PL2553090T3 - Termostabilne warianty fitazy - Google Patents

Termostabilne warianty fitazy

Info

Publication number
PL2553090T3
PL2553090T3 PL11709966T PL11709966T PL2553090T3 PL 2553090 T3 PL2553090 T3 PL 2553090T3 PL 11709966 T PL11709966 T PL 11709966T PL 11709966 T PL11709966 T PL 11709966T PL 2553090 T3 PL2553090 T3 PL 2553090T3
Authority
PL
Poland
Prior art keywords
phytase variants
thermostable phytase
thermostable
variants
phytase
Prior art date
Application number
PL11709966T
Other languages
English (en)
Inventor
Lars Kobberoee Skov
Leonardo De Maria
Tomoko Matsui
Original Assignee
Novozymes A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes A/S filed Critical Novozymes A/S
Publication of PL2553090T3 publication Critical patent/PL2553090T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/195Proteins from microorganisms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06Ethanol, i.e. non-beverage
    • C12P7/14Multiple stages of fermentation; Multiple types of microorganisms or re-use of microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/03Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/030083-Phytase (3.1.3.8)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/03Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/030264-Phytase (3.1.3.26), i.e. 6-phytase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/03Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/030725-Phytase (3.1.3.72)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Husbandry (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physiology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL11709966T 2010-03-26 2011-03-25 Termostabilne warianty fitazy PL2553090T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10158027 2010-03-26
EP11709966.3A EP2553090B1 (en) 2010-03-26 2011-03-25 Thermostable phytase variants
PCT/EP2011/054639 WO2011117396A2 (en) 2010-03-26 2011-03-25 Thermostable phytase variants

Publications (1)

Publication Number Publication Date
PL2553090T3 true PL2553090T3 (pl) 2019-08-30

Family

ID=44123229

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11709966T PL2553090T3 (pl) 2010-03-26 2011-03-25 Termostabilne warianty fitazy

Country Status (10)

Country Link
US (2) US20130195829A1 (pl)
EP (1) EP2553090B1 (pl)
CN (1) CN102906254A (pl)
AU (1) AU2011231562B2 (pl)
BR (1) BR112012023840B1 (pl)
CA (2) CA2794095C (pl)
DK (1) DK2553090T3 (pl)
ES (1) ES2723050T3 (pl)
PL (1) PL2553090T3 (pl)
WO (1) WO2011117396A2 (pl)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2617822A3 (en) 2006-09-21 2013-10-16 Verenium Corporation Phytases, nucleic acids encoding them and methods for making and using them
TW201234978A (en) 2011-02-18 2012-09-01 Danisco Feed additive composition
GB201102857D0 (en) 2011-02-18 2011-04-06 Danisco Feed additive composition
GB201102865D0 (en) 2011-02-18 2011-04-06 Danisco Feed additive composition
ES2705533T3 (es) 2011-07-07 2019-03-25 Dupont Nutrition Biosci Aps Ensayo
GB201213801D0 (en) 2012-08-03 2012-09-12 Dupont Nutrition Biosci Aps Feed additive composition
GB201308828D0 (en) 2013-03-12 2013-07-03 Verenium Corp Phytase
GB201308843D0 (en) * 2013-03-14 2013-07-03 Verenium Corp Phytase formulation
EP2799531A1 (de) 2013-05-03 2014-11-05 Clariant Produkte (Deutschland) GmbH Einsatz von Phosphatasen zur enzymatischen Entschleimung von Triglyceriden
CA2919437A1 (en) 2013-07-25 2015-01-29 Basf Enzymes Llc Phytase
KR102349256B1 (ko) 2013-08-09 2022-01-07 바이오메디슨, 인코퍼레이티드 개선된 민감성을 지닌 보툴리눔 독소 검정
CN104450643B (zh) * 2014-12-19 2020-07-28 青岛蔚蓝生物集团有限公司 植酸酶突变体及其应用
TWI607088B (zh) * 2016-02-18 2017-12-01 基酵生物科技股份有限公司 提升耐熱性的植酸酶
TWI616532B (zh) * 2016-02-18 2018-03-01 基酵生物科技股份有限公司 提升耐熱性的植酸酶
TWI591180B (zh) 2016-02-18 2017-07-11 基酵生物科技股份有限公司 提升耐熱性的植酸酶
TWI615471B (zh) * 2016-02-18 2018-02-21 基酵生物科技股份有限公司 提升耐熱性的植酸酶
CN110129300B (zh) * 2016-06-02 2021-08-03 天津科技大学 一种磷脂酶d
MX2020008302A (es) 2018-02-08 2020-10-14 Danisco Us Inc Partículas de matriz de cera térmicamente resistentes para encapsulación de enzimas.
MX2020011305A (es) 2018-04-26 2021-01-08 Danisco Us Inc Método para aumentar la estabilidad de una fitasa en una composición sólida y una composición granulada que comprende fosfato y fitasa.
CN118440920A (zh) * 2018-05-30 2024-08-06 南京百斯杰生物工程有限公司 植酸酶突变体
BR112022000351A2 (pt) 2019-07-09 2022-05-10 Dupont Nutrition Biosci Aps Composições de enzima particuladas revestidas de gordura
CN114615894B (zh) 2019-08-16 2024-09-06 国际N&H丹麦有限公司 包含乳杆菌菌株组合的用于消化道健康的组合物
WO2021046073A1 (en) 2019-09-05 2021-03-11 Dupont Nutrition Biosciences Aps Feed composition
BR112022007613A2 (pt) 2019-10-21 2022-08-23 Dupont Nutrition Biosci Aps Composição para a saúde do intestino
CN115867146B (zh) 2020-02-07 2025-01-17 国际N&H丹麦有限公司 用于动物健康的饲料组合物
CN116209766A (zh) * 2020-08-13 2023-06-02 诺维信公司 植酸酶变体和编码其的多核苷酸
EP4196575A1 (en) 2020-08-13 2023-06-21 Novozymes A/S Phytase variants and polynucleotides encoding same
CN117241678A (zh) 2020-10-16 2023-12-15 杜邦营养生物科学有限公司 用于动物健康的饲料组合物
WO2022169933A2 (en) 2021-02-03 2022-08-11 Dupont Nutrition Biosciences Aps Compositions for gut health
AU2022349014A1 (en) 2021-09-27 2024-04-04 International N&H Denmark Aps Feed additive compositions and methods for using the same
WO2024227153A1 (en) 2023-04-28 2024-10-31 International N&H Denmark Aps Ruminant feed additive compositions
WO2025059013A1 (en) 2023-09-11 2025-03-20 International N&H Denmark Aps Bacillus-based components for inhibiting or delaying the growth of enterococcus spp. in animals
WO2025217017A1 (en) 2024-04-08 2025-10-16 Novozymes A/S Compositions and methods for increasing phosphorous availability

