PL2590949T3 - Sposób wytwarzania chinolino-3-karboksyamidów - Google Patents

Sposób wytwarzania chinolino-3-karboksyamidów

Info

Publication number: PL2590949T3
Authority: PL; Poland
Prior art keywords: carboxamides; quinoline; manufacturing
Prior art date: 2010-07-09

Application number

PL11732421T

Other languages

English (en)

Inventor

Lillemor Maria Bock

Pär Henning Holmberg

Karl-Erik Jansson

Original Assignee

Active Biotech Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2010-07-09

Filing date

2011-07-07

Publication date

2016-06-30

2011-07-07 Application filed by Active Biotech Ab filed Critical Active Biotech Ab

2016-06-30 Publication of PL2590949T3 publication Critical patent/PL2590949T3/pl

Links

ACBLGRAOCIXXAL-UHFFFAOYSA-N Quinoline-3-carboxamides Chemical class C12=CC(C=3C=CN=CC=3)=CC=C2C(=O)C(C(=O)N)=CN1C1=CC=C(F)C=C1 ACBLGRAOCIXXAL-UHFFFAOYSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
238000000034 method Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Quinoline Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

PL11732421T 2010-07-09 2011-07-07 Sposób wytwarzania chinolino-3-karboksyamidów PL2590949T3 (pl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US36284910P	2010-07-09	2010-07-09
EP10169162		2010-07-09
PCT/EP2011/061490 WO2012004338A1 (en)	2010-07-09	2011-07-07	Method for manufacturing of quinoline-3-carboxamides
EP11732421.0A EP2590949B1 (en)	2010-07-09	2011-07-07	Method for manufacturing of quinoline-3-carboxamides

Publications (1)

Publication Number	Publication Date
PL2590949T3 true PL2590949T3 (pl)	2016-06-30

Family

ID=43348982

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL11732421T PL2590949T3 (pl)	2010-07-09	2011-07-07	Sposób wytwarzania chinolino-3-karboksyamidów

Country Status (20)

Country	Link
US (1)	US8871936B2 (pl)
EP (1)	EP2590949B1 (pl)
JP (1)	JP5881691B2 (pl)
KR (1)	KR101855195B1 (pl)
CN (1)	CN103119023B (pl)
AU (1)	AU2011275720B2 (pl)
BR (1)	BR112012033465A2 (pl)
CA (1)	CA2802006C (pl)
DK (1)	DK2590949T5 (pl)
EA (1)	EA021171B1 (pl)
ES (1)	ES2563208T3 (pl)
IL (1)	IL223583A (pl)
MX (1)	MX2013000288A (pl)
NZ (1)	NZ604176A (pl)
PL (1)	PL2590949T3 (pl)
PT (1)	PT2590949E (pl)
SG (1)	SG186430A1 (pl)
UA (1)	UA108381C2 (pl)
WO (1)	WO2012004338A1 (pl)
ZA (1)	ZA201209370B (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN103626701A (zh) *	2012-08-28	2014-03-12	天津药物研究院	一种制备喹啉衍生物的方法
CN103626702A (zh) *	2012-08-30	2014-03-12	天津药物研究院	一种制备喹啉酮衍生物的方法
CN105367492B (zh) *	2014-08-28	2018-07-03	杭州普晒医药科技有限公司	他喹莫德的晶型及其制备方法、其药物组合物和用途
EP3041472B1 (en)	2014-09-23	2017-02-01	Active Biotech AB	Quinoline carboxamides for use in the treatment of multiple myeloma
BR112017009854B1 (pt)	2014-11-19	2022-08-23	Active Biotech Ab	Uso do composto 4-hidroxi-5-metoxi-n,1-dimetil-2-oxo-n-[4-(trifluorometil)fenil]-1,2-dihidroquinolina-3-carboxamida (tasquinimod) ou um sal farmaceuticamente aceitável do mesmo para o tratamento de leucemia
KR101807124B1 (ko) *	2015-12-02	2017-12-07	현대자동차 주식회사	연료전지차량의 비상 운전 제어 방법
KR102978225B1 (ko)	2020-03-03	2026-06-15	액티브 바이오테크 에이비	조합 요법에 사용하기 위한 타스퀴니모드 또는 이의 약학적으로 허용가능한 염
CN111732540B (zh) *	2020-07-20	2020-11-13	湖南速博生物技术有限公司	一种罗喹美克的制备方法
US20230293512A1 (en)	2020-07-23	2023-09-21	Erasmus University Medical Center Rotterdam	S100 proteins as novel therapeutic targets in myeloproliferative neoplasms
WO2022152902A1 (en)	2021-01-18	2022-07-21	Active Biotech Ab	Tasquinimod or a pharmaceutically acceptable salt thereof for use in the treatment of myelodysplastic syndrome
KR20240012436A (ko)	2021-05-25	2024-01-29	액티브 바이오테크 에이비	복수의 타스퀴니모드 입자 및 그 용도
CA3221689A1 (en) *	2021-07-02	2023-01-05	Hans Wannman	A pharmaceutical product containing tasquinimod and a method for assessing the purity of said product
KR102815351B1 (ko)	2022-04-20	2025-05-29	국립목포대학교산학협력단	판막 석회화 예방 또는 치료용 조성물

