 방법
CN106497784B (zh) * 2016-09-01 2019-03-22 奥凯（苏州）生物技术有限公司 一种实现培养液和废液交换的压力控制系统及其压力控制方法
CN106635790B (zh) * 2016-09-01 2019-02-26 奥凯（苏州）生物技术有限公司 一种全封闭自动化细胞培养系统
CN106497783B (zh) * 2016-09-01 2019-03-22 奥凯（苏州）生物技术有限公司 一种动态循环细胞培养器及细胞培养方法
US10982181B2 (en) * 2016-09-07 2021-04-20 Triad National Security, Llc Devices for cell culture and methods of making and using the same
EP4253956A3 (en) * 2016-10-14 2023-12-06 Wake Forest University Health Sciences Multi-organ "body on a chip" apparatus utilizing a common media
JP6950887B2 (ja) * 2017-04-28 2021-10-13 米満　吉和 体外型の人工肝臓、及び体外型の人工肝臓用又は肝細胞培養用の器具
US10926257B2 (en) * 2017-08-28 2021-02-23 The Regents Of The University Of California Microfluidic device for the digestion of tissues into cellular suspensions
US12036550B2 (en) * 2017-08-28 2024-07-16 The Regents Of The University Of California Microfluidic device for the digestion of tissues into cellular suspensions
JP7763450B2 (ja) 2018-02-02 2025-11-04 ウェイク・フォレスト・ユニバーシティ・ヘルス・サイエンシーズ 免疫療法に関するオルガノイドならびにそれを調製および使用する方法
US12558689B2 (en) 2018-03-12 2026-02-24 North Carolina State University Vascular development monitoring systems and uses thereof
WO2019191111A1 (en) 2018-03-26 2019-10-03 The Trustees Of The University Of Pennsylvania Systems and methods for multilane vasculature
CN117752862A (zh) * 2018-05-25 2024-03-26 通用医疗公司 复杂可植入维生装置的增材制造
RU192234U1 (ru) * 2018-06-29 2019-09-09 Общество с ограниченной ответственностью "Микрофлюидные технологии" Проточный чип для моделирования участка сосудистого русла для испытания имплантатов и оборудования для сердечно-сосудистой хирургии
FI3666883T3 (fi) 2018-12-12 2025-05-13 Zhongke Xinray Suzhou Biological Tech Co Limited Menetelmä endoteelin glykokalyksiin liittyviä sairauksia vastaan ennaltaehkäisevän ja terapeuttisen vaikutuksen omaavien yhdisteiden seulomiseksi
KR102267433B1 (ko) * 2019-07-29 2021-06-21 연세대학교 산학협력단 세포배양 플레이트
KR102830487B1 (ko) 2020-01-16 2025-07-08 삼성전자주식회사 세포 클러스터를 이용한 생체 전자약 장치
US12584086B2 (en) 2020-03-30 2026-03-24 Javelin Biotech, Inc. Microfluidic devices and methods of designing and using microfluidic devices
KR102222074B1 (ko) * 2020-04-28 2021-03-03 (주)아크에이르 장기 칩 시험 시스템
US20230313106A1 (en) * 2020-04-30 2023-10-05 Xingyue Peng Method for constructing slow microcyclic artificial cell niche and apparatus thereof
CN116726720B (zh) * 2023-07-12 2025-09-09 天津市第三中心医院 一种具有仿生自抗凝功能的血浆分离膜及其制备方法
DE102023210990B3 (de) * 2023-11-07 2025-04-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung eingetragener Verein Mikrofluidisches Zirkulationssystem, Verwendung eines mikrofluidischen Zirkulationssystems und Vorrichtung zur Kultivierung von biologischen Zellen
CN118566453B (zh) * 2024-08-02 2024-10-25 天津城建大学 一种模拟体内动态循环的微流控药物分析系统
CN121628813A (zh) * 2026-02-03 2026-03-10 江西中医药大学附属医院 一种基于毛细管培养类器官的方法及装置

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4218917C2 (de) 1992-06-10 1996-07-11 Schmitz Klaus Peter Dr Ing Hab Zellkulturmatrix
WO2000066036A2 (en) 1999-04-30 2000-11-09 Massachusetts General Hospital Fabrication of vascularized tissue using microfabricated two-dimensional molds
WO2002053193A2 (en) * 2001-01-02 2002-07-11 The Charles Stark Draper Laboratory, Inc. Tissue engineering of three-dimensional vascularized using microfabricated polymer assembly technology
GB0121986D0 (en) * 2001-09-11 2001-10-31 Isis Innovation Method and structure for growing living organic tissue
US7645253B2 (en) * 2001-11-16 2010-01-12 National Quality Care, Inc. Wearable ultrafiltration device
US7622298B2 (en) * 2006-03-24 2009-11-24 Norits, Inc. Method for creating perfusable microvessel systems
DE102006031871B4 (de) * 2006-07-10 2008-10-23 Gerlach, Jörg, Dr.med. 3-D Petri-Schale zur Züchtung und Untersuchung von Zellen

Also Published As

Publication number Publication date
WO2012016711A1 (en) 2012-02-09
SG187214A1 (en) 2013-02-28
US9506024B2 (en) 2016-11-29
CN103080296B (zh) 2015-03-25
EP2542663B1 (en) 2014-07-16
AU2011287881B2 (en) 2014-07-24
CA2807438A1 (en) 2012-02-09
DK2542663T3 (da) 2014-10-13
US20130295598A1 (en) 2013-11-07
JP2013532484A (ja) 2013-08-19
ES2508615T3 (es) 2014-10-16
HK1180715A1 (en) 2013-10-25
EA201390147A1 (ru) 2013-08-30
EP2542663A1 (en) 2013-01-09
CA2807438C (en) 2020-09-01
EA023707B1 (ru) 2016-07-29
AU2011287881A1 (en) 2013-02-14
CN103080296A (zh) 2013-05-01
JP6004442B2 (ja) 2016-10-05
PT2542663E (pt) 2014-10-07

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