PL2620156T3 - Kompozycja farmaceutyczna do zapobiegania lub leczenia chorób immunologicznych lub chorób zapalnych, zawierająca komórki macierzyste traktowane agonistą NOD2 lub jego produktem hodowlanym - Google Patents

Kompozycja farmaceutyczna do zapobiegania lub leczenia chorób immunologicznych lub chorób zapalnych, zawierająca komórki macierzyste traktowane agonistą NOD2 lub jego produktem hodowlanym

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Publication number
PL2620156T3
PL2620156T3 PL11820139T PL11820139T PL2620156T3 PL 2620156 T3 PL2620156 T3 PL 2620156T3 PL 11820139 T PL11820139 T PL 11820139T PL 11820139 T PL11820139 T PL 11820139T PL 2620156 T3 PL2620156 T3 PL 2620156T3
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PL
Poland
Prior art keywords
preventing
pharmaceutical composition
stem cells
cells treated
diseases
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Application number
PL11820139T
Other languages
English (en)
Inventor
Kyung Sun Kang
Hyung Sik Kim
Original Assignee
Kang Stem Biotech Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Kang Stem Biotech Co Ltd filed Critical Kang Stem Biotech Co Ltd
Publication of PL2620156T3 publication Critical patent/PL2620156T3/pl

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
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    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C—CHEMISTRY; METALLURGY
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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0665—Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/052—Lipopolysaccharides [LPS]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/05—Adjuvants
    • C12N2501/054—Muramyle peptides

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  • Immunology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Developmental Biology & Embryology (AREA)
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  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Rheumatology (AREA)
  • Virology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
PL11820139T 2010-08-23 2011-08-19 Kompozycja farmaceutyczna do zapobiegania lub leczenia chorób immunologicznych lub chorób zapalnych, zawierająca komórki macierzyste traktowane agonistą NOD2 lub jego produktem hodowlanym PL2620156T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20100081640 2010-08-23
PCT/KR2011/006109 WO2012026712A2 (ko) 2010-08-23 2011-08-19 Ｎｏｄ２의 아고니스트를 처리한 줄기세포 또는 그 배양물을 포함하는 면역질환 또는 염증질환의 예방 또는 치료용 약학조성물
EP11820139.1A EP2620156B1 (en) 2010-08-23 2011-08-19 Pharmaceutical composition for preventing or treating immune diseases or inflammatory diseases, containing stem cells treated with nod2 agonist or cultured product thereof

Publications (1)

Publication Number Publication Date
PL2620156T3 true PL2620156T3 (pl) 2019-10-31

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PL11820139T PL2620156T3 (pl) 2010-08-23 2011-08-19 Kompozycja farmaceutyczna do zapobiegania lub leczenia chorób immunologicznych lub chorób zapalnych, zawierająca komórki macierzyste traktowane agonistą NOD2 lub jego produktem hodowlanym

Country Status (8)

Country Link
US (1) US9408873B2 (pl)
EP (1) EP2620156B1 (pl)
JP (1) JP5805195B2 (pl)
KR (4) KR101480362B1 (pl)
CN (2) CN105727250B (pl)
ES (1) ES2727030T3 (pl)
PL (1) PL2620156T3 (pl)
WO (1) WO2012026712A2 (pl)

