PL2621494T3 - Zastosowanie stearynianu magnezu w preparatach w postaci suchego proszku do inhalacji - Google Patents
Zastosowanie stearynianu magnezu w preparatach w postaci suchego proszku do inhalacjiInfo
- Publication number
- PL2621494T3 PL2621494T3 PL11767661T PL11767661T PL2621494T3 PL 2621494 T3 PL2621494 T3 PL 2621494T3 PL 11767661 T PL11767661 T PL 11767661T PL 11767661 T PL11767661 T PL 11767661T PL 2621494 T3 PL2621494 T3 PL 2621494T3
- Authority
- PL
- Poland
- Prior art keywords
- inhalation
- magnesium stearate
- dry powder
- powder formulations
- formulations
- Prior art date
Links
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 title 2
- 238000009472 formulation Methods 0.000 title 1
- 235000019359 magnesium stearate Nutrition 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000000843 powder Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5015—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Otolaryngology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10183018 | 2010-09-30 | ||
| PCT/EP2011/066062 WO2012041717A1 (en) | 2010-09-30 | 2011-09-16 | Use of magnesium stearate in dry powder formulations for inhalation |
| EP11767661.9A EP2621494B1 (en) | 2010-09-30 | 2011-09-16 | Use of magnesium stearate in dry powder formulations for inhalation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2621494T3 true PL2621494T3 (pl) | 2019-04-30 |
Family
ID=43618674
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL11767661T PL2621494T3 (pl) | 2010-09-30 | 2011-09-16 | Zastosowanie stearynianu magnezu w preparatach w postaci suchego proszku do inhalacji |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US20120082727A1 (pl) |
| EP (1) | EP2621494B1 (pl) |
| KR (2) | KR20140005150A (pl) |
| CN (1) | CN103298470B (pl) |
| AR (1) | AR083208A1 (pl) |
| BR (1) | BR112013007022B1 (pl) |
| CA (1) | CA2813096C (pl) |
| ES (1) | ES2704688T3 (pl) |
| PL (1) | PL2621494T3 (pl) |
| RU (1) | RU2580890C2 (pl) |
| TR (1) | TR201901644T4 (pl) |
| WO (1) | WO2012041717A1 (pl) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9925282B2 (en) | 2009-01-29 | 2018-03-27 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
| GB0918249D0 (en) | 2009-10-19 | 2009-12-02 | Respivert Ltd | Compounds |
| WO2011120779A1 (en) | 2010-04-01 | 2011-10-06 | Chiesi Farmaceutici S.P.A. | Process for preparing carrier particles for dry powders for inhalation |
| UY33337A (es) | 2010-10-18 | 2011-10-31 | Respivert Ltd | DERIVADOS SUSTITUIDOS DE 1H-PIRAZOL[ 3,4-d]PIRIMIDINA COMO INHIBIDORES DE LAS FOSFOINOSITIDA 3-QUINASAS |
| NZ627963A (en) | 2012-03-13 | 2015-08-28 | Respivert Ltd | Dry powder pharmaceutical formulations for inhalation of a compound that inhibits pi3 kinase |
| KR20140147891A (ko) | 2012-04-13 | 2014-12-30 | 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 | 응집체 입자 |
| US10058530B2 (en) | 2012-10-25 | 2018-08-28 | The General Hospital Corporation | Combination therapies for the treatment of Alzheimer's disease and related disorders |
| CN104869993B (zh) | 2012-10-25 | 2019-01-15 | 通用医疗公司 | 治疗阿尔茨海默病及相关疾病的组合疗法 |
| WO2014106727A1 (en) * | 2013-01-03 | 2014-07-10 | Vectura Limited | Inhaler and formulation |
| GB201305825D0 (en) * | 2013-03-28 | 2013-05-15 | Vectura Ltd | New use |
| US10525005B2 (en) | 2013-05-23 | 2020-01-07 | The General Hospital Corporation | Cromolyn compositions and methods thereof |
| AU2014340182B2 (en) * | 2013-10-22 | 2019-05-23 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
| US20190240194A1 (en) | 2016-08-31 | 2019-08-08 | The General Hospital Corporation | Macrophages/microglia in neuro-inflammation associated with neurodegenerative diseases |
| CN111565711B (zh) | 2017-07-20 | 2023-01-03 | 阿茨治疗股份有限公司 | 色甘酸钠和布洛芬的粉末化制剂 |
| CA3076353A1 (en) * | 2017-09-22 | 2019-03-28 | Otitopic Inc. | Dry powder compositions with magnesium stearate |
| KR20210071943A (ko) | 2018-07-02 | 2021-06-16 | 더 제너럴 하스피탈 코포레이션 | 크로몰린 소듐 및 α-락토스의 분말화된 제형 |
