PL2603507T3 - Synteza związków tiazolidynodionu - Google Patents

Synteza związków tiazolidynodionu

Info

Publication number
PL2603507T3
PL2603507T3 PL11745671.5T PL11745671T PL2603507T3 PL 2603507 T3 PL2603507 T3 PL 2603507T3 PL 11745671 T PL11745671 T PL 11745671T PL 2603507 T3 PL2603507 T3 PL 2603507T3
Authority
PL
Poland
Prior art keywords
synthesis
thiazolidinedione compounds
thiazolidinedione
compounds
Prior art date
Application number
PL11745671.5T
Other languages
English (en)
Inventor
Steven P. Tanis
Timothy Parker
Robert C. Gadwood
James R. Zeller
Gerald D. Artman Iii
Scott D. Larsen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of PL2603507T3 publication Critical patent/PL2603507T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PL11745671.5T 2010-08-10 2011-08-09 Synteza związków tiazolidynodionu PL2603507T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37226910P 2010-08-10 2010-08-10

Publications (1)

Publication Number Publication Date
PL2603507T3 true PL2603507T3 (pl) 2016-12-30

Family

ID=44504274

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11745671.5T PL2603507T3 (pl) 2010-08-10 2011-08-09 Synteza związków tiazolidynodionu

Country Status (14)

Country Link
US (2) US8895748B2 (pl)
EP (1) EP2603507B1 (pl)
JP (1) JP5851506B2 (pl)
KR (1) KR101857307B1 (pl)
CN (1) CN103153991B (pl)
AU (1) AU2011289627B2 (pl)
CA (1) CA2807815C (pl)
ES (1) ES2588769T3 (pl)
HU (1) HUE029488T2 (pl)
MX (1) MX342289B (pl)
NZ (1) NZ606597A (pl)
PL (1) PL2603507T3 (pl)
RU (1) RU2594725C2 (pl)
WO (1) WO2012021467A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2560956T3 (pl) 2010-04-19 2017-03-31 Octeta Therapeutics, Llc Nowa synteza związków tiazolidynodionowych
CA2807662C (en) * 2010-08-10 2019-10-08 Metabolic Solutions Development Company, Llc Synthesis for thiazolidinedione compounds
CN104496935A (zh) * 2014-11-24 2015-04-08 苏州乔纳森新材料科技有限公司 一种胰岛素增敏剂中间体的合成方法
WO2017172368A1 (en) 2016-03-31 2017-10-05 Oncternal Therapeutics, Inc. Indoline analogs and uses thereof

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1003445B (zh) 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物,其制备方法和用途
SU1766260A3 (ru) * 1989-11-04 1992-09-30 Пфайзер Инк (Фирма) Способ получени производных тиазолидиндиона-2,4 или их фармацевтически приемлемых солей с щелочными металлами
US5143930A (en) 1990-02-07 1992-09-01 Sankyo Company, Limited Thiazolidine derivatives with anti-diabetic activity, their preparation and their use
KR100249988B1 (ko) * 1991-04-11 2000-04-01 로렌스 티. 마이젠헬더 티아졸리딘디온 유도체, 그의 제조방법 및 용도
SE9702305D0 (sv) 1997-06-17 1997-06-17 Astra Ab New thiazolidinedione, oxazolidinedione and oxadiazolidinedione derivatives
AP869A (en) 1998-01-05 2000-09-04 Pfizer 2,3-Substituted indole compounds as anti-inflammatory and analgesic agents.
US7407978B2 (en) 1999-04-06 2008-08-05 Theracos, Inc. Heterocyclic analogs of diphenylethylene compounds
US6768008B2 (en) 2000-04-24 2004-07-27 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
WO2002043807A2 (en) 2000-12-01 2002-06-06 Novartis Ag Combinations of an angiotensin receptor antagonist and an anti-hypertensive drug or a statin, for the treatment of sexual dysfunction
WO2003029251A1 (en) 2001-09-28 2003-04-10 Biocon Limited Novel process for the synthesis of thiazolidinedione derivatives
FR2861069B1 (fr) 2003-10-17 2005-12-09 Galderma Res & Dev NOUVEAUX LIGANDS ACTIVATEURS DES RECEPTEURS RARs, UTILISATION EN MEDECINE HUMAINE AINSI QU'EN COSMETIQUE
EP2902026B1 (en) * 2006-03-16 2017-10-04 Metabolic Solutions Development Company LLC Thiazolidinedione analogues for the treatment of metabolic inflammation mediated disease
WO2008118327A1 (en) 2007-03-23 2008-10-02 University Of Toledo Conformationally restrained epothilone analogues as anti-leukemic agents
CN101848901B (zh) 2007-09-14 2012-11-21 新陈代谢解决方案开发公司 用于治疗高血压的噻唑烷二酮类似物
WO2009148195A1 (en) 2008-06-02 2009-12-10 Daebong Ls, Ltd. 5-(4-hydroxybenzyl)thiazolidine-2,4-dione as intermediate for synthesis of thiazolidinedione based compounds and process for preparing the same
PL2560956T3 (pl) 2010-04-19 2017-03-31 Octeta Therapeutics, Llc Nowa synteza związków tiazolidynodionowych
CN103153972A (zh) 2010-04-19 2013-06-12 新陈代谢解决方案开发公司 噻唑烷二酮化合物的新的合成方法
CA2807662C (en) 2010-08-10 2019-10-08 Metabolic Solutions Development Company, Llc Synthesis for thiazolidinedione compounds

Also Published As

Publication number Publication date
AU2011289627A1 (en) 2013-02-21
ES2588769T3 (es) 2016-11-04
EP2603507A1 (en) 2013-06-19
US8946435B2 (en) 2015-02-03
NZ606597A (en) 2014-12-24
MX342289B (es) 2016-09-23
CA2807815A1 (en) 2012-02-16
CN103153991B (zh) 2016-06-29
US20130211092A1 (en) 2013-08-15
US20140378687A1 (en) 2014-12-25
KR101857307B1 (ko) 2018-05-11
AU2011289627B2 (en) 2015-01-15
EP2603507B1 (en) 2016-06-29
CN103153991A (zh) 2013-06-12
JP2013535503A (ja) 2013-09-12
RU2013110311A (ru) 2014-09-20
RU2594725C2 (ru) 2016-08-20
HUE029488T2 (en) 2017-02-28
MX2013001475A (es) 2013-04-29
CA2807815C (en) 2018-10-02
JP5851506B2 (ja) 2016-02-03
KR20130097750A (ko) 2013-09-03
WO2012021467A1 (en) 2012-02-16
US8895748B2 (en) 2014-11-25

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