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WO2013125899A1 (ko) * 2012-02-22 2013-08-29 주식회사 강스템홀딩스 줄기세포를 유효 성분으로 함유하는 면역 질환 또는 염증 질환의 예방 또는 치료용 조성물
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EP2716298A1 (en) * 2012-10-03 2014-04-09 Institut Pasteur A nod2-dependant pathway of cytoprotection of stem cells
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KR102084974B1 (ko) 2013-07-30 2020-03-06 코아스템(주) 인간 골수 유래 중간엽 줄기세포를 유효성분으로 포함하는 자가면역질환의 예방 또는 치료용 약제학적 조성물
SG11201704640SA (en) * 2015-01-12 2017-07-28 Agency Science Tech & Res Monoclonal antibody against muramyl peptides in prevention and treatment of immune-mediated diseases
JP7057557B2 (ja) * 2015-07-31 2022-04-20 国立大学法人大阪大学 上皮疾患に対する治療及び／又は予防有効性を評価する方法、上皮疾患治療剤のスクリーニング方法、及び上皮疾患治療剤
HRP20230865T1 (hr) * 2015-07-31 2023-11-10 Exotropin, Llc Kompozicije egzosoma i postupci za njihovu pripremu i primjenu za reguliranje i kondicioniranje kože i kose
EP3344613B1 (en) * 2015-08-31 2020-03-04 Dong-A Socio Holdings Co., Ltd. Heteroaryl compounds and their use as therapeutic drugs
WO2017171491A1 (ko) * 2016-03-31 2017-10-05 재단법인 아산사회복지재단 줄기세포 추출물을 포함하는 염증성 질환의 예방 또는 치료용 약학 조성물
WO2017190145A1 (en) 2016-04-29 2017-11-02 Icahn School Of Medicine At Mount Sinai Targeting the innate immune system to induce long-term tolerance and to resolve macrophage accumulation in atherosclerosis
US10913730B2 (en) 2016-10-10 2021-02-09 Dong-A Socio Holdings Co., Ltd. Heteroaryl compounds and their use as Mer inhibitors
EP3669884B1 (en) 2017-08-16 2023-10-18 Sungkwang Medical Foundation Composition for treatment of thyroid associated ophthalmopathy, comprising mesenchymal stem cell
JP7330994B2 (ja) * 2017-11-21 2023-08-22 アイカーン スクール オブ メディスン アット マウント サイナイ 治療用ナノ生物学的組成物による訓練免疫の促進
CN110090228A (zh) * 2018-04-18 2019-08-06 浙江大学 人羊膜上皮细胞在自身免疫性疾病中的治疗用途
JP6497827B1 (ja) * 2018-07-17 2019-04-10 株式会社 バイオミメティクスシンパシーズ エイコサノイド産生促進剤
KR20210053303A (ko) * 2018-08-31 2021-05-11 더 존스 홉킨스 유니버시티 신경퇴행성 장애를 치료하기 위한 rip 키나제의 억제
CN110075269B (zh) * 2019-04-19 2021-06-29 中国人民解放军第二军医大学 Murabutide在制备电离辐射致骨髓、小肠和脾脏损伤防治药物中应用
RU2704322C1 (ru) * 2019-06-11 2019-10-28 Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") Крем с секретомом мультипотентных мезенхимальных стромальных клеток для коррекции псориазиформного воспаления в эксперименте
CN115087455A (zh) * 2019-11-12 2022-09-20 奥查德疗法(欧洲)有限公司 用于治疗或预防克罗恩病的组合物和方法
CN118459539B (zh) 2021-03-19 2026-01-06 生物治疗探索股份有限公司 用于调节训练免疫的化合物及其使用方法
CN115120619A (zh) * 2021-03-23 2022-09-30 苏州大学 一种治疗动脉粥样硬化的干细胞药物
CN113827618B (zh) * 2021-10-20 2023-09-26 上海交通大学医学院附属仁济医院 干细胞条件培养基在制备用于治疗炎症性皮肤的药物中的用途
TWI893486B (zh) * 2022-10-20 2025-08-11 南韓商東亞Ｓｔ股份有限公司 稠合雙環化合物及其等作為mer及axl抑制劑的用途
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CN103118691B (zh) 2016-08-24
KR20140019461A (ko) 2014-02-14
ES2727030T3 (es) 2019-10-11
CN105727250B (zh) 2023-11-07
US20130209422A1 (en) 2013-08-15
JP2013536222A (ja) 2013-09-19
WO2012026712A2 (ko) 2012-03-01
KR20120018724A (ko) 2012-03-05
EP2620156A4 (en) 2014-08-20
JP5805195B2 (ja) 2015-11-04
EP2620156A2 (en) 2013-07-31
WO2012026712A3 (ko) 2012-05-24
KR101480362B1 (ko) 2015-01-28
WO2012026712A4 (ko) 2012-08-23
CN105727250A (zh) 2016-07-06
US9408873B2 (en) 2016-08-09
CN103118691A (zh) 2013-05-22
KR20170091064A (ko) 2017-08-08
EP2620156B1 (en) 2019-03-27
KR20190089812A (ko) 2019-07-31

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