PL2601195T3 - Tandemowy sposób wytwarzania n-alkilomorfinanów - Google Patents

Tandemowy sposób wytwarzania n-alkilomorfinanów

Info

Publication number
PL2601195T3
PL2601195T3 PL11746371T PL11746371T PL2601195T3 PL 2601195 T3 PL2601195 T3 PL 2601195T3 PL 11746371 T PL11746371 T PL 11746371T PL 11746371 T PL11746371 T PL 11746371T PL 2601195 T3 PL2601195 T3 PL 2601195T3
Authority
PL
Poland
Prior art keywords
preparing
tandem process
morphinans
alkyl
alkyl morphinans
Prior art date
Application number
PL11746371T
Other languages
English (en)
Inventor
Subo Liao
Peter X Wang
David W Berberich
Douglas C Miller
Original Assignee
Mallinckrodt Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Llc filed Critical Mallinckrodt Llc
Publication of PL2601195T3 publication Critical patent/PL2601195T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL11746371T 2010-08-04 2011-08-03 Tandemowy sposób wytwarzania n-alkilomorfinanów PL2601195T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37062810P 2010-08-04 2010-08-04
EP11746371.1A EP2601195B1 (en) 2010-08-04 2011-08-03 Tandem process for preparing n-alkyl morphinans
PCT/US2011/046344 WO2012018871A1 (en) 2010-08-04 2011-08-03 Tandem process for preparing n-alkyl morphinans

Publications (1)

Publication Number Publication Date
PL2601195T3 true PL2601195T3 (pl) 2014-10-31

Family

ID=44515014

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11746371T PL2601195T3 (pl) 2010-08-04 2011-08-03 Tandemowy sposób wytwarzania n-alkilomorfinanów

Country Status (8)

Country Link
US (1) US8703949B2 (pl)
EP (1) EP2601195B1 (pl)
JP (1) JP2013532730A (pl)
AU (1) AU2011285839B2 (pl)
CA (1) CA2806620A1 (pl)
ES (1) ES2465340T3 (pl)
PL (1) PL2601195T3 (pl)
WO (1) WO2012018871A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112016010098A2 (pt) * 2013-11-18 2021-07-06 Mallinckrodt Llc Preparação de normorfinanos
CN105294711B (zh) * 2014-05-30 2018-04-13 复旦大学 一种稠环吗啡类衍生物及其制备方法和用途
WO2024204554A1 (ja) * 2023-03-29 2024-10-03 日本ケミファ株式会社 スピロ環状モルヒナン誘導体

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20060984A1 (it) 2006-05-18 2007-11-19 Dipharma Spa Procedimento per la preparazione di arilossipropilammine
US7999104B2 (en) 2007-06-29 2011-08-16 Brock University Methods for one-pot N-demethylation/N-acylation of morphine and tropane alkaloids
CA2709882A1 (en) * 2007-12-17 2009-06-25 Peter X. Wang N-demethylation of n-methyl morphinans
EP2231674A1 (en) * 2007-12-17 2010-09-29 Mallinckrodt Inc. Processes for the preparation of normorphinan salts
PL2222678T3 (pl) * 2007-12-17 2016-09-30 Sposoby wytwarzania związków morfinanowych (+)-'nal'
AU2009233315B2 (en) * 2008-03-31 2013-08-29 Sun Pharmaceutical Industries Ltd. An improved process for the preparation of morphinane analogues
US8691989B2 (en) 2008-06-20 2014-04-08 Phoenix Pharmalabs, Inc. Methods of synthesis of morphinans
US8624030B2 (en) * 2010-08-04 2014-01-07 Mallinckrodt Llc N-demethylation of 6-keto morphinans

Also Published As

Publication number Publication date
US20120035367A1 (en) 2012-02-09
CA2806620A1 (en) 2012-02-09
AU2011285839B2 (en) 2014-05-29
WO2012018871A1 (en) 2012-02-09
JP2013532730A (ja) 2013-08-19
AU2011285839A1 (en) 2013-03-21
EP2601195B1 (en) 2014-04-23
ES2465340T3 (es) 2014-06-05
US8703949B2 (en) 2014-04-22
EP2601195A1 (en) 2013-06-12

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