PL2563932T3 - Wykrywanie komórek odpornościowych, w szczególności komórek T poprzez analizę metylacji DNA genów CCR6 - Google Patents
Wykrywanie komórek odpornościowych, w szczególności komórek T poprzez analizę metylacji DNA genów CCR6Info
- Publication number
- PL2563932T3 PL2563932T3 PL11716573T PL11716573T PL2563932T3 PL 2563932 T3 PL2563932 T3 PL 2563932T3 PL 11716573 T PL11716573 T PL 11716573T PL 11716573 T PL11716573 T PL 11716573T PL 2563932 T3 PL2563932 T3 PL 2563932T3
- Authority
- PL
- Poland
- Prior art keywords
- cells
- ccr6
- genes
- dna
- detection
- Prior art date
Links
- 230000007067 DNA methylation Effects 0.000 title 1
- 210000001744 T-lymphocyte Anatomy 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 210000002865 immune cell Anatomy 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2523/00—Reactions characterised by treatment of reaction samples
- C12Q2523/10—Characterised by chemical treatment
- C12Q2523/125—Bisulfite(s)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32922910P | 2010-04-29 | 2010-04-29 | |
| EP11716573.8A EP2563932B1 (en) | 2010-04-29 | 2011-04-29 | Detection of immune cells, in particular t cells through dna-methylation analysis of the genes ccr6 |
| PCT/EP2011/056871 WO2011135088A1 (en) | 2010-04-29 | 2011-04-29 | Detection of immune cells, in particular t cells through dna-methylation analysis of the genes ccr6 and blr1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2563932T3 true PL2563932T3 (pl) | 2018-07-31 |
Family
ID=44022865
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL11716573T PL2563932T3 (pl) | 2010-04-29 | 2011-04-29 | Wykrywanie komórek odpornościowych, w szczególności komórek T poprzez analizę metylacji DNA genów CCR6 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9783846B2 (pl) |
| EP (1) | EP2563932B1 (pl) |
| JP (2) | JP6062850B2 (pl) |
| DK (1) | DK2563932T3 (pl) |
| ES (1) | ES2657846T3 (pl) |
| PL (1) | PL2563932T3 (pl) |
| WO (1) | WO2011135088A1 (pl) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20170233807A1 (en) | 2008-12-16 | 2017-08-17 | Epiontis Gmbh | Epigenetic Markers for the Identification of Blood Sub-cells of Type 1 |
| WO2011135088A1 (en) * | 2010-04-29 | 2011-11-03 | Epiontis Gmbh | Detection of immune cells, in particular t cells through dna-methylation analysis of the genes ccr6 and blr1 |
| WO2012054509A2 (en) * | 2010-10-22 | 2012-04-26 | Dana-Farber Cancer Institute, Inc. | Discovery of regulatory t cells programmed to suppress an immune response |
| US10548957B2 (en) | 2012-09-28 | 2020-02-04 | Dana-Farber Cancer Institute, Inc. | Targeted expansion of Qa-1-peptide-specific regulatory CD8 T cells to ameliorate arthritis |
| US10208346B2 (en) | 2013-04-19 | 2019-02-19 | Epiontis Gmbh | Method for identifying the quantitative cellular composition in a biological sample |
| US20170269076A1 (en) | 2014-08-27 | 2017-09-21 | Dana-Farber Cancer Institute, Inc. | Intracellular osteopontin regulates the lineage commitment of lymphoid subsets |
| KR20190006952A (ko) * | 2016-03-31 | 2019-01-21 | 라이언 티씨알 피티이. 리미티드 | 외인성 바이러스-특이적 t 세포 수용체 (tcr)를 발현하는 비-활성화된 t 세포 |
| EP3494210B1 (en) * | 2016-08-05 | 2024-10-09 | The Regents Of The University Of California | Dna methylation based predictor of mortality |
| DE102018112644B4 (de) * | 2018-05-25 | 2020-06-10 | Epiontis Gmbh | CXCR3 als epigenetischer Marker zur Identifizierung von inflammatorischen Immunzellen, insbesondere CD8+ Gedächnis-T-Zellen |
| WO2020170231A1 (en) * | 2019-02-22 | 2020-08-27 | St. Jude Children's Research Hospital | Methods for identifying and improving t cell multipotency |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6110695A (en) | 1997-12-02 | 2000-08-29 | The Regents Of The University Of California | Modulating the interaction of the chemokine, B Lymphocyte Hemoattractant, and its Receptor, BLR1 |
| WO2003014153A2 (en) | 2001-08-10 | 2003-02-20 | Topigen Pharmaceutique Inc. | Cellular virus receptors and methods of use. |
| CA2555704A1 (en) * | 2004-02-10 | 2005-08-25 | Cornell Research Foundation, Inc. | Method for detection of promoter methylation status |
| WO2011135088A1 (en) * | 2010-04-29 | 2011-11-03 | Epiontis Gmbh | Detection of immune cells, in particular t cells through dna-methylation analysis of the genes ccr6 and blr1 |
-
2011
- 2011-04-29 WO PCT/EP2011/056871 patent/WO2011135088A1/en not_active Ceased
- 2011-04-29 ES ES11716573.8T patent/ES2657846T3/es active Active
- 2011-04-29 EP EP11716573.8A patent/EP2563932B1/en active Active
- 2011-04-29 DK DK11716573.8T patent/DK2563932T3/en active
- 2011-04-29 JP JP2013506682A patent/JP6062850B2/ja not_active Expired - Fee Related
- 2011-04-29 PL PL11716573T patent/PL2563932T3/pl unknown
- 2011-04-29 US US13/636,556 patent/US9783846B2/en active Active
-
2016
- 2016-05-27 JP JP2016106050A patent/JP2016208977A/ja active Pending
-
2017
- 2017-07-27 US US15/661,432 patent/US10590475B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US9783846B2 (en) | 2017-10-10 |
| JP6062850B2 (ja) | 2017-01-25 |
| EP2563932B1 (en) | 2017-11-29 |
| WO2011135088A1 (en) | 2011-11-03 |
| US20130089861A1 (en) | 2013-04-11 |
| JP2013524828A (ja) | 2013-06-20 |
| JP2016208977A (ja) | 2016-12-15 |
| US20170327871A1 (en) | 2017-11-16 |
| DK2563932T3 (en) | 2018-03-05 |
| ES2657846T3 (es) | 2018-03-07 |
| US10590475B2 (en) | 2020-03-17 |
| EP2563932A1 (en) | 2013-03-06 |
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