| US12383528B2 (en) | 2018-12-10 | 2025-08-12 | The General Hospital Corporation | Cromolyn esters and uses thereof |
| WO2021207060A1 (en) | 2020-04-06 | 2021-10-14 | The General Hospital Corporation | Methods of treatment of coronavirus-induced inflammation conditions |
| US12612391B2 (en) | 2020-12-28 | 2026-04-28 | The General Hospital Corporation | Cromolyn derivatives and uses thereof |
| CN116617402A (zh) * | 2022-02-10 | 2023-08-22 | 北京新领先医药科技发展有限公司 | 一种降低药物中美拉德反应的制备方法 |
| WO2023224577A1 (en) * | 2022-05-18 | 2023-11-23 | Arven Ilac Sanayi Ve Ticaret Anonim Sirketi | Inhalation compositions comprising micronized human insulin |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1150895C (zh) * | 1998-11-13 | 2004-05-26 | 杰格研究股份公司 | 用于吸入给药的干粉 |
| PT1158958E (pt) | 1999-03-05 | 2007-08-13 | Chiesi Farma Spa | ''composições farmacêuticas em pó, melhoradas, para inalação'' |
| PE20011227A1 (es) | 2000-04-17 | 2002-01-07 | Chiesi Farma Spa | Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros |
| PT1386630E (pt) | 2002-07-31 | 2006-09-29 | Chiesi Farma Spa | Inalador em po |
| US20060147389A1 (en) * | 2004-04-14 | 2006-07-06 | Vectura Ltd. | Devices and pharmaceutical compositions for enhancing dosing efficiency |
| JP2009513529A (ja) | 2003-07-11 | 2009-04-02 | グラクソ グループ リミテッド | ステアリン酸マグネシウムを含む医薬製剤 |
| GB0613161D0 (en) * | 2006-06-30 | 2006-08-09 | Novartis Ag | Organic Compounds |
| GB0714134D0 (en) * | 2007-07-19 | 2007-08-29 | Norton Healthcare Ltd | Dry-powder medicament |
| US7590021B2 (en) | 2007-07-26 | 2009-09-15 | Qualcomm Incorporated | System and method to reduce dynamic RAM power consumption via the use of valid data indicators |
| EP2022783A1 (en) | 2007-08-08 | 2009-02-11 | CHIESI FARMACEUTICI S.p.A. | "Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors" |
| EP2154136A1 (en) | 2008-08-08 | 2010-02-17 | CHIESI FARMACEUTICI S.p.A. | Quinuclidine carbonate derivatives and medicinal compositions thereof |
-
2011
- 2011-09-16 WO PCT/EP2011/066062 patent/WO2012041717A1/en not_active Ceased
- 2011-09-16 TR TR2019/01644T patent/TR201901644T4/tr unknown
- 2011-09-16 KR KR1020137007256A patent/KR20140005150A/ko not_active Ceased
- 2011-09-16 RU RU2013113965/15A patent/RU2580890C2/ru active
- 2011-09-16 CA CA2813096A patent/CA2813096C/en active Active
- 2011-09-16 CN CN201180047864.3A patent/CN103298470B/zh active Active
- 2011-09-16 KR KR1020177027944A patent/KR101886987B1/ko active Active
- 2011-09-16 ES ES11767661T patent/ES2704688T3/es active Active
- 2011-09-16 EP EP11767661.9A patent/EP2621494B1/en active Active
- 2011-09-16 BR BR112013007022-6A patent/BR112013007022B1/pt active IP Right Grant
- 2011-09-16 PL PL11767661T patent/PL2621494T3/pl unknown
- 2011-09-22 US US13/239,903 patent/US20120082727A1/en not_active Abandoned
- 2011-09-29 AR ARP110103586A patent/AR083208A1/es not_active Application Discontinuation
-
2015
- 2015-07-17 US US14/801,882 patent/US20150320691A1/en not_active Abandoned
-
2018
- 2018-01-12 US US15/869,162 patent/US20180133161A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AR083208A1 (es) | 2013-02-06 |
| KR101886987B1 (ko) | 2018-08-08 |
| HK1187822A1 (en) | 2014-04-17 |
| WO2012041717A1 (en) | 2012-04-05 |
| CN103298470B (zh) | 2015-06-17 |
| ES2704688T3 (es) | 2019-03-19 |
| US20150320691A1 (en) | 2015-11-12 |
| TR201901644T4 (tr) | 2019-02-21 |
| RU2580890C2 (ru) | 2016-04-10 |
| EP2621494A1 (en) | 2013-08-07 |
| US20180133161A1 (en) | 2018-05-17 |
| CA2813096C (en) | 2019-10-29 |
| CN103298470A (zh) | 2013-09-11 |
| BR112013007022B1 (pt) | 2019-10-15 |
| EP2621494B1 (en) | 2018-11-07 |
| BR112013007022A2 (pt) | 2016-06-14 |
| CA2813096A1 (en) | 2012-04-05 |
| KR20170118231A (ko) | 2017-10-24 |
| KR20140005150A (ko) | 2014-01-14 |
| US20120082727A1 (en) | 2012-04-05 |
| RU2013113965A (ru) | 2014-10-10 |
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