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7442398B2 (en) * 2003-03-25 2008-10-28 Republic Of National Fisheries Research And Development Institute Phytase produced from Citrobacter braakii
AR050895A1 (es) 2004-10-04 2006-11-29 Novozymes As Polipeptidos que tienen actividad de fitasa y polinucleotidos que los codifican
GB0422052D0 (en) * 2004-10-04 2004-11-03 Dansico As Enzymes
PL1797178T3 (pl) 2004-10-04 2013-02-28 Dupont Nutrition Biosci Aps Fitaza pochodząca od Citrobacter freundii i jej homologi
EP2272964A3 (en) * 2004-10-04 2011-08-31 Novozymes A/S Polypeptides having phytase activity and polynucleotides encoding same
WO2007112739A1 (en) * 2006-04-04 2007-10-11 Novozymes A/S Phytase variants
US8540984B2 (en) * 2006-08-03 2013-09-24 Cornell Research Foundation, Inc. Phytases with improved thermal stability
CN101594774A (zh) * 2007-01-30 2009-12-02 诺维信公司 具有肌醇六磷酸酶活性的多肽和编码该多肽的多核苷酸
DK2129781T3 (da) * 2007-03-26 2014-03-31 Novozymes As Hafnia-phytase
AU2008352003B2 (en) * 2007-12-03 2014-05-08 Agrivida, Inc. Engineering enzymatically susceptible phytases
WO2010034835A2 (en) * 2008-09-26 2010-04-01 Novozymes A/S Hafnia phytase variants
FR2947563B1 (fr) * 2009-07-01 2015-08-21 Biomethodes Variants ameliores d'une phytase
US8334124B1 (en) * 2009-09-23 2012-12-18 The United States Of America As Represented By The Secretary Of Agriculture Modified Aspergillus niger phytase
RU2567000C2 (ru) * 2009-10-22 2015-10-27 Басф Се Фитаза, ее применение, корм и кормовая добавка для животных, содержащие ее
CN102906255A (zh) * 2010-03-26 2013-01-30 诺维信公司 热稳定性肌醇六磷酸酶变体
EP2552232B1 (en) * 2010-03-26 2016-07-06 Novozymes A/S Thermostable phytase variants
TW201234978A (en) * 2011-02-18 2012-09-01 Danisco Feed additive composition
CN103502443B (zh) * 2011-04-21 2016-05-04 巴斯夫欧洲公司 合成的植酸酶变体

Also Published As

Publication number Publication date
ES2723050T3 (es) 2019-08-21
US20130195829A1 (en) 2013-08-01
WO2011117396A3 (en) 2011-11-24
US20150159149A1 (en) 2015-06-11
US9611469B2 (en) 2017-04-04
EP2553090B1 (en) 2019-02-27
DK2553090T3 (da) 2019-05-13
WO2011117396A2 (en) 2011-09-29
EP2553090A2 (en) 2013-02-06
BR112012023840A2 (pt) 2020-07-28
CA3105079C (en) 2026-02-24
AU2011231562A1 (en) 2012-09-27
AU2011231562B2 (en) 2015-10-22
BR112012023840B1 (pt) 2021-06-22
CN102906254A (zh) 2013-01-30
CA2794095A1 (en) 2011-09-29
CA2794095C (en) 2021-02-16
CA3105079A1 (en) 2011-09-29

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