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3769292A (en) *	1972-04-28	1973-10-30	Warner Lambert Co	N-(pyridyl)2h 1-benzothiopyran-3-carboxamide-4-hydroxy 1,1-dioxides
US3868379A (en) *	1972-04-28	1975-02-25	Warner Lambert Co	Heterocyclic amides of 4-hydroxy-2H-1-benzothiopyran-3-carboxylic acid 1,1-dioxide
AT345847B (de) *	1974-11-08	1978-10-10	Thomae Gmbh Dr K	Verfahren zur herstellung neuer 4-hydroxy-2h- naphtho- (2,1-e)-1,2-thiazin-3-carboxamid-1,1-dioxid und deren salze
US4786644A (en) *	1987-11-27	1988-11-22	Hoechst-Roussel Pharmaceuticals Inc.	1-aryl-3-quinolinecarboxamide
US5912349A (en)	1997-01-31	1999-06-15	Pharmacia & Upjohn Company	Process for the preparation of roquinimex
US6077851A (en)	1998-04-27	2000-06-20	Active Biotech Ab	Quinoline derivatives
SE9801474D0 (sv) *	1998-04-27	1998-04-27	Active Biotech Ab	Quinoline Derivatives
US6133285A (en)	1998-07-15	2000-10-17	Active Biotech Ab	Quinoline derivatives
SE0201778D0 (sv) *	2002-06-12	2002-06-12	Active Biotech Ab	Process for the manufacture of quinoline derivatives
US6875869B2 (en)	2002-06-12	2005-04-05	Active Biotech Ab	Process for the manufacture of quinoline derivatives
US7560557B2 (en) *	2002-06-12	2009-07-14	Active Biotech Ag	Process for the manufacture of quinoline derivatives
JP2011512357A (ja) *	2008-02-15	2011-04-21	メルク・シャープ・エンド・ドーム・コーポレイション	縮合ピリドンｍ１受容体ポジティブアロステリックモジュレーター
PL2276740T3 (pl) *	2008-04-28	2015-01-30	Actavis Group Ptc Ehf	Ulepszony sposób wytwarzania pochodnych chinolino-3-karboksyamidowych

2011
- 2011-07-07 WO PCT/EP2011/061490 patent/WO2012004338A1/en not_active Ceased
- 2011-07-07 DK DK11732421.0T patent/DK2590949T5/en active
- 2011-07-07 AU AU2011275720A patent/AU2011275720B2/en not_active Ceased
- 2011-07-07 PT PT117324210T patent/PT2590949E/pt unknown
- 2011-07-07 JP JP2013517387A patent/JP5881691B2/ja not_active Expired - Fee Related
- 2011-07-07 US US13/809,233 patent/US8871936B2/en active Active
- 2011-07-07 NZ NZ604176A patent/NZ604176A/en not_active IP Right Cessation
- 2011-07-07 EA EA201300103A patent/EA021171B1/ru not_active IP Right Cessation
- 2011-07-07 CA CA2802006A patent/CA2802006C/en active Active
- 2011-07-07 ES ES11732421.0T patent/ES2563208T3/es active Active
- 2011-07-07 UA UAA201300947A patent/UA108381C2/uk unknown
- 2011-07-07 BR BR112012033465A patent/BR112012033465A2/pt not_active Application Discontinuation
- 2011-07-07 SG SG2012094371A patent/SG186430A1/en unknown
- 2011-07-07 MX MX2013000288A patent/MX2013000288A/es active IP Right Grant
- 2011-07-07 KR KR1020137001660A patent/KR101855195B1/ko not_active Expired - Fee Related
- 2011-07-07 EP EP11732421.0A patent/EP2590949B1/en active Active
- 2011-07-07 CN CN201180033827.7A patent/CN103119023B/zh not_active Expired - Fee Related
- 2011-07-07 PL PL11732421T patent/PL2590949T3/pl unknown
2012
- 2012-12-11 ZA ZA2012/09370A patent/ZA201209370B/en unknown
- 2012-12-12 IL IL223583A patent/IL223583A/en active IP Right Grant

Also Published As

Publication number	Publication date
UA108381C2 (uk)	2015-04-27
IL223583A (en)	2016-03-31
CA2802006A1 (en)	2012-01-12
CN103119023B (zh)	2014-12-24
SG186430A1 (en)	2013-01-30
DK2590949T5 (en)	2016-05-23
CN103119023A (zh)	2013-05-22
US20130109860A1 (en)	2013-05-02
EA201300103A1 (ru)	2013-06-28
EA021171B1 (ru)	2015-04-30
US8871936B2 (en)	2014-10-28
ES2563208T3 (es)	2016-03-11
EP2590949B1 (en)	2015-11-25
KR20130091730A (ko)	2013-08-19
JP2013529672A (ja)	2013-07-22
BR112012033465A2 (pt)	2017-06-20
ZA201209370B (en)	2014-03-26
CA2802006C (en)	2018-09-25
WO2012004338A1 (en)	2012-01-12
HK1183864A1 (zh)	2014-01-10
MX2013000288A (es)	2013-05-22
AU2011275720A1 (en)	2013-01-10
NZ604176A (en)	2014-10-31
JP5881691B2 (ja)	2016-03-09
KR101855195B1 (ko)	2018-05-08
EP2590949A1 (en)	2013-05-15
DK2590949T3 (en)	2016-02-29
PT2590949E (pt)	2016-03-07
AU2011275720B2 (en)	2015-05-14

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