PL254621A1 - Method of obtaining 6 alpha-methylstereoides - Google Patents

Method of obtaining 6 alpha-methylstereoides

Info

Publication number
PL254621A1
PL254621A1 PL25462185A PL25462185A PL254621A1 PL 254621 A1 PL254621 A1 PL 254621A1 PL 25462185 A PL25462185 A PL 25462185A PL 25462185 A PL25462185 A PL 25462185A PL 254621 A1 PL254621 A1 PL 254621A1
Authority
PL
Poland
Prior art keywords
methylstereoides
alpha
obtaining
Prior art date
Application number
PL25462185A
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of PL254621A1 publication Critical patent/PL254621A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/0045—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Steroid Compounds (AREA)
PL25462185A 1984-07-23 1985-07-19 Method of obtaining 6 alpha-methylstereoides PL254621A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843427486 DE3427486A1 (en) 1984-07-23 1984-07-23 METHOD FOR PRODUCING 6 (ALPHA) METHYLSTEROIDS

Publications (1)

Publication Number Publication Date
PL254621A1 true PL254621A1 (en) 1986-06-17

Family

ID=6241571

Family Applications (1)

Application Number Title Priority Date Filing Date
PL25462185A PL254621A1 (en) 1984-07-23 1985-07-19 Method of obtaining 6 alpha-methylstereoides

Country Status (5)

Country Link
EP (1) EP0187847A1 (en)
JP (1) JPS61502960A (en)
DE (1) DE3427486A1 (en)
PL (1) PL254621A1 (en)
WO (1) WO1986000907A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1317283C (en) * 1986-11-05 1993-05-04 Douglas Alan Livingston Steroidal 17–-silyl ethers and process to corticoids and progesterones
DE3931064A1 (en) * 1989-09-14 1991-03-28 Schering Ag METHOD FOR PRODUCING PROGESTERONE DERIVATIVES
US5972922A (en) * 1990-06-11 1999-10-26 Alcon Laboratories, Inc. Steroids which inhibit angiogenesis
JPH10500946A (en) * 1994-05-09 1998-01-27 ファルマシア・アンド・アップジョン・カンパニー Synthesis of 17β-cyano-3-ethoxy-17α-hydroxy-6-methylandrosta-3,5,9 (11) -triene
CN100560201C (en) * 2006-12-13 2009-11-18 天津天药药业股份有限公司 Preparation method of steroid 6-methine stereoselective hydrogenation reaction catalyst
WO2011130877A1 (en) * 2010-04-21 2011-10-27 天津金耀集团有限公司 Crystalline form of methylprednisolone aceponate monohydrate and preparation methods thereof
CN103601786A (en) * 2013-11-22 2014-02-26 湖南新合新生物医药有限公司 Preparation method of methylprednisolone key intermediate
CN105017364A (en) * 2015-07-06 2015-11-04 湖南新合新生物医药有限公司 Methylprednisolone intermediate, preparation method therefor and application thereof
CN111748010B (en) * 2019-03-29 2023-12-08 天津药业研究院股份有限公司 Methylprednisolone aceponate anhydrous crystal type and composition thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE12237T1 (en) * 1980-12-23 1985-04-15 Schering Ag NEW 6-ALPHA-METHYLHYDROCORTISONE DERIVATIVES, THEIR PREPARATION AND USE.
EP0153001B1 (en) * 1984-02-03 1992-03-11 The Upjohn Company Steroids having an enamide or enimide group and their preparation
JPH08262296A (en) * 1995-03-23 1996-10-11 Mitsubishi Cable Ind Ltd Optical fiber cable

Also Published As

Publication number Publication date
EP0187847A1 (en) 1986-07-23
DE3427486A1 (en) 1986-01-30
WO1986000907A1 (en) 1986-02-13
JPS61502960A (en) 1986-12-18

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